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The map label for this gene is thrB [H]

Identifier: 78484389

GI number: 78484389

Start: 51696

End: 52676

Strand: Reverse

Name: thrB [H]

Synonym: Tcr_0043

Alternate gene names: 78484389

Gene position: 52676-51696 (Counterclockwise)

Preceding gene: 78484393

Following gene: 78484388

Centisome position: 2.17

GC content: 42.51

Gene sequence:

>981_bases
ATGCTAAAATATCGCCGTTTATTAAGTCGTAATTTTAACCTTTTCTTAGGACGGTTTGGGATGTCTGTTTATACTGTTGT
GAATCAAGCGGAGTTGGAAGCCTTTTTAGCGGATTTTGATCAAGGCTCTCTGGTCGCATTTGAAGGCATTAGCGCAGGCA
TTGAAAATACCAATTATTTTGTCGACACCACCGCTGGACGGTTTGTTCTGACCATTTTTGAACATCATGATTTTGATGAA
TTACCTTATTTTCTCGACATTATGGCGTTTATGGCCGAGCATCAAATTCCAACCGCCCATCCAAAACCGACGTTAAAAGG
TTCTTATTTGAAAGAACTGAAAGGTAAGCCTGCAGCACTGGTTGAACGTTTAACCGGTTCAGGCGTGGACCATCCGACGC
AAACACAATGTGAAGTCATGGCCGAAAATCTGGCCAAATTCCATTTGGCAGGTCAAGATTATGACCAATTTCGAGCCAAT
GATCGTGACTTGCACTGGATGAAAAACACGTTTCAAGAAATTAAACGTTTTTTGCCAGAAGACGAAACCGCGTTAATCGA
ATCGGAAATCCATTATCAAAACAACATTGATTGGTCACAACTCCCAAACAGTGTCATCCATGCCGATTTATTCTGTGATA
ACGCCTTATTTAATGGGGATGAGTTGTCCGGCATCATTGATCTTTATTACGCTTGTAACTCTGCCATGCTCTACGATTTG
GCGGTGATGGTGAATGATTGGTGTCGTTTACCGGACTTCAGTCTCAGCACAGAAAAAGTGCATGCGGTGTTAAAGGCGTA
TCAGGCAGTTCGCACTCTGACGGAGCAAGAACAGCAATCCTGGAAAGCAGCTCTTAGAATGGGCGCATTACGTTTCTTCT
TATCGCGTTTGAAAGATAAGCATATGCCGAGAGAAGGCGAAATGACGCAAATCAAAGACCCAAATGTCTTCAAAAACCTA
TTGATATCCCACCGAAAGTAA

Upstream 100 bases:

>100_bases
CCCGGAACAGGTAAGACGAGCCGTCAACTAAGATAAAAGGACTGTCTGGATTGAATTCAGGAAGGATTTGAGTCATTGAA
TGCTTTGCCTCTAAAGGATT

Downstream 100 bases:

>100_bases
GACAAAACTAATCTCGTAATCAAAAAATTCTATCGAAAAAACAGTAACTTTTTTAGTATTTTTGGGTCTGTATTGTTATA
TTGATGTAACAAAAATATAA

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MLKYRRLLSRNFNLFLGRFGMSVYTVVNQAELEAFLADFDQGSLVAFEGISAGIENTNYFVDTTAGRFVLTIFEHHDFDE
LPYFLDIMAFMAEHQIPTAHPKPTLKGSYLKELKGKPAALVERLTGSGVDHPTQTQCEVMAENLAKFHLAGQDYDQFRAN
DRDLHWMKNTFQEIKRFLPEDETALIESEIHYQNNIDWSQLPNSVIHADLFCDNALFNGDELSGIIDLYYACNSAMLYDL
AVMVNDWCRLPDFSLSTEKVHAVLKAYQAVRTLTEQEQQSWKAALRMGALRFFLSRLKDKHMPREGEMTQIKDPNVFKNL
LISHRK

Sequences:

>Translated_326_residues
MLKYRRLLSRNFNLFLGRFGMSVYTVVNQAELEAFLADFDQGSLVAFEGISAGIENTNYFVDTTAGRFVLTIFEHHDFDE
LPYFLDIMAFMAEHQIPTAHPKPTLKGSYLKELKGKPAALVERLTGSGVDHPTQTQCEVMAENLAKFHLAGQDYDQFRAN
DRDLHWMKNTFQEIKRFLPEDETALIESEIHYQNNIDWSQLPNSVIHADLFCDNALFNGDELSGIIDLYYACNSAMLYDL
AVMVNDWCRLPDFSLSTEKVHAVLKAYQAVRTLTEQEQQSWKAALRMGALRFFLSRLKDKHMPREGEMTQIKDPNVFKNL
LISHRK
>Mature_326_residues
MLKYRRLLSRNFNLFLGRFGMSVYTVVNQAELEAFLADFDQGSLVAFEGISAGIENTNYFVDTTAGRFVLTIFEHHDFDE
LPYFLDIMAFMAEHQIPTAHPKPTLKGSYLKELKGKPAALVERLTGSGVDHPTQTQCEVMAENLAKFHLAGQDYDQFRAN
DRDLHWMKNTFQEIKRFLPEDETALIESEIHYQNNIDWSQLPNSVIHADLFCDNALFNGDELSGIIDLYYACNSAMLYDL
AVMVNDWCRLPDFSLSTEKVHAVLKAYQAVRTLTEQEQQSWKAALRMGALRFFLSRLKDKHMPREGEMTQIKDPNVFKNL
LISHRK

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 37534; Mature: 37534

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKYRRLLSRNFNLFLGRFGMSVYTVVNQAELEAFLADFDQGSLVAFEGISAGIENTNYF
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEE
VDTTAGRFVLTIFEHHDFDELPYFLDIMAFMAEHQIPTAHPKPTLKGSYLKELKGKPAAL
EECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHH
VERLTGSGVDHPTQTQCEVMAENLAKFHLAGQDYDQFRANDRDLHWMKNTFQEIKRFLPE
HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCC
DETALIESEIHYQNNIDWSQLPNSVIHADLFCDNALFNGDELSGIIDLYYACNSAMLYDL
CCHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHH
AVMVNDWCRLPDFSLSTEKVHAVLKAYQAVRTLTEQEQQSWKAALRMGALRFFLSRLKDK
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HMPREGEMTQIKDPNVFKNLLISHRK
CCCCCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MLKYRRLLSRNFNLFLGRFGMSVYTVVNQAELEAFLADFDQGSLVAFEGISAGIENTNYF
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEE
VDTTAGRFVLTIFEHHDFDELPYFLDIMAFMAEHQIPTAHPKPTLKGSYLKELKGKPAAL
EECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHH
VERLTGSGVDHPTQTQCEVMAENLAKFHLAGQDYDQFRANDRDLHWMKNTFQEIKRFLPE
HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCC
DETALIESEIHYQNNIDWSQLPNSVIHADLFCDNALFNGDELSGIIDLYYACNSAMLYDL
CCHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHH
AVMVNDWCRLPDFSLSTEKVHAVLKAYQAVRTLTEQEQQSWKAALRMGALRFFLSRLKDK
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HMPREGEMTQIKDPNVFKNLLISHRK
CCCCCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA