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The map label for this gene is rfbG [H]

Identifier: 78358734

GI number: 78358734

Start: 3657024

End: 3658130

Strand: Direct

Name: rfbG [H]

Synonym: Dde_3695

Alternate gene names: 78358734

Gene position: 3657024-3658130 (Clockwise)

Preceding gene: 78358733

Following gene: 78358735

Centisome position: 98.04

GC content: 62.24

Gene sequence:

>1107_bases
ATGTTTGCTGATGTCTACGAAGGCGCCCGCGTTCTGGTGACAGGACATACCGGATTCAAGGGTTCGTGGCTCACTGCGTG
GCTGCTGGAACTGGGCGCCACGGTGGCAGGGTTTGCCGACGGCGTTCCCACCAGTCCCTCGGGGTACGCGGCCATGGGGC
TGGAAAACCGCATAACCACCTACACGGGCGATATCCGCGACAGAGACGCCGTGCAGGCGGCTTTTGCCGATTTCCGTCCG
CAATTTGTCTTTCATATGGCGGCACAGGCGCTTGTACGCCGCTCATACAGAGAACCGGCAGCCACGTTTGCCACCAACGC
CATGGGCACACTGAACGTCATGGAAGCCGTACGCACCACGCCGGAGGTCCGCGTGGTGGTAAGCATTACCAGCGACAAGT
GCTACCGCAATGACGAATGGGTGTGGGGCTACCGCGAAACAGACCACCTCGGGGGCGACGACCCGTACAGCGCGTCAAAA
GCCTGTGCGGAAATTGTAGCCCATTCGTATATAACCTCGTTTTTCACATCCGGCCCGCGCTGTGCAACGGTGCGTGCAGG
CAATGTCATAGGCGGGGGAGACTGGGCCGAAGACCGCATCGTGCCCGACTGCGCGCGGGCATGGGCCGCCGGTGAACCTG
TCATAATCCGCAATCCTTCCGCAACCAGACCGTGGCAGCATGTGCTCGAACCGCTGTCAGGGTATCTGTGGCTGGGGGCC
GGACTGGCGGCAGAATCAGCAGCTACGGCCGAAAACCCGCTGCACGGTCAGGCATTCAACTTCGGGCCGCCGGCAGAGGT
TATCCGTACTGTAGGCGACGTGGTGGGCGAACTGGGCGCACATTGGCCGGGATTTACCGCCCGGCTGGGCACGCCGCCCG
CGCACGAGGCGGAATGCACCCTGCTCAAGCTGTGCTGCGACAAGGCGCTGGCACGGCTGGGCTGGCGCGCTGTGCTGCGC
CACGAAGAAACCGTGCGCTTTACGGCCGAGTGGTATAATGCCTTTTATTCCGGCGCATCGGGTGATATGTCCGCTTTCAC
CACCGGCCAGATAGCGGAATATGTCCGCAAGGCCCGACAGGGAGGATTGCCGTGGACATCATGCTGA

Upstream 100 bases:

>100_bases
GGCTTCTGGCATTGCATGGACACCCTGCGCGACTATAACGACCTGAACGCCATGTGGAACAGCGGCAGCGCACCGTGGGC
CGCAACAGCAGGAGGCTCCG

Downstream 100 bases:

>100_bases
ACACCGCAGATATAAGCGCAGCAGCCATACTGCTGCCCGTCGAGGGGGCGCAGCTTTCCGAGCTGCGTCAGATACCGGCT
GAAGGCGGCCCCGTGCTGCA

Product: CDP-glucose-4,6-dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MFADVYEGARVLVTGHTGFKGSWLTAWLLELGATVAGFADGVPTSPSGYAAMGLENRITTYTGDIRDRDAVQAAFADFRP
QFVFHMAAQALVRRSYREPAATFATNAMGTLNVMEAVRTTPEVRVVVSITSDKCYRNDEWVWGYRETDHLGGDDPYSASK
ACAEIVAHSYITSFFTSGPRCATVRAGNVIGGGDWAEDRIVPDCARAWAAGEPVIIRNPSATRPWQHVLEPLSGYLWLGA
GLAAESAATAENPLHGQAFNFGPPAEVIRTVGDVVGELGAHWPGFTARLGTPPAHEAECTLLKLCCDKALARLGWRAVLR
HEETVRFTAEWYNAFYSGASGDMSAFTTGQIAEYVRKARQGGLPWTSC

Sequences:

>Translated_368_residues
MFADVYEGARVLVTGHTGFKGSWLTAWLLELGATVAGFADGVPTSPSGYAAMGLENRITTYTGDIRDRDAVQAAFADFRP
QFVFHMAAQALVRRSYREPAATFATNAMGTLNVMEAVRTTPEVRVVVSITSDKCYRNDEWVWGYRETDHLGGDDPYSASK
ACAEIVAHSYITSFFTSGPRCATVRAGNVIGGGDWAEDRIVPDCARAWAAGEPVIIRNPSATRPWQHVLEPLSGYLWLGA
GLAAESAATAENPLHGQAFNFGPPAEVIRTVGDVVGELGAHWPGFTARLGTPPAHEAECTLLKLCCDKALARLGWRAVLR
HEETVRFTAEWYNAFYSGASGDMSAFTTGQIAEYVRKARQGGLPWTSC
>Mature_368_residues
MFADVYEGARVLVTGHTGFKGSWLTAWLLELGATVAGFADGVPTSPSGYAAMGLENRITTYTGDIRDRDAVQAAFADFRP
QFVFHMAAQALVRRSYREPAATFATNAMGTLNVMEAVRTTPEVRVVVSITSDKCYRNDEWVWGYRETDHLGGDDPYSASK
ACAEIVAHSYITSFFTSGPRCATVRAGNVIGGGDWAEDRIVPDCARAWAAGEPVIIRNPSATRPWQHVLEPLSGYLWLGA
GLAAESAATAENPLHGQAFNFGPPAEVIRTVGDVVGELGAHWPGFTARLGTPPAHEAECTLLKLCCDKALARLGWRAVLR
HEETVRFTAEWYNAFYSGASGDMSAFTTGQIAEYVRKARQGGLPWTSC

Specific function: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE O-SIDE CHAINS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI48994969, Length=353, Percent_Identity=24.0793201133144, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115532424, Length=350, Percent_Identity=24, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013445
- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =4.2.1.45 [H]

Molecular weight: Translated: 39865; Mature: 39865

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFADVYEGARVLVTGHTGFKGSWLTAWLLELGATVAGFADGVPTSPSGYAAMGLENRITT
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCCEEECCCCCCEE
YTGDIRDRDAVQAAFADFRPQFVFHMAAQALVRRSYREPAATFATNAMGTLNVMEAVRTT
EECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHCC
PEVRVVVSITSDKCYRNDEWVWGYRETDHLGGDDPYSASKACAEIVAHSYITSFFTSGPR
CCEEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
CATVRAGNVIGGGDWAEDRIVPDCARAWAAGEPVIIRNPSATRPWQHVLEPLSGYLWLGA
EEEEECCCEECCCCCCCCCCCHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCEEECC
GLAAESAATAENPLHGQAFNFGPPAEVIRTVGDVVGELGAHWPGFTARLGTPPAHEAECT
CHHHHCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHH
LLKLCCDKALARLGWRAVLRHEETVRFTAEWYNAFYSGASGDMSAFTTGQIAEYVRKARQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
GGLPWTSC
CCCCCCCC
>Mature Secondary Structure
MFADVYEGARVLVTGHTGFKGSWLTAWLLELGATVAGFADGVPTSPSGYAAMGLENRITT
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCCEEECCCCCCEE
YTGDIRDRDAVQAAFADFRPQFVFHMAAQALVRRSYREPAATFATNAMGTLNVMEAVRTT
EECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHCC
PEVRVVVSITSDKCYRNDEWVWGYRETDHLGGDDPYSASKACAEIVAHSYITSFFTSGPR
CCEEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
CATVRAGNVIGGGDWAEDRIVPDCARAWAAGEPVIIRNPSATRPWQHVLEPLSGYLWLGA
EEEEECCCEECCCCCCCCCCCHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCEEECC
GLAAESAATAENPLHGQAFNFGPPAEVIRTVGDVVGELGAHWPGFTARLGTPPAHEAECT
CHHHHCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHH
LLKLCCDKALARLGWRAVLRHEETVRFTAEWYNAFYSGASGDMSAFTTGQIAEYVRKARQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
GGLPWTSC
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609 [H]