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The map label for this gene is rfbF [H]

Identifier: 78358733

GI number: 78358733

Start: 3656243

End: 3657034

Strand: Direct

Name: rfbF [H]

Synonym: Dde_3694

Alternate gene names: 78358733

Gene position: 3656243-3657034 (Clockwise)

Preceding gene: 78358732

Following gene: 78358734

Centisome position: 98.02

GC content: 56.57

Gene sequence:

>792_bases
ATGAAAGTCATCATCATGTGCGGCGGCAAAGGAACCCGCCTGCGCGAAGAAACGGGAACACGCCCCAAGCCCATGCTGGA
CATCGGCGGACGCCCCATTCTGTGGCACATCATGGATATATACGCCCGGCAGGGCTTCAAGGACTTCATCCTGCCGCTGG
GTTACAAAGGCGACATGATCAAGCAGTATTTCTGGGAATACAAAATACGCAACTCCGATTTCACCATAGATCTTGCCTCC
GGCAACATGACCACACACAACAGCTGCCCCACCGACTGGCGCGTAACCATGTGCGACACCGGACAGGACACCATGAAGGG
CGCACGCATCAGTCAGGTGGCGCGCCACATTGACACGCAGCGGTTCATGGTGACCTACGGCGACGGTGTGGCTGACATTG
ATCTGCACGCCCTGCTGGATTTCCATATCCGTTCAGGCAACACGGGCACATTCACGGGAGTGCGCATGCCTTCGCGCTTC
GGGGCCGTACAGACTGACGAGCAGGGCAACATTCTGTCATGGCAGGAAAAACCTGTACTCAACGAATACATCAACTGCGG
CTTTTTCGTCTTTGAACGCGAGTTTCTGAACTACCTTTCCGATGATCCGTCCTGCGACCTTGAAAAAGAACCGCTTGAGC
GTCTTGCCGCAGAAGGCAGACTGGGCATGTACCCCCATGACGGCTTCTGGCATTGCATGGACACCCTGCGCGACTATAAC
GACCTGAACGCCATGTGGAACAGCGGCAGCGCACCGTGGGCCGCAACAGCAGGAGGCTCCGATGTTTGCTGA

Upstream 100 bases:

>100_bases
TCGAATTTTTCCGCTCCGCCGGACGGCGGCACGCGGCACACCATACCGGGCAGCCTTAACAGCCGGCTGCAAACAGCAGA
ACAACCGCAAGGATACTCGC

Downstream 100 bases:

>100_bases
TGTCTACGAAGGCGCCCGCGTTCTGGTGACAGGACATACCGGATTCAAGGGTTCGTGGCTCACTGCGTGGCTGCTGGAAC
TGGGCGCCACGGTGGCAGGG

Product: glucose-1-phosphate cytidylyl-transferase

Products: NA

Alternate protein names: CDP-glucose pyrophosphorylase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKVIIMCGGKGTRLREETGTRPKPMLDIGGRPILWHIMDIYARQGFKDFILPLGYKGDMIKQYFWEYKIRNSDFTIDLAS
GNMTTHNSCPTDWRVTMCDTGQDTMKGARISQVARHIDTQRFMVTYGDGVADIDLHALLDFHIRSGNTGTFTGVRMPSRF
GAVQTDEQGNILSWQEKPVLNEYINCGFFVFEREFLNYLSDDPSCDLEKEPLERLAAEGRLGMYPHDGFWHCMDTLRDYN
DLNAMWNSGSAPWAATAGGSDVC

Sequences:

>Translated_263_residues
MKVIIMCGGKGTRLREETGTRPKPMLDIGGRPILWHIMDIYARQGFKDFILPLGYKGDMIKQYFWEYKIRNSDFTIDLAS
GNMTTHNSCPTDWRVTMCDTGQDTMKGARISQVARHIDTQRFMVTYGDGVADIDLHALLDFHIRSGNTGTFTGVRMPSRF
GAVQTDEQGNILSWQEKPVLNEYINCGFFVFEREFLNYLSDDPSCDLEKEPLERLAAEGRLGMYPHDGFWHCMDTLRDYN
DLNAMWNSGSAPWAATAGGSDVC
>Mature_263_residues
MKVIIMCGGKGTRLREETGTRPKPMLDIGGRPILWHIMDIYARQGFKDFILPLGYKGDMIKQYFWEYKIRNSDFTIDLAS
GNMTTHNSCPTDWRVTMCDTGQDTMKGARISQVARHIDTQRFMVTYGDGVADIDLHALLDFHIRSGNTGTFTGVRMPSRF
GAVQTDEQGNILSWQEKPVLNEYINCGFFVFEREFLNYLSDDPSCDLEKEPLERLAAEGRLGMYPHDGFWHCMDTLRDYN
DLNAMWNSGSAPWAATAGGSDVC

Specific function: Involved in the biosynthesis of the tyvelose, a 3,6- dideoxyhexose found in the O-antigen of the surface lipopolysaccharides. It catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate. This enzyme can utilize either CTP or UTP as the nucle

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate cytidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI11761619, Length=244, Percent_Identity=27.8688524590164, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI11761621, Length=244, Percent_Identity=27.8688524590164, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355443, Length=242, Percent_Identity=26.0330578512397, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644084, Length=242, Percent_Identity=26.0330578512397, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013446
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.33 [H]

Molecular weight: Translated: 29868; Mature: 29868

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIIMCGGKGTRLREETGTRPKPMLDIGGRPILWHIMDIYARQGFKDFILPLGYKGDMI
CEEEEEECCCCCEEHHHCCCCCCCEEECCCCHHHHHHHHHHHHCCCHHHHCCCCCCCHHH
KQYFWEYKIRNSDFTIDLASGNMTTHNSCPTDWRVTMCDTGQDTMKGARISQVARHIDTQ
HHHHHHEEECCCCEEEEEECCCCEECCCCCCCCEEEEECCCCHHHCCHHHHHHHHHHCCC
RFMVTYGDGVADIDLHALLDFHIRSGNTGTFTGVRMPSRFGAVQTDEQGNILSWQEKPVL
EEEEEECCCCCCCCCEEEEEEEEECCCCCEEEEEECCHHCCCEEECCCCCEECCCCCCHH
NEYINCGFFVFEREFLNYLSDDPSCDLEKEPLERLAAEGRLGMYPHDGFWHCMDTLRDYN
HHHHCCCCEEEHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
DLNAMWNSGSAPWAATAGGSDVC
HHHHHHCCCCCCEEECCCCCCCC
>Mature Secondary Structure
MKVIIMCGGKGTRLREETGTRPKPMLDIGGRPILWHIMDIYARQGFKDFILPLGYKGDMI
CEEEEEECCCCCEEHHHCCCCCCCEEECCCCHHHHHHHHHHHHCCCHHHHCCCCCCCHHH
KQYFWEYKIRNSDFTIDLASGNMTTHNSCPTDWRVTMCDTGQDTMKGARISQVARHIDTQ
HHHHHHEEECCCCEEEEEECCCCEECCCCCCCCEEEEECCCCHHHCCHHHHHHHHHHCCC
RFMVTYGDGVADIDLHALLDFHIRSGNTGTFTGVRMPSRFGAVQTDEQGNILSWQEKPVL
EEEEEECCCCCCCCCEEEEEEEEECCCCCEEEEEECCHHCCCEEECCCCCEECCCCCCHH
NEYINCGFFVFEREFLNYLSDDPSCDLEKEPLERLAAEGRLGMYPHDGFWHCMDTLRDYN
HHHHCCCCEEEHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
DLNAMWNSGSAPWAATAGGSDVC
HHHHHHCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]