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The map label for this gene is potC

Identifier: 78358711

GI number: 78358711

Start: 3632198

End: 3632968

Strand: Direct

Name: potC

Synonym: Dde_3672

Alternate gene names: 78358711

Gene position: 3632198-3632968 (Clockwise)

Preceding gene: 78358710

Following gene: 78358712

Centisome position: 97.37

GC content: 56.55

Gene sequence:

>771_bases
ATGAAAATCCTGCGCCGGACCTACATGTGGGCGGTCTACGCCTTTCTGTACATTCCCATTCTGGTGGTCATTGCCTATTC
CGTCAACAACGCGAAATACACCACAGACTGGAAAGGCTTTACATGGAAGTGGTATCAGCAGCTGTTCAGCAACCAGCAGC
TGATGGACGCCGCCGCAAACTCGCTCATGGTGGCCACCGTTGCCGCCACCTGCGCCACCGTGCTGGGCACGCTGGCCGCC
CTGTGCATACACCGCTACCGCTTTACCGGACGCAAGGTGCTGCACGGCCTCACGTATGTGCTTACGGTGTCGCCCGATAT
CGTCATGGGCATCTCGCTTCTCATCTTTTTCATTTTCTTTCATATCGAGCTTGGTTTCGGCACGCTGCTGGCAGCGCACA
TCACGCTGTGCCTGCCTTTTGTCACGGTGACGGTACTGGGCCGCTTTTCGGAATTCGATGAAGATGTGGTGGCTGCAGCC
AAAGACCTCGGCGCATCAGAAGGACAGGCCTTCCGCCATGTCATTCTGCCGCTTATCATGCCTGCCGTCATGGCAGGCTG
GCTGCTCAGTTTCACACTTTCCATGGACGACGTGCTCATCAGCTTCTTTGTAACGGGGCCGAACTTTGATATTCTGCCCC
TGCGCATCTATTCCATGGTCAGGCTGGGCGTAAAGCCCGACATCAACGCGCTGAGCGCGGTTCTGTTCTGCCTGACAATC
GTACTGGTACTGCTGGCCCACACCCTTAGCAAGGCAAGGAGACGCCCATGA

Upstream 100 bases:

>100_bases
TGACTCTTATCCTCGTGGTACTTATTCTGCTGTACTATATGGCAAAAAAACGCAGCGCCACGCATCACAAGGATGATGAA
CTGTACGGGGAGGGCATGTG

Downstream 100 bases:

>100_bases
AAAAGCTCTTCGCCGTCATCCTGACGGTCATGCTGTGTCCGTTTTTTGCCCAGAACGCTCTGGCGCAGGATGAAAAAATC
CTCAATGTGTACAACTGGTC

Product: spermidine/putrescine ABC transporter membrane protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKILRRTYMWAVYAFLYIPILVVIAYSVNNAKYTTDWKGFTWKWYQQLFSNQQLMDAAANSLMVATVAATCATVLGTLAA
LCIHRYRFTGRKVLHGLTYVLTVSPDIVMGISLLIFFIFFHIELGFGTLLAAHITLCLPFVTVTVLGRFSEFDEDVVAAA
KDLGASEGQAFRHVILPLIMPAVMAGWLLSFTLSMDDVLISFFVTGPNFDILPLRIYSMVRLGVKPDINALSAVLFCLTI
VLVLLAHTLSKARRRP

Sequences:

>Translated_256_residues
MKILRRTYMWAVYAFLYIPILVVIAYSVNNAKYTTDWKGFTWKWYQQLFSNQQLMDAAANSLMVATVAATCATVLGTLAA
LCIHRYRFTGRKVLHGLTYVLTVSPDIVMGISLLIFFIFFHIELGFGTLLAAHITLCLPFVTVTVLGRFSEFDEDVVAAA
KDLGASEGQAFRHVILPLIMPAVMAGWLLSFTLSMDDVLISFFVTGPNFDILPLRIYSMVRLGVKPDINALSAVLFCLTI
VLVLLAHTLSKARRRP
>Mature_256_residues
MKILRRTYMWAVYAFLYIPILVVIAYSVNNAKYTTDWKGFTWKWYQQLFSNQQLMDAAANSLMVATVAATCATVLGTLAA
LCIHRYRFTGRKVLHGLTYVLTVSPDIVMGISLLIFFIFFHIELGFGTLLAAHITLCLPFVTVTVLGRFSEFDEDVVAAA
KDLGASEGQAFRHVILPLIMPAVMAGWLLSFTLSMDDVLISFFVTGPNFDILPLRIYSMVRLGVKPDINALSAVLFCLTI
VLVLLAHTLSKARRRP

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=254, Percent_Identity=51.1811023622047, Blast_Score=262, Evalue=2e-71,
Organism=Escherichia coli, GI1787081, Length=254, Percent_Identity=38.9763779527559, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1787714, Length=237, Percent_Identity=34.1772151898734, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1788764, Length=232, Percent_Identity=29.7413793103448, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28594; Mature: 28594

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]