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The map label for this gene is dinB [H]

Identifier: 78358660

GI number: 78358660

Start: 3581837

End: 3582994

Strand: Reverse

Name: dinB [H]

Synonym: Dde_3621

Alternate gene names: 78358660

Gene position: 3582994-3581837 (Counterclockwise)

Preceding gene: 78358666

Following gene: 78358654

Centisome position: 96.05

GC content: 61.83

Gene sequence:

>1158_bases
ATGCATATTGATATGGATGCCTTTTTCGCATCTGTCGAGCAGCTGGACAATGCTGCGCTGCGCGGCCGTCCTGTGGTTGT
GGGCGGGGGCAAGCGCGGGGTTGTTGCCGCCGCCTCGTACGAAGCGCGGCGCTACGGCATCCGTTCGGCCATGCCTTCGG
GGCAGGCGCGCAGGCTGTGTCCGCATGCGGTGTTTGTCAAAGGCCGTATGCACCGGTACAAAGAGATATCCGCACAGGTC
ATGCAGGTGCTGCATGAATTTTCGCCGCTGGTGGAGCAGGCCTCGGTGGATGAGGCGTATCTGGACGCCACCGGCAGCGC
ACGGTTGTTCGGTCCGCCGGAAGAAATGGCCCGGCGCATACGCGCTGCCGTGCGTGAGGCTGTTTCGCTTACCTGTTCGG
TAGGGGTTGCGCCGGTCAAGTTTCTGGCAAAAATCGCTTCGGACGTGAACAAGCCGGACGGGCTGTTTGTGCTGCAACCT
GATGAGGTTGCCGGTTTTCTGGCGGTGCTGCCTGTGGGCGACATTCCCGGTGTGGGGCGGCATTTTGCCGGTCAGTTGCA
GGCGCTGGGGGTGCGTACTGCCGGTGACGTGCTGCGTTATCCCGAAACATTCTGGCAGCGCCGTTTCGGCAAGGGCGGGC
TGGGGCTTTTTGCCAGGGCGCAGGGCATTGACCCCCGCGTGGTGGAACCGTACACGCAGGCCAAGTCGGAAAGTGCCGAA
AACACCTTTGAGGAAGATACGGATGACCGGGAACTGCTGAAGACCTGGCTTTTGAAGCAGGCGGAACGGGTGGGGCGGAA
TCAGCGGCGCATGGGGCTTTCCGGCCGTACTGTGACGCTGAAAGTGAAGTTTGCCGACTTCAGAACGGTGACCCGCAGCA
GAACGCTTGCCGCACCCACAAGCAGCACAAGGGTCATCTATGATACCGCCGCAGCGCTGCTGGACGAGATGGGCCTGCCG
CAGAAGGTCCGGCTTATCGGGGTGGGCCTGTCACATTACGCCGAAGGACCGCAGCAGCTGGCATTGCCGCTGTGTTCTCC
CGCCGCTGTGCGTGACGAAAAAAGCGAGCAGCTGGAAAAGACCATGGATGCCGTGCGCGACAGGTTCGGTTCCGCTGCCA
TCGTGCGGGGCAGATTGTTCGGCTTCGGCAAAGATTAG

Upstream 100 bases:

>100_bases
GCCTCGGGCGGTGTTCCGGAGGCGGGCAGCGCGTTCCGCTCTTTTGTGCCGGAAGAGCATCTGGTATGACGGTGGCATGA
GTCAGTGGACACGGTGTATC

Downstream 100 bases:

>100_bases
CCCGGCTACATGTCGGGACTGCGCGGGTACGGTCTTTTTTCCGGTTTTCTTTTGTAGCAGTCCCGGGTTTTACACAGTGT
CGGGTAGCGGCTTGTAATTT

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MHIDMDAFFASVEQLDNAALRGRPVVVGGGKRGVVAAASYEARRYGIRSAMPSGQARRLCPHAVFVKGRMHRYKEISAQV
MQVLHEFSPLVEQASVDEAYLDATGSARLFGPPEEMARRIRAAVREAVSLTCSVGVAPVKFLAKIASDVNKPDGLFVLQP
DEVAGFLAVLPVGDIPGVGRHFAGQLQALGVRTAGDVLRYPETFWQRRFGKGGLGLFARAQGIDPRVVEPYTQAKSESAE
NTFEEDTDDRELLKTWLLKQAERVGRNQRRMGLSGRTVTLKVKFADFRTVTRSRTLAAPTSSTRVIYDTAAALLDEMGLP
QKVRLIGVGLSHYAEGPQQLALPLCSPAAVRDEKSEQLEKTMDAVRDRFGSAAIVRGRLFGFGKD

Sequences:

>Translated_385_residues
MHIDMDAFFASVEQLDNAALRGRPVVVGGGKRGVVAAASYEARRYGIRSAMPSGQARRLCPHAVFVKGRMHRYKEISAQV
MQVLHEFSPLVEQASVDEAYLDATGSARLFGPPEEMARRIRAAVREAVSLTCSVGVAPVKFLAKIASDVNKPDGLFVLQP
DEVAGFLAVLPVGDIPGVGRHFAGQLQALGVRTAGDVLRYPETFWQRRFGKGGLGLFARAQGIDPRVVEPYTQAKSESAE
NTFEEDTDDRELLKTWLLKQAERVGRNQRRMGLSGRTVTLKVKFADFRTVTRSRTLAAPTSSTRVIYDTAAALLDEMGLP
QKVRLIGVGLSHYAEGPQQLALPLCSPAAVRDEKSEQLEKTMDAVRDRFGSAAIVRGRLFGFGKD
>Mature_385_residues
MHIDMDAFFASVEQLDNAALRGRPVVVGGGKRGVVAAASYEARRYGIRSAMPSGQARRLCPHAVFVKGRMHRYKEISAQV
MQVLHEFSPLVEQASVDEAYLDATGSARLFGPPEEMARRIRAAVREAVSLTCSVGVAPVKFLAKIASDVNKPDGLFVLQP
DEVAGFLAVLPVGDIPGVGRHFAGQLQALGVRTAGDVLRYPETFWQRRFGKGGLGLFARAQGIDPRVVEPYTQAKSESAE
NTFEEDTDDRELLKTWLLKQAERVGRNQRRMGLSGRTVTLKVKFADFRTVTRSRTLAAPTSSTRVIYDTAAALLDEMGLP
QKVRLIGVGLSHYAEGPQQLALPLCSPAAVRDEKSEQLEKTMDAVRDRFGSAAIVRGRLFGFGKD

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=339, Percent_Identity=29.2035398230088, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI7706681, Length=340, Percent_Identity=29.1176470588235, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI154350220, Length=246, Percent_Identity=29.2682926829268, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI7705344, Length=104, Percent_Identity=41.3461538461538, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI5729982, Length=116, Percent_Identity=37.0689655172414, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI1786425, Length=336, Percent_Identity=41.6666666666667, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1787432, Length=400, Percent_Identity=28.75, Blast_Score=105, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI193205700, Length=401, Percent_Identity=33.1670822942643, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI193205702, Length=234, Percent_Identity=37.1794871794872, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17537959, Length=197, Percent_Identity=26.9035532994924, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI115534089, Length=118, Percent_Identity=38.135593220339, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19923006, Length=400, Percent_Identity=25.25, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI21355641, Length=312, Percent_Identity=25, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24644984, Length=312, Percent_Identity=25, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24668444, Length=124, Percent_Identity=38.7096774193548, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 42085; Mature: 42085

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIDMDAFFASVEQLDNAALRGRPVVVGGGKRGVVAAASYEARRYGIRSAMPSGQARRLC
CCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCHHHHHHHHHHCCCCCCHHHHC
PHAVFVKGRMHRYKEISAQVMQVLHEFSPLVEQASVDEAYLDATGSARLFGPPEEMARRI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEECCCHHHHHHHH
RAAVREAVSLTCSVGVAPVKFLAKIASDVNKPDGLFVLQPDEVAGFLAVLPVGDIPGVGR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCHHHCCEEEEEECCCCCCCCH
HFAGQLQALGVRTAGDVLRYPETFWQRRFGKGGLGLFARAQGIDPRVVEPYTQAKSESAE
HHHHHHHHHCCCCHHHHHHCCHHHHHHHCCCCCCCHHHCCCCCCCCCCCCHHHHHCCCHH
NTFEEDTDDRELLKTWLLKQAERVGRNQRRMGLSGRTVTLKVKFADFRTVTRSRTLAAPT
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEEEEECHHHHHHHCCEEECCC
SSTRVIYDTAAALLDEMGLPQKVRLIGVGLSHYAEGPQQLALPLCSPAAVRDEKSEQLEK
CCCEEEHHHHHHHHHHCCCCCEEEEEEECHHHHHCCHHHHHCCCCCCHHHCCCHHHHHHH
TMDAVRDRFGSAAIVRGRLFGFGKD
HHHHHHHHHCCEEEEEHHHCCCCCC
>Mature Secondary Structure
MHIDMDAFFASVEQLDNAALRGRPVVVGGGKRGVVAAASYEARRYGIRSAMPSGQARRLC
CCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCHHHHHHHHHHCCCCCCHHHHC
PHAVFVKGRMHRYKEISAQVMQVLHEFSPLVEQASVDEAYLDATGSARLFGPPEEMARRI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEECCCHHHHHHHH
RAAVREAVSLTCSVGVAPVKFLAKIASDVNKPDGLFVLQPDEVAGFLAVLPVGDIPGVGR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCHHHCCEEEEEECCCCCCCCH
HFAGQLQALGVRTAGDVLRYPETFWQRRFGKGGLGLFARAQGIDPRVVEPYTQAKSESAE
HHHHHHHHHCCCCHHHHHHCCHHHHHHHCCCCCCCHHHCCCCCCCCCCCCHHHHHCCCHH
NTFEEDTDDRELLKTWLLKQAERVGRNQRRMGLSGRTVTLKVKFADFRTVTRSRTLAAPT
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEEEEECHHHHHHHCCEEECCC
SSTRVIYDTAAALLDEMGLPQKVRLIGVGLSHYAEGPQQLALPLCSPAAVRDEKSEQLEK
CCCEEEHHHHHHHHHHCCCCCEEEEEEECHHHHHCCHHHHHCCCCCCHHHCCCHHHHHHH
TMDAVRDRFGSAAIVRGRLFGFGKD
HHHHHHHHHCCEEEEEHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA