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The map label for this gene is trpE(G) [H]

Identifier: 78358656

GI number: 78358656

Start: 3578329

End: 3578877

Strand: Direct

Name: trpE(G) [H]

Synonym: Dde_3617

Alternate gene names: 78358656

Gene position: 3578329-3578877 (Clockwise)

Preceding gene: 78358655

Following gene: 78358657

Centisome position: 95.93

GC content: 62.3

Gene sequence:

>549_bases
ATGCTCCGCATACTGCTTTCCGACAACGACGACAGCTTCACCATGAATCTGGCGCACCTGCTGCACGCCGCCACAGGCAG
CACCCCGCAGGTGGTCAACCATACGGCGCTGGCTGCCCGTGCCCCCGCAGCAGAGCAGGACCTTGTGGTCATATCTCCCG
GTCCGGGGCATCCCGATGAATACCCGTGCTACGGGCCGGTGCTGCAAAGCGGCAGGCCGGTACTGGGCATATGTCTGGGC
ATGCAGATTATCAACTGCCACTTCGGCGGCACGGTGAAAGCGCTGGCAGGGTGCGTGCACGGAAAATCCGACACCGTTGT
GATGACCGATGCGGACAAGACCCTGACCGTGGGGCGCTATCACTCACTGCACTGCGCCACAACCGGAGCGGGACTGCAGG
TCACGGGGCGTACGCCTCAGGGGCTTGTCATGGCGCTGCGGCATAATTCCCTGCCCCTGTACGGGTATCAGTTCCACCCC
GAATCGTTTCTGACAGCCGAAGGAGTCTGGTGCATCCGCCATGCGCTGCGTTCTCTGCATATCCTGTGA

Upstream 100 bases:

>100_bases
TGTGCACGTGGTCGCTGCCCGACATGTTCTTTTCATACCGCCGCGCCAAGGCTTCGGGCAGGCAGGCAGCCTTCATCTGG
ATCGAGCGCTGAAAAACAAC

Downstream 100 bases:

>100_bases
TCCGCGGTGCATTCCTCCGCTGCTGGATTTTCTGGCCCGGAGGCATCATGCCGACATGCTTCTTTCGGCACCTCCGGCCC
GCGCAGAATCCTGTGCAGAC

Product: aminodeoxychorismate synthase, glutamine amidotransferase subunit

Products: NA

Alternate protein names: Glutamine amidotransferase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MLRILLSDNDDSFTMNLAHLLHAATGSTPQVVNHTALAARAPAAEQDLVVISPGPGHPDEYPCYGPVLQSGRPVLGICLG
MQIINCHFGGTVKALAGCVHGKSDTVVMTDADKTLTVGRYHSLHCATTGAGLQVTGRTPQGLVMALRHNSLPLYGYQFHP
ESFLTAEGVWCIRHALRSLHIL

Sequences:

>Translated_182_residues
MLRILLSDNDDSFTMNLAHLLHAATGSTPQVVNHTALAARAPAAEQDLVVISPGPGHPDEYPCYGPVLQSGRPVLGICLG
MQIINCHFGGTVKALAGCVHGKSDTVVMTDADKTLTVGRYHSLHCATTGAGLQVTGRTPQGLVMALRHNSLPLYGYQFHP
ESFLTAEGVWCIRHALRSLHIL
>Mature_182_residues
MLRILLSDNDDSFTMNLAHLLHAATGSTPQVVNHTALAARAPAAEQDLVVISPGPGHPDEYPCYGPVLQSGRPVLGICLG
MQIINCHFGGTVKALAGCVHGKSDTVVMTDADKTLTVGRYHSLHCATTGAGLQVTGRTPQGLVMALRHNSLPLYGYQFHP
ESFLTAEGVWCIRHALRSLHIL

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=188, Percent_Identity=36.7021276595745, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789760, Length=177, Percent_Identity=38.9830508474576, Blast_Score=91, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=35.8288770053476, Blast_Score=97, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281365319, Length=129, Percent_Identity=34.1085271317829, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR010112
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 19441; Mature: 19441

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRILLSDNDDSFTMNLAHLLHAATGSTPQVVNHTALAARAPAAEQDLVVISPGPGHPDE
CEEEEEECCCCCEEHHHHHHHHHCCCCCCHHHCCHHHHHCCCCCCCCEEEECCCCCCCCC
YPCYGPVLQSGRPVLGICLGMQIINCHFGGTVKALAGCVHGKSDTVVMTDADKTLTVGRY
CCCCCHHHHCCCCEEEHEECEEEEEEECCCHHHHHHHHHCCCCCEEEEECCCCEEEECCE
HSLHCATTGAGLQVTGRTPQGLVMALRHNSLPLYGYQFHPESFLTAEGVWCIRHALRSLH
EEEEEEECCCCEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHC
IL
CC
>Mature Secondary Structure
MLRILLSDNDDSFTMNLAHLLHAATGSTPQVVNHTALAARAPAAEQDLVVISPGPGHPDE
CEEEEEECCCCCEEHHHHHHHHHCCCCCCHHHCCHHHHHCCCCCCCCEEEECCCCCCCCC
YPCYGPVLQSGRPVLGICLGMQIINCHFGGTVKALAGCVHGKSDTVVMTDADKTLTVGRY
CCCCCHHHHCCCCEEEHEECEEEEEEECCCHHHHHHHHHCCCCCEEEEECCCCEEEECCE
HSLHCATTGAGLQVTGRTPQGLVMALRHNSLPLYGYQFHPESFLTAEGVWCIRHALRSLH
EEEEEEECCCCEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHC
IL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8939798 [H]