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The map label for this gene is lldP [C]

Identifier: 78358278

GI number: 78358278

Start: 3230992

End: 3232704

Strand: Direct

Name: lldP [C]

Synonym: Dde_3238

Alternate gene names: 78358278

Gene position: 3230992-3232704 (Clockwise)

Preceding gene: 78358277

Following gene: 78358279

Centisome position: 86.62

GC content: 58.79

Gene sequence:

>1713_bases
ATGTCTGTGGAACTGTTGGCACTTGTTGCCCTCCTGCCGATTCTGGTAGCTCTTGTTCTGATGGTAGGCCTGCGCTGGCC
CGCCACCAAGGCCATGCCCCTTGCATGGCTTGTCTGCGCGCTGGGCGCAATGTTCGCATGGCAGCTGCCTGCCTCCTATG
TGGCAGCTCTTACGCTGCAGGGCTTCATTACGGCCATCGGCATTCTGATCATCGTGTTCGGTGCCATCATCATCCTCTAC
ACGCTGCAGTACTCGGGCGGTATGGAAACCATCCAGTACGGCATGCAGAATATTTCACGTGACCGCCGCGTTCAGGCCAT
CATCATCGGCTACCTGTTCGCGGCGTTCATCGAAGGTGCCGCCGGCTTCGGCACGCCCGCTGCTCTGGCCGCCCCGCTGC
TGCTTTCGCTGGGCTTTCCCCCGCTGGCAGCCGCCGTGCTCTGCCTTGTGTTCAACTCTTTCCCCGTGTCCTTCGGTGCT
GTGGGTACCCCCATCGTACTGGGCATGACCCCGCTCAAGGGGCTGGTGGAAAAAGCCATAGCCACCAACGGCGCCGCACT
GAACTTCACCAGCTTTGACACGTTCAACCTGGTTATCGGTCAGTGGGCCACCGTGATGCACCTCATCATGATCTTCGTGC
TGCCCATTTTCATGCTGGGCTTCATCACCCGTTTCTTCGGCCCCAACCGCAGCTGGTCCGAAGGTTTCGCCGCATGGAAG
TTCTGCATCTTCGCTGCTGTGTCCTTCACCATTCCCTACCTGATCTTTGCATGGTACGTCGGTCCCGAGTTCCCCTCGCT
GATCGGTGGTCTGGTTGGTCTGGGCATCGTTGTGGCAGGCGCCAAGCGCGGTTTCTGCGTACCTGAAAAGAGCTGGGACT
TCGGCGATCCTGAAAAGTGGGATCCTGAGTGGACCGGTGAAATCAAGGGCGGACAGTCCACGGAATTCAAGGCTCACATG
AGCCAGTTCAAGGCATGGCTGCCCTACATCCTTATCGGCGCCATCCTTGTTATCACCCGTATTCCCGAACTGGGCCTCAA
GGGCCTGCTGGCCGGCCAGAAGATTTCCTTCACTGAAATTCTCGGCTACAAGAGCGTCAACGCCAGCATCGCCTACCTGT
ACCTGCCCGGTACCATTCCCTTTGTACTCATCGCCGTGCTGACCATCTTCATTCACGGCATGAAGGGCGACGCAGCCAAG
CGCGCCTGGACCGAATCCATCGCCAAGATGAAAAACCCCGCCATCGCGCTGTTCTTTGCCGTTGGTCTGGTTTCCATCTT
CCGCGGTTCCGGCATTGTTGATGCCGCACTGAACCCCAACAGCTACCCCTCCATGCCGCTGGCCATGGCCAAAACAGTGG
CCGCCATCACCGGCAACGCATGGCCCATGTTCGCATCGTTCGTGGGTGGCCTCGGGTCGTTCATCACCGGCTCCAACACT
GTTTCCGACCTGCTCTTTGCAGAATTCCAGTGGGGCGTGGCACAGCAGCTTGATATGCCGCGTCAGATCATTGTCGCAGC
ACAGGTTGTGGGCGGCGCCATGGGTAACATGGTCTGCATCCACAACATCGTGGCAGCCTGCGCAGTTGTCGGCCTGTCCG
GCATGGAAGGAACAATCCTGAAGCGTACCGCATGGCCTTTCCTGCTGTACGGTCTGGTGGTGGGCGTTGTTGCCTCCGTC
CTCACCTTCGTGATGTTCCCCAACTTGTTCTAA

Upstream 100 bases:

>100_bases
GTGCCGGAAGGGAGCGGAAGCCCTTCCGGCACCCCATAACCGCTAACCGCAGCGGCATGTGGTTCGCCGCTGCAACACCG
CAAACTCAGAGGAGCGTTGT

Downstream 100 bases:

>100_bases
CCCGCACCAAGGGGGCGGAATGCGCGAATTCCGCCCCCCTTTTTGCGGCATGAAACCATATAGGCGACGGAGCGAACTAC
GGTACCTGCTCCGTTTTTTG

Product: L-lactate transport

Products: Proton [Cytoplasm]; lactate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MSVELLALVALLPILVALVLMVGLRWPATKAMPLAWLVCALGAMFAWQLPASYVAALTLQGFITAIGILIIVFGAIIILY
TLQYSGGMETIQYGMQNISRDRRVQAIIIGYLFAAFIEGAAGFGTPAALAAPLLLSLGFPPLAAAVLCLVFNSFPVSFGA
VGTPIVLGMTPLKGLVEKAIATNGAALNFTSFDTFNLVIGQWATVMHLIMIFVLPIFMLGFITRFFGPNRSWSEGFAAWK
FCIFAAVSFTIPYLIFAWYVGPEFPSLIGGLVGLGIVVAGAKRGFCVPEKSWDFGDPEKWDPEWTGEIKGGQSTEFKAHM
SQFKAWLPYILIGAILVITRIPELGLKGLLAGQKISFTEILGYKSVNASIAYLYLPGTIPFVLIAVLTIFIHGMKGDAAK
RAWTESIAKMKNPAIALFFAVGLVSIFRGSGIVDAALNPNSYPSMPLAMAKTVAAITGNAWPMFASFVGGLGSFITGSNT
VSDLLFAEFQWGVAQQLDMPRQIIVAAQVVGGAMGNMVCIHNIVAACAVVGLSGMEGTILKRTAWPFLLYGLVVGVVASV
LTFVMFPNLF

Sequences:

>Translated_570_residues
MSVELLALVALLPILVALVLMVGLRWPATKAMPLAWLVCALGAMFAWQLPASYVAALTLQGFITAIGILIIVFGAIIILY
TLQYSGGMETIQYGMQNISRDRRVQAIIIGYLFAAFIEGAAGFGTPAALAAPLLLSLGFPPLAAAVLCLVFNSFPVSFGA
VGTPIVLGMTPLKGLVEKAIATNGAALNFTSFDTFNLVIGQWATVMHLIMIFVLPIFMLGFITRFFGPNRSWSEGFAAWK
FCIFAAVSFTIPYLIFAWYVGPEFPSLIGGLVGLGIVVAGAKRGFCVPEKSWDFGDPEKWDPEWTGEIKGGQSTEFKAHM
SQFKAWLPYILIGAILVITRIPELGLKGLLAGQKISFTEILGYKSVNASIAYLYLPGTIPFVLIAVLTIFIHGMKGDAAK
RAWTESIAKMKNPAIALFFAVGLVSIFRGSGIVDAALNPNSYPSMPLAMAKTVAAITGNAWPMFASFVGGLGSFITGSNT
VSDLLFAEFQWGVAQQLDMPRQIIVAAQVVGGAMGNMVCIHNIVAACAVVGLSGMEGTILKRTAWPFLLYGLVVGVVASV
LTFVMFPNLF
>Mature_569_residues
SVELLALVALLPILVALVLMVGLRWPATKAMPLAWLVCALGAMFAWQLPASYVAALTLQGFITAIGILIIVFGAIIILYT
LQYSGGMETIQYGMQNISRDRRVQAIIIGYLFAAFIEGAAGFGTPAALAAPLLLSLGFPPLAAAVLCLVFNSFPVSFGAV
GTPIVLGMTPLKGLVEKAIATNGAALNFTSFDTFNLVIGQWATVMHLIMIFVLPIFMLGFITRFFGPNRSWSEGFAAWKF
CIFAAVSFTIPYLIFAWYVGPEFPSLIGGLVGLGIVVAGAKRGFCVPEKSWDFGDPEKWDPEWTGEIKGGQSTEFKAHMS
QFKAWLPYILIGAILVITRIPELGLKGLLAGQKISFTEILGYKSVNASIAYLYLPGTIPFVLIAVLTIFIHGMKGDAAKR
AWTESIAKMKNPAIALFFAVGLVSIFRGSGIVDAALNPNSYPSMPLAMAKTVAAITGNAWPMFASFVGGLGSFITGSNTV
SDLLFAEFQWGVAQQLDMPRQIIVAAQVVGGAMGNMVCIHNIVAACAVVGLSGMEGTILKRTAWPFLLYGLVVGVVASVL
TFVMFPNLF

Specific function: May play a role in L-lactate transport [H]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lactate permease family [H]

Homologues:

Organism=Escherichia coli, GI1790031, Length=587, Percent_Identity=28.1090289608177, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1789347, Length=271, Percent_Identity=31.7343173431734, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003804 [H]

Pfam domain/function: PF02652 Lactate_perm [H]

EC number: NA

Molecular weight: Translated: 60949; Mature: 60818

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVELLALVALLPILVALVLMVGLRWPATKAMPLAWLVCALGAMFAWQLPASYVAALTLQ
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
GFITAIGILIIVFGAIIILYTLQYSGGMETIQYGMQNISRDRRVQAIIIGYLFAAFIEGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
AGFGTPAALAAPLLLSLGFPPLAAAVLCLVFNSFPVSFGAVGTPIVLGMTPLKGLVEKAI
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHH
ATNGAALNFTSFDTFNLVIGQWATVMHLIMIFVLPIFMLGFITRFFGPNRSWSEGFAAWK
HCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
FCIFAAVSFTIPYLIFAWYVGPEFPSLIGGLVGLGIVVAGAKRGFCVPEKSWDFGDPEKW
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
DPEWTGEIKGGQSTEFKAHMSQFKAWLPYILIGAILVITRIPELGLKGLLAGQKISFTEI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCHHHHHCCCCCCHHHH
LGYKSVNASIAYLYLPGTIPFVLIAVLTIFIHGMKGDAAKRAWTESIAKMKNPAIALFFA
HCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHH
VGLVSIFRGSGIVDAALNPNSYPSMPLAMAKTVAAITGNAWPMFASFVGGLGSFITGSNT
HHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHH
VSDLLFAEFQWGVAQQLDMPRQIIVAAQVVGGAMGNMVCIHNIVAACAVVGLSGMEGTIL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHH
KRTAWPFLLYGLVVGVVASVLTFVMFPNLF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SVELLALVALLPILVALVLMVGLRWPATKAMPLAWLVCALGAMFAWQLPASYVAALTLQ
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
GFITAIGILIIVFGAIIILYTLQYSGGMETIQYGMQNISRDRRVQAIIIGYLFAAFIEGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
AGFGTPAALAAPLLLSLGFPPLAAAVLCLVFNSFPVSFGAVGTPIVLGMTPLKGLVEKAI
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHH
ATNGAALNFTSFDTFNLVIGQWATVMHLIMIFVLPIFMLGFITRFFGPNRSWSEGFAAWK
HCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
FCIFAAVSFTIPYLIFAWYVGPEFPSLIGGLVGLGIVVAGAKRGFCVPEKSWDFGDPEKW
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
DPEWTGEIKGGQSTEFKAHMSQFKAWLPYILIGAILVITRIPELGLKGLLAGQKISFTEI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCHHHHHCCCCCCHHHH
LGYKSVNASIAYLYLPGTIPFVLIAVLTIFIHGMKGDAAKRAWTESIAKMKNPAIALFFA
HCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHH
VGLVSIFRGSGIVDAALNPNSYPSMPLAMAKTVAAITGNAWPMFASFVGGLGSFITGSNT
HHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHH
VSDLLFAEFQWGVAQQLDMPRQIIVAAQVVGGAMGNMVCIHNIVAACAVVGLSGMEGTIL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHH
KRTAWPFLLYGLVVGVVASVLTFVMFPNLF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]