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The map label for this gene is sdaA [H]

Identifier: 78358151

GI number: 78358151

Start: 3100444

End: 3101658

Strand: Direct

Name: sdaA [H]

Synonym: Dde_3111

Alternate gene names: 78358151

Gene position: 3100444-3101658 (Clockwise)

Preceding gene: 78358147

Following gene: 78358152

Centisome position: 83.12

GC content: 61.4

Gene sequence:

>1215_bases
ATGGACAGCATAACAGAGCTTTACCGCATCGGCTCCGGCCCTTCTTCCAGCCACACCATGGGACCGCAGAACGCCGCACG
TCTTTTTGTGGAACAGCACCCCGAAGCCGCACGGTTCCGCGTTACCCTGTATGAAAGTCTGGCATCCACAGGCAAAGGCC
ACCTGACCGACCGGGCCGTTACAGCCGCACTGGGCGAAGAGCGCTGTGAAATAGTCTGGAAACCGGAAGAACGCATGCCC
CGGCATCCCAACGGCATGCTGTTTGAAGCGCAGGACAGCAACGGCAACGTAACCGGCAGCTGGAAAGTGTACAGCGTGGG
CGGCGGCGCCATCATGGGCGAAGACGAACCCCGCAGGCAGCAGCAGGGCGTCTACCCGCACCCTGATCTGGCTTCGGTAA
TGGCCCTGTGCGAAGATAAGGGCATAACCTACTGGGAATATGTGGCCCGTTATGAAGGCGAAACCGTATGGCCCTTTTTG
AAAACCATATGGCAGGCCATGCAGCAGGCGCTGGAACGCGGTCTGACTGCGCAGGGAGTTCTGCCCGGTTCCATAGGGCT
GCGCAGGCAGGCATGGAACTATATGTCGCGCACAAAGCTGGCGCACAAAAGCATGCACCAGACCGGCAAGGTGACGGCCT
ATGCGCTGGCCGTGGCAGAAGAAAACGCGGCAGGCGGCATCATAGTCACAGCCCCCACATGCGGTTCATGCGGCATCGTG
CCCGCCGTGCTCTATTACCTGCGCGAAACGCTGAAAGCCACCGAGCAGGATATTCTGCGGGCTCTGGCCACGGCAGGACT
TTTCGGCAACATAATCAAGCACAATGCGTCCATTTCTGGCGCGGAGGTTGGCTGTCAGGGCGAGGTGGGCTCTGCCTGCG
CCATGGCGGCGGCCGCCGCCACCCAGATGATGGGCGGTACGGTGCGGCAGATAGAATACGCTGCCGAAATGGGTCTGGAG
CACCATCTGGGGCTGACATGCGACCCTGTGGACGGGCTGGTGCAGATTCCCTGTATAGAACGTAACGCCTGCGCGGCCAC
CCGTGCCCTTTCCCGTGCGCAGATGGCCATCCTGTCCGACGGCATGCACCGCATTCCCTTTGACGAAGTGGTGGCCGTCA
TGGCCCAGACAGGTCACGACCTGCCCAGCCTGTATCGCGAAACAGCCCGCGGCGGGCTGGCAAAAGTCTATGCCGCACGG
CCGCAGAAGCAGTGA

Upstream 100 bases:

>100_bases
CTGAACAGTACCACTGACAGGCAAGCATGTGACGCCTTTGTTTTCTGTGCTTTTCACGTCCGCCGCATTGCCTGCGCACC
GCCTACAGCCGCGAGGGCAT

Downstream 100 bases:

>100_bases
AATGCCCCCCACGGGTATTCAAAATGCCATTGATATTAAAAAAAAGATAAAAATCGGCATATTATAACGACAACAGCCCG
TAAAAAATAACGATTTCTTG

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MDSITELYRIGSGPSSSHTMGPQNAARLFVEQHPEAARFRVTLYESLASTGKGHLTDRAVTAALGEERCEIVWKPEERMP
RHPNGMLFEAQDSNGNVTGSWKVYSVGGGAIMGEDEPRRQQQGVYPHPDLASVMALCEDKGITYWEYVARYEGETVWPFL
KTIWQAMQQALERGLTAQGVLPGSIGLRRQAWNYMSRTKLAHKSMHQTGKVTAYALAVAEENAAGGIIVTAPTCGSCGIV
PAVLYYLRETLKATEQDILRALATAGLFGNIIKHNASISGAEVGCQGEVGSACAMAAAAATQMMGGTVRQIEYAAEMGLE
HHLGLTCDPVDGLVQIPCIERNACAATRALSRAQMAILSDGMHRIPFDEVVAVMAQTGHDLPSLYRETARGGLAKVYAAR
PQKQ

Sequences:

>Translated_404_residues
MDSITELYRIGSGPSSSHTMGPQNAARLFVEQHPEAARFRVTLYESLASTGKGHLTDRAVTAALGEERCEIVWKPEERMP
RHPNGMLFEAQDSNGNVTGSWKVYSVGGGAIMGEDEPRRQQQGVYPHPDLASVMALCEDKGITYWEYVARYEGETVWPFL
KTIWQAMQQALERGLTAQGVLPGSIGLRRQAWNYMSRTKLAHKSMHQTGKVTAYALAVAEENAAGGIIVTAPTCGSCGIV
PAVLYYLRETLKATEQDILRALATAGLFGNIIKHNASISGAEVGCQGEVGSACAMAAAAATQMMGGTVRQIEYAAEMGLE
HHLGLTCDPVDGLVQIPCIERNACAATRALSRAQMAILSDGMHRIPFDEVVAVMAQTGHDLPSLYRETARGGLAKVYAAR
PQKQ
>Mature_404_residues
MDSITELYRIGSGPSSSHTMGPQNAARLFVEQHPEAARFRVTLYESLASTGKGHLTDRAVTAALGEERCEIVWKPEERMP
RHPNGMLFEAQDSNGNVTGSWKVYSVGGGAIMGEDEPRRQQQGVYPHPDLASVMALCEDKGITYWEYVARYEGETVWPFL
KTIWQAMQQALERGLTAQGVLPGSIGLRRQAWNYMSRTKLAHKSMHQTGKVTAYALAVAEENAAGGIIVTAPTCGSCGIV
PAVLYYLRETLKATEQDILRALATAGLFGNIIKHNASISGAEVGCQGEVGSACAMAAAAATQMMGGTVRQIEYAAEMGLE
HHLGLTCDPVDGLVQIPCIERNACAATRALSRAQMAILSDGMHRIPFDEVVAVMAQTGHDLPSLYRETARGGLAKVYAAR
PQKQ

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=449, Percent_Identity=39.4209354120267, Blast_Score=294, Evalue=8e-81,
Organism=Escherichia coli, GI48994925, Length=455, Percent_Identity=39.5604395604396, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1789161, Length=449, Percent_Identity=37.6391982182628, Blast_Score=275, Evalue=5e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 43651; Mature: 43651

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSITELYRIGSGPSSSHTMGPQNAARLFVEQHPEAARFRVTLYESLASTGKGHLTDRAV
CCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHH
TAALGEERCEIVWKPEERMPRHPNGMLFEAQDSNGNVTGSWKVYSVGGGAIMGEDEPRRQ
HHHHCCCCCEEEECCHHHCCCCCCCCEEEEECCCCCEEEEEEEEEECCCEEECCCCHHHH
QQGVYPHPDLASVMALCEDKGITYWEYVARYEGETVWPFLKTIWQAMQQALERGLTAQGV
HCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
LPGSIGLRRQAWNYMSRTKLAHKSMHQTGKVTAYALAVAEENAAGGIIVTAPTCGSCGIV
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEECCCCCCCCHH
PAVLYYLRETLKATEQDILRALATAGLFGNIIKHNASISGAEVGCQGEVGSACAMAAAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
TQMMGGTVRQIEYAAEMGLEHHLGLTCDPVDGLVQIPCIERNACAATRALSRAQMAILSD
HHHHCCHHHHHHHHHHCCHHHCCCCEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHC
GMHRIPFDEVVAVMAQTGHDLPSLYRETARGGLAKVYAARPQKQ
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCEEHHHCCCCCC
>Mature Secondary Structure
MDSITELYRIGSGPSSSHTMGPQNAARLFVEQHPEAARFRVTLYESLASTGKGHLTDRAV
CCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHH
TAALGEERCEIVWKPEERMPRHPNGMLFEAQDSNGNVTGSWKVYSVGGGAIMGEDEPRRQ
HHHHCCCCCEEEECCHHHCCCCCCCCEEEEECCCCCEEEEEEEEEECCCEEECCCCHHHH
QQGVYPHPDLASVMALCEDKGITYWEYVARYEGETVWPFLKTIWQAMQQALERGLTAQGV
HCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
LPGSIGLRRQAWNYMSRTKLAHKSMHQTGKVTAYALAVAEENAAGGIIVTAPTCGSCGIV
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEECCCCCCCCHH
PAVLYYLRETLKATEQDILRALATAGLFGNIIKHNASISGAEVGCQGEVGSACAMAAAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
TQMMGGTVRQIEYAAEMGLEHHLGLTCDPVDGLVQIPCIERNACAATRALSRAQMAILSD
HHHHCCHHHHHHHHHHCCHHHCCCCEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHC
GMHRIPFDEVVAVMAQTGHDLPSLYRETARGGLAKVYAARPQKQ
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCEEHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]