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The map label for this gene is cbiL [H]

Identifier: 78358147

GI number: 78358147

Start: 3097590

End: 3098309

Strand: Direct

Name: cbiL [H]

Synonym: Dde_3107

Alternate gene names: 78358147

Gene position: 3097590-3098309 (Clockwise)

Preceding gene: 78358146

Following gene: 78358151

Centisome position: 83.04

GC content: 59.17

Gene sequence:

>720_bases
GTGTACGGTACGTTGTACGGTATCGGCGTCGGCCCCGGCGACCCCGACCTGCTTACCATAAAGGCGGTCAAGGCTCTGGC
CCGCACGGACGTGGTCTTTGCCGCCAGTTCCACAAAAAACGATTATTCTGTATCGCTTTCCATAGCCGCCCCGCACCTGC
GGGACGATGTGCAGATTATCCGGCTGGGCTTTCCCATGTCGCGCGACGGCAGCGTGCTGCGTGCTGCGTGGGACGAAAAC
GCACGCACAGTTGCCGGCCATCTGGCTGCCGGACGGCAGTGCGCGTTTCTCACGCTGGGGGACCCGCTCATCTATTCCAC
TTTCGGCTACCTGCTGCGCACTCTGCGCACCGTATGTCCGCAGGCTCCCGTGGAAATCGTGCCGGGCATCACCTCATATC
AGGCGTCGGCCGCACGCACGGCCACCATCCTGTGTGAATCAGGTGAAAACCTGCTGCTGCTTTCCGGCGTGGGTGACGGG
CTGGAACAAGCCCTGAGTTACGCGGACAACGCCGTTATTCTGAAAACGTATAAAAACTTTGCTGCCATCAGAAAGGCTGT
GACCGCAGCAGGCAAAGAAAACCAGAGCACGTTTGTCTCGCGTCTGGGAATGGACGGCGAGATTGTGGCCGAATCACTGC
AGGACGCCCCCGAAAAGCCGCATTACTTTTCGCTGATGCTGGTGACCGGCGATAAAAAGAGAAAAAACGCGGACTCCTGA

Upstream 100 bases:

>100_bases
CCGGCCCCAGAGCGGTGGATGCGGTGGAAGAGCTTGCGCGCTTTCTGCATCCCTCGCGCTTCACCCTGCAGCCCCCGGCT
GCCGGTCAAGGAGAACCCTA

Downstream 100 bases:

>100_bases
CCGGAGCCTGCCGCGCACCATGCGCAGACAACTACATGCAAAGCCCCCCTGCGCCGCCGCATAGCAAAGCGCAGGGGGGT
AACATGTACAGTTGGCTCAG

Product: cobalt-factor II C20-methyltransferase / precorrin-2 C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MYGTLYGIGVGPGDPDLLTIKAVKALARTDVVFAASSTKNDYSVSLSIAAPHLRDDVQIIRLGFPMSRDGSVLRAAWDEN
ARTVAGHLAAGRQCAFLTLGDPLIYSTFGYLLRTLRTVCPQAPVEIVPGITSYQASAARTATILCESGENLLLLSGVGDG
LEQALSYADNAVILKTYKNFAAIRKAVTAAGKENQSTFVSRLGMDGEIVAESLQDAPEKPHYFSLMLVTGDKKRKNADS

Sequences:

>Translated_239_residues
MYGTLYGIGVGPGDPDLLTIKAVKALARTDVVFAASSTKNDYSVSLSIAAPHLRDDVQIIRLGFPMSRDGSVLRAAWDEN
ARTVAGHLAAGRQCAFLTLGDPLIYSTFGYLLRTLRTVCPQAPVEIVPGITSYQASAARTATILCESGENLLLLSGVGDG
LEQALSYADNAVILKTYKNFAAIRKAVTAAGKENQSTFVSRLGMDGEIVAESLQDAPEKPHYFSLMLVTGDKKRKNADS
>Mature_239_residues
MYGTLYGIGVGPGDPDLLTIKAVKALARTDVVFAASSTKNDYSVSLSIAAPHLRDDVQIIRLGFPMSRDGSVLRAAWDEN
ARTVAGHLAAGRQCAFLTLGDPLIYSTFGYLLRTLRTVCPQAPVEIVPGITSYQASAARTATILCESGENLLLLSGVGDG
LEQALSYADNAVILKTYKNFAAIRKAVTAAGKENQSTFVSRLGMDGEIVAESLQDAPEKPHYFSLMLVTGDKKRKNADS

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 25501; Mature: 25501

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGTLYGIGVGPGDPDLLTIKAVKALARTDVVFAASSTKNDYSVSLSIAAPHLRDDVQII
CCCEEEEECCCCCCCCEEHHHHHHHHHHHCEEEEECCCCCCEEEEEEEECCCCCCCEEEE
RLGFPMSRDGSVLRAAWDENARTVAGHLAAGRQCAFLTLGDPLIYSTFGYLLRTLRTVCP
EECCCCCCCCCEEEEECCCCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCC
QAPVEIVPGITSYQASAARTATILCESGENLLLLSGVGDGLEQALSYADNAVILKTYKNF
CCCHHHCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCHHHHHHHHHCCCEEEEEHHHHH
AAIRKAVTAAGKENQSTFVSRLGMDGEIVAESLQDAPEKPHYFSLMLVTGDKKRKNADS
HHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MYGTLYGIGVGPGDPDLLTIKAVKALARTDVVFAASSTKNDYSVSLSIAAPHLRDDVQII
CCCEEEEECCCCCCCCEEHHHHHHHHHHHCEEEEECCCCCCEEEEEEEECCCCCCCEEEE
RLGFPMSRDGSVLRAAWDENARTVAGHLAAGRQCAFLTLGDPLIYSTFGYLLRTLRTVCP
EECCCCCCCCCEEEEECCCCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCC
QAPVEIVPGITSYQASAARTATILCESGENLLLLSGVGDGLEQALSYADNAVILKTYKNF
CCCHHHCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCHHHHHHHHHCCCEEEEEHHHHH
AAIRKAVTAAGKENQSTFVSRLGMDGEIVAESLQDAPEKPHYFSLMLVTGDKKRKNADS
HHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]