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The map label for this gene is glnM [H]

Identifier: 78358111

GI number: 78358111

Start: 3062244

End: 3063173

Strand: Reverse

Name: glnM [H]

Synonym: Dde_3071

Alternate gene names: 78358111

Gene position: 3063173-3062244 (Counterclockwise)

Preceding gene: 78358112

Following gene: 78358110

Centisome position: 82.12

GC content: 61.18

Gene sequence:

>930_bases
ATGAATCCGATGCCGGCCGCCGTGCCGGAGGAGCGCGCCGTGGAATGTGACGGCAGCATGCCGCGCGATGCCGCTGCGAA
GGGCAGATGCAGGGTGCGGCTGCCGGTACGCATCTGGCGCGCGGTGACGGATGCACGGCGTCCGTGGGCGGTGGATATGA
TGCTGTATCTTGCCGTCATGACCGGGGTGGTGTGGTTTACGCTGCGCGGTACGGAACAGCTGGGCTACCACTGGCAGTGG
CACCGTGCCCTGCGCTATCTTGCGGACACGCGCGGCGGATGGCATGCCGGTCCGCTGCTGCAGGGGCTGCTGGTCACCTT
CAAGGTATCGGCCGTCAGCCTGGTTCTGGCAGCCGTCATAGGGCTTGCCGCGGTGCTGCTGCGGCTTTCGCGTTCTGTGG
TGGGGCGGGCTCTTGCTGTCTGTTATCTTGAGACTGTCCGCAATACGCCGCTGCTCATTCAGCTTTTTGTCATGTACTTT
GTGGTGGCCCCGCTGACGGGCATGGACAGGTTTTTTTCCGCCGTGCTCGCGCTCAGCCTGTTTGAAGGCGCCTATATATC
GGAAATAATCCGTGCGGGCATACAGGCTGTACCTGCCGGTCAGTGGGAGGCTGCACGCAGTCTGGGGCTGACCCGCGCGG
CCACTTACCGCAAGGTTGTGCTGCCGCAGGCGCTGGGGCATGTGCTGCCGCCGCTTACCGGGCAGATGGTCACACTGGTT
AAAGATTCGGCGCTGGTAAGCACCATTGCCATTTACGACCTGACCATGCAGGCGCAGGCCATTATTGCAGAAACATTTCT
GGTTTTTGAAATCTGGTTTATGGTGGCTGCCATGTATCTTGTCGTTACGCTCAGTCTTTCACTGCTGGCACAGCGCCTTG
AGTGCCGGCTGAGAACCGGATCAAAGGCATGTCGCAAGGCTGCCGCATAA

Upstream 100 bases:

>100_bases
CTTCGGCACGTGGGAGCGCATCTTTTACGGTGAGTTCGACGGCCGCCGTAAAAAACGCGCACTGGTTAAAATTATCGGGG
AGTGATGCCGGTGCCGCAGT

Downstream 100 bases:

>100_bases
GGAGGATTTGTATGAAACGGATGCTGACTGCGGCGGTTGCCGCCGTGCTGCTGCTTGGTCTGGCCGCCGGAGCCTGGGCC
GATGTGCGGCAGGAACTTAC

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNPMPAAVPEERAVECDGSMPRDAAAKGRCRVRLPVRIWRAVTDARRPWAVDMMLYLAVMTGVVWFTLRGTEQLGYHWQW
HRALRYLADTRGGWHAGPLLQGLLVTFKVSAVSLVLAAVIGLAAVLLRLSRSVVGRALAVCYLETVRNTPLLIQLFVMYF
VVAPLTGMDRFFSAVLALSLFEGAYISEIIRAGIQAVPAGQWEAARSLGLTRAATYRKVVLPQALGHVLPPLTGQMVTLV
KDSALVSTIAIYDLTMQAQAIIAETFLVFEIWFMVAAMYLVVTLSLSLLAQRLECRLRTGSKACRKAAA

Sequences:

>Translated_309_residues
MNPMPAAVPEERAVECDGSMPRDAAAKGRCRVRLPVRIWRAVTDARRPWAVDMMLYLAVMTGVVWFTLRGTEQLGYHWQW
HRALRYLADTRGGWHAGPLLQGLLVTFKVSAVSLVLAAVIGLAAVLLRLSRSVVGRALAVCYLETVRNTPLLIQLFVMYF
VVAPLTGMDRFFSAVLALSLFEGAYISEIIRAGIQAVPAGQWEAARSLGLTRAATYRKVVLPQALGHVLPPLTGQMVTLV
KDSALVSTIAIYDLTMQAQAIIAETFLVFEIWFMVAAMYLVVTLSLSLLAQRLECRLRTGSKACRKAAA
>Mature_309_residues
MNPMPAAVPEERAVECDGSMPRDAAAKGRCRVRLPVRIWRAVTDARRPWAVDMMLYLAVMTGVVWFTLRGTEQLGYHWQW
HRALRYLADTRGGWHAGPLLQGLLVTFKVSAVSLVLAAVIGLAAVLLRLSRSVVGRALAVCYLETVRNTPLLIQLFVMYF
VVAPLTGMDRFFSAVLALSLFEGAYISEIIRAGIQAVPAGQWEAARSLGLTRAATYRKVVLPQALGHVLPPLTGQMVTLV
KDSALVSTIAIYDLTMQAQAIIAETFLVFEIWFMVAAMYLVVTLSLSLLAQRLECRLRTGSKACRKAAA

Specific function: Part of the ABC transporter complex glnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=210, Percent_Identity=38.5714285714286, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788226, Length=209, Percent_Identity=36.3636363636364, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87082239, Length=207, Percent_Identity=36.231884057971, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786874, Length=239, Percent_Identity=30.1255230125523, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787087, Length=144, Percent_Identity=38.8888888888889, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI48994930, Length=123, Percent_Identity=45.5284552845528, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786873, Length=208, Percent_Identity=33.1730769230769, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788645, Length=214, Percent_Identity=30.3738317757009, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788646, Length=220, Percent_Identity=27.7272727272727, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787086, Length=207, Percent_Identity=25.1207729468599, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34003; Mature: 34003

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPMPAAVPEERAVECDGSMPRDAAAKGRCRVRLPVRIWRAVTDARRPWAVDMMLYLAVM
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHH
TGVVWFTLRGTEQLGYHWQWHRALRYLADTRGGWHAGPLLQGLLVTFKVSAVSLVLAAVI
HHHHHEEEECCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLAAVLLRLSRSVVGRALAVCYLETVRNTPLLIQLFVMYFVVAPLTGMDRFFSAVLALSL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FEGAYISEIIRAGIQAVPAGQWEAARSLGLTRAATYRKVVLPQALGHVLPPLTGQMVTLV
HCCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
KDSALVSTIAIYDLTMQAQAIIAETFLVFEIWFMVAAMYLVVTLSLSLLAQRLECRLRTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKACRKAAA
HHHHHHCCC
>Mature Secondary Structure
MNPMPAAVPEERAVECDGSMPRDAAAKGRCRVRLPVRIWRAVTDARRPWAVDMMLYLAVM
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHH
TGVVWFTLRGTEQLGYHWQWHRALRYLADTRGGWHAGPLLQGLLVTFKVSAVSLVLAAVI
HHHHHEEEECCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLAAVLLRLSRSVVGRALAVCYLETVRNTPLLIQLFVMYFVVAPLTGMDRFFSAVLALSL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FEGAYISEIIRAGIQAVPAGQWEAARSLGLTRAATYRKVVLPQALGHVLPPLTGQMVTLV
HCCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
KDSALVSTIAIYDLTMQAQAIIAETFLVFEIWFMVAAMYLVVTLSLSLLAQRLECRLRTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKACRKAAA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 9384377 [H]