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The map label for this gene is rpoC

Identifier: 78358038

GI number: 78358038

Start: 2979009

End: 2983169

Strand: Direct

Name: rpoC

Synonym: Dde_2998

Alternate gene names: 78358038

Gene position: 2979009-2983169 (Clockwise)

Preceding gene: 78358037

Following gene: 78358039

Centisome position: 79.86

GC content: 57.92

Gene sequence:

>4161_bases
ATGACCTTAGACGATCTGTTCTCCATGCGCGGAACCGCTGCCGGCCAGACAAACATCCGCAATCTGAAGGCAATGCAGAT
TTCCATTGCCTCGCCGGAAAGCATTCGCGAATGGTCCTACGGCGAAGTGAAAAAGCCCGAGACCATCAACTACCGTACGT
TCAAGCCGGAACGTGACGGTCTTTTCTGCGCAAAGATTTTCGGCCCCGTAAAGGACTACGAGTGTAACTGCGGTAAATAC
AAGCGCATGAAGCACCGCGGTATCGTGTGTGAAAAATGCGGCGTTGAAGTTATCGCCTCAAAGGTGCGCCGCGAGCGCAT
GGGTCACATAGAACTGGCCGCGCCTGTGGCGCATATCTGGTTCCTCAAGACTCTGCCTTCCAAAATCGGCACCCTGCTCG
ACATGACCATGGCCGATCTGGAAAAGGTGCTCTACTTCGATTCCTACATCGTGCTTGACCCCGGTTCCACCAGTCTTGCC
AAGCTGCAGGTCATTTCCGAAGACCAGTATCTTCAGATCATCGACCATTACGGCGAAGACGCTCTGGTGGTGGGCATGGG
TGCAGAAGCCATCCGCTCGCTGCTGGAAGAACTGAATCTTGAGGCACTGCGGGCCGAACTGCGCGAAGAATCGCAGAGCA
CCCGTTCGCAGACCAAAAAGAAAAAGCTGACCAAGCGCCTGAAAATCGTCGAAGCGTTCCTTGAGTCCGACAACAAGCCC
GAGTGGATGGTGATGGAAGTTGTTCCCGTCATTCCGCCCGAGCTGCGTCCTCTTGTACCGCTGGACGGCGGACGTTTTGC
CACGTCCGACCTGAACGACCTGTACCGCCGCGTCATCAACCGCAACAACCGCCTCAAGCGTCTGATGGAACTGGGTGCGC
CCGATATCATCATCCGCAACGAAAAGCGCATGCTGCAGGAATCGGTTGACGCCCTGTTCGACAACGGCCGCCGCGGCCGC
GCCATCACCGGCACCAACGGCCGTCCCCTCAAGTCCCTTTCCGACATGATCAAGGGTAAACAGGGCCGTTTCCGTCAGAA
CCTGCTGGGCAAGCGTGTCGACTACTCCGGCCGTTCGGTCATTGTGGTCGGTCCCAAGCTTAAACTGCACCAGTGCGGTC
TGCCCAAAAAGATGGCCCTCGAACTCTTCAAGCCCTTCATCTACTCCAAACTGGAAGAAAGGGGACTGGCCTCCACCATC
AAATCTGCAAAGAAAATGGTGGAACGCGAAGAACTGGTCGTGTGGGACATTCTTGAAGAAGTGGTGCGCGAGTACCCCAT
TCTGCTCAACCGTGCGCCCACGCTGCACCGTCTGGGCATTCAGGCATTTGAACCGCTGCTGGTGGAAGGCAAGGCAATCC
AGCTGCATCCGCTGGTCTGCGCCGCCTACAACGCCGACTTTGACGGTGACCAGATGGCCGTCCACGTGCCGCTTTCTGTG
GAAGCACAGATTGAATGCCGCGTGCTCATGATGTCCACCAACAACATTCTTTCGCCGGCAAACGGCACTCCCGTCATCGT
GCCCTCGCAGGACATCGTCCTCGGGCTGTACTACATGACGGTTGAGCGTTCGTTTGAAAAAGGCGAAGGCATGGCTTTCT
GCGCACCGTGGGAAGTGGTGGCCGCATACGATGCCGGCAGCATTTCTCTGCACGCGCGCATCAAGGTGCGCATGCCCGAC
GGCCGTCTGCTGAACACCACTCCCGGCCGTATCATGGTGGGCGAAGTACTGCCCGAAGGCGTGCACTTTGATCTGGTGAA
CACCGTTCTGACCAAAAAGAACATCGCGCGGCTGGTGGGCAATGCTTACCGCGACGCCGGCACCAAGGCCACCGTACTGC
TGTGCGACCGCCTGAAGGATATCGGCTACGAATTCGCCACCCGCGCCGGTGTGACCATCGGCGTCAAGGACATGACCATT
CCCCAAAGCAAGAAGGGCATTCTGGCCGACTCGCAGGCGGAAGTGGACAACATCGAACGCCAGTACCGCGACGGTATCAT
CACCCGCACGGAAAAGTACAACAAGGTTGTGGACGTGTGGACCAAAGCCACGCAGGACATCTCGCAGGAAATGATCAAAG
AGATCTCCTACGATGTCATGCGCGACGAAAAGACGGGCAAAGAAGAGCTGAACCAGAGCTTCAACCCCATCTTCATGATG
TCCAACTCCGGTGCGCGAGGCAACCAGGACCAGATGCGTCAGCTGGCCGGCATGCGTGGTCTTATGGCCAAGCCTTCCGG
TGAAATTATCGAAACCCCGATCACCTCGTGCTTCCGTGAAGGTCTGTCCGTGCTGCAGTACTTCACCTCCACGCACGGCG
CACGTAAGGGTCTGGCGGATACCGCGCTTAAAACCGCGAACTCCGGTTACCTTACCCGTCGTCTGGTTGACGTCGTTCAG
GATGTCATCATCAGCGAACACGACTGCGGCACCGTCGACGGGCTGGAAGTGGGCCACCTTATCAAGGGCGGCGACATCAA
GATGCGCCTTGCAGAACGTGTGCTGGGCCGCGTCACGCTGTATCCGGTGACCGACCCGGAAACCACCGAGGTGCTCTTCC
CGGCCAACACGCTTATTGATGAAAACGTGGCCAAAAAGCTGGACGAGGCAGGCATCAACTCTCTGCATATCCGTTCGGCA
CTTACCTGCCGCTCCGACAGGGGCGTGTGCGCCATGTGCTACGGCCGCGACCTTGCCCGCGGGCATGTGGTCAACATCGG
TGAGACCGTGGGCATCATCGCCGCACAGTCCATCGGCGAGCCGGGCACGCAGCTTACCATGCGTACCTTCCACATCGGCG
GTACGGCATCGCGCGAAATCGAACGTTCGAACATTCAGGCGCAGTACACCGGCCGTGCCGTTCTGTACCGTGTCAAATCC
GTCCGCAACAAAGACGGCCAGCACATGGTCATGGGCAAATCCGGTCAGGTAGGCATTGTGGACGAACAGGGCCGCGAGCG
CGAAAAATACGTACTGCCTTCCGGTGCAAAACTGCACGTGGAAGAAGGACAGGAAGTGAAGAAGGGCCAGCTGCTCGCCG
AGTGGGACCCCTTCAACGAACCGTTCGTTTCGGAAGTGGACGGTCTGGTCAAGTTCACGGACATCATCGAAGGCAAGACC
GTTCAGGAAAAAGCCGACGAAGCAACCCAGATGACCACCCAGACCATTATCGAATACCGTACCACCAACTTCCGGCCGGC
CGTCGCCCTGTGCGATGCCGACGGCGTGGTGAAAACGCGTCCCGAATCGAACATTCCGGCCAGCTATTCGCTGCCGGTGG
GCGCCATTCTGATGGTGCGCGACGGTCAGGAGATCACCGCAGGCGACATCATCGCCCGTAAGCCGCGTGAAAGCTCCAAA
ACCAAGGACATCGTCGGTGGTCTGCCCCGCGTTGCCGAACTCTTTGAAGTGCGCAAGCCCAAAGATATGGCCGTGGTTTC
GCAGATCGACGGCATTGTCACCTTTGCCGGTGAAACCAAGGGTAAACGCAAGCTTGTTGTCACCCCTGAAACCGGTGACG
AGAAAGAATATCTCGTACCCAAGGGCAAGCACATCACCGTCACCGACGGCGACTTTGTGGAAGCAGGCGAAATGCTGACC
GAAGGTCATCCCGAACTCCACGACATTCTGGGCGTCAAGGGCGAAAAATACCTTGCCAACTACCTTGTCGAAGAAATTCA
GGATGTGTACCGCTTCCAGGGCGTCGGCATTGACGACAAGCACATCGAAGTCATCGTGCGCCAGATGCTGAAAAAAGTGA
CCGTGCTCGACCCCGGTCAGACCAGCTTCCTTGTGGGAGAACAGGTCGACAAGGCCGAGTTCCGCATCGAAAACCAGAAA
GCCATCGAGGAAGGCCGCACTCCGGCCACCGCCGAGCCGCTGGTTCTCGGTATCACGCAGGCATCGCTGACCACGTCTTC
GTTCATCTCGGCGGCTTCCTTCCAGGAAACCACCAAGGTGCTTACAGAAGCTTCGCTGCGCGGAAAGAACGACCACCTGC
GCGGCCTGAAGGAAAACGTCATCGTGGGCCGTCTCATTCCCGCCGGCACCGGATACCGCGAGTATGTACACTCCGACATC
TCGGTTCCCGAACAGAAAGAACGCCCCGACAGATTCCTTGAAGAGCTGGTGGGTGCACCCCAGCCCGTTGTGGAAGACTA
A

Upstream 100 bases:

>100_bases
CGGGGCGGCCCGCACAGGGCCGCCCTGTCTGAATACAGGATTTTATCGCGCCAAGCGCGACGAGAAACCCGCTGCAATTC
AACTTTGGTGGGGTAGTAAC

Downstream 100 bases:

>100_bases
CCGTCTTTTCCACCCTGCAGATACCAAAGCCCCCGCTCCGGCGGGGGCTTTTTTTGTGCAGCCGCAAGCCGGCGGTATGC
TTTCAGTTTCAGCCGGACAG

Product: DNA-directed RNA polymerase

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1386; Mature: 1385

Protein sequence:

>1386_residues
MTLDDLFSMRGTAAGQTNIRNLKAMQISIASPESIREWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECNCGKY
KRMKHRGIVCEKCGVEVIASKVRRERMGHIELAAPVAHIWFLKTLPSKIGTLLDMTMADLEKVLYFDSYIVLDPGSTSLA
KLQVISEDQYLQIIDHYGEDALVVGMGAEAIRSLLEELNLEALRAELREESQSTRSQTKKKKLTKRLKIVEAFLESDNKP
EWMVMEVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELGAPDIIIRNEKRMLQESVDALFDNGRRGR
AITGTNGRPLKSLSDMIKGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKLHQCGLPKKMALELFKPFIYSKLEERGLASTI
KSAKKMVEREELVVWDILEEVVREYPILLNRAPTLHRLGIQAFEPLLVEGKAIQLHPLVCAAYNADFDGDQMAVHVPLSV
EAQIECRVLMMSTNNILSPANGTPVIVPSQDIVLGLYYMTVERSFEKGEGMAFCAPWEVVAAYDAGSISLHARIKVRMPD
GRLLNTTPGRIMVGEVLPEGVHFDLVNTVLTKKNIARLVGNAYRDAGTKATVLLCDRLKDIGYEFATRAGVTIGVKDMTI
PQSKKGILADSQAEVDNIERQYRDGIITRTEKYNKVVDVWTKATQDISQEMIKEISYDVMRDEKTGKEELNQSFNPIFMM
SNSGARGNQDQMRQLAGMRGLMAKPSGEIIETPITSCFREGLSVLQYFTSTHGARKGLADTALKTANSGYLTRRLVDVVQ
DVIISEHDCGTVDGLEVGHLIKGGDIKMRLAERVLGRVTLYPVTDPETTEVLFPANTLIDENVAKKLDEAGINSLHIRSA
LTCRSDRGVCAMCYGRDLARGHVVNIGETVGIIAAQSIGEPGTQLTMRTFHIGGTASREIERSNIQAQYTGRAVLYRVKS
VRNKDGQHMVMGKSGQVGIVDEQGREREKYVLPSGAKLHVEEGQEVKKGQLLAEWDPFNEPFVSEVDGLVKFTDIIEGKT
VQEKADEATQMTTQTIIEYRTTNFRPAVALCDADGVVKTRPESNIPASYSLPVGAILMVRDGQEITAGDIIARKPRESSK
TKDIVGGLPRVAELFEVRKPKDMAVVSQIDGIVTFAGETKGKRKLVVTPETGDEKEYLVPKGKHITVTDGDFVEAGEMLT
EGHPELHDILGVKGEKYLANYLVEEIQDVYRFQGVGIDDKHIEVIVRQMLKKVTVLDPGQTSFLVGEQVDKAEFRIENQK
AIEEGRTPATAEPLVLGITQASLTTSSFISAASFQETTKVLTEASLRGKNDHLRGLKENVIVGRLIPAGTGYREYVHSDI
SVPEQKERPDRFLEELVGAPQPVVED

Sequences:

>Translated_1386_residues
MTLDDLFSMRGTAAGQTNIRNLKAMQISIASPESIREWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECNCGKY
KRMKHRGIVCEKCGVEVIASKVRRERMGHIELAAPVAHIWFLKTLPSKIGTLLDMTMADLEKVLYFDSYIVLDPGSTSLA
KLQVISEDQYLQIIDHYGEDALVVGMGAEAIRSLLEELNLEALRAELREESQSTRSQTKKKKLTKRLKIVEAFLESDNKP
EWMVMEVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELGAPDIIIRNEKRMLQESVDALFDNGRRGR
AITGTNGRPLKSLSDMIKGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKLHQCGLPKKMALELFKPFIYSKLEERGLASTI
KSAKKMVEREELVVWDILEEVVREYPILLNRAPTLHRLGIQAFEPLLVEGKAIQLHPLVCAAYNADFDGDQMAVHVPLSV
EAQIECRVLMMSTNNILSPANGTPVIVPSQDIVLGLYYMTVERSFEKGEGMAFCAPWEVVAAYDAGSISLHARIKVRMPD
GRLLNTTPGRIMVGEVLPEGVHFDLVNTVLTKKNIARLVGNAYRDAGTKATVLLCDRLKDIGYEFATRAGVTIGVKDMTI
PQSKKGILADSQAEVDNIERQYRDGIITRTEKYNKVVDVWTKATQDISQEMIKEISYDVMRDEKTGKEELNQSFNPIFMM
SNSGARGNQDQMRQLAGMRGLMAKPSGEIIETPITSCFREGLSVLQYFTSTHGARKGLADTALKTANSGYLTRRLVDVVQ
DVIISEHDCGTVDGLEVGHLIKGGDIKMRLAERVLGRVTLYPVTDPETTEVLFPANTLIDENVAKKLDEAGINSLHIRSA
LTCRSDRGVCAMCYGRDLARGHVVNIGETVGIIAAQSIGEPGTQLTMRTFHIGGTASREIERSNIQAQYTGRAVLYRVKS
VRNKDGQHMVMGKSGQVGIVDEQGREREKYVLPSGAKLHVEEGQEVKKGQLLAEWDPFNEPFVSEVDGLVKFTDIIEGKT
VQEKADEATQMTTQTIIEYRTTNFRPAVALCDADGVVKTRPESNIPASYSLPVGAILMVRDGQEITAGDIIARKPRESSK
TKDIVGGLPRVAELFEVRKPKDMAVVSQIDGIVTFAGETKGKRKLVVTPETGDEKEYLVPKGKHITVTDGDFVEAGEMLT
EGHPELHDILGVKGEKYLANYLVEEIQDVYRFQGVGIDDKHIEVIVRQMLKKVTVLDPGQTSFLVGEQVDKAEFRIENQK
AIEEGRTPATAEPLVLGITQASLTTSSFISAASFQETTKVLTEASLRGKNDHLRGLKENVIVGRLIPAGTGYREYVHSDI
SVPEQKERPDRFLEELVGAPQPVVED
>Mature_1385_residues
TLDDLFSMRGTAAGQTNIRNLKAMQISIASPESIREWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECNCGKYK
RMKHRGIVCEKCGVEVIASKVRRERMGHIELAAPVAHIWFLKTLPSKIGTLLDMTMADLEKVLYFDSYIVLDPGSTSLAK
LQVISEDQYLQIIDHYGEDALVVGMGAEAIRSLLEELNLEALRAELREESQSTRSQTKKKKLTKRLKIVEAFLESDNKPE
WMVMEVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELGAPDIIIRNEKRMLQESVDALFDNGRRGRA
ITGTNGRPLKSLSDMIKGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKLHQCGLPKKMALELFKPFIYSKLEERGLASTIK
SAKKMVEREELVVWDILEEVVREYPILLNRAPTLHRLGIQAFEPLLVEGKAIQLHPLVCAAYNADFDGDQMAVHVPLSVE
AQIECRVLMMSTNNILSPANGTPVIVPSQDIVLGLYYMTVERSFEKGEGMAFCAPWEVVAAYDAGSISLHARIKVRMPDG
RLLNTTPGRIMVGEVLPEGVHFDLVNTVLTKKNIARLVGNAYRDAGTKATVLLCDRLKDIGYEFATRAGVTIGVKDMTIP
QSKKGILADSQAEVDNIERQYRDGIITRTEKYNKVVDVWTKATQDISQEMIKEISYDVMRDEKTGKEELNQSFNPIFMMS
NSGARGNQDQMRQLAGMRGLMAKPSGEIIETPITSCFREGLSVLQYFTSTHGARKGLADTALKTANSGYLTRRLVDVVQD
VIISEHDCGTVDGLEVGHLIKGGDIKMRLAERVLGRVTLYPVTDPETTEVLFPANTLIDENVAKKLDEAGINSLHIRSAL
TCRSDRGVCAMCYGRDLARGHVVNIGETVGIIAAQSIGEPGTQLTMRTFHIGGTASREIERSNIQAQYTGRAVLYRVKSV
RNKDGQHMVMGKSGQVGIVDEQGREREKYVLPSGAKLHVEEGQEVKKGQLLAEWDPFNEPFVSEVDGLVKFTDIIEGKTV
QEKADEATQMTTQTIIEYRTTNFRPAVALCDADGVVKTRPESNIPASYSLPVGAILMVRDGQEITAGDIIARKPRESSKT
KDIVGGLPRVAELFEVRKPKDMAVVSQIDGIVTFAGETKGKRKLVVTPETGDEKEYLVPKGKHITVTDGDFVEAGEMLTE
GHPELHDILGVKGEKYLANYLVEEIQDVYRFQGVGIDDKHIEVIVRQMLKKVTVLDPGQTSFLVGEQVDKAEFRIENQKA
IEEGRTPATAEPLVLGITQASLTTSSFISAASFQETTKVLTEASLRGKNDHLRGLKENVIVGRLIPAGTGYREYVHSDIS
VPEQKERPDRFLEELVGAPQPVVED

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=906, Percent_Identity=25.60706401766, Blast_Score=206, Evalue=1e-52,
Organism=Homo sapiens, GI39725938, Length=841, Percent_Identity=25.5648038049941, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI103471997, Length=259, Percent_Identity=29.3436293436293, Blast_Score=94, Evalue=1e-18,
Organism=Escherichia coli, GI2367335, Length=1390, Percent_Identity=58.8489208633094, Blast_Score=1679, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=909, Percent_Identity=24.972497249725, Blast_Score=182, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI25145495, Length=675, Percent_Identity=25.3333333333333, Blast_Score=172, Evalue=8e-43,
Organism=Saccharomyces cerevisiae, GI6320061, Length=933, Percent_Identity=24.3301178992497, Blast_Score=187, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6324690, Length=690, Percent_Identity=24.0579710144928, Blast_Score=157, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6324917, Length=262, Percent_Identity=27.0992366412214, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360912, Length=837, Percent_Identity=26.6427718040621, Blast_Score=204, Evalue=3e-52,
Organism=Drosophila melanogaster, GI17530899, Length=936, Percent_Identity=25.6410256410256, Blast_Score=186, Evalue=1e-46,
Organism=Drosophila melanogaster, GI17647875, Length=346, Percent_Identity=26.0115606936416, Blast_Score=102, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_DESDG (Q30X04)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_389487.1
- ProteinModelPortal:   Q30X04
- STRING:   Q30X04
- GeneID:   3758796
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2998
- NMPDR:   fig|207559.3.peg.3087
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- ProtClustDB:   PRK00566
- BioCyc:   DDES207559:DDE_2998-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 154099; Mature: 153967

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDDLFSMRGTAAGQTNIRNLKAMQISIASPESIREWSYGEVKKPETINYRTFKPERDG
CCHHHHHHHCCCCCCCCCCCCEEEEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCC
LFCAKIFGPVKDYECNCGKYKRMKHRGIVCEKCGVEVIASKVRRERMGHIELAAPVAHIW
EEEEHHHCCCCCCCCCCCHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCEEEHHHHHHHH
FLKTLPSKIGTLLDMTMADLEKVLYFDSYIVLDPGSTSLAKLQVISEDQYLQIIDHYGED
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEEECCCHHHHHHHHCCCC
ALVVGMGAEAIRSLLEELNLEALRAELREESQSTRSQTKKKKLTKRLKIVEAFLESDNKP
EEEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EWMVMEVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELGAPDIIIRN
CEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEC
EKRMLQESVDALFDNGRRGRAITGTNGRPLKSLSDMIKGKQGRFRQNLLGKRVDYSGRSV
HHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEE
IVVGPKLKLHQCGLPKKMALELFKPFIYSKLEERGLASTIKSAKKMVEREELVVWDILEE
EEECCCEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVREYPILLNRAPTLHRLGIQAFEPLLVEGKAIQLHPLVCAAYNADFDGDQMAVHVPLSV
HHHHCCCEECCCCCHHHHCHHHHCHHHCCCCEEEEEEEEEEEECCCCCCCCEEEEECCEE
EAQIECRVLMMSTNNILSPANGTPVIVPSQDIVLGLYYMTVERSFEKGEGMAFCAPWEVV
EEEEEEEEEEEECCCEECCCCCCEEEECCCCCEEEHHHHHHHHHHHCCCCCEEECCCEEE
AAYDAGSISLHARIKVRMPDGRLLNTTPGRIMVGEVLPEGVHFDLVNTVLTKKNIARLVG
EEECCCCEEEEEEEEEECCCCEEEECCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHHHHH
NAYRDAGTKATVLLCDRLKDIGYEFATRAGVTIGVKDMTIPQSKKGILADSQAEVDNIER
HHHHCCCCCEEEHHHHHHHHCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHH
QYRDGIITRTEKYNKVVDVWTKATQDISQEMIKEISYDVMRDEKTGKEELNQSFNPIFMM
HHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEEE
SNSGARGNQDQMRQLAGMRGLMAKPSGEIIETPITSCFREGLSVLQYFTSTHGARKGLAD
ECCCCCCCHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCHHHCCHHH
TALKTANSGYLTRRLVDVVQDVIISEHDCGTVDGLEVGHLIKGGDIKMRLAERVLGRVTL
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHCCEEE
YPVTDPETTEVLFPANTLIDENVAKKLDEAGINSLHIRSALTCRSDRGVCAMCYGRDLAR
EECCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEHHHHEECCCCCEEEEECCCCCCC
GHVVNIGETVGIIAAQSIGEPGTQLTMRTFHIGGTASREIERSNIQAQYTGRAVLYRVKS
CCEEECCCHHHHEEHHCCCCCCCEEEEEEEEECCCCCHHHHHHCCEEEECCHHHHHHHHH
VRNKDGQHMVMGKSGQVGIVDEQGREREKYVLPSGAKLHVEEGQEVKKGQLLAEWDPFNE
HHCCCCCEEEECCCCCEEEECCCCCCCCCEECCCCCEEEECCCCCCCCCCEEEECCCCCC
PFVSEVDGLVKFTDIIEGKTVQEKADEATQMTTQTIIEYRTTNFRPAVALCDADGVVKTR
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEC
PESNIPASYSLPVGAILMVRDGQEITAGDIIARKPRESSKTKDIVGGLPRVAELFEVRKP
CCCCCCCCCCCCCEEEEEEECCCCCCCCCCEECCCCCCCCHHHHHCCCHHHHHHHHHCCC
KDMAVVSQIDGIVTFAGETKGKRKLVVTPETGDEKEYLVPKGKHITVTDGDFVEAGEMLT
CHHHHHHHHCCEEEECCCCCCCEEEEECCCCCCCCCEECCCCCEEEECCCCHHHHHHHHH
EGHPELHDILGVKGEKYLANYLVEEIQDVYRFQGVGIDDKHIEVIVRQMLKKVTVLDPGQ
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEECCCCC
TSFLVGEQVDKAEFRIENQKAIEEGRTPATAEPLVLGITQASLTTSSFISAASFQETTKV
CEEEECCCCCHHHHEECCHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
LTEASLRGKNDHLRGLKENVIVGRLIPAGTGYREYVHSDISVPEQKERPDRFLEELVGAP
HHHHHCCCCCHHHCCHHHCEEEEEEECCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
QPVVED
CCCCCC
>Mature Secondary Structure 
TLDDLFSMRGTAAGQTNIRNLKAMQISIASPESIREWSYGEVKKPETINYRTFKPERDG
CHHHHHHHCCCCCCCCCCCCEEEEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCC
LFCAKIFGPVKDYECNCGKYKRMKHRGIVCEKCGVEVIASKVRRERMGHIELAAPVAHIW
EEEEHHHCCCCCCCCCCCHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCEEEHHHHHHHH
FLKTLPSKIGTLLDMTMADLEKVLYFDSYIVLDPGSTSLAKLQVISEDQYLQIIDHYGED
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEEECCCHHHHHHHHCCCC
ALVVGMGAEAIRSLLEELNLEALRAELREESQSTRSQTKKKKLTKRLKIVEAFLESDNKP
EEEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EWMVMEVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELGAPDIIIRN
CEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEC
EKRMLQESVDALFDNGRRGRAITGTNGRPLKSLSDMIKGKQGRFRQNLLGKRVDYSGRSV
HHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEE
IVVGPKLKLHQCGLPKKMALELFKPFIYSKLEERGLASTIKSAKKMVEREELVVWDILEE
EEECCCEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVREYPILLNRAPTLHRLGIQAFEPLLVEGKAIQLHPLVCAAYNADFDGDQMAVHVPLSV
HHHHCCCEECCCCCHHHHCHHHHCHHHCCCCEEEEEEEEEEEECCCCCCCCEEEEECCEE
EAQIECRVLMMSTNNILSPANGTPVIVPSQDIVLGLYYMTVERSFEKGEGMAFCAPWEVV
EEEEEEEEEEEECCCEECCCCCCEEEECCCCCEEEHHHHHHHHHHHCCCCCEEECCCEEE
AAYDAGSISLHARIKVRMPDGRLLNTTPGRIMVGEVLPEGVHFDLVNTVLTKKNIARLVG
EEECCCCEEEEEEEEEECCCCEEEECCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHHHHH
NAYRDAGTKATVLLCDRLKDIGYEFATRAGVTIGVKDMTIPQSKKGILADSQAEVDNIER
HHHHCCCCCEEEHHHHHHHHCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHH
QYRDGIITRTEKYNKVVDVWTKATQDISQEMIKEISYDVMRDEKTGKEELNQSFNPIFMM
HHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEEE
SNSGARGNQDQMRQLAGMRGLMAKPSGEIIETPITSCFREGLSVLQYFTSTHGARKGLAD
ECCCCCCCHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCHHHCCHHH
TALKTANSGYLTRRLVDVVQDVIISEHDCGTVDGLEVGHLIKGGDIKMRLAERVLGRVTL
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHCCEEE
YPVTDPETTEVLFPANTLIDENVAKKLDEAGINSLHIRSALTCRSDRGVCAMCYGRDLAR
EECCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEHHHHEECCCCCEEEEECCCCCCC
GHVVNIGETVGIIAAQSIGEPGTQLTMRTFHIGGTASREIERSNIQAQYTGRAVLYRVKS
CCEEECCCHHHHEEHHCCCCCCCEEEEEEEEECCCCCHHHHHHCCEEEECCHHHHHHHHH
VRNKDGQHMVMGKSGQVGIVDEQGREREKYVLPSGAKLHVEEGQEVKKGQLLAEWDPFNE
HHCCCCCEEEECCCCCEEEECCCCCCCCCEECCCCCEEEECCCCCCCCCCEEEECCCCCC
PFVSEVDGLVKFTDIIEGKTVQEKADEATQMTTQTIIEYRTTNFRPAVALCDADGVVKTR
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEC
PESNIPASYSLPVGAILMVRDGQEITAGDIIARKPRESSKTKDIVGGLPRVAELFEVRKP
CCCCCCCCCCCCCEEEEEEECCCCCCCCCCEECCCCCCCCHHHHHCCCHHHHHHHHHCCC
KDMAVVSQIDGIVTFAGETKGKRKLVVTPETGDEKEYLVPKGKHITVTDGDFVEAGEMLT
CHHHHHHHHCCEEEECCCCCCCEEEEECCCCCCCCCEECCCCCEEEECCCCHHHHHHHHH
EGHPELHDILGVKGEKYLANYLVEEIQDVYRFQGVGIDDKHIEVIVRQMLKKVTVLDPGQ
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEECCCCC
TSFLVGEQVDKAEFRIENQKAIEEGRTPATAEPLVLGITQASLTTSSFISAASFQETTKV
CEEEECCCCCHHHHEECCHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
LTEASLRGKNDHLRGLKENVIVGRLIPAGTGYREYVHSDISVPEQKERPDRFLEELVGAP
HHHHHCCCCCHHHCCHHHCEEEEEEECCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
QPVVED
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA