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The map label for this gene is rpoB

Identifier: 78358037

GI number: 78358037

Start: 2974769

End: 2978896

Strand: Direct

Name: rpoB

Synonym: Dde_2997

Alternate gene names: 78358037

Gene position: 2974769-2978896 (Clockwise)

Preceding gene: 78358035

Following gene: 78358038

Centisome position: 79.75

GC content: 58.04

Gene sequence:

>4128_bases
ATGGGCCAGCTCACAAAAAAATTCGGCAAGATCGAAGTCACTCTTCCGATTCCGCACCTGCTCAATCTTCAGGTCGACTC
GTACAAGAAGTTCCTGCAGGAAGGCGCGGCCGCTCTTGCTCCTGACGAGGGGCTTGAGGGTGTGTTCAGATCTGTGTTCC
CCATCGAGGATTTCAACAGAACCGCTAGCCTTGAGTATGTCAGCTACGAAATAGGCGAGCCCAAATACGATCAGGCCGAA
TGCATCTCCAAGGGTCTGACCTATGAGGCTCCTATCCGTATCAAGGTGCGTCTGGTCGTGTACGATGTGGACGAAGACTC
TGAAAACCGCACCATCAGGGACATCAAGGAACAGGATATCTATTTCGGCACTCTGCCGCTGATGACGGAAAAAGGCACCT
TTATCATAAATGGTACCGAGCGTGTCATCGTCAACCAGCTGCAGCGTTCTCCCGGCATCATCTTTGAGCATGACGCCGGC
AAGACCCATTCCAGCCGCAAGGTGCTGTACAGCTGCCGCGTTATTCCCATGCGCGGTTCCTGGCTTGATTTCGACTACGA
CCATAAAGATATACTCTACGTCCGCATCGACCGCCGCCGCAAAATGCCCGCCACCATCCTTTTCAAGGCCATGGGCATGA
GCCGCTCTGACATTCTGGAGTACTTCTACAAAAAAGAATACTACACGCTTGAAGACGACGGCCGTCTGATGTGGGAACTG
GACAAAGACCTGTACCGCAAGGACGTGGCCTATGCCGATGTGGCCGACGGCGAAGGCAAGGTCATCGCCAAGGCCGGCAA
ACCCTACACCAAGCGTTCGTGGCGCCTGATGCTCGAAGCAGGCATTCCCGCGGTTGAAGTCGCCCCCGACTACATCGCAG
GCATGTTTCTGGCCGAAGACATCGTGGACGAAGCAACCGGCGAAGTGCTGGCAGAAGCCGCCGACGAGATCACTCTTGAC
CTCATCGACCGTCTGCGTGAATGCAGCATCAAGCGCGTGCCCGTGCTGCACACCAAAGGCAGCGACACGTCTTCCTCCAT
CCGCGACACCCTGCTGCTCGACAAAACTGCCGATCAGGAACAGGCCCGTGTGGAAATTTACCGCAGACTGCGTCCCAGCT
CGCCCCCCACACCCGAGATTGCCAGCACGTTCTTCGAGAACCTGTTCCGCAATCCCGATTATTACGACCTGTCGCCCGTG
GGACGGTACAAGCTCAACCAGCGTCTGGGTCTGACCACCACGCAGGAACGCGTGCTGACCGATGAAGACATCCTTACCGC
CATCCGTGTGCTCAACCACCTGAAGGACACACACGGCCCTGCGGACGATATCGACCATCTGGGCAACCGCCGCGTGCGTC
CTGTGGGTGAACTGGTGGAAAACCAGTACCGCATCGGCCTTGTGCGCATGGAACGTGCCATCAAGGAACGCATGAGCCTG
CAGGAAGTCTCCACGCTGATGCCGCACGATCTCATCAACCCCAAGCCTGTGCAGGCAGTGCTGAAGGAATTCTTCGGCAC
CTCGCAGCTGTCGCAGTTTATGGACCAGACCAACGCCCTTTCCGAAGTGACGCACAAGCGGCGTCTTTCCGCTCTGGGCC
CCGGCGGTCTTACCCGCGAACGCGCAGGCTTTGAAGTGCGTGACGTGCATACGTCGCACTACGGCCGCATCTGCCCCATT
GAAACTCCTGAAGGTCCGAACATCGGCCTTATCGTTTCGCTGACCACCTATGCCAAGGTGAACGACTTCGGTTTCATCGA
AACCCCGTACCGCGTTGTGCGCGACGGACAGGTGACCGACGAGGTCAAATACCTCGACGCATCCAGCGAACACGGCGAAG
TGGTGGCGCAGGCCAACGCGCGTCTTGATGGCGATCACCGGTTCGTGGACGAATTCGTAACCACCCGTGTGCGTGGCGAC
GTTATCATGTCCCCGCGCGAAGAAGTCACCCTCATGGACATTTCGCCCAGCCAGATGGTTTCCATCTCCGCTGCGCTGAT
TCCGTTCCTTGAGCATGACGACGCCAACCGCGCACTCATGGGCTCCAACATGCAGCGTCAGGCAGTTCCGCTGCTGCGCA
GCACCAAGCCCATCGTGGGTACCGGTATGGAAGCGGACGTGGCCCGCGACTCCGGTGCATGTATCATCGCAGAGGCAGAC
GGTGTCGTGCGCTACGCCGACGCAGACCGCATCGTGGTTTCCTACGAAGGCGACCTGTACCCCAGGACGGGGGGCGTGCG
TTCGTACGACCTGCAGAAATATCACAAGTCCAACCAGAGCTCGTGCTTCGGACAAAAGCCCCTCGTAAGCCGCGGTCAGG
TTATCCGCAAAGGTGACGTGCTGGCTGACGGTCCCGGTATCGAAGACGGCGAACTGGCGCTGGGTAAAAACCTTGTGGTG
GCTTTCATGCCCTGGTGCGGTTACAACTTCGAAGACTCCATCCTCATCTCCGAACGCTGCGTGAAGGAAGATGTCTTCAC
CTCCGTGCACATCGAGGAATTTGAAGTTGTCGCCCGTGACACCAAGCTGGGCCCCGAAGAAATCACCCGCGATATTCCCA
ACGTGGGCGAAGACATGCTGCGCAACCTTGACGGCAGCGGCATTATCCGCATCGGCGCCAATGTAAAGCCCGATGACATT
CTGGTGGGCAAAATCACTCCCAAGGGTGAAACACAGCTTACGCCGGAAGAAAAACTGCTGCGCGCCATCTTCGGTGAAAA
GGCCCGCGACGTGAAAAACACGTCGCTGAAGGTTCCGCCGGGAATCGAGGGTACTGTCATCGACGTCAAGCTGTTCAACC
GCCGTTCCGGCGAAAAGGACGAGCGCACGCGCAACATCGAAGATTACGAGCTGGCACGGCTGGATCAGAAAGAGAAAGAT
CACATCCGCGCACTGACCGAAACCACCCGTGAAAAGCTGGCACCCGTTGTGGTGGGCAAGCAGCTTGCTTACGGACTGGC
CGGGCAGAAAAAAGGCGAAGTCATCGCCGAGGCAGGCCAGACCCTGACCGCGGAAATGCTTGAAGGTCTGCCGGTGAAGA
AGCTCTCCGGCCTCTTCAAGAGCAAAGACACCAACGAGGCCGTACAGCAGGCGCTGGAATCATACGATCGTCAGATCGAG
TTCATCAACGCCATGTACGAATCCAAGCGTGAAAAAGTGACCGAAGGCGACGACCTGCCCCCCGGCGTCATCAAGATGGC
CAAAGTGCACATCGCCGTTAAGCGTAAGCTGAACGTGGGTGACAAAATGGCAGGCCGCCACGGTAACAAGGGTGTCGTAT
CCTGCATACTGCCGCAGGAAGACATGCCCTTCTTCGCCGACGGCCGCCCCGTGGACATCGTGCTCAACCCGCTGGGCGTT
CCCTCCCGTATGAACATCGGGCAGATTATGGAAACGCACCTGGGCTGGGCCGCAAAGGAAATGGGCCGCAAACTGGCGCT
GATGCTGGAACACGGTCAGGATCTTGCGTCCGTGCGCGAACAGGTGAAAACAGTGTTCGCGTCCGATGCCATTTCCTCCG
AGGTGGACAACATGGACGACGAGACCTTTGTCCGGTCCGTGCGCAGACTGCGCGACGGCATTGTGACCAAGACTCCCGTG
TTCGACGGTGCCACCGAAGAGCAAATCTGGAGCTGGATGGAGCAGGCAGGGCTTGCCAACGACGGCAAAACCGAGCTGTA
CGACGGCCGCACCGGTGTCCGGTTCCACAACCGTGTCACCACGGGTGTCATGTACATCCTTAAGCTGCACCACCTTGTTG
ACGAAAAAATCCACGCCCGTTCCACCGGCCCCTACTCGCTTGTCACCCAGCAGCCGCTGGGCGGTAAGGCTCAGTTCGGC
GGCCAGCGTCTGGGTGAAATGGAAGTGTGGGCACTGGAAGCATACGGTGCCGCATATCTGTTGCAGGAATTCCTCACGGT
CAAGTCCGACGACGTGACCGGCCGAGTGAAGATGTACGAAAAGGTCGTGAAGGGTGACAACTTCCTTGAAGCAGGTCTGC
CCGAGTCCTTCAACGTTCTGGTGAAGGAACTCATGTCTCTGGGCCTTGACGTCACCCTGCATCAGGAAGAAGGCAAAAAA
CGCACCAAGCGTGCGGGAATGACCTTCGGCGACGGCACCAGCTACTAG

Upstream 100 bases:

>100_bases
CCTGCCCGCGTCACCGAACATTCCGGGCCTGCCGGGCGTCCCGCTTGCTCGTATCGCGGATTGCCGCTTCCGGAAAAACG
TCTCTTTCTGAGGTGAAAAA

Downstream 100 bases:

>100_bases
CAAATACGGCAACGGGGCGGCCCGCACAGGGCCGCCCTGTCTGAATACAGGATTTTATCGCGCCAAGCGCGACGAGAAAC
CCGCTGCAATTCAACTTTGG

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1375; Mature: 1374

Protein sequence:

>1375_residues
MGQLTKKFGKIEVTLPIPHLLNLQVDSYKKFLQEGAAALAPDEGLEGVFRSVFPIEDFNRTASLEYVSYEIGEPKYDQAE
CISKGLTYEAPIRIKVRLVVYDVDEDSENRTIRDIKEQDIYFGTLPLMTEKGTFIINGTERVIVNQLQRSPGIIFEHDAG
KTHSSRKVLYSCRVIPMRGSWLDFDYDHKDILYVRIDRRRKMPATILFKAMGMSRSDILEYFYKKEYYTLEDDGRLMWEL
DKDLYRKDVAYADVADGEGKVIAKAGKPYTKRSWRLMLEAGIPAVEVAPDYIAGMFLAEDIVDEATGEVLAEAADEITLD
LIDRLRECSIKRVPVLHTKGSDTSSSIRDTLLLDKTADQEQARVEIYRRLRPSSPPTPEIASTFFENLFRNPDYYDLSPV
GRYKLNQRLGLTTTQERVLTDEDILTAIRVLNHLKDTHGPADDIDHLGNRRVRPVGELVENQYRIGLVRMERAIKERMSL
QEVSTLMPHDLINPKPVQAVLKEFFGTSQLSQFMDQTNALSEVTHKRRLSALGPGGLTRERAGFEVRDVHTSHYGRICPI
ETPEGPNIGLIVSLTTYAKVNDFGFIETPYRVVRDGQVTDEVKYLDASSEHGEVVAQANARLDGDHRFVDEFVTTRVRGD
VIMSPREEVTLMDISPSQMVSISAALIPFLEHDDANRALMGSNMQRQAVPLLRSTKPIVGTGMEADVARDSGACIIAEAD
GVVRYADADRIVVSYEGDLYPRTGGVRSYDLQKYHKSNQSSCFGQKPLVSRGQVIRKGDVLADGPGIEDGELALGKNLVV
AFMPWCGYNFEDSILISERCVKEDVFTSVHIEEFEVVARDTKLGPEEITRDIPNVGEDMLRNLDGSGIIRIGANVKPDDI
LVGKITPKGETQLTPEEKLLRAIFGEKARDVKNTSLKVPPGIEGTVIDVKLFNRRSGEKDERTRNIEDYELARLDQKEKD
HIRALTETTREKLAPVVVGKQLAYGLAGQKKGEVIAEAGQTLTAEMLEGLPVKKLSGLFKSKDTNEAVQQALESYDRQIE
FINAMYESKREKVTEGDDLPPGVIKMAKVHIAVKRKLNVGDKMAGRHGNKGVVSCILPQEDMPFFADGRPVDIVLNPLGV
PSRMNIGQIMETHLGWAAKEMGRKLALMLEHGQDLASVREQVKTVFASDAISSEVDNMDDETFVRSVRRLRDGIVTKTPV
FDGATEEQIWSWMEQAGLANDGKTELYDGRTGVRFHNRVTTGVMYILKLHHLVDEKIHARSTGPYSLVTQQPLGGKAQFG
GQRLGEMEVWALEAYGAAYLLQEFLTVKSDDVTGRVKMYEKVVKGDNFLEAGLPESFNVLVKELMSLGLDVTLHQEEGKK
RTKRAGMTFGDGTSY

Sequences:

>Translated_1375_residues
MGQLTKKFGKIEVTLPIPHLLNLQVDSYKKFLQEGAAALAPDEGLEGVFRSVFPIEDFNRTASLEYVSYEIGEPKYDQAE
CISKGLTYEAPIRIKVRLVVYDVDEDSENRTIRDIKEQDIYFGTLPLMTEKGTFIINGTERVIVNQLQRSPGIIFEHDAG
KTHSSRKVLYSCRVIPMRGSWLDFDYDHKDILYVRIDRRRKMPATILFKAMGMSRSDILEYFYKKEYYTLEDDGRLMWEL
DKDLYRKDVAYADVADGEGKVIAKAGKPYTKRSWRLMLEAGIPAVEVAPDYIAGMFLAEDIVDEATGEVLAEAADEITLD
LIDRLRECSIKRVPVLHTKGSDTSSSIRDTLLLDKTADQEQARVEIYRRLRPSSPPTPEIASTFFENLFRNPDYYDLSPV
GRYKLNQRLGLTTTQERVLTDEDILTAIRVLNHLKDTHGPADDIDHLGNRRVRPVGELVENQYRIGLVRMERAIKERMSL
QEVSTLMPHDLINPKPVQAVLKEFFGTSQLSQFMDQTNALSEVTHKRRLSALGPGGLTRERAGFEVRDVHTSHYGRICPI
ETPEGPNIGLIVSLTTYAKVNDFGFIETPYRVVRDGQVTDEVKYLDASSEHGEVVAQANARLDGDHRFVDEFVTTRVRGD
VIMSPREEVTLMDISPSQMVSISAALIPFLEHDDANRALMGSNMQRQAVPLLRSTKPIVGTGMEADVARDSGACIIAEAD
GVVRYADADRIVVSYEGDLYPRTGGVRSYDLQKYHKSNQSSCFGQKPLVSRGQVIRKGDVLADGPGIEDGELALGKNLVV
AFMPWCGYNFEDSILISERCVKEDVFTSVHIEEFEVVARDTKLGPEEITRDIPNVGEDMLRNLDGSGIIRIGANVKPDDI
LVGKITPKGETQLTPEEKLLRAIFGEKARDVKNTSLKVPPGIEGTVIDVKLFNRRSGEKDERTRNIEDYELARLDQKEKD
HIRALTETTREKLAPVVVGKQLAYGLAGQKKGEVIAEAGQTLTAEMLEGLPVKKLSGLFKSKDTNEAVQQALESYDRQIE
FINAMYESKREKVTEGDDLPPGVIKMAKVHIAVKRKLNVGDKMAGRHGNKGVVSCILPQEDMPFFADGRPVDIVLNPLGV
PSRMNIGQIMETHLGWAAKEMGRKLALMLEHGQDLASVREQVKTVFASDAISSEVDNMDDETFVRSVRRLRDGIVTKTPV
FDGATEEQIWSWMEQAGLANDGKTELYDGRTGVRFHNRVTTGVMYILKLHHLVDEKIHARSTGPYSLVTQQPLGGKAQFG
GQRLGEMEVWALEAYGAAYLLQEFLTVKSDDVTGRVKMYEKVVKGDNFLEAGLPESFNVLVKELMSLGLDVTLHQEEGKK
RTKRAGMTFGDGTSY
>Mature_1374_residues
GQLTKKFGKIEVTLPIPHLLNLQVDSYKKFLQEGAAALAPDEGLEGVFRSVFPIEDFNRTASLEYVSYEIGEPKYDQAEC
ISKGLTYEAPIRIKVRLVVYDVDEDSENRTIRDIKEQDIYFGTLPLMTEKGTFIINGTERVIVNQLQRSPGIIFEHDAGK
THSSRKVLYSCRVIPMRGSWLDFDYDHKDILYVRIDRRRKMPATILFKAMGMSRSDILEYFYKKEYYTLEDDGRLMWELD
KDLYRKDVAYADVADGEGKVIAKAGKPYTKRSWRLMLEAGIPAVEVAPDYIAGMFLAEDIVDEATGEVLAEAADEITLDL
IDRLRECSIKRVPVLHTKGSDTSSSIRDTLLLDKTADQEQARVEIYRRLRPSSPPTPEIASTFFENLFRNPDYYDLSPVG
RYKLNQRLGLTTTQERVLTDEDILTAIRVLNHLKDTHGPADDIDHLGNRRVRPVGELVENQYRIGLVRMERAIKERMSLQ
EVSTLMPHDLINPKPVQAVLKEFFGTSQLSQFMDQTNALSEVTHKRRLSALGPGGLTRERAGFEVRDVHTSHYGRICPIE
TPEGPNIGLIVSLTTYAKVNDFGFIETPYRVVRDGQVTDEVKYLDASSEHGEVVAQANARLDGDHRFVDEFVTTRVRGDV
IMSPREEVTLMDISPSQMVSISAALIPFLEHDDANRALMGSNMQRQAVPLLRSTKPIVGTGMEADVARDSGACIIAEADG
VVRYADADRIVVSYEGDLYPRTGGVRSYDLQKYHKSNQSSCFGQKPLVSRGQVIRKGDVLADGPGIEDGELALGKNLVVA
FMPWCGYNFEDSILISERCVKEDVFTSVHIEEFEVVARDTKLGPEEITRDIPNVGEDMLRNLDGSGIIRIGANVKPDDIL
VGKITPKGETQLTPEEKLLRAIFGEKARDVKNTSLKVPPGIEGTVIDVKLFNRRSGEKDERTRNIEDYELARLDQKEKDH
IRALTETTREKLAPVVVGKQLAYGLAGQKKGEVIAEAGQTLTAEMLEGLPVKKLSGLFKSKDTNEAVQQALESYDRQIEF
INAMYESKREKVTEGDDLPPGVIKMAKVHIAVKRKLNVGDKMAGRHGNKGVVSCILPQEDMPFFADGRPVDIVLNPLGVP
SRMNIGQIMETHLGWAAKEMGRKLALMLEHGQDLASVREQVKTVFASDAISSEVDNMDDETFVRSVRRLRDGIVTKTPVF
DGATEEQIWSWMEQAGLANDGKTELYDGRTGVRFHNRVTTGVMYILKLHHLVDEKIHARSTGPYSLVTQQPLGGKAQFGG
QRLGEMEVWALEAYGAAYLLQEFLTVKSDDVTGRVKMYEKVVKGDNFLEAGLPESFNVLVKELMSLGLDVTLHQEEGKKR
TKRAGMTFGDGTSY

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI33469941, Length=276, Percent_Identity=31.8840579710145, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI212286172, Length=276, Percent_Identity=31.8840579710145, Blast_Score=121, Evalue=6e-27,
Organism=Homo sapiens, GI238908505, Length=294, Percent_Identity=29.2517006802721, Blast_Score=120, Evalue=1e-26,
Organism=Homo sapiens, GI238908503, Length=294, Percent_Identity=29.2517006802721, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI4505941, Length=246, Percent_Identity=30.4878048780488, Blast_Score=119, Evalue=2e-26,
Organism=Escherichia coli, GI1790419, Length=1360, Percent_Identity=54.4117647058823, Blast_Score=1458, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=294, Percent_Identity=29.5918367346939, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17552304, Length=246, Percent_Identity=30.4878048780488, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17506623, Length=246, Percent_Identity=29.6747967479675, Blast_Score=114, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6324781, Length=302, Percent_Identity=30.4635761589404, Blast_Score=129, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6324725, Length=313, Percent_Identity=28.1150159744409, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6325267, Length=247, Percent_Identity=31.9838056680162, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17647877, Length=294, Percent_Identity=29.9319727891156, Blast_Score=122, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136444, Length=301, Percent_Identity=27.5747508305648, Blast_Score=120, Evalue=7e-27,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_DESDG (Q30X05)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_389486.1
- ProteinModelPortal:   Q30X05
- STRING:   Q30X05
- GeneID:   3758795
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2997
- NMPDR:   fig|207559.3.peg.3086
- eggNOG:   COG0085
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- ProtClustDB:   PRK00405
- BioCyc:   DDES207559:DDE_2997-MONOMER
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 154039; Mature: 153907

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQLTKKFGKIEVTLPIPHLLNLQVDSYKKFLQEGAAALAPDEGLEGVFRSVFPIEDFNR
CCCCHHHHCCEEEEECCCHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHCCC
TASLEYVSYEIGEPKYDQAECISKGLTYEAPIRIKVRLVVYDVDEDSENRTIRDIKEQDI
CEEEEEEEEECCCCCCCHHHHHHCCCCEECCEEEEEEEEEEECCCCCCCCHHHHHHHCCE
YFGTLPLMTEKGTFIINGTERVIVNQLQRSPGIIFEHDAGKTHSSRKVLYSCRVIPMRGS
EEEECCEEECCCCEEECCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEEEEEECCC
WLDFDYDHKDILYVRIDRRRKMPATILFKAMGMSRSDILEYFYKKEYYTLEDDGRLMWEL
EECCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCEEEEH
DKDLYRKDVAYADVADGEGKVIAKAGKPYTKRSWRLMLEAGIPAVEVAPDYIAGMFLAED
HHHHHHHHCCEEECCCCCCCEEEECCCCCCCCHHEEEEECCCCEEEECHHHHHHHHHHHH
IVDEATGEVLAEAADEITLDLIDRLRECSIKRVPVLHTKGSDTSSSIRDTLLLDKTADQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHEECCCCCHH
QARVEIYRRLRPSSPPTPEIASTFFENLFRNPDYYDLSPVGRYKLNQRLGLTTTQERVLT
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCHHHHHCC
DEDILTAIRVLNHLKDTHGPADDIDHLGNRRVRPVGELVENQYRIGLVRMERAIKERMSL
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHH
QEVSTLMPHDLINPKPVQAVLKEFFGTSQLSQFMDQTNALSEVTHKRRLSALGPGGLTRE
HHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
RAGFEVRDVHTSHYGRICPIETPEGPNIGLIVSLTTYAKVNDFGFIETPYRVVRDGQVTD
HCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHCCCCCCC
EVKYLDASSEHGEVVAQANARLDGDHRFVDEFVTTRVRGDVIMSPREEVTLMDISPSQMV
HHHEECCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCEEECCCCCEEEEECCHHHHH
SISAALIPFLEHDDANRALMGSNMQRQAVPLLRSTKPIVGTGMEADVARDSGACIIAEAD
HHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHCCCCCEECCCCCCCCCCCCCEEEEECC
GVVRYADADRIVVSYEGDLYPRTGGVRSYDLQKYHKSNQSSCFGQKPLVSRGQVIRKGDV
CEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCE
LADGPGIEDGELALGKNLVVAFMPWCGYNFEDSILISERCVKEDVFTSVHIEEFEVVARD
EECCCCCCCCCEECCCCEEEEEECCCCCCCCCCEEHHHHHHHHHHHHHEEHHHHHHHHHC
TKLGPEEITRDIPNVGEDMLRNLDGSGIIRIGANVKPDDILVGKITPKGETQLTPEEKLL
CCCCHHHHHHHCCCHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHH
RAIFGEKARDVKNTSLKVPPGIEGTVIDVKLFNRRSGEKDERTRNIEDYELARLDQKEKD
HHHHCHHHHCCCCCEEECCCCCCCEEEEEEEECCCCCCCHHHHCCCCHHHHHHCCCHHHH
HIRALTETTREKLAPVVVGKQLAYGLAGQKKGEVIAEAGQTLTAEMLEGLPVKKLSGLFK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHCCCCHHHHHHHHC
SKDTNEAVQQALESYDRQIEFINAMYESKREKVTEGDDLPPGVIKMAKVHIAVKRKLNVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEEECCCCCC
DKMAGRHGNKGVVSCILPQEDMPFFADGRPVDIVLNPLGVPSRMNIGQIMETHLGWAAKE
HHHCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
MGRKLALMLEHGQDLASVREQVKTVFASDAISSEVDNMDDETFVRSVRRLRDGIVTKTPV
HHHHEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
FDGATEEQIWSWMEQAGLANDGKTELYDGRTGVRFHNRVTTGVMYILKLHHLVDEKIHAR
CCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCC
STGPYSLVTQQPLGGKAQFGGQRLGEMEVWALEAYGAAYLLQEFLTVKSDDVTGRVKMYE
CCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHH
KVVKGDNFLEAGLPESFNVLVKELMSLGLDVTLHQEEGKKRTKRAGMTFGDGTSY
HHHCCCCCEECCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
GQLTKKFGKIEVTLPIPHLLNLQVDSYKKFLQEGAAALAPDEGLEGVFRSVFPIEDFNR
CCCHHHHCCEEEEECCCHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHCCC
TASLEYVSYEIGEPKYDQAECISKGLTYEAPIRIKVRLVVYDVDEDSENRTIRDIKEQDI
CEEEEEEEEECCCCCCCHHHHHHCCCCEECCEEEEEEEEEEECCCCCCCCHHHHHHHCCE
YFGTLPLMTEKGTFIINGTERVIVNQLQRSPGIIFEHDAGKTHSSRKVLYSCRVIPMRGS
EEEECCEEECCCCEEECCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEEEEEECCC
WLDFDYDHKDILYVRIDRRRKMPATILFKAMGMSRSDILEYFYKKEYYTLEDDGRLMWEL
EECCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCEEEEH
DKDLYRKDVAYADVADGEGKVIAKAGKPYTKRSWRLMLEAGIPAVEVAPDYIAGMFLAED
HHHHHHHHCCEEECCCCCCCEEEECCCCCCCCHHEEEEECCCCEEEECHHHHHHHHHHHH
IVDEATGEVLAEAADEITLDLIDRLRECSIKRVPVLHTKGSDTSSSIRDTLLLDKTADQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHEECCCCCHH
QARVEIYRRLRPSSPPTPEIASTFFENLFRNPDYYDLSPVGRYKLNQRLGLTTTQERVLT
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCHHHHHCC
DEDILTAIRVLNHLKDTHGPADDIDHLGNRRVRPVGELVENQYRIGLVRMERAIKERMSL
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHH
QEVSTLMPHDLINPKPVQAVLKEFFGTSQLSQFMDQTNALSEVTHKRRLSALGPGGLTRE
HHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
RAGFEVRDVHTSHYGRICPIETPEGPNIGLIVSLTTYAKVNDFGFIETPYRVVRDGQVTD
HCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHCCCCCCC
EVKYLDASSEHGEVVAQANARLDGDHRFVDEFVTTRVRGDVIMSPREEVTLMDISPSQMV
HHHEECCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCEEECCCCCEEEEECCHHHHH
SISAALIPFLEHDDANRALMGSNMQRQAVPLLRSTKPIVGTGMEADVARDSGACIIAEAD
HHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHCCCCCEECCCCCCCCCCCCCEEEEECC
GVVRYADADRIVVSYEGDLYPRTGGVRSYDLQKYHKSNQSSCFGQKPLVSRGQVIRKGDV
CEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCE
LADGPGIEDGELALGKNLVVAFMPWCGYNFEDSILISERCVKEDVFTSVHIEEFEVVARD
EECCCCCCCCCEECCCCEEEEEECCCCCCCCCCEEHHHHHHHHHHHHHEEHHHHHHHHHC
TKLGPEEITRDIPNVGEDMLRNLDGSGIIRIGANVKPDDILVGKITPKGETQLTPEEKLL
CCCCHHHHHHHCCCHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHH
RAIFGEKARDVKNTSLKVPPGIEGTVIDVKLFNRRSGEKDERTRNIEDYELARLDQKEKD
HHHHCHHHHCCCCCEEECCCCCCCEEEEEEEECCCCCCCHHHHCCCCHHHHHHCCCHHHH
HIRALTETTREKLAPVVVGKQLAYGLAGQKKGEVIAEAGQTLTAEMLEGLPVKKLSGLFK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHCCCCHHHHHHHHC
SKDTNEAVQQALESYDRQIEFINAMYESKREKVTEGDDLPPGVIKMAKVHIAVKRKLNVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEEECCCCCC
DKMAGRHGNKGVVSCILPQEDMPFFADGRPVDIVLNPLGVPSRMNIGQIMETHLGWAAKE
HHHCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
MGRKLALMLEHGQDLASVREQVKTVFASDAISSEVDNMDDETFVRSVRRLRDGIVTKTPV
HHHHEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
FDGATEEQIWSWMEQAGLANDGKTELYDGRTGVRFHNRVTTGVMYILKLHHLVDEKIHAR
CCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCC
STGPYSLVTQQPLGGKAQFGGQRLGEMEVWALEAYGAAYLLQEFLTVKSDDVTGRVKMYE
CCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHH
KVVKGDNFLEAGLPESFNVLVKELMSLGLDVTLHQEEGKKRTKRAGMTFGDGTSY
HHHCCCCCEECCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA