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The map label for this gene is mtaD [H]

Identifier: 78358003

GI number: 78358003

Start: 2945701

End: 2947107

Strand: Direct

Name: mtaD [H]

Synonym: Dde_2963

Alternate gene names: 78358003

Gene position: 2945701-2947107 (Clockwise)

Preceding gene: 78358001

Following gene: 78358004

Centisome position: 78.97

GC content: 62.69

Gene sequence:

>1407_bases
ATGCCGCAGTGCACGGCTCTGTTTTTCCGCGTTCTGCTGCCCCGCGCTTTACGTCTTTGCCCGCACAGTGTACAAGCTTC
GCGCAACAGCGTACTCTGCTGCGCAGCACATGCCGTCACGATCATCCGCGTCCGGCCTGTCCCTGTCTGCAATCTACGGA
TGAACAAGGCTTTTCCGGTGATGAAACCTACCGCTTTCCGGGCGAAACGCATCATAACCATGACCGAAAAGCGGCTGGCT
GCCGCTGCCGCCACACCGTTTTCATCCGGCATATCTCCGCAATATCAGCAATTTTCAGGTTTTGCTTCAACACCCCGTCC
CGTTTTCGAAGACGGGGTTATTATTGTGCGCGACAACACCATTCTGTGTGTGGAACCCCACAGCCGGTTTGTCCGCCGCG
CGGGCATACCGCTGCACGATCTGGGGCCGGTTACACTGGTTCCCGGCCTGATAAACTGCCACAATCATCTGGAACTGAGT
CATCTGCACGGCAAAACCCTGCTGGGAGAAGGATTCACCAGCTGGGTCGGGCACATGATCCGGCAGGATATGACACCGCA
GGAAGAGGCCGTGCTCAATGCCACGGCATTCATGCACCGCACGGGCACAGTACACGTGGCAGACATCACAAGCCGCGCTC
CGGCGCTGGTGGCACGCTGCGCGCAGCAGGCCGGTCTTTCGTACCACCTGCTGCTTGAATGGTTCGGGCATATGCCGCCC
GCGTCCGGCGCTCCTGCCCTGCCTGATGCGGCAGCACAGCTGCCTCAGGCCGTGCTGCAGGCATGCTGCGCTCCTGCCGG
ACACGCCCTGTATTCCACCCATCCCGAACGGCTGCGGCAGGCAAAAGACTGGTGCCGCGCGCACCACATGCCTTTTTCCA
TGCATCTGGCAGAGCATCAGGGCGAAGTGGAAATGCTGGCTACCGGTACCGGTGCATTCAGGGATCTGCTTTCCGTACGG
GTGCTGCCCGCAGACTACACTCCGCCGCGCTGTTCGCCTGTCAGCCATGCCCACGCGCTGGGGCTGCTGGGTCCGGGTAC
GCTGGCCGTCCACTGCGTGCACTGCGACCGGCACGACATCCAGACCCTTGCCCGCAGCGGCACGGCCGTTTGTCTGTGCC
CGCGCAGCAACAGCGCCATCGGCTCGGGTGATGCCCCTGTAAACAGTTTTATACAGGCCGGACTGCTGCTGTGTCTGGGC
ACGGACAGTCTGGCCTCGAACCATGACCTGAACCTGTGGAATGAGGCCCGCGCGCTGCGCGACCGGCACGGAGCAGCCCC
CGATAATCTGCTGTTCATGCTCACAGCCGGCGGCGCTCAGGCTCTGGGCCTGAACAGACTGGGAGCGCTTGCCCCGGGCA
TGGCCGCCGGATGGGCCGTAGTGCCCGACGACCTCTGCCCCGCCTGA

Upstream 100 bases:

>100_bases
CAGCGGACATGATGAAACACACGCATACTCCGGCGGCAAAAAATAATCTGCAGCCACAGGCATCCGGCAACGGCAAAACC
ATGCGGCATGACACACAAAC

Downstream 100 bases:

>100_bases
GCAGGCACGAACCGGGACATGTATCCCGCAATGAGACCGGAAGACAATGCAAGACCAAGAACGATTCATCTGGCCCCACA
AAGATCTGCTGGACGTCACG

Product: amidohydrolase family protein

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MPQCTALFFRVLLPRALRLCPHSVQASRNSVLCCAAHAVTIIRVRPVPVCNLRMNKAFPVMKPTAFRAKRIITMTEKRLA
AAAATPFSSGISPQYQQFSGFASTPRPVFEDGVIIVRDNTILCVEPHSRFVRRAGIPLHDLGPVTLVPGLINCHNHLELS
HLHGKTLLGEGFTSWVGHMIRQDMTPQEEAVLNATAFMHRTGTVHVADITSRAPALVARCAQQAGLSYHLLLEWFGHMPP
ASGAPALPDAAAQLPQAVLQACCAPAGHALYSTHPERLRQAKDWCRAHHMPFSMHLAEHQGEVEMLATGTGAFRDLLSVR
VLPADYTPPRCSPVSHAHALGLLGPGTLAVHCVHCDRHDIQTLARSGTAVCLCPRSNSAIGSGDAPVNSFIQAGLLLCLG
TDSLASNHDLNLWNEARALRDRHGAAPDNLLFMLTAGGAQALGLNRLGALAPGMAAGWAVVPDDLCPA

Sequences:

>Translated_468_residues
MPQCTALFFRVLLPRALRLCPHSVQASRNSVLCCAAHAVTIIRVRPVPVCNLRMNKAFPVMKPTAFRAKRIITMTEKRLA
AAAATPFSSGISPQYQQFSGFASTPRPVFEDGVIIVRDNTILCVEPHSRFVRRAGIPLHDLGPVTLVPGLINCHNHLELS
HLHGKTLLGEGFTSWVGHMIRQDMTPQEEAVLNATAFMHRTGTVHVADITSRAPALVARCAQQAGLSYHLLLEWFGHMPP
ASGAPALPDAAAQLPQAVLQACCAPAGHALYSTHPERLRQAKDWCRAHHMPFSMHLAEHQGEVEMLATGTGAFRDLLSVR
VLPADYTPPRCSPVSHAHALGLLGPGTLAVHCVHCDRHDIQTLARSGTAVCLCPRSNSAIGSGDAPVNSFIQAGLLLCLG
TDSLASNHDLNLWNEARALRDRHGAAPDNLLFMLTAGGAQALGLNRLGALAPGMAAGWAVVPDDLCPA
>Mature_467_residues
PQCTALFFRVLLPRALRLCPHSVQASRNSVLCCAAHAVTIIRVRPVPVCNLRMNKAFPVMKPTAFRAKRIITMTEKRLAA
AAATPFSSGISPQYQQFSGFASTPRPVFEDGVIIVRDNTILCVEPHSRFVRRAGIPLHDLGPVTLVPGLINCHNHLELSH
LHGKTLLGEGFTSWVGHMIRQDMTPQEEAVLNATAFMHRTGTVHVADITSRAPALVARCAQQAGLSYHLLLEWFGHMPPA
SGAPALPDAAAQLPQAVLQACCAPAGHALYSTHPERLRQAKDWCRAHHMPFSMHLAEHQGEVEMLATGTGAFRDLLSVRV
LPADYTPPRCSPVSHAHALGLLGPGTLAVHCVHCDRHDIQTLARSGTAVCLCPRSNSAIGSGDAPVNSFIQAGLLLCLGT
DSLASNHDLNLWNEARALRDRHGAAPDNLLFMLTAGGAQALGLNRLGALAPGMAAGWAVVPDDLCPA

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 50205; Mature: 50074

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQCTALFFRVLLPRALRLCPHSVQASRNSVLCCAAHAVTIIRVRPVPVCNLRMNKAFPV
CCHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEECEEEEEEECCCCEECEECCCCCCC
MKPTAFRAKRIITMTEKRLAAAAATPFSSGISPQYQQFSGFASTPRPVFEDGVIIVRDNT
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCHHHCCEEEEECCE
ILCVEPHSRFVRRAGIPLHDLGPVTLVPGLINCHNHLELSHLHGKTLLGEGFTSWVGHMI
EEEECCHHHHHHHCCCCCCCCCCHHHHCHHHHCCCCEEEEHHCCCHHHCCCHHHHHHHHH
RQDMTPQEEAVLNATAFMHRTGTVHVADITSRAPALVARCAQQAGLSYHLLLEWFGHMPP
HHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCC
ASGAPALPDAAAQLPQAVLQACCAPAGHALYSTHPERLRQAKDWCRAHHMPFSMHLAEHQ
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHCCCEEEEHHHCC
GEVEMLATGTGAFRDLLSVRVLPADYTPPRCSPVSHAHALGLLGPGTLAVHCVHCDRHDI
CCEEEEEECCHHHHHHHHEEEECCCCCCCCCCCCCHHHHHCCCCCCCEEEEEEECCHHHH
QTLARSGTAVCLCPRSNSAIGSGDAPVNSFIQAGLLLCLGTDSLASNHDLNLWNEARALR
HHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHCEEEEECCCCCCCCCCCCHHHHHHHHH
DRHGAAPDNLLFMLTAGGAQALGLNRLGALAPGMAAGWAVVPDDLCPA
HHCCCCCCCEEEEEECCCCHHCCHHHHHHCCCCCCCCCEECCHHCCCC
>Mature Secondary Structure 
PQCTALFFRVLLPRALRLCPHSVQASRNSVLCCAAHAVTIIRVRPVPVCNLRMNKAFPV
CHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEECEEEEEEECCCCEECEECCCCCCC
MKPTAFRAKRIITMTEKRLAAAAATPFSSGISPQYQQFSGFASTPRPVFEDGVIIVRDNT
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCHHHCCEEEEECCE
ILCVEPHSRFVRRAGIPLHDLGPVTLVPGLINCHNHLELSHLHGKTLLGEGFTSWVGHMI
EEEECCHHHHHHHCCCCCCCCCCHHHHCHHHHCCCCEEEEHHCCCHHHCCCHHHHHHHHH
RQDMTPQEEAVLNATAFMHRTGTVHVADITSRAPALVARCAQQAGLSYHLLLEWFGHMPP
HHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCC
ASGAPALPDAAAQLPQAVLQACCAPAGHALYSTHPERLRQAKDWCRAHHMPFSMHLAEHQ
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHCCCEEEEHHHCC
GEVEMLATGTGAFRDLLSVRVLPADYTPPRCSPVSHAHALGLLGPGTLAVHCVHCDRHDI
CCEEEEEECCHHHHHHHHEEEECCCCCCCCCCCCCHHHHHCCCCCCCEEEEEEECCHHHH
QTLARSGTAVCLCPRSNSAIGSGDAPVNSFIQAGLLLCLGTDSLASNHDLNLWNEARALR
HHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHCEEEEECCCCCCCCCCCCHHHHHHHHH
DRHGAAPDNLLFMLTAGGAQALGLNRLGALAPGMAAGWAVVPDDLCPA
HHCCCCCCCEEEEEECCCCHHCCHHHHHHCCCCCCCCCEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA