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The map label for this gene is comM [H]

Identifier: 78357849

GI number: 78357849

Start: 2796212

End: 2796898

Strand: Reverse

Name: comM [H]

Synonym: Dde_2808

Alternate gene names: 78357849

Gene position: 2796898-2796212 (Counterclockwise)

Preceding gene: 78357850

Following gene: 78357842

Centisome position: 74.98

GC content: 61.28

Gene sequence:

>687_bases
ATGCTTGCCGGAATAGCCAGCGCCGCCCTGCTGGGTGTGGACGCTTTCAGGGTGGATATCGAGATTGATCTTGCCAGACA
GGGTATGCCGTCTTTTTCCATGGTGGGGCTGGCGGAAGGTGCTGTGCGCGAGGCAAAGGAACGTGTTTTTGCCGCGCTGC
GCAATACCGGCCACAAGCTGCCTCCTTCGCGCATAACGGTTAATCTGGCGCCGGCGTCATTGCGCAAAGGCGGCAGTGGA
TATGACCTGCCGCTGGCACTGGGCATGCTGGTGGCAGCCGGTGTGCTGCCTCAGCAGCGTCTGGACGGGTTGTTTGTGGC
AGGTGAACTTTCGCTGACGGGTGAAATAAAACCGGTTACGGGCATTCTGCCGCTGACGCTGCTTGCACGGGATTCCGGAG
CGCGCGGTGTTATCGTGCCGCGGGCCAATGCAGCGGAAGCCGCCGTGGTGGAAGGGCTGGAAGTATGGGGCATGGAGACT
CTGGGCGAGGCTGTGGAGTTTGCGGCGGGGCGGTCCGAGGCGCAGCCCGAACCGTGTTCGGCGTCTGACCTGTGGCGGCG
CGGGGACAGCTGGCATGTGGATTTTGCCGAGGTGAAAGGGCAGGAGCACGCCAAAAGGGCCATCGAAATTGCTGCCGCCG
GTGCGCACAATATGCTCAAAATATATACGCAATACCCCAAGCATTGA

Upstream 100 bases:

>100_bases
GCGGCACAACACCGCAGTTGTTGTCCGCCATAGTTTGGTGTACGTATGAATATCCATATGTTACAGCATTTTGTGTTTTG
CGCGAGGGGTAGAAAAAAGT

Downstream 100 bases:

>100_bases
AAAAGAAGAATAAACATACTTTTCAGACACTTACGCCTATCACTGTCTCCGCAAGTTCTCCTTTACCGCCGTAGCTCATT
TTTCCCAGTCAAAGACTTTC

Product: competence protein ComM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MLAGIASAALLGVDAFRVDIEIDLARQGMPSFSMVGLAEGAVREAKERVFAALRNTGHKLPPSRITVNLAPASLRKGGSG
YDLPLALGMLVAAGVLPQQRLDGLFVAGELSLTGEIKPVTGILPLTLLARDSGARGVIVPRANAAEAAVVEGLEVWGMET
LGEAVEFAAGRSEAQPEPCSASDLWRRGDSWHVDFAEVKGQEHAKRAIEIAAAGAHNMLKIYTQYPKH

Sequences:

>Translated_228_residues
MLAGIASAALLGVDAFRVDIEIDLARQGMPSFSMVGLAEGAVREAKERVFAALRNTGHKLPPSRITVNLAPASLRKGGSG
YDLPLALGMLVAAGVLPQQRLDGLFVAGELSLTGEIKPVTGILPLTLLARDSGARGVIVPRANAAEAAVVEGLEVWGMET
LGEAVEFAAGRSEAQPEPCSASDLWRRGDSWHVDFAEVKGQEHAKRAIEIAAAGAHNMLKIYTQYPKH
>Mature_228_residues
MLAGIASAALLGVDAFRVDIEIDLARQGMPSFSMVGLAEGAVREAKERVFAALRNTGHKLPPSRITVNLAPASLRKGGSG
YDLPLALGMLVAAGVLPQQRLDGLFVAGELSLTGEIKPVTGILPLTLLARDSGARGVIVPRANAAEAAVVEGLEVWGMET
LGEAVEFAAGRSEAQPEPCSASDLWRRGDSWHVDFAEVKGQEHAKRAIEIAAAGAHNMLKIYTQYPKH

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=221, Percent_Identity=37.10407239819, Blast_Score=131, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 24054; Mature: 24054

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAGIASAALLGVDAFRVDIEIDLARQGMPSFSMVGLAEGAVREAKERVFAALRNTGHKL
CCCCHHHHHHHCCEEEEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PPSRITVNLAPASLRKGGSGYDLPLALGMLVAAGVLPQQRLDGLFVAGELSLTGEIKPVT
CCCEEEEEECHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHCCEEEEEEEEECCCCCCCC
GILPLTLLARDSGARGVIVPRANAAEAAVVEGLEVWGMETLGEAVEFAAGRSEAQPEPCS
CHHEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCC
ASDLWRRGDSWHVDFAEVKGQEHAKRAIEIAAAGAHNMLKIYTQYPKH
HHHHHHCCCCCEEEHHHHCCHHHHHHHHHHHHCCCCHHHHHEECCCCC
>Mature Secondary Structure
MLAGIASAALLGVDAFRVDIEIDLARQGMPSFSMVGLAEGAVREAKERVFAALRNTGHKL
CCCCHHHHHHHCCEEEEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PPSRITVNLAPASLRKGGSGYDLPLALGMLVAAGVLPQQRLDGLFVAGELSLTGEIKPVT
CCCEEEEEECHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHCCEEEEEEEEECCCCCCCC
GILPLTLLARDSGARGVIVPRANAAEAAVVEGLEVWGMETLGEAVEFAAGRSEAQPEPCS
CHHEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCC
ASDLWRRGDSWHVDFAEVKGQEHAKRAIEIAAAGAHNMLKIYTQYPKH
HHHHHHCCCCCEEEHHHHCCHHHHHHHHHHHHCCCCHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]