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The map label for this gene is norM [H]

Identifier: 78357693

GI number: 78357693

Start: 2665570

End: 2667057

Strand: Reverse

Name: norM [H]

Synonym: Dde_2651

Alternate gene names: 78357693

Gene position: 2667057-2665570 (Counterclockwise)

Preceding gene: 78357696

Following gene: 78357692

Centisome position: 71.5

GC content: 57.39

Gene sequence:

>1488_bases
ATGTCGTCGGATAGTACCCGAACCATGCAGGCGGCGCGGGCAGGCGCCGCTGCGCCCGAACCGGATTCCGGTTCCGATAC
CGCCATTTTCAGCCTTACATGGCCGCAGATGATGATGATGTTTTTTCATTTCATCATCGGTTTTGTGGATGTGTGGGTGG
CAGGAAAAATCCATCAGGATGTACAGGCATCACTGGGTATCATCACGCAGTGTCTTTTTTTTCTGATGGTGGTGGGTATA
GCCGTGGCCAATGCTTCCGTGGCGGCCATAGGTCAGTCCGCCGGGGCCGGACTGTACAGGCGCGCGCGGCGCTATGTGGC
GCTGGTCATCAAGCTGGGCGTTGTCATGAGTCTGGTTGTGCTGGTCTGCGGCATGCTGTTCAAGGAGCCGTTTCTCAACC
TGCTGCAGGTGCCGGAACGCATCCGCCCCATCACGTCATATTTTTTTGACGTGTATCTGTATGTGCTGCCCATGTACTAC
ATGCTCAACATGACCAATGCCATGTTCCGCGCCCGCAAAATGGTGCTGATTCCTCTGGGCTGCATGATGATTGTCAGTCT
GGTGAACACCGTGGCGGATTTTGGTCTGGGGCTGGGCTGGTGGGGCTTTCCGCAGATGGGCTATGCCGGTGTGGCATGGG
CCACATTCTATTCCATTACGGCCGGTGCGCTGTTCAACATGGTGATGCTGGTCAGAAAAGGCCTGCTGCGGCGCGACTCC
GGCGCTCCGTGGCGCTGGGCCCGCTGTGCGGCACCGTATCTTATCAAGGTGGCGCTTCCGGCAGGCGGCATGCAGATAAT
GTGGCAGACCGGGTATCTGGTATTGTTTGCCATTACCGGCTCGCTGCCTGCGGGCAGCATTGATGCGCTGGCCGGTATGA
CGGCAGGCATGCGCATAGAATCTCTGCTGTTTCTGCCTGCGTTCGCTTTTAATATGACAGCCAGTATTCTGGTCGGGCAT
TTTCTGGGGGCCGGGCGCAAGGCCGAGGCCAAACGCGTGGGGCTGCGTCTTCTGCTGATGGCCTGCGGGTCGTTAACGGT
GGTTGCTGTTTTCATGTGGCCTTTTGTGCCGGAAATCTGCGCTTTTCTGTCGCCGCAACCGGCGGTGCAGGCGCAGGCGG
CCGTGTATCTGAAATATAATCTTGTATCCATTCCCTTCACCGTGGCCAGCATGACGCTGGGCGGTATAATGACCGGCGCC
GGCGCCACGCTGTACACCTTTATTGTGTACAGTTCCGCCACATGGCTGGTGCGGCTGCCGGTGGCCTATGTCATGGGGCA
CCATGTGTGGGGGAACTCCGAAGGTGTGTTTGTAGCCATGCTGATTTCACAGATATTCCAGTCCGGTACCATGCTCTGGC
TGTTCTGGTACCACGACTGGAGCCGTTTCAGCATGATCAAGCGCAACGGCAACAGAAAGAACACCACGGAGACGCCTGCA
GGGGCGGCTCTTGAAGGAGTGAAAAGCAATGTGCGCAGTGGAATTTAA

Upstream 100 bases:

>100_bases
TTTTCCGCTGAGGCATACTTTCAGGCTGTTTTCAGTTAACCGGTGGCAGAATTCTGTGAAATCAGCAGGTTCTGCATTAC
CCTGCAAGGCAGGTTCATAT

Downstream 100 bases:

>100_bases
GCCTTTGACCATGGACGTGATGGAAGAGTATCTGACTCTTTTCTCCGGCACACCGTCGCGGGCTTCTGATTACAGTTTTA
CCAATCTGTGGGGCTGGGCC

Product: MATE efflux family protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSSDSTRTMQAARAGAAAPEPDSGSDTAIFSLTWPQMMMMFFHFIIGFVDVWVAGKIHQDVQASLGIITQCLFFLMVVGI
AVANASVAAIGQSAGAGLYRRARRYVALVIKLGVVMSLVVLVCGMLFKEPFLNLLQVPERIRPITSYFFDVYLYVLPMYY
MLNMTNAMFRARKMVLIPLGCMMIVSLVNTVADFGLGLGWWGFPQMGYAGVAWATFYSITAGALFNMVMLVRKGLLRRDS
GAPWRWARCAAPYLIKVALPAGGMQIMWQTGYLVLFAITGSLPAGSIDALAGMTAGMRIESLLFLPAFAFNMTASILVGH
FLGAGRKAEAKRVGLRLLLMACGSLTVVAVFMWPFVPEICAFLSPQPAVQAQAAVYLKYNLVSIPFTVASMTLGGIMTGA
GATLYTFIVYSSATWLVRLPVAYVMGHHVWGNSEGVFVAMLISQIFQSGTMLWLFWYHDWSRFSMIKRNGNRKNTTETPA
GAALEGVKSNVRSGI

Sequences:

>Translated_495_residues
MSSDSTRTMQAARAGAAAPEPDSGSDTAIFSLTWPQMMMMFFHFIIGFVDVWVAGKIHQDVQASLGIITQCLFFLMVVGI
AVANASVAAIGQSAGAGLYRRARRYVALVIKLGVVMSLVVLVCGMLFKEPFLNLLQVPERIRPITSYFFDVYLYVLPMYY
MLNMTNAMFRARKMVLIPLGCMMIVSLVNTVADFGLGLGWWGFPQMGYAGVAWATFYSITAGALFNMVMLVRKGLLRRDS
GAPWRWARCAAPYLIKVALPAGGMQIMWQTGYLVLFAITGSLPAGSIDALAGMTAGMRIESLLFLPAFAFNMTASILVGH
FLGAGRKAEAKRVGLRLLLMACGSLTVVAVFMWPFVPEICAFLSPQPAVQAQAAVYLKYNLVSIPFTVASMTLGGIMTGA
GATLYTFIVYSSATWLVRLPVAYVMGHHVWGNSEGVFVAMLISQIFQSGTMLWLFWYHDWSRFSMIKRNGNRKNTTETPA
GAALEGVKSNVRSGI
>Mature_494_residues
SSDSTRTMQAARAGAAAPEPDSGSDTAIFSLTWPQMMMMFFHFIIGFVDVWVAGKIHQDVQASLGIITQCLFFLMVVGIA
VANASVAAIGQSAGAGLYRRARRYVALVIKLGVVMSLVVLVCGMLFKEPFLNLLQVPERIRPITSYFFDVYLYVLPMYYM
LNMTNAMFRARKMVLIPLGCMMIVSLVNTVADFGLGLGWWGFPQMGYAGVAWATFYSITAGALFNMVMLVRKGLLRRDSG
APWRWARCAAPYLIKVALPAGGMQIMWQTGYLVLFAITGSLPAGSIDALAGMTAGMRIESLLFLPAFAFNMTASILVGHF
LGAGRKAEAKRVGLRLLLMACGSLTVVAVFMWPFVPEICAFLSPQPAVQAQAAVYLKYNLVSIPFTVASMTLGGIMTGAG
ATLYTFIVYSSATWLVRLPVAYVMGHHVWGNSEGVFVAMLISQIFQSGTMLWLFWYHDWSRFSMIKRNGNRKNTTETPAG
AALEGVKSNVRSGI

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 54100; Mature: 53969

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDSTRTMQAARAGAAAPEPDSGSDTAIFSLTWPQMMMMFFHFIIGFVDVWVAGKIHQD
CCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHH
VQASLGIITQCLFFLMVVGIAVANASVAAIGQSAGAGLYRRARRYVALVIKLGVVMSLVV
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVCGMLFKEPFLNLLQVPERIRPITSYFFDVYLYVLPMYYMLNMTNAMFRARKMVLIPLG
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHH
CMMIVSLVNTVADFGLGLGWWGFPQMGYAGVAWATFYSITAGALFNMVMLVRKGLLRRDS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAPWRWARCAAPYLIKVALPAGGMQIMWQTGYLVLFAITGSLPAGSIDALAGMTAGMRIE
CCCCCHHHHCCCEEEEEEECCCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHCCHHHH
SLLFLPAFAFNMTASILVGHFLGAGRKAEAKRVGLRLLLMACGSLTVVAVFMWPFVPEIC
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
AFLSPQPAVQAQAAVYLKYNLVSIPFTVASMTLGGIMTGAGATLYTFIVYSSATWLVRLP
HHCCCCCCHHHHEEEEEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHH
VAYVMGHHVWGNSEGVFVAMLISQIFQSGTMLWLFWYHDWSRFSMIKRNGNRKNTTETPA
HHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCC
GAALEGVKSNVRSGI
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSDSTRTMQAARAGAAAPEPDSGSDTAIFSLTWPQMMMMFFHFIIGFVDVWVAGKIHQD
CCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHH
VQASLGIITQCLFFLMVVGIAVANASVAAIGQSAGAGLYRRARRYVALVIKLGVVMSLVV
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVCGMLFKEPFLNLLQVPERIRPITSYFFDVYLYVLPMYYMLNMTNAMFRARKMVLIPLG
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHH
CMMIVSLVNTVADFGLGLGWWGFPQMGYAGVAWATFYSITAGALFNMVMLVRKGLLRRDS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAPWRWARCAAPYLIKVALPAGGMQIMWQTGYLVLFAITGSLPAGSIDALAGMTAGMRIE
CCCCCHHHHCCCEEEEEEECCCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHCCHHHH
SLLFLPAFAFNMTASILVGHFLGAGRKAEAKRVGLRLLLMACGSLTVVAVFMWPFVPEIC
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
AFLSPQPAVQAQAAVYLKYNLVSIPFTVASMTLGGIMTGAGATLYTFIVYSSATWLVRLP
HHCCCCCCHHHHEEEEEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHH
VAYVMGHHVWGNSEGVFVAMLISQIFQSGTMLWLFWYHDWSRFSMIKRNGNRKNTTETPA
HHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCC
GAALEGVKSNVRSGI
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]