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The map label for this gene is mdtJ [H]

Identifier: 78357449

GI number: 78357449

Start: 2425675

End: 2426085

Strand: Reverse

Name: mdtJ [H]

Synonym: Dde_2406

Alternate gene names: 78357449

Gene position: 2426085-2425675 (Counterclockwise)

Preceding gene: 78357450

Following gene: 78357448

Centisome position: 65.04

GC content: 60.1

Gene sequence:

>411_bases
ATGTCCGCACCACGTGCGTATCACTGGCTGTGTCTTACCGGCGCGGTCTTTTTCGAGGTGGCCGGTACCACACTGATGAA
GGCTTCACAAAGCTGGAGCATGGCTTTCGGGGCCGAGGCCGGAGTGGTGATCATGCTGCTGTTCATCGGTGTTTCGTATT
ATCTGCTTTCACTTTCCACCACGGCGCTGCCCGTGGGGGTGGCTTTTGCTTTCTGGGAAGGGGTCGGACTTGCATTCATC
ACGCTCGCCAGTGTGTTCATTCTGGGCGAACAGATGAGTCTGCTGCGTTTTGCTGCGCTGTGTGCTGTGCTGGGCGGCGT
GCTGCTGGTGCACCACGGCACTTCTTCCGGCAACCGGCAACAGGCGGAACCCGCCGGTGCGGTTCAGCCGCGCGGAGGGG
AACAGTCATGA

Upstream 100 bases:

>100_bases
GCTGCCGTTGCGCAACCGGTCCTTTTTTCTTTTTCTTTTTCTTTTTTCGTAATTATACATAGAAGCGGTGCTGCGCGCCG
CGTCACGAGGGTATTTTATC

Downstream 100 bases:

>100_bases
CATTTTCGTCGATACTGACAGCAGGACTGCTGCTGGTAATGCTGGCGGCGGCACTGGATGTGGCTGCCAACCTGCTGCTG
GCAAAGTCCCGGGGATTTAC

Product: SMR family multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MSAPRAYHWLCLTGAVFFEVAGTTLMKASQSWSMAFGAEAGVVIMLLFIGVSYYLLSLSTTALPVGVAFAFWEGVGLAFI
TLASVFILGEQMSLLRFAALCAVLGGVLLVHHGTSSGNRQQAEPAGAVQPRGGEQS

Sequences:

>Translated_136_residues
MSAPRAYHWLCLTGAVFFEVAGTTLMKASQSWSMAFGAEAGVVIMLLFIGVSYYLLSLSTTALPVGVAFAFWEGVGLAFI
TLASVFILGEQMSLLRFAALCAVLGGVLLVHHGTSSGNRQQAEPAGAVQPRGGEQS
>Mature_135_residues
SAPRAYHWLCLTGAVFFEVAGTTLMKASQSWSMAFGAEAGVVIMLLFIGVSYYLLSLSTTALPVGVAFAFWEGVGLAFIT
LASVFILGEQMSLLRFAALCAVLGGVLLVHHGTSSGNRQQAEPAGAVQPRGGEQS

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787884, Length=116, Percent_Identity=35.3448275862069, Blast_Score=80, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 14258; Mature: 14127

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPRAYHWLCLTGAVFFEVAGTTLMKASQSWSMAFGAEAGVVIMLLFIGVSYYLLSLST
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHH
TALPVGVAFAFWEGVGLAFITLASVFILGEQMSLLRFAALCAVLGGVLLVHHGTSSGNRQ
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCC
QAEPAGAVQPRGGEQS
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAPRAYHWLCLTGAVFFEVAGTTLMKASQSWSMAFGAEAGVVIMLLFIGVSYYLLSLST
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHH
TALPVGVAFAFWEGVGLAFITLASVFILGEQMSLLRFAALCAVLGGVLLVHHGTSSGNRQ
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCC
QAEPAGAVQPRGGEQS
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA