Click here to switch to the map view.

The map label for this gene is mdtI [H]

Identifier: 78357448

GI number: 78357448

Start: 2425343

End: 2425678

Strand: Reverse

Name: mdtI [H]

Synonym: Dde_2405

Alternate gene names: 78357448

Gene position: 2425678-2425343 (Counterclockwise)

Preceding gene: 78357449

Following gene: 78357445

Centisome position: 65.03

GC content: 61.61

Gene sequence:

>336_bases
ATGACATTTTCGTCGATACTGACAGCAGGACTGCTGCTGGTAATGCTGGCGGCGGCACTGGATGTGGCTGCCAACCTGCT
GCTGGCAAAGTCCCGGGGATTTACCGTGCGCCGGTACGGCGTGATGGCGCTGGCAGCTGTGGGGCTTGCTTTTGTCTGCC
TGTCTTTTGCCGTGCGCAGTATGGATCTGGCCGTTGCCTACGCCATGTGGGGCGGTTTCGGTATTCTGGGGACCTCGCTG
GGCGGCTGGGTGCTGTTCGGGCAGAAAATGGCGCCCAGTGCATGGGCCGGAATTGCCCTGCTTACCTGCGGGCTGGCCAT
GCTGCACATCAGCTGA

Upstream 100 bases:

>100_bases
TGCTGGGCGGCGTGCTGCTGGTGCACCACGGCACTTCTTCCGGCAACCGGCAACAGGCGGAACCCGCCGGTGCGGTTCAG
CCGCGCGGAGGGGAACAGTC

Downstream 100 bases:

>100_bases
TGGTGCAGAACATCCACATGAAATTACGGCGCCATCAGGCGCCGTTTTTGTACAGCATGTCCGCATAGTGCGGTATAAGT
GCCTCCGGCAGCACGGAACG

Product: SMR family multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 111; Mature: 110

Protein sequence:

>111_residues
MTFSSILTAGLLLVMLAAALDVAANLLLAKSRGFTVRRYGVMALAAVGLAFVCLSFAVRSMDLAVAYAMWGGFGILGTSL
GGWVLFGQKMAPSAWAGIALLTCGLAMLHIS

Sequences:

>Translated_111_residues
MTFSSILTAGLLLVMLAAALDVAANLLLAKSRGFTVRRYGVMALAAVGLAFVCLSFAVRSMDLAVAYAMWGGFGILGTSL
GGWVLFGQKMAPSAWAGIALLTCGLAMLHIS
>Mature_110_residues
TFSSILTAGLLLVMLAAALDVAANLLLAKSRGFTVRRYGVMALAAVGLAFVCLSFAVRSMDLAVAYAMWGGFGILGTSLG
GWVLFGQKMAPSAWAGIALLTCGLAMLHIS

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787883, Length=96, Percent_Identity=46.875, Blast_Score=78, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11472; Mature: 11341

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSSILTAGLLLVMLAAALDVAANLLLAKSRGFTVRRYGVMALAAVGLAFVCLSFAVRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MDLAVAYAMWGGFGILGTSLGGWVLFGQKMAPSAWAGIALLTCGLAMLHIS
HHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TFSSILTAGLLLVMLAAALDVAANLLLAKSRGFTVRRYGVMALAAVGLAFVCLSFAVRS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MDLAVAYAMWGGFGILGTSLGGWVLFGQKMAPSAWAGIALLTCGLAMLHIS
HHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA