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The map label for this gene is oxaA

Identifier: 78357437

GI number: 78357437

Start: 2418194

End: 2419804

Strand: Reverse

Name: oxaA

Synonym: Dde_2394

Alternate gene names: 78357437

Gene position: 2419804-2418194 (Counterclockwise)

Preceding gene: 78357438

Following gene: 78357436

Centisome position: 64.87

GC content: 57.29

Gene sequence:

>1611_bases
ATGGAAAACAAGCGTCCGATCATTGCCGTTGTGCTCAGCCTTTTTGTTCTCATTGGCTGGTCTTATCTTTCAGAGTTCAT
GGGCTGGACACCTGCTCCCGCCCCTGTGGAACAAAACGCCACCGCCGTACAGCAGAAGGCTTCCGAGCCTGTAGCGCAGC
CGGTGCAGACCGCTTCCGCCCCTGCCGCATCCTCTTTTGCCCCCACCGAAGGGCGCGAGGTAAAAGTGGACACCCCGCTG
TACACCGCGGTGTTTCAGAGTCAGGGTGGCGTGCTTAAGCATTTCCGGCTGAAAAAGTATACCGAAAGCATCGAAGAAGG
TGCTCCGCTGGTGGAGCTTGTCACGCCGGAAGCCGCCGGAAAGGCCCCCATGGGGCTGCTGCTGAACGGTCAGCCCACGT
GGAAGCTGGCCGCATGGCAGTTTGAAGGCGACGACCTGAAGCTGGACGGTTCCGGCAAAGGCGAGCTGGTCTTTGTAGGT
GAAATGGACGGTGTGCGGTTTGAAAGAACCCTCAGCTTTGATCCGGAAACCTACCTCATCAGCGAAAAGGTGCGTCTGAC
CGATACTGCCGGTGTTTCGCGCGACGTGCGTCTGGGCATGACGCTGAGCACGACCAGCCTGAGCCCCGAGGGCGGCGCTT
ACAATCTGACCCGCATGGCGTGGTATCAGGACGGTTTTCATCAGGAAACATCTGCCGATGATCTGCGCGAAACCGGCGTC
AAGGTTGACGAGGGCGTGAACTGGGGCGGCGTAATGTGCAACTATTTCATGGCTGTCATGGCCCCCGCCGAAGGCGCGCT
GCCTTTCAAGGGCGTGCTGGAAGGCGGTGTGTACCGTTCCGTGGTGGAAAACAGCTCTCTTTCCATAGCGTCCGGTTCCT
CTGCCGAGTTCGGCATCGGCTACTACATTGGTCCCAAGGAAAGCGACAGACTGGCCGCCATGCCTTATCATCTTGATGAG
GCTCTCAACTACGGCTGGTTCACCTTCCTTGCTAAACCGCTGGTTTCCGGTCTGAAGTTCTTCTACTCTTATGCCGGCAA
CTACGGTGTGGCCATCATCATCCTGACCATTCTGGTCAAGCTGCTTTTCTGGCCTCTGTCGCAGAAAAGCTACAAGTCCA
TGGAGCAGATGAAAAAGCTGCAGCCCATGGTGCAGAAAATCAAAGAAAAATACGGGGACGACCGTCAGCGCATGAATCAG
GAAGTCATGGAGCTGTACAAGACCTACAAGGTCAACCCCGCGGGCGGGTGTCTGCCCATGCTGCTTCAGATTCCGGTTTT
TCTGGGTCTGTATCAGGGCCTGCTCAACGCCATCGAGCTGCGTCATGCGCCTTTCATCGCGCATCTGCCTTTTACCGACA
TCGTGTGGCTGGCCGACCTGTCGGCCAAGGACCCCTTCTACATCACCCCTGTTGTGATGGGTGCCACCATGCTGTTGCAG
CAGCGGCTCACTCCTGCGCCCGCCGACCCCACACAGGCGAAGATCATGATGTTCATGCCCGTTGTCTTTACTTTCATGTT
CCTCAACTTCCCCGCAGGGCTTGTGGTGTACTGGCTCGTCAACAACGTGCTTTCCATCGGACAGCAGTGGTGGATGCTCC
GCAAGTCCTAG

Upstream 100 bases:

>100_bases
GCGCATTCTCCGGTGCAATCCTTTGTGCGCCGGTGGCTATGACCCCGTACCAGAATCCCGACATCAAGACGCGAAACGCG
TCAGGAGCTGTTGACGTCTC

Downstream 100 bases:

>100_bases
GCTTCGCCTGACAACTGCGTTTGACTTCGAGGTGAATAAATGGATGAATTCAAGGAGTTTCAGGGCAAAAGTCTGGACGA
CGCCATCAGGGAGGCATGCC

Product: protein translocase subunit yidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MENKRPIIAVVLSLFVLIGWSYLSEFMGWTPAPAPVEQNATAVQQKASEPVAQPVQTASAPAASSFAPTEGREVKVDTPL
YTAVFQSQGGVLKHFRLKKYTESIEEGAPLVELVTPEAAGKAPMGLLLNGQPTWKLAAWQFEGDDLKLDGSGKGELVFVG
EMDGVRFERTLSFDPETYLISEKVRLTDTAGVSRDVRLGMTLSTTSLSPEGGAYNLTRMAWYQDGFHQETSADDLRETGV
KVDEGVNWGGVMCNYFMAVMAPAEGALPFKGVLEGGVYRSVVENSSLSIASGSSAEFGIGYYIGPKESDRLAAMPYHLDE
ALNYGWFTFLAKPLVSGLKFFYSYAGNYGVAIIILTILVKLLFWPLSQKSYKSMEQMKKLQPMVQKIKEKYGDDRQRMNQ
EVMELYKTYKVNPAGGCLPMLLQIPVFLGLYQGLLNAIELRHAPFIAHLPFTDIVWLADLSAKDPFYITPVVMGATMLLQ
QRLTPAPADPTQAKIMMFMPVVFTFMFLNFPAGLVVYWLVNNVLSIGQQWWMLRKS

Sequences:

>Translated_536_residues
MENKRPIIAVVLSLFVLIGWSYLSEFMGWTPAPAPVEQNATAVQQKASEPVAQPVQTASAPAASSFAPTEGREVKVDTPL
YTAVFQSQGGVLKHFRLKKYTESIEEGAPLVELVTPEAAGKAPMGLLLNGQPTWKLAAWQFEGDDLKLDGSGKGELVFVG
EMDGVRFERTLSFDPETYLISEKVRLTDTAGVSRDVRLGMTLSTTSLSPEGGAYNLTRMAWYQDGFHQETSADDLRETGV
KVDEGVNWGGVMCNYFMAVMAPAEGALPFKGVLEGGVYRSVVENSSLSIASGSSAEFGIGYYIGPKESDRLAAMPYHLDE
ALNYGWFTFLAKPLVSGLKFFYSYAGNYGVAIIILTILVKLLFWPLSQKSYKSMEQMKKLQPMVQKIKEKYGDDRQRMNQ
EVMELYKTYKVNPAGGCLPMLLQIPVFLGLYQGLLNAIELRHAPFIAHLPFTDIVWLADLSAKDPFYITPVVMGATMLLQ
QRLTPAPADPTQAKIMMFMPVVFTFMFLNFPAGLVVYWLVNNVLSIGQQWWMLRKS
>Mature_536_residues
MENKRPIIAVVLSLFVLIGWSYLSEFMGWTPAPAPVEQNATAVQQKASEPVAQPVQTASAPAASSFAPTEGREVKVDTPL
YTAVFQSQGGVLKHFRLKKYTESIEEGAPLVELVTPEAAGKAPMGLLLNGQPTWKLAAWQFEGDDLKLDGSGKGELVFVG
EMDGVRFERTLSFDPETYLISEKVRLTDTAGVSRDVRLGMTLSTTSLSPEGGAYNLTRMAWYQDGFHQETSADDLRETGV
KVDEGVNWGGVMCNYFMAVMAPAEGALPFKGVLEGGVYRSVVENSSLSIASGSSAEFGIGYYIGPKESDRLAAMPYHLDE
ALNYGWFTFLAKPLVSGLKFFYSYAGNYGVAIIILTILVKLLFWPLSQKSYKSMEQMKKLQPMVQKIKEKYGDDRQRMNQ
EVMELYKTYKVNPAGGCLPMLLQIPVFLGLYQGLLNAIELRHAPFIAHLPFTDIVWLADLSAKDPFYITPVVMGATMLLQ
QRLTPAPADPTQAKIMMFMPVVFTFMFLNFPAGLVVYWLVNNVLSIGQQWWMLRKS

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=555, Percent_Identity=30.2702702702703, Blast_Score=249, Evalue=3e-67,
Organism=Drosophila melanogaster, GI24662345, Length=192, Percent_Identity=28.125, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356443, Length=192, Percent_Identity=28.125, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_DESDG (Q30YQ5)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388886.1
- ProteinModelPortal:   Q30YQ5
- STRING:   Q30YQ5
- GeneID:   3757410
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2394
- NMPDR:   fig|207559.3.peg.2752
- eggNOG:   COG0706
- HOGENOM:   HBG507812
- OMA:   VMELYKT
- ProtClustDB:   CLSK705047
- BioCyc:   DDES207559:DDE_2394-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 59407; Mature: 59407

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1112a958)-; HASH(0x132c1010)-; HASH(0x12db0ca0)-; HASH(0x1329b318)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKRPIIAVVLSLFVLIGWSYLSEFMGWTPAPAPVEQNATAVQQKASEPVAQPVQTASA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCC
PAASSFAPTEGREVKVDTPLYTAVFQSQGGVLKHFRLKKYTESIEEGAPLVELVTPEAAG
CCCCCCCCCCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
KAPMGLLLNGQPTWKLAAWQFEGDDLKLDGSGKGELVFVGEMDGVRFERTLSFDPETYLI
CCCCEEEECCCCCEEEEEEEECCCEEEECCCCCCCEEEEECCCCCEEEEEECCCCCEEEE
SEKVRLTDTAGVSRDVRLGMTLSTTSLSPEGGAYNLTRMAWYQDGFHQETSADDLRETGV
ECCEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCC
KVDEGVNWGGVMCNYFMAVMAPAEGALPFKGVLEGGVYRSVVENSSLSIASGSSAEFGIG
CCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHCCCCEEEECCCCCCCCEE
YYIGPKESDRLAAMPYHLDEALNYGWFTFLAKPLVSGLKFFYSYAGNYGVAIIILTILVK
EEECCCCCCCEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LLFWPLSQKSYKSMEQMKKLQPMVQKIKEKYGDDRQRMNQEVMELYKTYKVNPAGGCLPM
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHH
LLQIPVFLGLYQGLLNAIELRHAPFIAHLPFTDIVWLADLSAKDPFYITPVVMGATMLLQ
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHEEECCCCCCCEEEHHHHHHHHHHHH
QRLTPAPADPTQAKIMMFMPVVFTFMFLNFPAGLVVYWLVNNVLSIGQQWWMLRKS
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MENKRPIIAVVLSLFVLIGWSYLSEFMGWTPAPAPVEQNATAVQQKASEPVAQPVQTASA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCC
PAASSFAPTEGREVKVDTPLYTAVFQSQGGVLKHFRLKKYTESIEEGAPLVELVTPEAAG
CCCCCCCCCCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
KAPMGLLLNGQPTWKLAAWQFEGDDLKLDGSGKGELVFVGEMDGVRFERTLSFDPETYLI
CCCCEEEECCCCCEEEEEEEECCCEEEECCCCCCCEEEEECCCCCEEEEEECCCCCEEEE
SEKVRLTDTAGVSRDVRLGMTLSTTSLSPEGGAYNLTRMAWYQDGFHQETSADDLRETGV
ECCEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCC
KVDEGVNWGGVMCNYFMAVMAPAEGALPFKGVLEGGVYRSVVENSSLSIASGSSAEFGIG
CCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHCCCCEEEECCCCCCCCEE
YYIGPKESDRLAAMPYHLDEALNYGWFTFLAKPLVSGLKFFYSYAGNYGVAIIILTILVK
EEECCCCCCCEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LLFWPLSQKSYKSMEQMKKLQPMVQKIKEKYGDDRQRMNQEVMELYKTYKVNPAGGCLPM
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHH
LLQIPVFLGLYQGLLNAIELRHAPFIAHLPFTDIVWLADLSAKDPFYITPVVMGATMLLQ
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHEEECCCCCCCEEEHHHHHHHHHHHH
QRLTPAPADPTQAKIMMFMPVVFTFMFLNFPAGLVVYWLVNNVLSIGQQWWMLRKS
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA