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The map label for this gene is 78357380

Identifier: 78357380

GI number: 78357380

Start: 2355836

End: 2357155

Strand: Reverse

Name: 78357380

Synonym: Dde_2337

Alternate gene names: NA

Gene position: 2357155-2355836 (Counterclockwise)

Preceding gene: 78357381

Following gene: 78357379

Centisome position: 63.19

GC content: 56.59

Gene sequence:

>1320_bases
ATGCTTGAAGCCGCCAATAAACTGGGCATCATCTTTTTTCCCGCGTATGACTGGGCCATCAGCCCCACGCATCCCGAGCG
GGAAGAGCGCCTGCTGTACACACAGGACCAGCTGCGTGAAGAGGGACTCTTCGATATTCCCGGCATAACGGAATACAAAC
CGCTGGTGGCCGGCCGCGAAGATGTGGAGCGGGTGCATTTCTGCATTCCCGACATAGAAAGGGTGTGCACAAAATCGCAT
CTTGTCTCTGCGGGCGGGGCCATACAGGCGGCACGCCTGGTGATGGAAGGCAAAGAGGACAAGGCGTTTGCGCTGGTGCG
TCCTCCGGGGCATCACGCCATGAAAGTGGTGCACGGCAACAGAGGGTTTTGCAACGTCAACATTGAAGCCCTGATGATTG
AGCACATACGGGAACATTTCGGCCCGTTGCGGGTGGCTGTCATTGATACCGACTGTCACCACGGCGACGGCACGCAGGAT
ATATACTGGAACGACCCCGACACGCTGTTCATCTCGCTGCATCAGGACGGGCGCACCATTTTTCCCGGAACGGGATTCCC
CGCTGAACTGGGCGGAGTCAATGCGCTCGGTCGCACACTCAACATCCCGCTGCCGCCCAGAACCTCAGACAGAGGGTTCC
TGCATGTCATCGACCATCTGGTGCTGCCGGTGCTGGAGCACTTCAAACCGGATATCGTCATCAACTCCGCCGGACAGGAC
AACCACTTTTCAGACCCCATCACTGACATGCGTTTTTCCGCACAGGGATATGCCGCGCTCAACAGCAGGCTGAACCCTGA
CATCGCTGTGCTGGAGGGCGGCTACGCCATTCAGGGGGCACTGCCGTATGTGAATCTGGGCATTGCGCTGGCCATGGCCG
GACTTGATTACAGCTCTGTACGCGAGCCGGATTTCGACCCTGCCGCCATTGAACAGTCGCCGCGCATCACCGAGTATGTG
GAACGCCTCTGCGAAGAGATGCTCAAGGTTTATTTCAATCCGCCTTCGCAGCCGCGGCAGGGCGAGAAGTCGGGCGACTG
GTGGGTGCGTACAAAAGACATCTTTTACGATACCGACGGCATCAATGAAAGTCAGGTGGAGTCGGTGCGGATATGCCCTG
ATTGTGCGGGCGTGATGAAAATTGAAACATGGTCCACGGCCAATCCCCTCAGTCTTGGTGTGCAGGTACCGCAGAATGCC
TGTGAAAAATGCAGAGGCATCGGCATACGCACCGTTGAGGAGGCGCATGTCAAGGGTAACTACCGCTATATTCAGCTGAT
CAACCGTAAAGACAAGCAGTATGTGCAATATGGTTTTTAA

Upstream 100 bases:

>100_bases
GCGGCCGCTTCGCCCGATGAGGTTTTTGAACAGGTCCGCAGCGCCGTGGCCGATGTGTTTACCATCGGCTGAACTGCTTA
CCGCCACAGGGAGAGTACCC

Downstream 100 bases:

>100_bases
CCGCTTTTTTGCCGGTGCAGGCCGCTCCGGCGCCGCAACCGGCCGGAGTCCGCAAGCAGGTGTGTTTTGTGCTTCCCGTC
GCCTGTGCGGTGGTCTTATG

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MLEAANKLGIIFFPAYDWAISPTHPEREERLLYTQDQLREEGLFDIPGITEYKPLVAGREDVERVHFCIPDIERVCTKSH
LVSAGGAIQAARLVMEGKEDKAFALVRPPGHHAMKVVHGNRGFCNVNIEALMIEHIREHFGPLRVAVIDTDCHHGDGTQD
IYWNDPDTLFISLHQDGRTIFPGTGFPAELGGVNALGRTLNIPLPPRTSDRGFLHVIDHLVLPVLEHFKPDIVINSAGQD
NHFSDPITDMRFSAQGYAALNSRLNPDIAVLEGGYAIQGALPYVNLGIALAMAGLDYSSVREPDFDPAAIEQSPRITEYV
ERLCEEMLKVYFNPPSQPRQGEKSGDWWVRTKDIFYDTDGINESQVESVRICPDCAGVMKIETWSTANPLSLGVQVPQNA
CEKCRGIGIRTVEEAHVKGNYRYIQLINRKDKQYVQYGF

Sequences:

>Translated_439_residues
MLEAANKLGIIFFPAYDWAISPTHPEREERLLYTQDQLREEGLFDIPGITEYKPLVAGREDVERVHFCIPDIERVCTKSH
LVSAGGAIQAARLVMEGKEDKAFALVRPPGHHAMKVVHGNRGFCNVNIEALMIEHIREHFGPLRVAVIDTDCHHGDGTQD
IYWNDPDTLFISLHQDGRTIFPGTGFPAELGGVNALGRTLNIPLPPRTSDRGFLHVIDHLVLPVLEHFKPDIVINSAGQD
NHFSDPITDMRFSAQGYAALNSRLNPDIAVLEGGYAIQGALPYVNLGIALAMAGLDYSSVREPDFDPAAIEQSPRITEYV
ERLCEEMLKVYFNPPSQPRQGEKSGDWWVRTKDIFYDTDGINESQVESVRICPDCAGVMKIETWSTANPLSLGVQVPQNA
CEKCRGIGIRTVEEAHVKGNYRYIQLINRKDKQYVQYGF
>Mature_439_residues
MLEAANKLGIIFFPAYDWAISPTHPEREERLLYTQDQLREEGLFDIPGITEYKPLVAGREDVERVHFCIPDIERVCTKSH
LVSAGGAIQAARLVMEGKEDKAFALVRPPGHHAMKVVHGNRGFCNVNIEALMIEHIREHFGPLRVAVIDTDCHHGDGTQD
IYWNDPDTLFISLHQDGRTIFPGTGFPAELGGVNALGRTLNIPLPPRTSDRGFLHVIDHLVLPVLEHFKPDIVINSAGQD
NHFSDPITDMRFSAQGYAALNSRLNPDIAVLEGGYAIQGALPYVNLGIALAMAGLDYSSVREPDFDPAAIEQSPRITEYV
ERLCEEMLKVYFNPPSQPRQGEKSGDWWVRTKDIFYDTDGINESQVESVRICPDCAGVMKIETWSTANPLSLGVQVPQNA
CEKCRGIGIRTVEEAHVKGNYRYIQLINRKDKQYVQYGF

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=206, Percent_Identity=35.9223300970874, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI30795204, Length=206, Percent_Identity=33.9805825242718, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI30795202, Length=206, Percent_Identity=33.9805825242718, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI17158039, Length=206, Percent_Identity=33.9805825242718, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI153085395, Length=212, Percent_Identity=32.5471698113208, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI20070354, Length=285, Percent_Identity=30.1754385964912, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI62750347, Length=246, Percent_Identity=31.7073170731707, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI62750349, Length=246, Percent_Identity=31.7073170731707, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI148539870, Length=205, Percent_Identity=31.7073170731707, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI169234807, Length=205, Percent_Identity=31.7073170731707, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI13128862, Length=292, Percent_Identity=24.6575342465753, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI226529806, Length=226, Percent_Identity=29.2035398230088, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI13128860, Length=275, Percent_Identity=26.1818181818182, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI8923769, Length=198, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI262073088, Length=135, Percent_Identity=28.1481481481481, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI293336691, Length=180, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193209491, Length=208, Percent_Identity=34.6153846153846, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17540332, Length=301, Percent_Identity=29.2358803986711, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17540334, Length=301, Percent_Identity=29.2358803986711, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI193206283, Length=303, Percent_Identity=29.7029702970297, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25154020, Length=202, Percent_Identity=32.6732673267327, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25154022, Length=202, Percent_Identity=31.1881188118812, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17537347, Length=257, Percent_Identity=27.6264591439689, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534739, Length=202, Percent_Identity=29.2079207920792, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508561, Length=311, Percent_Identity=25.4019292604502, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17561978, Length=200, Percent_Identity=28, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324307, Length=375, Percent_Identity=27.4666666666667, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321244, Length=160, Percent_Identity=30, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323999, Length=204, Percent_Identity=29.9019607843137, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24642142, Length=264, Percent_Identity=31.0606060606061, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24642144, Length=264, Percent_Identity=31.0606060606061, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24642146, Length=264, Percent_Identity=31.0606060606061, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281360899, Length=264, Percent_Identity=31.0606060606061, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641720, Length=171, Percent_Identity=36.2573099415205, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281360801, Length=165, Percent_Identity=36.969696969697, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281360799, Length=165, Percent_Identity=36.969696969697, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24644244, Length=173, Percent_Identity=29.4797687861272, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24657891, Length=275, Percent_Identity=26.9090909090909, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 49117; Mature: 49117

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEAANKLGIIFFPAYDWAISPTHPEREERLLYTQDQLREEGLFDIPGITEYKPLVAGRE
CCCCCCCCEEEEEECCCCEECCCCCCHHHHEEECHHHHHHCCCCCCCCCCCCCCCCCCHH
DVERVHFCIPDIERVCTKSHLVSAGGAIQAARLVMEGKEDKAFALVRPPGHHAMKVVHGN
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECC
RGFCNVNIEALMIEHIREHFGPLRVAVIDTDCHHGDGTQDIYWNDPDTLFISLHQDGRTI
CCEEEEEHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEECCCCEEEEEEECCCCEE
FPGTGFPAELGGVNALGRTLNIPLPPRTSDRGFLHVIDHLVLPVLEHFKPDIVINSAGQD
CCCCCCCHHHCCCHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCC
NHFSDPITDMRFSAQGYAALNSRLNPDIAVLEGGYAIQGALPYVNLGIALAMAGLDYSSV
CCCCCCCHHCEECCCCHHHHHCCCCCCEEEEECCEEEECCCCHHHHHHHHHHHCCCHHHC
REPDFDPAAIEQSPRITEYVERLCEEMLKVYFNPPSQPRQGEKSGDWWVRTKDIFYDTDG
CCCCCCHHHHCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEEEEEEEEECCC
INESQVESVRICPDCAGVMKIETWSTANPLSLGVQVPQNACEKCRGIGIRTVEEAHVKGN
CCHHHHCEEEECCCCCCEEEEEECCCCCCEEEEEECCHHHHHHHHCCCCEEEHHHHHCCC
YRYIQLINRKDKQYVQYGF
EEEEEEECCCCHHHHCCCC
>Mature Secondary Structure
MLEAANKLGIIFFPAYDWAISPTHPEREERLLYTQDQLREEGLFDIPGITEYKPLVAGRE
CCCCCCCCEEEEEECCCCEECCCCCCHHHHEEECHHHHHHCCCCCCCCCCCCCCCCCCHH
DVERVHFCIPDIERVCTKSHLVSAGGAIQAARLVMEGKEDKAFALVRPPGHHAMKVVHGN
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECC
RGFCNVNIEALMIEHIREHFGPLRVAVIDTDCHHGDGTQDIYWNDPDTLFISLHQDGRTI
CCEEEEEHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEECCCCEEEEEEECCCCEE
FPGTGFPAELGGVNALGRTLNIPLPPRTSDRGFLHVIDHLVLPVLEHFKPDIVINSAGQD
CCCCCCCHHHCCCHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCC
NHFSDPITDMRFSAQGYAALNSRLNPDIAVLEGGYAIQGALPYVNLGIALAMAGLDYSSV
CCCCCCCHHCEECCCCHHHHHCCCCCCEEEEECCEEEECCCCHHHHHHHHHHHCCCHHHC
REPDFDPAAIEQSPRITEYVERLCEEMLKVYFNPPSQPRQGEKSGDWWVRTKDIFYDTDG
CCCCCCHHHHCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEEEEEEEEECCC
INESQVESVRICPDCAGVMKIETWSTANPLSLGVQVPQNACEKCRGIGIRTVEEAHVKGN
CCHHHHCEEEECCCCCCEEEEEECCCCCCEEEEEECCHHHHHHHHCCCCEEEHHHHHCCC
YRYIQLINRKDKQYVQYGF
EEEEEEECCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]