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The map label for this gene is ruvB

Identifier: 78357365

GI number: 78357365

Start: 2339783

End: 2340748

Strand: Reverse

Name: ruvB

Synonym: Dde_2322

Alternate gene names: 78357365

Gene position: 2340748-2339783 (Counterclockwise)

Preceding gene: 78357366

Following gene: 78357364

Centisome position: 62.75

GC content: 58.39

Gene sequence:

>966_bases
ATGATGATGGAACAGGAATGTGTTGATGATTCGATCCGCCCGAGAACGCTGGATGATTTTATCGGGCAGGAAGACCTGCG
CGCCAACCTGCGGGTGTATCTGCAGGCGGCCCGGGGCCGCGGGCAGGCCATGGACCATACGCTGTTCTACGGCAACCCCG
GTCTGGGCAAAACAACTCTGGCCCAGATCATGGCCTCCGAGATGGGCGTCAATATGGTGTGCACTTCCGGACCGGTGCTT
GAGCGCAGCGGCGATCTGGCAGCCATTCTGACCAATCTGGGCAAAGGTGATCTGCTTTTTGTGGATGAAATTCACAGAAT
GCCCGTGGCCGTGGAAGAGGTTCTGTATCCGGCCATGGAGGACTTCAAGCTTGATCTGGTCATCGGACAGGGGCCGGGTG
CACGCACCGTCAAGATTGACCTTGAGCCCTTTACTCTGGTAGGAGCCACAACCCGCATCGGACTGCTCTCCTCTCCGCTG
CGCGACCGTTTCGGAATCATCAGCCGGCTTGAATTTTACACTCCGGCGGAGCTGGCCTGCATAGTCAAACGTACGGCAGG
CATAATGGGTGTATCCCTTACAGAAGACGGCGCGGTGGAAATAGGGCGCAGATCGCGGGGCACCCCCCGCATAGCCAACA
GGCTGCTGCGCAGGGTGCGCGATTTCGCTTCGGTGCAGAATTCTGCCGCAGTCACCGCCGCGCTTGCCTCTGACGCTCTG
GCACGCATGGATGTGGACGAGCTGGGGCTGGATCAGATGGACCGCAAGCTGCTTTCGGTGCTTATCGAACACTTTGCAGG
GGGGCCTGTGGGCGTTAAAACGCTTGCCGTGGCCTGTTCCGAAGAGGTTCGCACCATTGAAGATATTTATGAGCCGTATC
TTATCCAGTGCGGCTTTCTTAAACGCACGCCCCGCGGACGCATGGCCACGGCCAAAGCGTATCGCCATATGAATCTGCTT
GCGTAA

Upstream 100 bases:

>100_bases
AAGAAGCCGCCCCCGTGCTGAAAAACATTCTGAAGCAGGATCCCGATCTGGATGTGAGCGAAGCGTTGCGTGCGGCGCTT
AAAGCGCTTGCAAAGGCGAG

Downstream 100 bases:

>100_bases
TAACAAGACCACCCGCCTCCGGGCGGGTGCACTGATTTCCCCCGCGGGAAGCCAGACCGGATGGATGTAGTATGCCCAGT
AAAGAATGCCGAGTGGAGCT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MMMEQECVDDSIRPRTLDDFIGQEDLRANLRVYLQAARGRGQAMDHTLFYGNPGLGKTTLAQIMASEMGVNMVCTSGPVL
ERSGDLAAILTNLGKGDLLFVDEIHRMPVAVEEVLYPAMEDFKLDLVIGQGPGARTVKIDLEPFTLVGATTRIGLLSSPL
RDRFGIISRLEFYTPAELACIVKRTAGIMGVSLTEDGAVEIGRRSRGTPRIANRLLRRVRDFASVQNSAAVTAALASDAL
ARMDVDELGLDQMDRKLLSVLIEHFAGGPVGVKTLAVACSEEVRTIEDIYEPYLIQCGFLKRTPRGRMATAKAYRHMNLL
A

Sequences:

>Translated_321_residues
MMMEQECVDDSIRPRTLDDFIGQEDLRANLRVYLQAARGRGQAMDHTLFYGNPGLGKTTLAQIMASEMGVNMVCTSGPVL
ERSGDLAAILTNLGKGDLLFVDEIHRMPVAVEEVLYPAMEDFKLDLVIGQGPGARTVKIDLEPFTLVGATTRIGLLSSPL
RDRFGIISRLEFYTPAELACIVKRTAGIMGVSLTEDGAVEIGRRSRGTPRIANRLLRRVRDFASVQNSAAVTAALASDAL
ARMDVDELGLDQMDRKLLSVLIEHFAGGPVGVKTLAVACSEEVRTIEDIYEPYLIQCGFLKRTPRGRMATAKAYRHMNLL
A
>Mature_321_residues
MMMEQECVDDSIRPRTLDDFIGQEDLRANLRVYLQAARGRGQAMDHTLFYGNPGLGKTTLAQIMASEMGVNMVCTSGPVL
ERSGDLAAILTNLGKGDLLFVDEIHRMPVAVEEVLYPAMEDFKLDLVIGQGPGARTVKIDLEPFTLVGATTRIGLLSSPL
RDRFGIISRLEFYTPAELACIVKRTAGIMGVSLTEDGAVEIGRRSRGTPRIANRLLRRVRDFASVQNSAAVTAALASDAL
ARMDVDELGLDQMDRKLLSVLIEHFAGGPVGVKTLAVACSEEVRTIEDIYEPYLIQCGFLKRTPRGRMATAKAYRHMNLL
A

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=317, Percent_Identity=58.9905362776025, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_DESDG (Q30YX7)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388814.1
- ProteinModelPortal:   Q30YX7
- SMR:   Q30YX7
- STRING:   Q30YX7
- GeneID:   3757333
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2322
- NMPDR:   fig|207559.3.peg.617
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   DDES207559:DDE_2322-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 35158; Mature: 35158

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMMEQECVDDSIRPRTLDDFIGQEDLRANLRVYLQAARGRGQAMDHTLFYGNPGLGKTTL
CCCCHHHCCCCCCCCCHHHHCCHHHHHHHHHHHEEHHCCCCCCCCCEEEECCCCCCHHHH
AQIMASEMGVNMVCTSGPVLERSGDLAAILTNLGKGDLLFVDEIHRMPVAVEEVLYPAME
HHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHH
DFKLDLVIGQGPGARTVKIDLEPFTLVGATTRIGLLSSPLRDRFGIISRLEFYTPAELAC
CCEEEEEEECCCCCEEEEEECCCEEEECCHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHH
IVKRTAGIMGVSLTEDGAVEIGRRSRGTPRIANRLLRRVRDFASVQNSAAVTAALASDAL
HHHHHCCEEEEEECCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ARMDVDELGLDQMDRKLLSVLIEHFAGGPVGVKTLAVACSEEVRTIEDIYEPYLIQCGFL
HHCCHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
KRTPRGRMATAKAYRHMNLLA
CCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MMMEQECVDDSIRPRTLDDFIGQEDLRANLRVYLQAARGRGQAMDHTLFYGNPGLGKTTL
CCCCHHHCCCCCCCCCHHHHCCHHHHHHHHHHHEEHHCCCCCCCCCEEEECCCCCCHHHH
AQIMASEMGVNMVCTSGPVLERSGDLAAILTNLGKGDLLFVDEIHRMPVAVEEVLYPAME
HHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHH
DFKLDLVIGQGPGARTVKIDLEPFTLVGATTRIGLLSSPLRDRFGIISRLEFYTPAELAC
CCEEEEEEECCCCCEEEEEECCCEEEECCHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHH
IVKRTAGIMGVSLTEDGAVEIGRRSRGTPRIANRLLRRVRDFASVQNSAAVTAALASDAL
HHHHHCCEEEEEECCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ARMDVDELGLDQMDRKLLSVLIEHFAGGPVGVKTLAVACSEEVRTIEDIYEPYLIQCGFL
HHCCHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
KRTPRGRMATAKAYRHMNLLA
CCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA