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The map label for this gene is mlaA [H]

Identifier: 78357344

GI number: 78357344

Start: 2320171

End: 2321019

Strand: Direct

Name: mlaA [H]

Synonym: Dde_2301

Alternate gene names: 78357344

Gene position: 2320171-2321019 (Clockwise)

Preceding gene: 78357343

Following gene: 78357347

Centisome position: 62.2

GC content: 56.07

Gene sequence:

>849_bases
ATGAAAAGGGGAGTTTTTACCGGTCTTGCAGCAATAATGCTGCTTGCCGCGGTCTGCACGGCACAGGCGGCACCGGTATC
ACAGGGGGAACTGGTGACGCCTGAGCGCCTTGAAAAAGCGCAGATGGCTCCCGATGCCCGGGATGCGGCTCTTGCACAGC
AAGAAGAAGAATTTCTGCTTGTTCTCAACAGAGACAATATCGACCCTGAATTCGAAGACTACGGAACAGAGACATCTTCT
GTTCATGTGGCCGACCCCATTGAAGGCTGGAACCGTTTCTGGTTCGGCTTCAATGACTGGTTCTATAATAATCTCGCCGA
TCCGGTCTGGCGCGGGTACGCTTATGTCACCCCCAGCGAACTGAGAACCGGTGCCGACAACTTTTTCCGCAACCTCGCCT
ACCCTGTCCGGTTCATCAACTGCATCCTGCAGGGCAAATTTGTGGCTGCCGGAGTGGAAACATCGCGATTCATTGTCGAC
AGCACCATCGGCGTGGGCGGTCTCATGCAGCCCTCACGCGCCAAGAAGCCCCTTGTAGAACCCGACAGAGAAGACTTCGG
GCAAACCTTGGGATATTGGGGAGTCGGTGAAGGTTTCTACATCGTATGGCCATTTCTGGGACCATCGACGCTGCGAGACA
GCGGCGGTCTGGTGGCCGATGCCGTCACTCACCCGCTGTACTATGTTACGCCCATGTGGCACGGATTTGCTCTGGCAGGG
TACGATCAGCTGAACAAGTTCGGCGGCGTATATGACAACTACATGGCCATCAAGGCACCTGCGCTGGAACCCTACACCGC
CATACGCGATGCGTATATCCAGACGCGGCGAAGCCGCATTGCGCGGTAA

Upstream 100 bases:

>100_bases
CCTGACGAACTTATAACGCGTATCATTGCCAAGGCCGAAGAAGTCGGCAGGGCAAACGGCAACTGATACTGCGTCACCAG
AAACGAGCAAAGAGGCATAT

Downstream 100 bases:

>100_bases
AAAACAGCATCACAGGGGCGCTCAGGCGCCCCTTTTTCATGACCTGTTTTTTTCCGGCCGCGCAACGCGGGCTTGTCCGC
ATGCGCCGTAAACCTGTCTG

Product: surface lipoprotein-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKRGVFTGLAAIMLLAAVCTAQAAPVSQGELVTPERLEKAQMAPDARDAALAQQEEEFLLVLNRDNIDPEFEDYGTETSS
VHVADPIEGWNRFWFGFNDWFYNNLADPVWRGYAYVTPSELRTGADNFFRNLAYPVRFINCILQGKFVAAGVETSRFIVD
STIGVGGLMQPSRAKKPLVEPDREDFGQTLGYWGVGEGFYIVWPFLGPSTLRDSGGLVADAVTHPLYYVTPMWHGFALAG
YDQLNKFGGVYDNYMAIKAPALEPYTAIRDAYIQTRRSRIAR

Sequences:

>Translated_282_residues
MKRGVFTGLAAIMLLAAVCTAQAAPVSQGELVTPERLEKAQMAPDARDAALAQQEEEFLLVLNRDNIDPEFEDYGTETSS
VHVADPIEGWNRFWFGFNDWFYNNLADPVWRGYAYVTPSELRTGADNFFRNLAYPVRFINCILQGKFVAAGVETSRFIVD
STIGVGGLMQPSRAKKPLVEPDREDFGQTLGYWGVGEGFYIVWPFLGPSTLRDSGGLVADAVTHPLYYVTPMWHGFALAG
YDQLNKFGGVYDNYMAIKAPALEPYTAIRDAYIQTRRSRIAR
>Mature_282_residues
MKRGVFTGLAAIMLLAAVCTAQAAPVSQGELVTPERLEKAQMAPDARDAALAQQEEEFLLVLNRDNIDPEFEDYGTETSS
VHVADPIEGWNRFWFGFNDWFYNNLADPVWRGYAYVTPSELRTGADNFFRNLAYPVRFINCILQGKFVAAGVETSRFIVD
STIGVGGLMQPSRAKKPLVEPDREDFGQTLGYWGVGEGFYIVWPFLGPSTLRDSGGLVADAVTHPLYYVTPMWHGFALAG
YDQLNKFGGVYDNYMAIKAPALEPYTAIRDAYIQTRRSRIAR

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=204, Percent_Identity=34.8039215686275, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 31491; Mature: 31491

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRGVFTGLAAIMLLAAVCTAQAAPVSQGELVTPERLEKAQMAPDARDAALAQQEEEFLL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCEEE
VLNRDNIDPEFEDYGTETSSVHVADPIEGWNRFWFGFNDWFYNNLADPVWRGYAYVTPSE
EEECCCCCCCHHHCCCCCCEEEECCCCCCCHHEECCCHHHHHHHCCCHHHCCEEEECHHH
LRTGADNFFRNLAYPVRFINCILQGKFVAAGVETSRFIVDSTIGVGGLMQPSRAKKPLVE
HHCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCCCCCHHCCCCCCC
PDREDFGQTLGYWGVGEGFYIVWPFLGPSTLRDSGGLVADAVTHPLYYVTPMWHGFALAG
CCHHHHHHHCCCCCCCCCCEEEEECCCCHHHCCCCCEEEHHHHCCEEEECCCCCCEEECC
YDQLNKFGGVYDNYMAIKAPALEPYTAIRDAYIQTRRSRIAR
HHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRGVFTGLAAIMLLAAVCTAQAAPVSQGELVTPERLEKAQMAPDARDAALAQQEEEFLL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCEEE
VLNRDNIDPEFEDYGTETSSVHVADPIEGWNRFWFGFNDWFYNNLADPVWRGYAYVTPSE
EEECCCCCCCHHHCCCCCCEEEECCCCCCCHHEECCCHHHHHHHCCCHHHCCEEEECHHH
LRTGADNFFRNLAYPVRFINCILQGKFVAAGVETSRFIVDSTIGVGGLMQPSRAKKPLVE
HHCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCCCCCHHCCCCCCC
PDREDFGQTLGYWGVGEGFYIVWPFLGPSTLRDSGGLVADAVTHPLYYVTPMWHGFALAG
CCHHHHHHHCCCCCCCCCCEEEEECCCCHHHCCCCCEEEHHHHCCEEEECCCCCCEEECC
YDQLNKFGGVYDNYMAIKAPALEPYTAIRDAYIQTRRSRIAR
HHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]