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The map label for this gene is pdxA [H]

Identifier: 78357326

GI number: 78357326

Start: 2304754

End: 2305851

Strand: Reverse

Name: pdxA [H]

Synonym: Dde_2283

Alternate gene names: 78357326

Gene position: 2305851-2304754 (Counterclockwise)

Preceding gene: 78357327

Following gene: 78357325

Centisome position: 61.82

GC content: 62.2

Gene sequence:

>1098_bases
ATGCTTGGAATAAGAAAACAGGATCCTCTGAAGGATGTTGCGGCCGCCCGCTGCCCTTTGCTGGTGACCATGGGCGACGT
CAACGGGCTGGGGCCGGAGCTGGCCTGCCGGGTGCTGGGCGCTGACGGCGGCAGAGGCGCGCTCCGTTACGGAGTCGCGT
CTCCGGTGGTGCTTCTGGGCAGCGGAAAATCTCTGGATACGTTTATGACGCTGTGCGGCATAAACGGCCGGTTCTGGACT
GCGGCCGCTGACAGGCAGCAGCTGGCCGCGCTGCTGGAAAAGGCCCGGCCGGGGCAGGTACTGCTGTACGAACCCCCGGG
GATGGAGACTGTGACTGTGACCCCCGGCAAAGCCACAGCCGACGGCGGGCGCGCTGCCGGACTGGCTCTGCAGGAGGCTT
GCAGCATGCTTAATGACGGAGCTGCCACGGGTGTTGTCACACTGCCGCTTCACAAAGCCATGCTGCAGCAGGCCGGTTTT
GATTTTCCGGGCCATACCGAGTTTCTGGCGCGGCACGCAGGGCTGCGTGATGAAGATGTCTGCATGCACCTGTGCGGTGA
CGTGCTGCGGGTCAGCCTTGTGACCACGCATCCCGCGCTGCGTGATGTTCCCCGCCTTGTGACCCGCCAGCGCGTGGCCC
GCTGCATCGCGCTTACTGTGGAGTTTGTCCGGGCGCTGGGAGCCGGTCACAAACCCGTGGCCGTATGTGGCCTCAACCCG
CACGCCGGTGAATCGGGTAAAATAGGTGTCGAAGACGAAAGCATCATCGCGCCGGCCGTGCGCGAGGCAAAGCGTATGGG
CCTGAATGCCGAAGGTCCGTATCCCGCCGATACGATCTTTTACAGGGCCGCGCAGGGCGAATTTGCCGCGGTGCTGGCCA
TGTACCACGATCAGGGGCTGGCCCCTCTCAAACTGCTGCATTTTTCCGATGCCGTAAATGTGACGCTGGGTCTTCCTTTT
GTCCGTACGTCCGTCGATCATGGAACAGGCTTTGACATAGCAGGCAGAAATACGGCGGACACCGGCAGTTTTGAAAGCGC
ACTGCGTCTTGCGGCGGATATGTGTGCACGGAGGTGCGTCAATGTATCTGGGAATTGA

Upstream 100 bases:

>100_bases
CGCGGCATGCTCCGTTTTATGCGGGCGGGTGTGCTGCCGCACTATCCGGTCGTGCGGGTGCAGTGTGGACAGCAGCGGCG
AAAGGGAATAGTTTTACCGG

Downstream 100 bases:

>100_bases
TGTGGGCGGAACCCATACCGATGCTGTGGTGCTGGATGCACAGAAGCGGATTCAGGCATGGGCCAAGGTGCCCACACTGC
ACCACGACCTGCTGTCTTCC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MLGIRKQDPLKDVAAARCPLLVTMGDVNGLGPELACRVLGADGGRGALRYGVASPVVLLGSGKSLDTFMTLCGINGRFWT
AAADRQQLAALLEKARPGQVLLYEPPGMETVTVTPGKATADGGRAAGLALQEACSMLNDGAATGVVTLPLHKAMLQQAGF
DFPGHTEFLARHAGLRDEDVCMHLCGDVLRVSLVTTHPALRDVPRLVTRQRVARCIALTVEFVRALGAGHKPVAVCGLNP
HAGESGKIGVEDESIIAPAVREAKRMGLNAEGPYPADTIFYRAAQGEFAAVLAMYHDQGLAPLKLLHFSDAVNVTLGLPF
VRTSVDHGTGFDIAGRNTADTGSFESALRLAADMCARRCVNVSGN

Sequences:

>Translated_365_residues
MLGIRKQDPLKDVAAARCPLLVTMGDVNGLGPELACRVLGADGGRGALRYGVASPVVLLGSGKSLDTFMTLCGINGRFWT
AAADRQQLAALLEKARPGQVLLYEPPGMETVTVTPGKATADGGRAAGLALQEACSMLNDGAATGVVTLPLHKAMLQQAGF
DFPGHTEFLARHAGLRDEDVCMHLCGDVLRVSLVTTHPALRDVPRLVTRQRVARCIALTVEFVRALGAGHKPVAVCGLNP
HAGESGKIGVEDESIIAPAVREAKRMGLNAEGPYPADTIFYRAAQGEFAAVLAMYHDQGLAPLKLLHFSDAVNVTLGLPF
VRTSVDHGTGFDIAGRNTADTGSFESALRLAADMCARRCVNVSGN
>Mature_365_residues
MLGIRKQDPLKDVAAARCPLLVTMGDVNGLGPELACRVLGADGGRGALRYGVASPVVLLGSGKSLDTFMTLCGINGRFWT
AAADRQQLAALLEKARPGQVLLYEPPGMETVTVTPGKATADGGRAAGLALQEACSMLNDGAATGVVTLPLHKAMLQQAGF
DFPGHTEFLARHAGLRDEDVCMHLCGDVLRVSLVTTHPALRDVPRLVTRQRVARCIALTVEFVRALGAGHKPVAVCGLNP
HAGESGKIGVEDESIIAPAVREAKRMGLNAEGPYPADTIFYRAAQGEFAAVLAMYHDQGLAPLKLLHFSDAVNVTLGLPF
VRTSVDHGTGFDIAGRNTADTGSFESALRLAADMCARRCVNVSGN

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=244, Percent_Identity=43.0327868852459, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 38356; Mature: 38356

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGIRKQDPLKDVAAARCPLLVTMGDVNGLGPELACRVLGADGGRGALRYGVASPVVLLG
CCCCCCCCCHHHHHHCCCCEEEEECCCCCCCHHHEEEEECCCCCCCCEEECCCCCEEEEE
SGKSLDTFMTLCGINGRFWTAAADRQQLAALLEKARPGQVLLYEPPGMETVTVTPGKATA
CCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCCEEEECCCCCCC
DGGRAAGLALQEACSMLNDGAATGVVTLPLHKAMLQQAGFDFPGHTEFLARHAGLRDEDV
CCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHH
CMHLCGDVLRVSLVTTHPALRDVPRLVTRQRVARCIALTVEFVRALGAGHKPVAVCGLNP
HHHHHHHHHEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
HAGESGKIGVEDESIIAPAVREAKRMGLNAEGPYPADTIFYRAAQGEFAAVLAMYHDQGL
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHEEEECCCCHHHHHHHHHCCCC
APLKLLHFSDAVNVTLGLPFVRTSVDHGTGFDIAGRNTADTGSFESALRLAADMCARRCV
CCEEEEECCCCCEEEECCCHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
NVSGN
CCCCC
>Mature Secondary Structure
MLGIRKQDPLKDVAAARCPLLVTMGDVNGLGPELACRVLGADGGRGALRYGVASPVVLLG
CCCCCCCCCHHHHHHCCCCEEEEECCCCCCCHHHEEEEECCCCCCCCEEECCCCCEEEEE
SGKSLDTFMTLCGINGRFWTAAADRQQLAALLEKARPGQVLLYEPPGMETVTVTPGKATA
CCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCCEEEECCCCCCC
DGGRAAGLALQEACSMLNDGAATGVVTLPLHKAMLQQAGFDFPGHTEFLARHAGLRDEDV
CCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHH
CMHLCGDVLRVSLVTTHPALRDVPRLVTRQRVARCIALTVEFVRALGAGHKPVAVCGLNP
HHHHHHHHHEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
HAGESGKIGVEDESIIAPAVREAKRMGLNAEGPYPADTIFYRAAQGEFAAVLAMYHDQGL
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHEEEECCCCHHHHHHHHHCCCC
APLKLLHFSDAVNVTLGLPFVRTSVDHGTGFDIAGRNTADTGSFESALRLAADMCARRCV
CCEEEEECCCCCEEEECCCHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
NVSGN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA