Click here to switch to the map view.

The map label for this gene is ybiK [C]

Identifier: 78357327

GI number: 78357327

Start: 2305954

End: 2306859

Strand: Reverse

Name: ybiK [C]

Synonym: Dde_2284

Alternate gene names: 78357327

Gene position: 2306859-2305954 (Counterclockwise)

Preceding gene: 78357328

Following gene: 78357326

Centisome position: 61.84

GC content: 61.37

Gene sequence:

>906_bases
ATGAGACCCAGAATAATAGTGCACGGCGGGGCATGGACCATACCCGCGGAGCGGCGGCAGGAACATCTGGACGGTGTGCG
CGCTGCGGTGGAGGCCGCTTGGCCGTTGCTGGAGCAGGGAGCTGATGCGCTTGACGCCGTTCAGGCGGCCGTCAACGTGA
TGGAAGCTGACCCTACGTTTGATGCCGGCCGGGGAGCGGTGCTCAATGCAGACGGCCAGATAGAGCTGGATGCGGCCATA
ATGGACGGTCGTACTTTGAATTATGGCGGAGTAGCCGGAGTGCGGCGTTTTATGACACCGGTCGACATTGCGCGTAAGGT
GCTCGAAACGGAATTCTGCCTGCTGATTGCCGACGGTGCGGAGCGTTTCGCCCGCGAATGCGGGCTGCCGGAGGTTGATC
CCCGCGAGCTGCTGACCGACAGGGAACTGGAGCTGTATCAGAAGCTGTGCAGCCGCGAAGGATACTGCACGCATGACGCC
TTCAAGCCTGTACCGCAGGGTACCGTGGGCGCTGTGGCCATGGATGTGCGGGGCAATATTGCCGCTGCCACGTCCACGGG
GGGGACTCCGTGTAAAAAACCGGGAAGGGTGGGTGATTCTCCGCTGTGCGGAGCAGGCACCTATGCCGACAACGAAACCG
GAGGAGCCTCCGCCACCGGATTCGGTGAAGGAATCATCCGTACGCTGATGACCCGCAGCGCCTGCGACTGTCTGCGCGGG
CATGACGCCATGCAGGCGGCCCGCATGGGCATAGAACTGCTGCACAGGCGTGTGCAGGGCCATGCCGGTCTGATAATGCT
GGATAACCGCGGAGAATATGGTTTTTATCACAACACGGATCATATGGCATTTGCCTATGCCCGCCACGACGGCAGCGTGC
ATGCTTCGGTGCATATGGCGGAATGA

Upstream 100 bases:

>100_bases
GTTGCGGCGTTCCCGTACCTGAGTGTACGGCTGCCTGAAAACGGCTGTACTGTACGCCGTGAACTGCACAACATTTCGTA
CCGATACAGGGGATGTCAGG

Downstream 100 bases:

>100_bases
TTCGCGGCATGCTCCGTTTTATGCGGGCGGGTGTGCTGCCGCACTATCCGGTCGTGCGGGTGCAGTGTGGACAGCAGCGG
CGAAAGGGAATAGTTTTACC

Product: asparaginase

Products: NA

Alternate protein names: L-asparagine amidohydrolase [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MRPRIIVHGGAWTIPAERRQEHLDGVRAAVEAAWPLLEQGADALDAVQAAVNVMEADPTFDAGRGAVLNADGQIELDAAI
MDGRTLNYGGVAGVRRFMTPVDIARKVLETEFCLLIADGAERFARECGLPEVDPRELLTDRELELYQKLCSREGYCTHDA
FKPVPQGTVGAVAMDVRGNIAAATSTGGTPCKKPGRVGDSPLCGAGTYADNETGGASATGFGEGIIRTLMTRSACDCLRG
HDAMQAARMGIELLHRRVQGHAGLIMLDNRGEYGFYHNTDHMAFAYARHDGSVHASVHMAE

Sequences:

>Translated_301_residues
MRPRIIVHGGAWTIPAERRQEHLDGVRAAVEAAWPLLEQGADALDAVQAAVNVMEADPTFDAGRGAVLNADGQIELDAAI
MDGRTLNYGGVAGVRRFMTPVDIARKVLETEFCLLIADGAERFARECGLPEVDPRELLTDRELELYQKLCSREGYCTHDA
FKPVPQGTVGAVAMDVRGNIAAATSTGGTPCKKPGRVGDSPLCGAGTYADNETGGASATGFGEGIIRTLMTRSACDCLRG
HDAMQAARMGIELLHRRVQGHAGLIMLDNRGEYGFYHNTDHMAFAYARHDGSVHASVHMAE
>Mature_301_residues
MRPRIIVHGGAWTIPAERRQEHLDGVRAAVEAAWPLLEQGADALDAVQAAVNVMEADPTFDAGRGAVLNADGQIELDAAI
MDGRTLNYGGVAGVRRFMTPVDIARKVLETEFCLLIADGAERFARECGLPEVDPRELLTDRELELYQKLCSREGYCTHDA
FKPVPQGTVGAVAMDVRGNIAAATSTGGTPCKKPGRVGDSPLCGAGTYADNETGGASATGFGEGIIRTLMTRSACDCLRG
HDAMQAARMGIELLHRRVQGHAGLIMLDNRGEYGFYHNTDHMAFAYARHDGSVHASVHMAE

Specific function: Unknown

COG id: COG1446

COG function: function code E; Asparaginase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ntn-hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI145275202, Length=297, Percent_Identity=40.0673400673401, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI145275200, Length=297, Percent_Identity=40.0673400673401, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI98991769, Length=275, Percent_Identity=33.0909090909091, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI285002251, Length=283, Percent_Identity=33.5689045936396, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI285002253, Length=283, Percent_Identity=31.8021201413428, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1787050, Length=303, Percent_Identity=39.9339933993399, Blast_Score=166, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI32564649, Length=282, Percent_Identity=23.4042553191489, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI18921183, Length=319, Percent_Identity=35.7366771159875, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI21357893, Length=339, Percent_Identity=30.3834808259587, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI221330102, Length=290, Percent_Identity=33.448275862069, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24652135, Length=290, Percent_Identity=33.448275862069, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24657358, Length=281, Percent_Identity=29.5373665480427, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24655553, Length=265, Percent_Identity=29.811320754717, Blast_Score=88, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000246 [H]

Pfam domain/function: PF01112 Asparaginase_2 [H]

EC number: =3.5.1.1 [H]

Molecular weight: Translated: 32275; Mature: 32275

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPRIIVHGGAWTIPAERRQEHLDGVRAAVEAAWPLLEQGADALDAVQAAVNVMEADPTF
CCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
DAGRGAVLNADGQIELDAAIMDGRTLNYGGVAGVRRFMTPVDIARKVLETEFCLLIADGA
CCCCCCEECCCCCEEEEEEEECCCEECCCCHHHHHHHCCHHHHHHHHHHHHEEEEEECCH
ERFARECGLPEVDPRELLTDRELELYQKLCSREGYCTHDAFKPVPQGTVGAVAMDVRGNI
HHHHHHCCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCHHCCCCCCCCCCEEEEECCCCE
AAATSTGGTPCKKPGRVGDSPLCGAGTYADNETGGASATGFGEGIIRTLMTRSACDCLRG
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
HDAMQAARMGIELLHRRVQGHAGLIMLDNRGEYGFYHNTDHMAFAYARHDGSVHASVHMA
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCEEEEEEECCCCEEEEEEEC
E
C
>Mature Secondary Structure
MRPRIIVHGGAWTIPAERRQEHLDGVRAAVEAAWPLLEQGADALDAVQAAVNVMEADPTF
CCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
DAGRGAVLNADGQIELDAAIMDGRTLNYGGVAGVRRFMTPVDIARKVLETEFCLLIADGA
CCCCCCEECCCCCEEEEEEEECCCEECCCCHHHHHHHCCHHHHHHHHHHHHEEEEEECCH
ERFARECGLPEVDPRELLTDRELELYQKLCSREGYCTHDAFKPVPQGTVGAVAMDVRGNI
HHHHHHCCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCHHCCCCCCCCCCEEEEECCCCE
AAATSTGGTPCKKPGRVGDSPLCGAGTYADNETGGASATGFGEGIIRTLMTRSACDCLRG
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
HDAMQAARMGIELLHRRVQGHAGLIMLDNRGEYGFYHNTDHMAFAYARHDGSVHASVHMA
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCEEEEEEECCCCEEEEEEEC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]