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The map label for this gene is hyuA [H]

Identifier: 78357325

GI number: 78357325

Start: 2303118

End: 2304770

Strand: Reverse

Name: hyuA [H]

Synonym: Dde_2282

Alternate gene names: 78357325

Gene position: 2304770-2303118 (Counterclockwise)

Preceding gene: 78357326

Following gene: 78357324

Centisome position: 61.79

GC content: 58.08

Gene sequence:

>1653_bases
ATGTATCTGGGAATTGATGTGGGCGGAACCCATACCGATGCTGTGGTGCTGGATGCACAGAAGCGGATTCAGGCATGGGC
CAAGGTGCCCACACTGCACCACGACCTGCTGTCTTCCGTCACACAGGCGCTTGACAGTGTTCTGCAGTCAGTTGCGGCGC
AGGATATAGTACGGCTGAATCTGAGCACCACGCTGTCTACCAATGCCATTGTGGAAAGCAAGACCGAGGATGTCGGAGTG
CTTGTTTCGTCCGGTCCGGGCATTGATCCTGAAAATTTCCGGCAGGGCGGATTCTTTTTTCCTCTTTCCGGTTCCATCGA
CCACCGCGGTAAAGTAATAGCCGCCATGGAGCAGGACGAACTGGCCGCTGCGGTGCGCCGGTGCTGCGATTCCGGCATAC
GTGTCTATGCGGCGGTGGGTAAATTTTCCACGCGTAACCCCGATCATGAAGAAACCATGGCGCATGAAGCCATGCAGTGC
GGCGACTTTGTATCCATGGGACACCGGCTTTCAGGTCAGCTCAGTTTTCCGCGCAGGGTGGCAACTGCGTATTACAATTC
AGCTGTGTGGCGGCTTTACAACAGCTTTGCCGATGCCGTGGAGTCTTCTGCCCGTGCCAAGGGCGTAACCGCGCCTGTGC
ATATTCTCAAAGCCGACGGCGGCACCATGCCGCTGGCTGTTTCACGGCGTATGCCCGTCGAGTCCATTCTTTCAGGCCCT
GCGGCCAGCGTTATGGGCATTGTGGCTCTTTACGATATCAGAGAAGACGCTGTGATTCTGGATATCGGCGGGACAACGAC
AGATATTGCGCTTTTTGCCTCCGGTTCTCCGGTTATCGAAAATGACGGTATCTCTGTCGGCAGTTATCCTACATTGGTCA
GGGCGCTGCGTACGCTTTCCATAGGCGTGGGCGGTGATTCTCGCCTGCGCATTGCCGCGGGTGCTGTGCGGGTGGGGCCG
GACAGGTCCGGACCCTGTGTTGCCAACGGCGGAACACATGTGGCGCTGATGGATGCCATGAATTATCTGGAAGTGGCTGC
CGTGGGCGACGTGGAAGCCTCGCGCGAGGCTGTGCGGCAGCTGGCCTCTCTGTGGGACATGTATCCGGAAAAACTGGCCC
GCGAAGCGCTGGACACAGCGGTAAACACCATCTGCGCCGCCGTGGACAGGTTGCTTGACGAAGTCAATGCGCAGCCTGTG
TATACCATCATCGAACTGCTTGACGGTGTGAAGCTGAATCCCGGCAGGGTGTTTGTGATGGGAGGTCCCGCCGCCGCGTT
TGCCCCGCTTTTGCGTAATGTCATGAACAGGCGCATAGATGTACCCCGTGACCATGCGGTGGCCAACGCCGTGGGGGCTG
CGCTCACACGCACCACGGCTGAGCTGGAGCTTTTTGCCGATACTGAAAAGGGCCTTGTTTTTGTGCCCACGCTCGGGCTG
CGCCGCGAGGCACCGCTGGGATACAATCTGGATGACGCTGTGGCCGATGCCGGCAGGTACCTGACGGAATCACTGGCCGG
CATGGGAATACATATCCGTCCGGAAGATGTGGATGTCCTTGAGGCCGGTTCTTTCAACATGGTGGATATGTACGGCGGCA
AGGGCCGTAATATCCGTGTGAAGTGTCAGGTACGGCCCGGCATTTCGCTTTGA

Upstream 100 bases:

>100_bases
GGAACAGGCTTTGACATAGCAGGCAGAAATACGGCGGACACCGGCAGTTTTGAAAGCGCACTGCGTCTTGCGGCGGATAT
GTGTGCACGGAGGTGCGTCA

Downstream 100 bases:

>100_bases
TGCACCGCGGGTCTCATATGGCCTTTGTATTCACGGGGCGCGTTCCGGCAACGGGGCGCGCCTTTTGCGTGTAAAAGCGA
CCGCCGCAGTGTTTCAATAT

Product: hydantoinase/oxoprolinase family protein

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MYLGIDVGGTHTDAVVLDAQKRIQAWAKVPTLHHDLLSSVTQALDSVLQSVAAQDIVRLNLSTTLSTNAIVESKTEDVGV
LVSSGPGIDPENFRQGGFFFPLSGSIDHRGKVIAAMEQDELAAAVRRCCDSGIRVYAAVGKFSTRNPDHEETMAHEAMQC
GDFVSMGHRLSGQLSFPRRVATAYYNSAVWRLYNSFADAVESSARAKGVTAPVHILKADGGTMPLAVSRRMPVESILSGP
AASVMGIVALYDIREDAVILDIGGTTTDIALFASGSPVIENDGISVGSYPTLVRALRTLSIGVGGDSRLRIAAGAVRVGP
DRSGPCVANGGTHVALMDAMNYLEVAAVGDVEASREAVRQLASLWDMYPEKLAREALDTAVNTICAAVDRLLDEVNAQPV
YTIIELLDGVKLNPGRVFVMGGPAAAFAPLLRNVMNRRIDVPRDHAVANAVGAALTRTTAELELFADTEKGLVFVPTLGL
RREAPLGYNLDDAVADAGRYLTESLAGMGIHIRPEDVDVLEAGSFNMVDMYGGKGRNIRVKCQVRPGISL

Sequences:

>Translated_550_residues
MYLGIDVGGTHTDAVVLDAQKRIQAWAKVPTLHHDLLSSVTQALDSVLQSVAAQDIVRLNLSTTLSTNAIVESKTEDVGV
LVSSGPGIDPENFRQGGFFFPLSGSIDHRGKVIAAMEQDELAAAVRRCCDSGIRVYAAVGKFSTRNPDHEETMAHEAMQC
GDFVSMGHRLSGQLSFPRRVATAYYNSAVWRLYNSFADAVESSARAKGVTAPVHILKADGGTMPLAVSRRMPVESILSGP
AASVMGIVALYDIREDAVILDIGGTTTDIALFASGSPVIENDGISVGSYPTLVRALRTLSIGVGGDSRLRIAAGAVRVGP
DRSGPCVANGGTHVALMDAMNYLEVAAVGDVEASREAVRQLASLWDMYPEKLAREALDTAVNTICAAVDRLLDEVNAQPV
YTIIELLDGVKLNPGRVFVMGGPAAAFAPLLRNVMNRRIDVPRDHAVANAVGAALTRTTAELELFADTEKGLVFVPTLGL
RREAPLGYNLDDAVADAGRYLTESLAGMGIHIRPEDVDVLEAGSFNMVDMYGGKGRNIRVKCQVRPGISL
>Mature_550_residues
MYLGIDVGGTHTDAVVLDAQKRIQAWAKVPTLHHDLLSSVTQALDSVLQSVAAQDIVRLNLSTTLSTNAIVESKTEDVGV
LVSSGPGIDPENFRQGGFFFPLSGSIDHRGKVIAAMEQDELAAAVRRCCDSGIRVYAAVGKFSTRNPDHEETMAHEAMQC
GDFVSMGHRLSGQLSFPRRVATAYYNSAVWRLYNSFADAVESSARAKGVTAPVHILKADGGTMPLAVSRRMPVESILSGP
AASVMGIVALYDIREDAVILDIGGTTTDIALFASGSPVIENDGISVGSYPTLVRALRTLSIGVGGDSRLRIAAGAVRVGP
DRSGPCVANGGTHVALMDAMNYLEVAAVGDVEASREAVRQLASLWDMYPEKLAREALDTAVNTICAAVDRLLDEVNAQPV
YTIIELLDGVKLNPGRVFVMGGPAAAFAPLLRNVMNRRIDVPRDHAVANAVGAALTRTTAELELFADTEKGLVFVPTLGL
RREAPLGYNLDDAVADAGRYLTESLAGMGIHIRPEDVDVLEAGSFNMVDMYGGKGRNIRVKCQVRPGISL

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 58495; Mature: 58495

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLGIDVGGTHTDAVVLDAQKRIQAWAKVPTLHHDLLSSVTQALDSVLQSVAAQDIVRLN
CEEEEECCCCCCCEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
LSTTLSTNAIVESKTEDVGVLVSSGPGIDPENFRQGGFFFPLSGSIDHRGKVIAAMEQDE
EHHEECCCCEEECCCCCEEEEEECCCCCCHHHHCCCCEEEEECCCCCCCCCEEEEECHHH
LAAAVRRCCDSGIRVYAAVGKFSTRNPDHEETMAHEAMQCGDFVSMGHRLSGQLSFPRRV
HHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
ATAYYNSAVWRLYNSFADAVESSARAKGVTAPVHILKADGGTMPLAVSRRMPVESILSGP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEECCCCCHHHHHCCC
AASVMGIVALYDIREDAVILDIGGTTTDIALFASGSPVIENDGISVGSYPTLVRALRTLS
HHHHHHHHHHEECCCCEEEEECCCCCEEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHE
IGVGGDSRLRIAAGAVRVGPDRSGPCVANGGTHVALMDAMNYLEVAAVGDVEASREAVRQ
EECCCCCEEEEEECEEEECCCCCCCEEECCCCEEEHHHHHHHHHEEEECCCHHHHHHHHH
LASLWDMYPEKLAREALDTAVNTICAAVDRLLDEVNAQPVYTIIELLDGVKLNPGRVFVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCEEEEE
GGPAAAFAPLLRNVMNRRIDVPRDHAVANAVGAALTRTTAELELFADTEKGLVFVPTLGL
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCEEEEECCCC
RREAPLGYNLDDAVADAGRYLTESLAGMGIHIRPEDVDVLEAGSFNMVDMYGGKGRNIRV
CCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEECCCCCEEEECCCCCCCEEE
KCQVRPGISL
EEEECCCCCC
>Mature Secondary Structure
MYLGIDVGGTHTDAVVLDAQKRIQAWAKVPTLHHDLLSSVTQALDSVLQSVAAQDIVRLN
CEEEEECCCCCCCEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
LSTTLSTNAIVESKTEDVGVLVSSGPGIDPENFRQGGFFFPLSGSIDHRGKVIAAMEQDE
EHHEECCCCEEECCCCCEEEEEECCCCCCHHHHCCCCEEEEECCCCCCCCCEEEEECHHH
LAAAVRRCCDSGIRVYAAVGKFSTRNPDHEETMAHEAMQCGDFVSMGHRLSGQLSFPRRV
HHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
ATAYYNSAVWRLYNSFADAVESSARAKGVTAPVHILKADGGTMPLAVSRRMPVESILSGP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEECCCCCHHHHHCCC
AASVMGIVALYDIREDAVILDIGGTTTDIALFASGSPVIENDGISVGSYPTLVRALRTLS
HHHHHHHHHHEECCCCEEEEECCCCCEEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHE
IGVGGDSRLRIAAGAVRVGPDRSGPCVANGGTHVALMDAMNYLEVAAVGDVEASREAVRQ
EECCCCCEEEEEECEEEECCCCCCCEEECCCCEEEHHHHHHHHHEEEECCCHHHHHHHHH
LASLWDMYPEKLAREALDTAVNTICAAVDRLLDEVNAQPVYTIIELLDGVKLNPGRVFVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCEEEEE
GGPAAAFAPLLRNVMNRRIDVPRDHAVANAVGAALTRTTAELELFADTEKGLVFVPTLGL
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCEEEEECCCC
RREAPLGYNLDDAVADAGRYLTESLAGMGIHIRPEDVDVLEAGSFNMVDMYGGKGRNIRV
CCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEECCCCCEEEECCCCCCCEEE
KCQVRPGISL
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]