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The map label for this gene is secY

Identifier: 78357280

GI number: 78357280

Start: 2272738

End: 2274051

Strand: Reverse

Name: secY

Synonym: Dde_2237

Alternate gene names: 78357280

Gene position: 2274051-2272738 (Counterclockwise)

Preceding gene: 78357281

Following gene: 78357279

Centisome position: 60.96

GC content: 54.19

Gene sequence:

>1314_bases
GTGGCTTTGAGTGGTGTAGAAAATCTGGCGCGTCTGCCTGAGCTTAAGAAAAAGCTTTTGTGGACCTTCTTGTTGCTGGC
CGCATACCGCATCGGAATTCACGTTCCTGTGCCCGGGGTGGACTCTGCAGCTTTGGCAGACTTCTTTGCCAGTGTTCAGA
ACACCCTTTTCGGCCTCTTTGACATGTTCTCCGGGGGCGGACTTCGCAATCTGTCGATTTTCGCCCTCGGCATCATGCCC
TACATCTCCGCCTCCATCATCATCCAGCTTCTGCAGGTCGTAAGCCCTGAGCTGAAGCGGATGGCCAAGGAGGAGGGCGC
TGCGGGACGCAAGAAAATCACGCAGTACACCCGTTACGGTACCGTACTGATCGCCGTGATTCAGGGCTTCGGCATTGCCA
TGAGCCTTGAGAGCATGCAGAGCCCGACAGGGGCGTCTCTGGTACTGGCGCCCGGCTGGGGTTTCCGACTCACCACCATT
CTAACTCTCACCACAGGCACTGTGCTTATCATGTGGCTGGGTGAGCAAATAACCGAAAAGGGACTTGGCAACGGTATATC
GCTGGTCATCTTTTCGGGCATCGTCGCCGGACTGCCCGGCGGCCTGATGAAGACCATCCGCCTGATCGGCACGGGTGATC
TGAGCATTTTCATGGTGCTCATACTGCTTGTGTTCATGGCGGCTGTTCTTGCTTTCATCGTGTTTATGGAGCGTGGCCAG
CGCAGGATTCCCATCCATTACGCCAAGCGCCAGATGGGCCGTAAGATGTATGGCGGCCAGACTTCGCATCTTCCTTTGCG
GGTCAATACCGCCGGTGTCATTCCGCCCATTTTCGCATCCAGCCTTCTGCTTTTTCCCGCCACCGTGGCCAGTTTTTCCT
CGGTTGAGTGGCTGCAGACGGCTGCTGCGTATTTTGCTCCTCACACGTTGCTGTACAATGTAGTCTTTGTGGCTCTGATT
ATTTTCTTTGCGTTTTTCTATACTGCGATCATTTTTGATCCCAAAGATATCGCGGAAAACCTGAAAAATCAGGGCGGCTT
TGTTCCCGGGATACGTCCCGGCGTAAAGACCAGAGAATACATTGACAAAGTGCTTACCCGCATCACGGTGTGGGGTGCAC
TGTATATTGCCGCAATATGTGTTCTGCCCATGGTTCTTATCGCCAATATGAACGTTCCGTTCTATTTTGGCGGAACCGGG
CTGCTGATTGTCGTCGGGGTTGCCATGGACTTCATGTCCCAGGTGGAATCCCATCTGATCTCCCGACAGTACGAAGGCCT
CATGAACAAGGCCCGTATCAAGGGAAGGCGCTGA

Upstream 100 bases:

>100_bases
GCAATGTCGCCGTAAAAGTGGAAGCGCACAAGTTCAGTGCTTCTGCTGTTGAAAAGATCCAAAAAGCCGGTGGCGAAGCC
AAGGCACTGGAAGGTTAGCC

Downstream 100 bases:

>100_bases
CGGTGAAAAAGTATCGCGGTATCTTTCTCAAAAACGAGAAAGAGATAGGCTTCATGCGTGAAGCCAACCGGATTGTGGCT
ACAATTCTTGATGTCCTGGG

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MALSGVENLARLPELKKKLLWTFLLLAAYRIGIHVPVPGVDSAALADFFASVQNTLFGLFDMFSGGGLRNLSIFALGIMP
YISASIIIQLLQVVSPELKRMAKEEGAAGRKKITQYTRYGTVLIAVIQGFGIAMSLESMQSPTGASLVLAPGWGFRLTTI
LTLTTGTVLIMWLGEQITEKGLGNGISLVIFSGIVAGLPGGLMKTIRLIGTGDLSIFMVLILLVFMAAVLAFIVFMERGQ
RRIPIHYAKRQMGRKMYGGQTSHLPLRVNTAGVIPPIFASSLLLFPATVASFSSVEWLQTAAAYFAPHTLLYNVVFVALI
IFFAFFYTAIIFDPKDIAENLKNQGGFVPGIRPGVKTREYIDKVLTRITVWGALYIAAICVLPMVLIANMNVPFYFGGTG
LLIVVGVAMDFMSQVESHLISRQYEGLMNKARIKGRR

Sequences:

>Translated_437_residues
MALSGVENLARLPELKKKLLWTFLLLAAYRIGIHVPVPGVDSAALADFFASVQNTLFGLFDMFSGGGLRNLSIFALGIMP
YISASIIIQLLQVVSPELKRMAKEEGAAGRKKITQYTRYGTVLIAVIQGFGIAMSLESMQSPTGASLVLAPGWGFRLTTI
LTLTTGTVLIMWLGEQITEKGLGNGISLVIFSGIVAGLPGGLMKTIRLIGTGDLSIFMVLILLVFMAAVLAFIVFMERGQ
RRIPIHYAKRQMGRKMYGGQTSHLPLRVNTAGVIPPIFASSLLLFPATVASFSSVEWLQTAAAYFAPHTLLYNVVFVALI
IFFAFFYTAIIFDPKDIAENLKNQGGFVPGIRPGVKTREYIDKVLTRITVWGALYIAAICVLPMVLIANMNVPFYFGGTG
LLIVVGVAMDFMSQVESHLISRQYEGLMNKARIKGRR
>Mature_436_residues
ALSGVENLARLPELKKKLLWTFLLLAAYRIGIHVPVPGVDSAALADFFASVQNTLFGLFDMFSGGGLRNLSIFALGIMPY
ISASIIIQLLQVVSPELKRMAKEEGAAGRKKITQYTRYGTVLIAVIQGFGIAMSLESMQSPTGASLVLAPGWGFRLTTIL
TLTTGTVLIMWLGEQITEKGLGNGISLVIFSGIVAGLPGGLMKTIRLIGTGDLSIFMVLILLVFMAAVLAFIVFMERGQR
RIPIHYAKRQMGRKMYGGQTSHLPLRVNTAGVIPPIFASSLLLFPATVASFSSVEWLQTAAAYFAPHTLLYNVVFVALII
FFAFFYTAIIFDPKDIAENLKNQGGFVPGIRPGVKTREYIDKVLTRITVWGALYIAAICVLPMVLIANMNVPFYFGGTGL
LIVVGVAMDFMSQVESHLISRQYEGLMNKARIKGRR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=428, Percent_Identity=54.4392523364486, Blast_Score=426, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 47671; Mature: 47540

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSGVENLARLPELKKKLLWTFLLLAAYRIGIHVPVPGVDSAALADFFASVQNTLFGLF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DMFSGGGLRNLSIFALGIMPYISASIIIQLLQVVSPELKRMAKEEGAAGRKKITQYTRYG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHH
TVLIAVIQGFGIAMSLESMQSPTGASLVLAPGWGFRLTTILTLTTGTVLIMWLGEQITEK
HHHHHHHHHCCHHEEHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGNGISLVIFSGIVAGLPGGLMKTIRLIGTGDLSIFMVLILLVFMAAVLAFIVFMERGQ
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
RRIPIHYAKRQMGRKMYGGQTSHLPLRVNTAGVIPPIFASSLLLFPATVASFSSVEWLQT
CCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAAYFAPHTLLYNVVFVALIIFFAFFYTAIIFDPKDIAENLKNQGGFVPGIRPGVKTREY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHH
IDKVLTRITVWGALYIAAICVLPMVLIANMNVPFYFGGTGLLIVVGVAMDFMSQVESHLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
SRQYEGLMNKARIKGRR
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ALSGVENLARLPELKKKLLWTFLLLAAYRIGIHVPVPGVDSAALADFFASVQNTLFGLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DMFSGGGLRNLSIFALGIMPYISASIIIQLLQVVSPELKRMAKEEGAAGRKKITQYTRYG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHH
TVLIAVIQGFGIAMSLESMQSPTGASLVLAPGWGFRLTTILTLTTGTVLIMWLGEQITEK
HHHHHHHHHCCHHEEHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGNGISLVIFSGIVAGLPGGLMKTIRLIGTGDLSIFMVLILLVFMAAVLAFIVFMERGQ
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
RRIPIHYAKRQMGRKMYGGQTSHLPLRVNTAGVIPPIFASSLLLFPATVASFSSVEWLQT
CCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAAYFAPHTLLYNVVFVALIIFFAFFYTAIIFDPKDIAENLKNQGGFVPGIRPGVKTREY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHH
IDKVLTRITVWGALYIAAICVLPMVLIANMNVPFYFGGTGLLIVVGVAMDFMSQVESHLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
SRQYEGLMNKARIKGRR
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]