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The map label for this gene is resA [H]

Identifier: 78357157

GI number: 78357157

Start: 2162411

End: 2162890

Strand: Reverse

Name: resA [H]

Synonym: Dde_2114

Alternate gene names: 78357157

Gene position: 2162890-2162411 (Counterclockwise)

Preceding gene: 78357158

Following gene: 78357156

Centisome position: 57.98

GC content: 56.25

Gene sequence:

>480_bases
ATGAGACGTTCTTTTTTGATCATGCGGACGATGCTGACGGTGTGCTGCCTTGTTGTCCTGTGGGCCGGAGCTGTCCGCGC
CGCGGATGTGCAGGAAGGCGGGTCGGCGCTGTTGCTTGACTCCATTGCCGCGCAGAGCGGAAAACCCGTACTGGTGAATT
TTTTTGCCAGCTGGTGCCCCCCCTGCAAAGAGGAAATTCCGGGCCTTGTCTCACTGCGTTCGCAGTATGCGGCGGATGAC
GTGGCCATTATCGGGGTGTCGCTGGATGAAAGCCGCTCGGCGCTGGACCGCATGATTCAGGATTTTGGAATCAATTATCC
TGTTATCCGGGGCAACCGTGAACTGGCGGGCACTTTCGGCGTTACCGGCATTCCCCGTCTTCTTGTCTATTCCGCTGAGG
GCAAGCTGGTCTCCGACCACCTGGGCTACATGACGGAAGAAGAACTCAGACAGCTTATTGACGCGAACATTGTAAAATAA

Upstream 100 bases:

>100_bases
CATCGGCGCAGCGGGATACTCCCGCGATGCCGTGGAAGCGGTGAGAATTGCGCGGGGGCTTGTGGAAGCTCCAGCCAGAG
TGCAGTGAGGAGTTACAGAT

Downstream 100 bases:

>100_bases
AGGCTGCGCAATGACGTATTTACGTAAAGCCCGTATTCAGGATGTGAAGGCCATCCACGCACTTCTCATGCACCATGCCG
CAGGCGGGTTGCTGTTGCCG

Product: thioredoxin family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MRRSFLIMRTMLTVCCLVVLWAGAVRAADVQEGGSALLLDSIAAQSGKPVLVNFFASWCPPCKEEIPGLVSLRSQYAADD
VAIIGVSLDESRSALDRMIQDFGINYPVIRGNRELAGTFGVTGIPRLLVYSAEGKLVSDHLGYMTEEELRQLIDANIVK

Sequences:

>Translated_159_residues
MRRSFLIMRTMLTVCCLVVLWAGAVRAADVQEGGSALLLDSIAAQSGKPVLVNFFASWCPPCKEEIPGLVSLRSQYAADD
VAIIGVSLDESRSALDRMIQDFGINYPVIRGNRELAGTFGVTGIPRLLVYSAEGKLVSDHLGYMTEEELRQLIDANIVK
>Mature_159_residues
MRRSFLIMRTMLTVCCLVVLWAGAVRAADVQEGGSALLLDSIAAQSGKPVLVNFFASWCPPCKEEIPGLVSLRSQYAADD
VAIIGVSLDESRSALDRMIQDFGINYPVIRGNRELAGTFGVTGIPRLLVYSAEGKLVSDHLGYMTEEELRQLIDANIVK

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 17333; Mature: 17333

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSFLIMRTMLTVCCLVVLWAGAVRAADVQEGGSALLLDSIAAQSGKPVLVNFFASWCP
CCCHHHHHHHHHHHHHHHHHHHCCHHHCHHHCCCCEEEHHHHHHCCCCCHHHHHHHHHCC
PCKEEIPGLVSLRSQYAADDVAIIGVSLDESRSALDRMIQDFGINYPVIRGNRELAGTFG
CHHHHCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCC
VTGIPRLLVYSAEGKLVSDHLGYMTEEELRQLIDANIVK
CCCCCHHEEECCCCCCHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MRRSFLIMRTMLTVCCLVVLWAGAVRAADVQEGGSALLLDSIAAQSGKPVLVNFFASWCP
CCCHHHHHHHHHHHHHHHHHHHCCHHHCHHHCCCCEEEHHHHHHCCCCCHHHHHHHHHCC
PCKEEIPGLVSLRSQYAADDVAIIGVSLDESRSALDRMIQDFGINYPVIRGNRELAGTFG
CHHHHCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCC
VTGIPRLLVYSAEGKLVSDHLGYMTEEELRQLIDANIVK
CCCCCHHEEECCCCCCHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 12637552 [H]