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The map label for this gene is paaK [H]

Identifier: 78357127

GI number: 78357127

Start: 2131405

End: 2132706

Strand: Direct

Name: paaK [H]

Synonym: Dde_2084

Alternate gene names: 78357127

Gene position: 2131405-2132706 (Clockwise)

Preceding gene: 78357126

Following gene: 78357131

Centisome position: 57.14

GC content: 56.14

Gene sequence:

>1302_bases
ATGATTTATGATGTGGACCGCGAAACACTGCCGCGGGAAGAGCTTGAAGCTCTTCAGGTGAGGCGTCTGAAAAACCTTTG
TGAACGGGTTTATGCGAATGTGCCCCATTACAGACGCAAGTTTGACGAAGCGGGAATAACCCCTGCGGACATCAAAAGCC
TTTCCGACCTCAAGTATCTGCCGTTTACCGAGAAGCAGGACCTACGCAACAACTATCCTTACGGCCTGTTTGCCGTGCCA
AAGGAGCACATCGTGCGCCTGCACGCCTCCAGCGGCACCACAGGCAAAGCCACAGTGGTGGGCTATACCGCGCGCGATCT
CAACAACTGGGCTGAAATGATGGCACGCAGCTTCACCGCGGGCGGGCTTTCCAGCCGCGACCTGATCCATAACGCATACG
GTTACGGCCTGTTCACGGGCGGGCTGGGAGCGCATTACGGTGCCGAAAAGCTCGGCGCAACGGTCATTCCGGTATCCGGC
GGCAACACCAAAAGGCAGGTGGTTCTGCTGCGCGATTTCGGCGCCACAGCCATCTGCTGTACCCCTTCGTACAGCCTGTA
TCTGTACGAAGCCGCGCTGGAAGCCGGTATCGACATGCGCGAACTGCCGCTGCGCATCGGTATTTTCGGCGCAGAGCCGT
GGACCGATGAAATGCGCCACGACATCGAACAGAAAATGGGCATCTCGGCCGTCAACATATACGGCCTGTCAGAAATCATG
GGGCCGGGAGTCTCCATGGAATGTGAAGACGCCAAAGACGGCATGCACATATGGGAAGACCACTTCCTGCCTGAGATAAT
AGACCCCGTCACGGGCGAACAGCTGCCCGCGGGACAGCAGGGCGAACTGGTCATCACCACGCTGACCAAAGAAGGCATTC
CGCTTATCCGTTACCGCACGCGTGACATCAGCATGCTGAATTACACCCCGTGCTGCTGCGGCAGAACCCATGTACGTATG
AAGCGTGTCATGGGCCGCAGCGACGACATGCTGATTATCCGCGGGGTCAATGTATTCCCCTCGCAGATCGAGTCCATTCT
GCTGGAAACTGAAGGAGCCTCTCCGCACTATCAGATAGTTGTCAAACGGGATGGCAATCTGGATATCATGGAAGTGCATG
TTGAAGTTTCGGAAAATCTGTTTTCGGACGAAATCAAAAACCTCCAGCGGCTTGAAAGCCGCATTCAGAAAACCATCAAG
GAATTCCTCGGCGTCACAGCCAGGGTACGCCTTGTGGACCCCCGCTCGATCCAGCGTTCGGAAGGCAAAGCCAAACGGGT
TCTCGACCTGCGCAACGAATAA

Upstream 100 bases:

>100_bases
TGGTGCAGACAAACAGTTTACGTCCGTTTCAGTACGGGCATCCTGCTATATCTCGGTAGACATATTAATTTTCTGGAAAG
CGCCAGAGGGAGACAACGGC

Downstream 100 bases:

>100_bases
CATTCCGGCAGCTCGGCCATAAAAAAGGGAAGCAGATGCTTCCCTTTTTTATGGCCGCATGACAGCAGCCGGTAAACGGA
CAACACGGTCATTTTTTTCT

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MIYDVDRETLPREELEALQVRRLKNLCERVYANVPHYRRKFDEAGITPADIKSLSDLKYLPFTEKQDLRNNYPYGLFAVP
KEHIVRLHASSGTTGKATVVGYTARDLNNWAEMMARSFTAGGLSSRDLIHNAYGYGLFTGGLGAHYGAEKLGATVIPVSG
GNTKRQVVLLRDFGATAICCTPSYSLYLYEAALEAGIDMRELPLRIGIFGAEPWTDEMRHDIEQKMGISAVNIYGLSEIM
GPGVSMECEDAKDGMHIWEDHFLPEIIDPVTGEQLPAGQQGELVITTLTKEGIPLIRYRTRDISMLNYTPCCCGRTHVRM
KRVMGRSDDMLIIRGVNVFPSQIESILLETEGASPHYQIVVKRDGNLDIMEVHVEVSENLFSDEIKNLQRLESRIQKTIK
EFLGVTARVRLVDPRSIQRSEGKAKRVLDLRNE

Sequences:

>Translated_433_residues
MIYDVDRETLPREELEALQVRRLKNLCERVYANVPHYRRKFDEAGITPADIKSLSDLKYLPFTEKQDLRNNYPYGLFAVP
KEHIVRLHASSGTTGKATVVGYTARDLNNWAEMMARSFTAGGLSSRDLIHNAYGYGLFTGGLGAHYGAEKLGATVIPVSG
GNTKRQVVLLRDFGATAICCTPSYSLYLYEAALEAGIDMRELPLRIGIFGAEPWTDEMRHDIEQKMGISAVNIYGLSEIM
GPGVSMECEDAKDGMHIWEDHFLPEIIDPVTGEQLPAGQQGELVITTLTKEGIPLIRYRTRDISMLNYTPCCCGRTHVRM
KRVMGRSDDMLIIRGVNVFPSQIESILLETEGASPHYQIVVKRDGNLDIMEVHVEVSENLFSDEIKNLQRLESRIQKTIK
EFLGVTARVRLVDPRSIQRSEGKAKRVLDLRNE
>Mature_433_residues
MIYDVDRETLPREELEALQVRRLKNLCERVYANVPHYRRKFDEAGITPADIKSLSDLKYLPFTEKQDLRNNYPYGLFAVP
KEHIVRLHASSGTTGKATVVGYTARDLNNWAEMMARSFTAGGLSSRDLIHNAYGYGLFTGGLGAHYGAEKLGATVIPVSG
GNTKRQVVLLRDFGATAICCTPSYSLYLYEAALEAGIDMRELPLRIGIFGAEPWTDEMRHDIEQKMGISAVNIYGLSEIM
GPGVSMECEDAKDGMHIWEDHFLPEIIDPVTGEQLPAGQQGELVITTLTKEGIPLIRYRTRDISMLNYTPCCCGRTHVRM
KRVMGRSDDMLIIRGVNVFPSQIESILLETEGASPHYQIVVKRDGNLDIMEVHVEVSENLFSDEIKNLQRLESRIQKTIK
EFLGVTARVRLVDPRSIQRSEGKAKRVLDLRNE

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=426, Percent_Identity=56.3380281690141, Blast_Score=474, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48697; Mature: 48697

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYDVDRETLPREELEALQVRRLKNLCERVYANVPHYRRKFDEAGITPADIKSLSDLKYL
CEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCCCC
PFTEKQDLRNNYPYGLFAVPKEHIVRLHASSGTTGKATVVGYTARDLNNWAEMMARSFTA
CCCCHHHHHCCCCEEEEECCHHHEEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCC
GGLSSRDLIHNAYGYGLFTGGLGAHYGAEKLGATVIPVSGGNTKRQVVLLRDFGATAICC
CCCCCHHHHHHHCCCEEEECCCCCCCCHHHHCCEEEEECCCCCCEEEEEEEECCCEEEEE
TPSYSLYLYEAALEAGIDMRELPLRIGIFGAEPWTDEMRHDIEQKMGISAVNIYGLSEIM
CCCCEEEEEEEHHHHCCCHHHCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEHHHHH
GPGVSMECEDAKDGMHIWEDHFLPEIIDPVTGEQLPAGQQGELVITTLTKEGIPLIRYRT
CCCCCEECCCCCCCCHHHHHCCCHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEC
RDISMLNYTPCCCGRTHVRMKRVMGRSDDMLIIRGVNVFPSQIESILLETEGASPHYQIV
CCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHEEECCCCCCCEEEE
VKRDGNLDIMEVHVEVSENLFSDEIKNLQRLESRIQKTIKEFLGVTARVRLVDPRSIQRS
EEECCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHC
EGKAKRVLDLRNE
CCCHHHHHCCCCC
>Mature Secondary Structure
MIYDVDRETLPREELEALQVRRLKNLCERVYANVPHYRRKFDEAGITPADIKSLSDLKYL
CEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCCCC
PFTEKQDLRNNYPYGLFAVPKEHIVRLHASSGTTGKATVVGYTARDLNNWAEMMARSFTA
CCCCHHHHHCCCCEEEEECCHHHEEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCC
GGLSSRDLIHNAYGYGLFTGGLGAHYGAEKLGATVIPVSGGNTKRQVVLLRDFGATAICC
CCCCCHHHHHHHCCCEEEECCCCCCCCHHHHCCEEEEECCCCCCEEEEEEEECCCEEEEE
TPSYSLYLYEAALEAGIDMRELPLRIGIFGAEPWTDEMRHDIEQKMGISAVNIYGLSEIM
CCCCEEEEEEEHHHHCCCHHHCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEHHHHH
GPGVSMECEDAKDGMHIWEDHFLPEIIDPVTGEQLPAGQQGELVITTLTKEGIPLIRYRT
CCCCCEECCCCCCCCHHHHHCCCHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEC
RDISMLNYTPCCCGRTHVRMKRVMGRSDDMLIIRGVNVFPSQIESILLETEGASPHYQIV
CCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHEEECCCCCCCEEEE
VKRDGNLDIMEVHVEVSENLFSDEIKNLQRLESRIQKTIKEFLGVTARVRLVDPRSIQRS
EEECCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHC
EGKAKRVLDLRNE
CCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]