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The map label for this gene is trkA

Identifier: 78357073

GI number: 78357073

Start: 2069695

End: 2071092

Strand: Reverse

Name: trkA

Synonym: Dde_2030

Alternate gene names: 78357073

Gene position: 2071092-2069695 (Counterclockwise)

Preceding gene: 78357074

Following gene: 78357072

Centisome position: 55.52

GC content: 54.29

Gene sequence:

>1398_bases
ATGCGTTTGTTTCGTAAAGAACCGAAAGCTGAACAGCTCAAGGTTATTATTATCGGCGCGGGTGAGGTGGGCTACCACAT
AGCCCACAGGCTGACCCGTGAGAATAAACAGGTTGTGGTGGTGGACCAGCAGCCCGAAGCCCTGCGCAGGGTGGCCGAGG
CTCTTGATGTACAGACCATCAGGGGGTCGGGATCCAGCCCCGTGGTGCTGCACGACGCCGGTGCAGAAGATGCCGATATT
ATTCTGGCGGTGACAGACAGTGACGAGATCAATATCATAGCATGTCTGTTCGCCAATATTATTTCGCCTGCTTCTACCAA
GCTGGCCCGCATACGCAATGAAGAATATACGCTGTACCGCGATGCTCTGGCTCAGGATATTCTTAATATAAGCATGATCA
TCAATCCTGAAGTGGAAGTGGTAAAAAACATCGACCGGCTGCTTTCGTTGCCGGGAGCCGTTGATTACAGCGAGTTTGCC
GACGGACGCATCCGCATGGTGGGCATGCGTATATGTTCCGGACCTCTTGTCGGTGTGCGGCTGATGAATTTCCGGACGGT
GATTTCCGACGGCGATGTGATCATTGCGGCCATAGTGCGCAATGATGAGCTGATAATTCCTACCGGTATGGATGAAATCA
GAGCAGACGACGTGGTCTACTTTGTCTGCACCGAATCCAGCCTGGAATCGGTCCGCAATGTGGTTGCCGCTCTGGAAGAC
CCTATCCGGAGTGCTCTTATTGTGGGTGGTGGAAACATAGGTATGCGTCTTGCCACGCTTTTCGAGCGTAAAGGTTATCA
TACCAAACTTGTCGACCGCGATGAGGAACGCTGTGCTGTGCTGGCAGAAAAGCTGAACTCGACCATTGTTCTGCACGGTG
ACGGCACCGATCAGGATCTGCTGCGTGAAGAAAACGCCGGAACCATGGATGCCGTTGTGTGTCTGACTTCTGATGAAGAG
ACCAATATTCTCTGCTCACTGCTGGCAAAGAATATGGGCGTGCGCAAAACCGTTGCGCGCATCAACAAGGTGGCTTACCA
GCCGCTTGTCCGCGCCATCGGCATCGAGCATTCGGTCAGCCCGCGTCTGTCAGCCGTGAACAGCATTCTGCATTATATCC
GCAAAGGAAAGGTGCTTTCTTCAGTAGCCATCCGCGGGGAAGAGGCTGAAGTGATGGAGGCGCTGGCGGAAGCGCAGTCA
GATATTGTGGGCAGACCCATCCATAAGCTGAGCTTTCCCAAGGGAGCGCTGGTGCTGGCTCTGGTGCGCGGCACCGAGGT
CGTCATCCCCAGCGGCGACACTGTTATCGAGCCGCAGGACCGCATCCTGATTCTTTCCACACGTCAGGCGGTTTCCGATG
TTGAGCAGGCTCTTATGGTCAAGCTCAAGGCGTACTAG

Upstream 100 bases:

>100_bases
CATGTTATAGCGGTTGAACAGGCCCCGTCCTTTTGCTAGTGACCATGGTTGACCGGCAGATGCGTCCCTCTGGTTTCATC
TTTTGAGAACGGATTGCACA

Downstream 100 bases:

>100_bases
GCGGCTTGTAATGCGTATCGGCTATACATTGTATGTCATCGGGGCGTTGCTTTGCTCCGTTGGACTTACCATGATTTTTC
CGCTGATGTTCGGCGTATAC

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MRLFRKEPKAEQLKVIIIGAGEVGYHIAHRLTRENKQVVVVDQQPEALRRVAEALDVQTIRGSGSSPVVLHDAGAEDADI
ILAVTDSDEINIIACLFANIISPASTKLARIRNEEYTLYRDALAQDILNISMIINPEVEVVKNIDRLLSLPGAVDYSEFA
DGRIRMVGMRICSGPLVGVRLMNFRTVISDGDVIIAAIVRNDELIIPTGMDEIRADDVVYFVCTESSLESVRNVVAALED
PIRSALIVGGGNIGMRLATLFERKGYHTKLVDRDEERCAVLAEKLNSTIVLHGDGTDQDLLREENAGTMDAVVCLTSDEE
TNILCSLLAKNMGVRKTVARINKVAYQPLVRAIGIEHSVSPRLSAVNSILHYIRKGKVLSSVAIRGEEAEVMEALAEAQS
DIVGRPIHKLSFPKGALVLALVRGTEVVIPSGDTVIEPQDRILILSTRQAVSDVEQALMVKLKAY

Sequences:

>Translated_465_residues
MRLFRKEPKAEQLKVIIIGAGEVGYHIAHRLTRENKQVVVVDQQPEALRRVAEALDVQTIRGSGSSPVVLHDAGAEDADI
ILAVTDSDEINIIACLFANIISPASTKLARIRNEEYTLYRDALAQDILNISMIINPEVEVVKNIDRLLSLPGAVDYSEFA
DGRIRMVGMRICSGPLVGVRLMNFRTVISDGDVIIAAIVRNDELIIPTGMDEIRADDVVYFVCTESSLESVRNVVAALED
PIRSALIVGGGNIGMRLATLFERKGYHTKLVDRDEERCAVLAEKLNSTIVLHGDGTDQDLLREENAGTMDAVVCLTSDEE
TNILCSLLAKNMGVRKTVARINKVAYQPLVRAIGIEHSVSPRLSAVNSILHYIRKGKVLSSVAIRGEEAEVMEALAEAQS
DIVGRPIHKLSFPKGALVLALVRGTEVVIPSGDTVIEPQDRILILSTRQAVSDVEQALMVKLKAY
>Mature_465_residues
MRLFRKEPKAEQLKVIIIGAGEVGYHIAHRLTRENKQVVVVDQQPEALRRVAEALDVQTIRGSGSSPVVLHDAGAEDADI
ILAVTDSDEINIIACLFANIISPASTKLARIRNEEYTLYRDALAQDILNISMIINPEVEVVKNIDRLLSLPGAVDYSEFA
DGRIRMVGMRICSGPLVGVRLMNFRTVISDGDVIIAAIVRNDELIIPTGMDEIRADDVVYFVCTESSLESVRNVVAALED
PIRSALIVGGGNIGMRLATLFERKGYHTKLVDRDEERCAVLAEKLNSTIVLHGDGTDQDLLREENAGTMDAVVCLTSDEE
TNILCSLLAKNMGVRKTVARINKVAYQPLVRAIGIEHSVSPRLSAVNSILHYIRKGKVLSSVAIRGEEAEVMEALAEAQS
DIVGRPIHKLSFPKGALVLALVRGTEVVIPSGDTVIEPQDRILILSTRQAVSDVEQALMVKLKAY

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=450, Percent_Identity=38, Blast_Score=300, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 50825; Mature: 50825

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFRKEPKAEQLKVIIIGAGEVGYHIAHRLTRENKQVVVVDQQPEALRRVAEALDVQTI
CCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCEEE
RGSGSSPVVLHDAGAEDADIILAVTDSDEINIIACLFANIISPASTKLARIRNEEYTLYR
CCCCCCCEEEEECCCCCCEEEEEEECCCCCEEHHHHHHHHHCCCHHHHHHHCCCCHHHHH
DALAQDILNISMIINPEVEVVKNIDRLLSLPGAVDYSEFADGRIRMVGMRICSGPLVGVR
HHHHHHHHEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHCCCEEEEEEEEECCCCEEEEE
LMNFRTVISDGDVIIAAIVRNDELIIPTGMDEIRADDVVYFVCTESSLESVRNVVAALED
EEEEEEEECCCCEEEEEEECCCCEEEECCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHH
PIRSALIVGGGNIGMRLATLFERKGYHTKLVDRDEERCAVLAEKLNSTIVLHGDGTDQDL
HHHCEEEEECCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCEEEEECCCCCHHH
LREENAGTMDAVVCLTSDEETNILCSLLAKNMGVRKTVARINKVAYQPLVRAIGIEHSVS
HHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
PRLSAVNSILHYIRKGKVLSSVAIRGEEAEVMEALAEAQSDIVGRPIHKLSFPKGALVLA
HHHHHHHHHHHHHHCCCHHHHHEECCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEE
LVRGTEVVIPSGDTVIEPQDRILILSTRQAVSDVEQALMVKLKAY
EECCCEEEECCCCEEECCCCCEEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLFRKEPKAEQLKVIIIGAGEVGYHIAHRLTRENKQVVVVDQQPEALRRVAEALDVQTI
CCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCEEE
RGSGSSPVVLHDAGAEDADIILAVTDSDEINIIACLFANIISPASTKLARIRNEEYTLYR
CCCCCCCEEEEECCCCCCEEEEEEECCCCCEEHHHHHHHHHCCCHHHHHHHCCCCHHHHH
DALAQDILNISMIINPEVEVVKNIDRLLSLPGAVDYSEFADGRIRMVGMRICSGPLVGVR
HHHHHHHHEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHCCCEEEEEEEEECCCCEEEEE
LMNFRTVISDGDVIIAAIVRNDELIIPTGMDEIRADDVVYFVCTESSLESVRNVVAALED
EEEEEEEECCCCEEEEEEECCCCEEEECCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHH
PIRSALIVGGGNIGMRLATLFERKGYHTKLVDRDEERCAVLAEKLNSTIVLHGDGTDQDL
HHHCEEEEECCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCEEEEECCCCCHHH
LREENAGTMDAVVCLTSDEETNILCSLLAKNMGVRKTVARINKVAYQPLVRAIGIEHSVS
HHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
PRLSAVNSILHYIRKGKVLSSVAIRGEEAEVMEALAEAQSDIVGRPIHKLSFPKGALVLA
HHHHHHHHHHHHHHCCCHHHHHEECCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEE
LVRGTEVVIPSGDTVIEPQDRILILSTRQAVSDVEQALMVKLKAY
EECCCEEEECCCCEEECCCCCEEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7948029; 9720051 [H]