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The map label for this gene is trkH [H]

Identifier: 78357072

GI number: 78357072

Start: 2068239

End: 2069684

Strand: Reverse

Name: trkH [H]

Synonym: Dde_2029

Alternate gene names: 78357072

Gene position: 2069684-2068239 (Counterclockwise)

Preceding gene: 78357073

Following gene: 78357065

Centisome position: 55.48

GC content: 53.11

Gene sequence:

>1446_bases
ATGCGTATCGGCTATACATTGTATGTCATCGGGGCGTTGCTTTGCTCCGTTGGACTTACCATGATTTTTCCGCTGATGTT
CGGCGTATACTATCAGGATGAAAGTATATTGCCGCTTTTGTACTCCATGGGGATAACAGTGATTGCGGGCGGCTGCCTGA
TTGCCGTTTTCCGTGAGCGGACCAAAACCCTGCTGAACCACAGAGAAGGCATGGCTATTGTGGCTCTGGGGTGGATAGGG
GCGGGTATTGCCGGAGCGCTTCCTTTCTGGTTCGGCGGCATGTTGGGATTTACCGACGCGCTTTTCGAATCCGTTTCTGG
CTTTACCACCACCGGCTCCACGGTGCTGACTGATATCGAAATAGTCCCCCGCGGTCTGCTTATGTGGCGTAGCCTCACCC
ATTGGCTTGGGGGCATGGGGATTATTGTGCTTTCACTTGCCATTCTGCCTTTTCTCGGCGTGGGGGGCATGCAGCTGTAC
AAAGCCGAAGTGCCCGGCCCTGTGCCTGACAAGCTCAAGCCCCGCATCAAAGATACAGCCATGGCTCTATGGAAGGTCTA
TCTGCTTTTTTCCGTGCTGCAGGCTGTGTTGCTGTATTTCGGGGGAATGGATGTGTTCGACTCCATCTGCCATACATTCG
GCACCATGGCCACGGGCGGTTTTTCAACCAAGAATGCTTCTGTGGGGCACTACGACAGCGGATACCTGCAGACCGTCATC
ATTATATTCATGTTCATCGCGGGTGTTAATTTTTCTCTGCATTTCCGTCTGCTGCTGGGAGAGCCCGGGGCTTTTCTCAA
GGATGCGGAATTTCGTTTTTATACGGTCGTGGTGCTTGTCAGTACGGCTGTGGTTGCACTGGCCGTGTATGGCACAGAGT
ACGACAGTTTTCTTGAAGCATTGCGTCATGCGGCTTTTCAGGTTGTTTCCATCTGTACAACAACCGGGTTTGCCACGGCG
GATTATGAACAGTGGGCGCCCGTAACCATGGCAGTATTGTTGTTTCTGACGTTTCTTGGCGGGTGTGCAGGGTCCACCGG
CGGCGGCATTAAATGTATGAGAGTGCTGTTGCTGCTCAAGCAGGCATATCATGAAATTTTCAGACTGATCCATCCGCACT
CGGTATCTTATGTCAAGCTGGGCAACCGCATTGTGCGGGCAGAGGTACTTTCCGGTGTGCTGGGATTTTTTGTTCTGTAT
ATCGGGTTGTTTGTACTGTCATCCACGCTCATAGCAGCTATGGGGGTTGATGTGCTGACGGCCTTTTCCGCCACGGCGGC
CTGCATAGGCAATATCGGCCCGGGACTGGGGTCCGTAGGTCCCGCCGAGAATTTTGCCCACCTGCCTCAGGCTGCCAAGT
GGGTGCTGACACTGTGCATGCTGCTGGGCAGACTGGAAATCTATACTGTTTTCATCCTTTTTGTGCCTGAGTTCTGGCGC
AAGTAA

Upstream 100 bases:

>100_bases
GAGCCGCAGGACCGCATCCTGATTCTTTCCACACGTCAGGCGGTTTCCGATGTTGAGCAGGCTCTTATGGTCAAGCTCAA
GGCGTACTAGGCGGCTTGTA

Downstream 100 bases:

>100_bases
CCGGCCGTTGGCGCTGGCAGTGGTGCGGAAGGTACACGCGCGCAGAACATGTACCGCCTGCTTGCTGTCGGTGCGTTATG
CATAAGAAAAGGCCCCCGCT

Product: K+ transporter Trk

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MRIGYTLYVIGALLCSVGLTMIFPLMFGVYYQDESILPLLYSMGITVIAGGCLIAVFRERTKTLLNHREGMAIVALGWIG
AGIAGALPFWFGGMLGFTDALFESVSGFTTTGSTVLTDIEIVPRGLLMWRSLTHWLGGMGIIVLSLAILPFLGVGGMQLY
KAEVPGPVPDKLKPRIKDTAMALWKVYLLFSVLQAVLLYFGGMDVFDSICHTFGTMATGGFSTKNASVGHYDSGYLQTVI
IIFMFIAGVNFSLHFRLLLGEPGAFLKDAEFRFYTVVVLVSTAVVALAVYGTEYDSFLEALRHAAFQVVSICTTTGFATA
DYEQWAPVTMAVLLFLTFLGGCAGSTGGGIKCMRVLLLLKQAYHEIFRLIHPHSVSYVKLGNRIVRAEVLSGVLGFFVLY
IGLFVLSSTLIAAMGVDVLTAFSATAACIGNIGPGLGSVGPAENFAHLPQAAKWVLTLCMLLGRLEIYTVFILFVPEFWR
K

Sequences:

>Translated_481_residues
MRIGYTLYVIGALLCSVGLTMIFPLMFGVYYQDESILPLLYSMGITVIAGGCLIAVFRERTKTLLNHREGMAIVALGWIG
AGIAGALPFWFGGMLGFTDALFESVSGFTTTGSTVLTDIEIVPRGLLMWRSLTHWLGGMGIIVLSLAILPFLGVGGMQLY
KAEVPGPVPDKLKPRIKDTAMALWKVYLLFSVLQAVLLYFGGMDVFDSICHTFGTMATGGFSTKNASVGHYDSGYLQTVI
IIFMFIAGVNFSLHFRLLLGEPGAFLKDAEFRFYTVVVLVSTAVVALAVYGTEYDSFLEALRHAAFQVVSICTTTGFATA
DYEQWAPVTMAVLLFLTFLGGCAGSTGGGIKCMRVLLLLKQAYHEIFRLIHPHSVSYVKLGNRIVRAEVLSGVLGFFVLY
IGLFVLSSTLIAAMGVDVLTAFSATAACIGNIGPGLGSVGPAENFAHLPQAAKWVLTLCMLLGRLEIYTVFILFVPEFWR
K
>Mature_481_residues
MRIGYTLYVIGALLCSVGLTMIFPLMFGVYYQDESILPLLYSMGITVIAGGCLIAVFRERTKTLLNHREGMAIVALGWIG
AGIAGALPFWFGGMLGFTDALFESVSGFTTTGSTVLTDIEIVPRGLLMWRSLTHWLGGMGIIVLSLAILPFLGVGGMQLY
KAEVPGPVPDKLKPRIKDTAMALWKVYLLFSVLQAVLLYFGGMDVFDSICHTFGTMATGGFSTKNASVGHYDSGYLQTVI
IIFMFIAGVNFSLHFRLLLGEPGAFLKDAEFRFYTVVVLVSTAVVALAVYGTEYDSFLEALRHAAFQVVSICTTTGFATA
DYEQWAPVTMAVLLFLTFLGGCAGSTGGGIKCMRVLLLLKQAYHEIFRLIHPHSVSYVKLGNRIVRAEVLSGVLGFFVLY
IGLFVLSSTLIAAMGVDVLTAFSATAACIGNIGPGLGSVGPAENFAHLPQAAKWVLTLCMLLGRLEIYTVFILFVPEFWR
K

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=479, Percent_Identity=45.0939457202505, Blast_Score=348, Evalue=4e-97,
Organism=Escherichia coli, GI1787626, Length=478, Percent_Identity=37.4476987447699, Blast_Score=310, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52143; Mature: 52143

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGYTLYVIGALLCSVGLTMIFPLMFGVYYQDESILPLLYSMGITVIAGGCLIAVFRER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
TKTLLNHREGMAIVALGWIGAGIAGALPFWFGGMLGFTDALFESVSGFTTTGSTVLTDIE
HHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
IVPRGLLMWRSLTHWLGGMGIIVLSLAILPFLGVGGMQLYKAEVPGPVPDKLKPRIKDTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHH
MALWKVYLLFSVLQAVLLYFGGMDVFDSICHTFGTMATGGFSTKNASVGHYDSGYLQTVI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
IIFMFIAGVNFSLHFRLLLGEPGAFLKDAEFRFYTVVVLVSTAVVALAVYGTEYDSFLEA
HHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LRHAAFQVVSICTTTGFATADYEQWAPVTMAVLLFLTFLGGCAGSTGGGIKCMRVLLLLK
HHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
QAYHEIFRLIHPHSVSYVKLGNRIVRAEVLSGVLGFFVLYIGLFVLSSTLIAAMGVDVLT
HHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFSATAACIGNIGPGLGSVGPAENFAHLPQAAKWVLTLCMLLGRLEIYTVFILFVPEFWR
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
K
C
>Mature Secondary Structure
MRIGYTLYVIGALLCSVGLTMIFPLMFGVYYQDESILPLLYSMGITVIAGGCLIAVFRER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
TKTLLNHREGMAIVALGWIGAGIAGALPFWFGGMLGFTDALFESVSGFTTTGSTVLTDIE
HHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
IVPRGLLMWRSLTHWLGGMGIIVLSLAILPFLGVGGMQLYKAEVPGPVPDKLKPRIKDTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHH
MALWKVYLLFSVLQAVLLYFGGMDVFDSICHTFGTMATGGFSTKNASVGHYDSGYLQTVI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
IIFMFIAGVNFSLHFRLLLGEPGAFLKDAEFRFYTVVVLVSTAVVALAVYGTEYDSFLEA
HHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LRHAAFQVVSICTTTGFATADYEQWAPVTMAVLLFLTFLGGCAGSTGGGIKCMRVLLLLK
HHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
QAYHEIFRLIHPHSVSYVKLGNRIVRAEVLSGVLGFFVLYIGLFVLSSTLIAAMGVDVLT
HHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFSATAACIGNIGPGLGSVGPAENFAHLPQAAKWVLTLCMLLGRLEIYTVFILFVPEFWR
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]