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The map label for this gene is mreB [H]

Identifier: 78357036

GI number: 78357036

Start: 2035057

End: 2036079

Strand: Reverse

Name: mreB [H]

Synonym: Dde_1993

Alternate gene names: 78357036

Gene position: 2036079-2035057 (Counterclockwise)

Preceding gene: 78357037

Following gene: 78357035

Centisome position: 54.58

GC content: 55.13

Gene sequence:

>1023_bases
ATGTTTGGAAAACTTTTCGGGTTCCTGGGCAAGGACCTGGCCATGGATCTGGGCACGGCCAACACGCTGCTGTATACCAG
AACCGAGGGCATAGTTCTTAACGAGCCTTCTGTGGTTGCCATAGACCAGCAGCGCAACACCGTGCTGGCTGTGGGTAAGG
AGGCCAAGGAGTTCCTTGGCAGAACTCCGCAGCGTATCAGGGCCATCCGTCCCATGAAGGACGGAGTCATCGCTGATTTC
GAAGTGACCAAGCAGATGATAGCGTATTTCGTCCGCAAGGTTATTTCCGGGATGAGCATGGCCAAGCCCAGAATTGTCAT
CTGCGTGCCCACGGGGATAACGCAGGTGGAAAAGCGTGCGGTTATCGAATCTGCCCAGCAGGCAGGCGCACGCGATGTCA
AGCTGATAGAAGAACCCATGGCGGCGGCCATAGGCGCTGATATGCCCATTAACGAGCCGTTTGGCAGCATGGTTGTTGAT
ATCGGCGGCGGCACCACTGAAGTGGCGGTTATTTCACTTTCCGCCATAGCGTATGCAGAATCAGTGCGCGTCGCCGGCGA
TGCCATGAACCAGGCTGTGCAGCGGTTTATGCAGGAACGTTTCCAGCTGCTTATCGGCGAGAATATGTCCGAACGGATAA
AGATGACCGTGGGCTCGGCCTTTGAATTGCCCGAACCGCTTTCCATGAGTGTATCCGGTAAAGATATGGTTACCGGCACT
CCTAAAGCGGTCGAGGTGACTGACTCTGAAATCCGTGAGGCACTGCAGGACCCCGTGAAAGCTATAGTCATGGCCGTCCG
CAAGGCTCTTGAAAAAACTCCACCTGAGCTTGCAGGCGACATTGTGACACACGGTATTCTTCTGGCGGGAGGCGGTGCCC
TGCTCAAGGGGCTTGACCGCCTGATCACGGCAGAGACGGGACTGAAGGTCACCATAGATTCCGAGCCTCTTACCACGGTT
GTGCGGGGCACGGGCAGAACTCTGGATGATAAGAAATTTTACAGCAGAGTTTATGTCAACTAG

Upstream 100 bases:

>100_bases
GAAGCCAGCTGCACGATCTGGAAAACGAGCTCGGTCAGCAGCGTGCGGCCGGTTCCGGAGCACGCGAACCTTCTGATACC
ACCACCTCCGGGGATATATA

Downstream 100 bases:

>100_bases
CCTTGAATTATAACAAGATGAAGCGGCTGAAAGGCCGCTTTTTTTACGGGGCGCAGATGCAGCAGACAGAAGAATTATGT
GCAGCGGCAAAAAATGCGGT

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MFGKLFGFLGKDLAMDLGTANTLLYTRTEGIVLNEPSVVAIDQQRNTVLAVGKEAKEFLGRTPQRIRAIRPMKDGVIADF
EVTKQMIAYFVRKVISGMSMAKPRIVICVPTGITQVEKRAVIESAQQAGARDVKLIEEPMAAAIGADMPINEPFGSMVVD
IGGGTTEVAVISLSAIAYAESVRVAGDAMNQAVQRFMQERFQLLIGENMSERIKMTVGSAFELPEPLSMSVSGKDMVTGT
PKAVEVTDSEIREALQDPVKAIVMAVRKALEKTPPELAGDIVTHGILLAGGGALLKGLDRLITAETGLKVTIDSEPLTTV
VRGTGRTLDDKKFYSRVYVN

Sequences:

>Translated_340_residues
MFGKLFGFLGKDLAMDLGTANTLLYTRTEGIVLNEPSVVAIDQQRNTVLAVGKEAKEFLGRTPQRIRAIRPMKDGVIADF
EVTKQMIAYFVRKVISGMSMAKPRIVICVPTGITQVEKRAVIESAQQAGARDVKLIEEPMAAAIGADMPINEPFGSMVVD
IGGGTTEVAVISLSAIAYAESVRVAGDAMNQAVQRFMQERFQLLIGENMSERIKMTVGSAFELPEPLSMSVSGKDMVTGT
PKAVEVTDSEIREALQDPVKAIVMAVRKALEKTPPELAGDIVTHGILLAGGGALLKGLDRLITAETGLKVTIDSEPLTTV
VRGTGRTLDDKKFYSRVYVN
>Mature_340_residues
MFGKLFGFLGKDLAMDLGTANTLLYTRTEGIVLNEPSVVAIDQQRNTVLAVGKEAKEFLGRTPQRIRAIRPMKDGVIADF
EVTKQMIAYFVRKVISGMSMAKPRIVICVPTGITQVEKRAVIESAQQAGARDVKLIEEPMAAAIGADMPINEPFGSMVVD
IGGGTTEVAVISLSAIAYAESVRVAGDAMNQAVQRFMQERFQLLIGENMSERIKMTVGSAFELPEPLSMSVSGKDMVTGT
PKAVEVTDSEIREALQDPVKAIVMAVRKALEKTPPELAGDIVTHGILLAGGGALLKGLDRLITAETGLKVTIDSEPLTTV
VRGTGRTLDDKKFYSRVYVN

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=334, Percent_Identity=54.4910179640719, Blast_Score=355, Evalue=3e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36630; Mature: 36630

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGKLFGFLGKDLAMDLGTANTLLYTRTEGIVLNEPSVVAIDQQRNTVLAVGKEAKEFLG
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCCEEEEECCCCEEEEECHHHHHHHC
RTPQRIRAIRPMKDGVIADFEVTKQMIAYFVRKVISGMSMAKPRIVICVPTGITQVEKRA
CCHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHH
VIESAQQAGARDVKLIEEPMAAAIGADMPINEPFGSMVVDIGGGTTEVAVISLSAIAYAE
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEEEHHHHHHHH
SVRVAGDAMNQAVQRFMQERFQLLIGENMSERIKMTVGSAFELPEPLSMSVSGKDMVTGT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEHCCCCCCCCCCCCCCCCCCCCCCCC
PKAVEVTDSEIREALQDPVKAIVMAVRKALEKTPPELAGDIVTHGILLAGGGALLKGLDR
CCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCHHHHHHHHH
LITAETGLKVTIDSEPLTTVVRGTGRTLDDKKFYSRVYVN
HHHHCCCCEEEECCCCHHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MFGKLFGFLGKDLAMDLGTANTLLYTRTEGIVLNEPSVVAIDQQRNTVLAVGKEAKEFLG
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCCEEEEECCCCEEEEECHHHHHHHC
RTPQRIRAIRPMKDGVIADFEVTKQMIAYFVRKVISGMSMAKPRIVICVPTGITQVEKRA
CCHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHH
VIESAQQAGARDVKLIEEPMAAAIGADMPINEPFGSMVVDIGGGTTEVAVISLSAIAYAE
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEEEHHHHHHHH
SVRVAGDAMNQAVQRFMQERFQLLIGENMSERIKMTVGSAFELPEPLSMSVSGKDMVTGT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEHCCCCCCCCCCCCCCCCCCCCCCCC
PKAVEVTDSEIREALQDPVKAIVMAVRKALEKTPPELAGDIVTHGILLAGGGALLKGLDR
CCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCHHHHHHHHH
LITAETGLKVTIDSEPLTTVVRGTGRTLDDKKFYSRVYVN
HHHHCCCCEEEECCCCHHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]