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The map label for this gene is suhB [H]

Identifier: 78357035

GI number: 78357035

Start: 2034197

End: 2035000

Strand: Reverse

Name: suhB [H]

Synonym: Dde_1992

Alternate gene names: 78357035

Gene position: 2035000-2034197 (Counterclockwise)

Preceding gene: 78357036

Following gene: 78357033

Centisome position: 54.55

GC content: 59.45

Gene sequence:

>804_bases
ATGCAGCAGACAGAAGAATTATGTGCAGCGGCAAAAAATGCGGTGCGTGAGGCGGGCGGCATTATACTGGAACACTGGCA
TAAGCCCCGCACGATCAGGTTCAAAGGCAGGATCGATCTGGTGACAGCCACTGACCTCGCTGTGGAAGAGTTTCTGCGCA
ATGCGCTGAAACGCATTCTTCCCGATGCCGTTTTTCTGGGTGAAGAGACTTCTCCCGACGCTTCTCTGGGCAAATGGGCA
TGGATTCTGGATCCGGTGGACGGGACGACAAATTTTGCCCACGGGCTGCCTTTTGTAGCCACGTCACTGGGGCTGTGGCA
CGACGGAAAGGTTGTGGCGGGCATCGTGAATAACCCTGTGATGGGCGAATGCTTCTGGGCCGTGCGGGGCGCAGGGGCCT
GGCGGCAGTGCGGCGGTTCAGATGCCGCTCCTGTGCGGCTGGGGGTTACAACCACCGGTTCTCTGGCTGATGCGCTGGTG
GCCACCGGTTTTCCTTATTCGGTGGCGGAAGAAAGCGGGGATGTGCTGGCATGGCTGAAAAACAGCCTTGAACAATGCAG
AGGTGTGCGCCGTTATGGTGCCGCTGCGCTTGATCTTGCCTATCTGGCTGCCGGCCATTACGATATTTTTTATGAGCGCG
GACTGAAACCGTGGGACACCGCTGCCGGCTGGCTTCTGGTGGAGGAAGCGGGCGGGCGTGTCACTGCTTTTGACGGCCGG
AGTGCATATGCGTTTGATCCGCTGGGCATTCTGGCTACCAACGGGGTGCTGCACGGGGCCGCTGCCGGCCTGCTGGCGGT
ATAG

Upstream 100 bases:

>100_bases
CTCTGGATGATAAGAAATTTTACAGCAGAGTTTATGTCAACTAGCCTTGAATTATAACAAGATGAAGCGGCTGAAAGGCC
GCTTTTTTTACGGGGCGCAG

Downstream 100 bases:

>100_bases
TGGTGTTCATGCAGACCGTCGGAACAGAAAACCGTTGGTGTACGCCCAGTGGACAGCCGGAGTGAGCATTTCGCCGAAGT
GGTTGACAGTAGCATCGAGA

Product: inositol-1-monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MQQTEELCAAAKNAVREAGGIILEHWHKPRTIRFKGRIDLVTATDLAVEEFLRNALKRILPDAVFLGEETSPDASLGKWA
WILDPVDGTTNFAHGLPFVATSLGLWHDGKVVAGIVNNPVMGECFWAVRGAGAWRQCGGSDAAPVRLGVTTTGSLADALV
ATGFPYSVAEESGDVLAWLKNSLEQCRGVRRYGAAALDLAYLAAGHYDIFYERGLKPWDTAAGWLLVEEAGGRVTAFDGR
SAYAFDPLGILATNGVLHGAAAGLLAV

Sequences:

>Translated_267_residues
MQQTEELCAAAKNAVREAGGIILEHWHKPRTIRFKGRIDLVTATDLAVEEFLRNALKRILPDAVFLGEETSPDASLGKWA
WILDPVDGTTNFAHGLPFVATSLGLWHDGKVVAGIVNNPVMGECFWAVRGAGAWRQCGGSDAAPVRLGVTTTGSLADALV
ATGFPYSVAEESGDVLAWLKNSLEQCRGVRRYGAAALDLAYLAAGHYDIFYERGLKPWDTAAGWLLVEEAGGRVTAFDGR
SAYAFDPLGILATNGVLHGAAAGLLAV
>Mature_267_residues
MQQTEELCAAAKNAVREAGGIILEHWHKPRTIRFKGRIDLVTATDLAVEEFLRNALKRILPDAVFLGEETSPDASLGKWA
WILDPVDGTTNFAHGLPFVATSLGLWHDGKVVAGIVNNPVMGECFWAVRGAGAWRQCGGSDAAPVRLGVTTTGSLADALV
ATGFPYSVAEESGDVLAWLKNSLEQCRGVRRYGAAALDLAYLAAGHYDIFYERGLKPWDTAAGWLLVEEAGGRVTAFDGR
SAYAFDPLGILATNGVLHGAAAGLLAV

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=227, Percent_Identity=33.0396475770925, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI221625487, Length=238, Percent_Identity=32.3529411764706, Blast_Score=121, Evalue=5e-28,
Organism=Homo sapiens, GI7657236, Length=259, Percent_Identity=31.6602316602317, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI221625507, Length=130, Percent_Identity=37.6923076923077, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1788882, Length=240, Percent_Identity=36.6666666666667, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1790659, Length=147, Percent_Identity=29.2517006802721, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193202572, Length=228, Percent_Identity=32.0175438596491, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193202570, Length=235, Percent_Identity=32.3404255319149, Blast_Score=110, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6320493, Length=200, Percent_Identity=35, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321836, Length=235, Percent_Identity=30.2127659574468, Blast_Score=102, Evalue=9e-23,
Organism=Drosophila melanogaster, GI21357329, Length=237, Percent_Identity=35.4430379746835, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24664926, Length=259, Percent_Identity=31.6602316602317, Blast_Score=121, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24664922, Length=249, Percent_Identity=32.9317269076305, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21357957, Length=230, Percent_Identity=34.3478260869565, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24664918, Length=243, Percent_Identity=34.156378600823, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21357303, Length=230, Percent_Identity=33.4782608695652, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 28435; Mature: 28435

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQTEELCAAAKNAVREAGGIILEHWHKPRTIRFKGRIDLVTATDLAVEEFLRNALKRIL
CCHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECEEEEEEHHHHHHHHHHHHHHHHHC
PDAVFLGEETSPDASLGKWAWILDPVDGTTNFAHGLPFVATSLGLWHDGKVVAGIVNNPV
CCCEEECCCCCCCCCCCCEEEEEECCCCCCCHHCCCCHHHHHCCCCCCCCEEEEECCCCC
MGECFWAVRGAGAWRQCGGSDAAPVRLGVTTTGSLADALVATGFPYSVAEESGDVLAWLK
CHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCCCCHHHHCCCCCHHHHH
NSLEQCRGVRRYGAAALDLAYLAAGHYDIFYERGLKPWDTAAGWLLVEEAGGRVTAFDGR
HHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEEEECCCEEEEECCC
SAYAFDPLGILATNGVLHGAAAGLLAV
CCEEECCCHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MQQTEELCAAAKNAVREAGGIILEHWHKPRTIRFKGRIDLVTATDLAVEEFLRNALKRIL
CCHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECEEEEEEHHHHHHHHHHHHHHHHHC
PDAVFLGEETSPDASLGKWAWILDPVDGTTNFAHGLPFVATSLGLWHDGKVVAGIVNNPV
CCCEEECCCCCCCCCCCCEEEEEECCCCCCCHHCCCCHHHHHCCCCCCCCEEEEECCCCC
MGECFWAVRGAGAWRQCGGSDAAPVRLGVTTTGSLADALVATGFPYSVAEESGDVLAWLK
CHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCCCCHHHHCCCCCHHHHH
NSLEQCRGVRRYGAAALDLAYLAAGHYDIFYERGLKPWDTAAGWLLVEEAGGRVTAFDGR
HHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEEEECCCEEEEECCC
SAYAFDPLGILATNGVLHGAAAGLLAV
CCEEECCCHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]