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The map label for this gene is efp

Identifier: 78356996

GI number: 78356996

Start: 2002165

End: 2002722

Strand: Direct

Name: efp

Synonym: Dde_1953

Alternate gene names: 78356996

Gene position: 2002165-2002722 (Clockwise)

Preceding gene: 78356995

Following gene: 78356997

Centisome position: 53.67

GC content: 52.87

Gene sequence:

>558_bases
ATGTATTCCACTACCGATTTCAGACGCGGCCTGCGTATCGAAATTGACGGCACCCCTTTTGAAATTGTCGACTTCCAGCA
CTTCAAGCCCGGCAAAGGCGGGGCCATTGTGCGTACCAAAATGCGCAACCTGCTCACCGGCCGCATTATGGACAACAACT
TCCGTTCCGGCGAAAAAGTAGGCCGTCCCGACATGGAAAACCGCGACATGCAGTTTCTGTATCGTGAAGACGCCAATCTT
GTTTTCATGGACATGACGACCTATGAGCAGATTTACATGCCGGAAGAAACCACGGAAGGCAAAGCAGGATTCCTTAAGGA
AGGGCAAACCATCCGCGTACTGCTGTTCAACGGCACGCCGCTGGCCATCGAACTGCCTGCAGCGCTGGTGCTCGAAGTGA
CCGAAACAGAACCCGGTGCAAAAGGCGACACCGTCTCCAACGTGACCAAGCCGGCAACCCTTGAAACCGGTATCGTCATT
CAGGTTCCTATTTTTGTGAACCAGGGAGACAAGGTTAAAGTAAACACGGACACCCGTGAATACATGGGACGGGAATAG

Upstream 100 bases:

>100_bases
CCTGGGCGTGCAGGCGCTTGTAACGCACCTGCAGGACACTCAACAGTAAACTGGCATCACAGGCCTGCGGGCTTTATATC
AACTTTTTCGGAGGCATCCC

Downstream 100 bases:

>100_bases
CCCCCGGCGTCCTGTCCCGCCGGCGTTATTGCCCGCGGCTATGGACGCAGCATTTTGATTACGGTAAGGGATATGGCTGA
AGAGGCTGTATCCCTTCTTT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MYSTTDFRRGLRIEIDGTPFEIVDFQHFKPGKGGAIVRTKMRNLLTGRIMDNNFRSGEKVGRPDMENRDMQFLYREDANL
VFMDMTTYEQIYMPEETTEGKAGFLKEGQTIRVLLFNGTPLAIELPAALVLEVTETEPGAKGDTVSNVTKPATLETGIVI
QVPIFVNQGDKVKVNTDTREYMGRE

Sequences:

>Translated_185_residues
MYSTTDFRRGLRIEIDGTPFEIVDFQHFKPGKGGAIVRTKMRNLLTGRIMDNNFRSGEKVGRPDMENRDMQFLYREDANL
VFMDMTTYEQIYMPEETTEGKAGFLKEGQTIRVLLFNGTPLAIELPAALVLEVTETEPGAKGDTVSNVTKPATLETGIVI
QVPIFVNQGDKVKVNTDTREYMGRE
>Mature_185_residues
MYSTTDFRRGLRIEIDGTPFEIVDFQHFKPGKGGAIVRTKMRNLLTGRIMDNNFRSGEKVGRPDMENRDMQFLYREDANL
VFMDMTTYEQIYMPEETTEGKAGFLKEGQTIRVLLFNGTPLAIELPAALVLEVTETEPGAKGDTVSNVTKPATLETGIVI
QVPIFVNQGDKVKVNTDTREYMGRE

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=183, Percent_Identity=37.7049180327869, Blast_Score=136, Evalue=8e-34,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=32.9787234042553, Blast_Score=100, Evalue=5e-23,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_DESDG (Q30ZZ6)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388445.1
- ProteinModelPortal:   Q30ZZ6
- SMR:   Q30ZZ6
- STRING:   Q30ZZ6
- GeneID:   3756959
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1953
- NMPDR:   fig|207559.3.peg.1286
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   DDES207559:DDE_1953-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20891; Mature: 20891

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSTTDFRRGLRIEIDGTPFEIVDFQHFKPGKGGAIVRTKMRNLLTGRIMDNNFRSGEKV
CCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCEEEHHHHHHHHCCEEECCCCCCCCCC
GRPDMENRDMQFLYREDANLVFMDMTTYEQIYMPEETTEGKAGFLKEGQTIRVLLFNGTP
CCCCCCCCCEEEEEECCCCEEEEEECCCEEEECCCCCCCCCCCEECCCCEEEEEEECCCC
LAIELPAALVLEVTETEPGAKGDTVSNVTKPATLETGIVIQVPIFVNQGDKVKVNTDTRE
EEEECCCEEEEEEECCCCCCCCCCCCCCCCCCEECCCEEEEEEEEECCCCEEEEECCHHH
YMGRE
HCCCC
>Mature Secondary Structure
MYSTTDFRRGLRIEIDGTPFEIVDFQHFKPGKGGAIVRTKMRNLLTGRIMDNNFRSGEKV
CCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCEEEHHHHHHHHCCEEECCCCCCCCCC
GRPDMENRDMQFLYREDANLVFMDMTTYEQIYMPEETTEGKAGFLKEGQTIRVLLFNGTP
CCCCCCCCCEEEEEECCCCEEEEEECCCEEEECCCCCCCCCCCEECCCCEEEEEEECCCC
LAIELPAALVLEVTETEPGAKGDTVSNVTKPATLETGIVIQVPIFVNQGDKVKVNTDTRE
EEEECCCEEEEEEECCCCCCCCCCCCCCCCCCEECCCEEEEEEEEECCCCEEEEECCHHH
YMGRE
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA