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The map label for this gene is aroQ [H]

Identifier: 78356995

GI number: 78356995

Start: 2001649

End: 2002113

Strand: Direct

Name: aroQ [H]

Synonym: Dde_1952

Alternate gene names: 78356995

Gene position: 2001649-2002113 (Clockwise)

Preceding gene: 78356994

Following gene: 78356996

Centisome position: 53.66

GC content: 56.99

Gene sequence:

>465_bases
GTGAACCGTTTCAGAATTCTCGTGATGAACGGGCCGAACCTCGGCCATCTGGGTCAGAGACAGCCGGAAATCTATGGCAG
CACGGGCATGGACGCTCTTCCCGGTATGTTAAAGCGCCTGATGGGCGAGCAGGCAGAAGCGCTGGAACTGGAATATTTTC
ACAGTAACAGCGAAGGGGCTCTTATCGACAGGCTCGAACTGGCACGACAGGACGGAACAGCCGGAGTTGTTCTGAACGCA
GGAGCTTATACACACACAAGCCTTGCGCTGGCAGACTGTCTGGCATGGATAAACCTGCCGTGCGTGGAAGTGCACATAAG
CAATGTTCTGGCACGGGCAGAGCAGCTGCGTCACCGCAGCCTCATCGGCCGTCATGTCATCGGCGTTGTGGCCGGTTTTG
GCATGGCAAGCTATGCCCTGGGCGTGCAGGCGCTTGTAACGCACCTGCAGGACACTCAACAGTAA

Upstream 100 bases:

>100_bases
AGATAATGACCTTGGGAAAAAATACTCCGCTTTTCGCAGGGCACCTTCTGTCAATGAATGCTAGCAGAACCGGCTTGCAA
AAACAAAGAGGTTTTTTGCC

Downstream 100 bases:

>100_bases
ACTGGCATCACAGGCCTGCGGGCTTTATATCAACTTTTTCGGAGGCATCCCATGTATTCCACTACCGATTTCAGACGCGG
CCTGCGTATCGAAATTGACG

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MNRFRILVMNGPNLGHLGQRQPEIYGSTGMDALPGMLKRLMGEQAEALELEYFHSNSEGALIDRLELARQDGTAGVVLNA
GAYTHTSLALADCLAWINLPCVEVHISNVLARAEQLRHRSLIGRHVIGVVAGFGMASYALGVQALVTHLQDTQQ

Sequences:

>Translated_154_residues
MNRFRILVMNGPNLGHLGQRQPEIYGSTGMDALPGMLKRLMGEQAEALELEYFHSNSEGALIDRLELARQDGTAGVVLNA
GAYTHTSLALADCLAWINLPCVEVHISNVLARAEQLRHRSLIGRHVIGVVAGFGMASYALGVQALVTHLQDTQQ
>Mature_154_residues
MNRFRILVMNGPNLGHLGQRQPEIYGSTGMDALPGMLKRLMGEQAEALELEYFHSNSEGALIDRLELARQDGTAGVVLNA
GAYTHTSLALADCLAWINLPCVEVHISNVLARAEQLRHRSLIGRHVIGVVAGFGMASYALGVQALVTHLQDTQQ

Specific function: Catalyzes a trans-dehydration via an enolate intermediate [H]

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001874
- InterPro:   IPR018509
- ProDom:   PD004527 [H]

Pfam domain/function: PF01220 DHquinase_II [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 16730; Mature: 16730

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFRILVMNGPNLGHLGQRQPEIYGSTGMDALPGMLKRLMGEQAEALELEYFHSNSEGA
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHEEEEEEECCCCCH
LIDRLELARQDGTAGVVLNAGAYTHTSLALADCLAWINLPCVEVHISNVLARAEQLRHRS
HHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LIGRHVIGVVAGFGMASYALGVQALVTHLQDTQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNRFRILVMNGPNLGHLGQRQPEIYGSTGMDALPGMLKRLMGEQAEALELEYFHSNSEGA
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHEEEEEEECCCCCH
LIDRLELARQDGTAGVVLNAGAYTHTSLALADCLAWINLPCVEVHISNVLARAEQLRHRS
HHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LIGRHVIGVVAGFGMASYALGVQALVTHLQDTQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]