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The map label for this gene is nadA [H]

Identifier: 78356873

GI number: 78356873

Start: 1879165

End: 1880205

Strand: Reverse

Name: nadA [H]

Synonym: Dde_1830

Alternate gene names: 78356873

Gene position: 1880205-1879165 (Counterclockwise)

Preceding gene: 78356874

Following gene: 78356872

Centisome position: 50.4

GC content: 56.58

Gene sequence:

>1041_bases
ATGAATACACAAAACAGCTATGACACCATTCAGGAGATCAGGTCCCGTATGGGCAGCCGCCTGACCATTATGGGACACCA
CTACCAGCACGAAACCGTAATCCGGCACACTGAGCTGCGGGGCGACTCGCTGGAACTGGCCCGCAAGACATCTCAGGTTG
ATGCGGAACATATTGTTTTCTGCGGGGTGTATTTCATGGGAGAATCGTCTGCCCTGCTGGCCCGCCACGGTCAGAAAATT
TATCTGCCCGAGCCGGATGCGAACTGTGTCATGTCGCAGATGGCTCCCGCAGAAAGGGTCGACCGGGTACTCACCGCGCT
TTCCGGTCGTGGCAGACGCATTGTACCTCTTACTTATGTCAATTCATCGGTGGCTGTGAAAGCCGTGGTGGGCAGACATG
GCGGTTCGGTGTGCACGTCGGCCAATGCCCGTACAATGCTTGAATGGGCGTTTGCACAGGGCGATGCGGTGCTTTTTATT
CCTGACAAGAATCTGGCGGCAAACACAGCGGATGCTCTGCAGATTCCTTTTGAAAAACGCCATATTCTTAATATCCGCCA
AAACGGGGCTGCCATCGACTTTGACGCGGCGGACAGGGCTGACCTGTTGATGTGGCCGGGCTGCTGTGCCATTCATGCCC
GCTTCAATCTGCGGCAGATCGCCACAATGCGCGAAGCCCATCCCGGATGCCGCATCGTGGTGCACCCCGAATGCAGCCCC
GATGTGGTCAGACAGGCCGATGCCGCAGGGTCAACGTCTTTCATAATCAGATACACCGAAGAGGCGCCCGAAGGTTCCAC
TGTAGTTGTGGGTACCGAAATCAATCTGGTGGAAAGGCTGGCAGCGCAATATGCCGGCCGCAAGACCGTGCTGCCGCTGC
TTGAAAGTGCGTGTTCACACATGAACAGCGTCACTGAAGAAAAGCTGGCGGCAACGCTGACCGCAGTTGAAAACGGCACA
TGTGCGCCGGTTATGGTTCCCCTAGAAATGCAGGACAACGCCCGTGTTGCCCTGGAGCGCATGCTGCAGGCCTGCGCATA
A

Upstream 100 bases:

>100_bases
GGCGCAGGCCTCCTCTCGACGGCTTGATTTTATTTCCGTGGGCAGGCTGACTCATTCCGCCCCTTCCGCAGATTTCAGCA
TGCGTATAAGCGAGTAGCAA

Downstream 100 bases:

>100_bases
AAAGAGGCACTTTTATGTCCACTTTCCGTCCCGTCACTCCTGTTCTGGTCATCGGATCCGGTATTGCCGGATGCACTGCG
GCTCTTACTCTGGCCGACAT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MNTQNSYDTIQEIRSRMGSRLTIMGHHYQHETVIRHTELRGDSLELARKTSQVDAEHIVFCGVYFMGESSALLARHGQKI
YLPEPDANCVMSQMAPAERVDRVLTALSGRGRRIVPLTYVNSSVAVKAVVGRHGGSVCTSANARTMLEWAFAQGDAVLFI
PDKNLAANTADALQIPFEKRHILNIRQNGAAIDFDAADRADLLMWPGCCAIHARFNLRQIATMREAHPGCRIVVHPECSP
DVVRQADAAGSTSFIIRYTEEAPEGSTVVVGTEINLVERLAAQYAGRKTVLPLLESACSHMNSVTEEKLAATLTAVENGT
CAPVMVPLEMQDNARVALERMLQACA

Sequences:

>Translated_346_residues
MNTQNSYDTIQEIRSRMGSRLTIMGHHYQHETVIRHTELRGDSLELARKTSQVDAEHIVFCGVYFMGESSALLARHGQKI
YLPEPDANCVMSQMAPAERVDRVLTALSGRGRRIVPLTYVNSSVAVKAVVGRHGGSVCTSANARTMLEWAFAQGDAVLFI
PDKNLAANTADALQIPFEKRHILNIRQNGAAIDFDAADRADLLMWPGCCAIHARFNLRQIATMREAHPGCRIVVHPECSP
DVVRQADAAGSTSFIIRYTEEAPEGSTVVVGTEINLVERLAAQYAGRKTVLPLLESACSHMNSVTEEKLAATLTAVENGT
CAPVMVPLEMQDNARVALERMLQACA
>Mature_346_residues
MNTQNSYDTIQEIRSRMGSRLTIMGHHYQHETVIRHTELRGDSLELARKTSQVDAEHIVFCGVYFMGESSALLARHGQKI
YLPEPDANCVMSQMAPAERVDRVLTALSGRGRRIVPLTYVNSSVAVKAVVGRHGGSVCTSANARTMLEWAFAQGDAVLFI
PDKNLAANTADALQIPFEKRHILNIRQNGAAIDFDAADRADLLMWPGCCAIHARFNLRQIATMREAHPGCRIVVHPECSP
DVVRQADAAGSTSFIIRYTEEAPEGSTVVVGTEINLVERLAAQYAGRKTVLPLLESACSHMNSVTEEKLAATLTAVENGT
CAPVMVPLEMQDNARVALERMLQACA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=352, Percent_Identity=26.4204545454545, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 37868; Mature: 37868

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTQNSYDTIQEIRSRMGSRLTIMGHHYQHETVIRHTELRGDSLELARKTSQVDAEHIVF
CCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHEEHHHCCCCHHHHHHHHHHCCCCEEEE
CGVYFMGESSALLARHGQKIYLPEPDANCVMSQMAPAERVDRVLTALSGRGRRIVPLTYV
EEEEEECCCCHHHHHCCCEEECCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEE
NSSVAVKAVVGRHGGSVCTSANARTMLEWAFAQGDAVLFIPDKNLAANTADALQIPFEKR
CCCEEEEEEECCCCCCEECCCCCHHEEEEHCCCCCEEEEEECCCCCCCCCCCEECCCCCC
HILNIRQNGAAIDFDAADRADLLMWPGCCAIHARFNLRQIATMREAHPGCRIVVHPECSP
EEEEEECCCCEEEECCCCCCCEEECCCCEEEEECCCHHHHHHHHHCCCCCEEEECCCCCH
DVVRQADAAGSTSFIIRYTEEAPEGSTVVVGTEINLVERLAAQYAGRKTVLPLLESACSH
HHHHHHCCCCCCEEEEEEECCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHH
MNSVTEEKLAATLTAVENGTCAPVMVPLEMQDNARVALERMLQACA
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNTQNSYDTIQEIRSRMGSRLTIMGHHYQHETVIRHTELRGDSLELARKTSQVDAEHIVF
CCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHEEHHHCCCCHHHHHHHHHHCCCCEEEE
CGVYFMGESSALLARHGQKIYLPEPDANCVMSQMAPAERVDRVLTALSGRGRRIVPLTYV
EEEEEECCCCHHHHHCCCEEECCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEE
NSSVAVKAVVGRHGGSVCTSANARTMLEWAFAQGDAVLFIPDKNLAANTADALQIPFEKR
CCCEEEEEEECCCCCCEECCCCCHHEEEEHCCCCCEEEEEECCCCCCCCCCCEECCCCCC
HILNIRQNGAAIDFDAADRADLLMWPGCCAIHARFNLRQIATMREAHPGCRIVVHPECSP
EEEEEECCCCEEEECCCCCCCEEECCCCEEEEECCCHHHHHHHHHCCCCCEEEECCCCCH
DVVRQADAAGSTSFIIRYTEEAPEGSTVVVGTEINLVERLAAQYAGRKTVLPLLESACSH
HHHHHHCCCCCCEEEEEEECCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHH
MNSVTEEKLAATLTAVENGTCAPVMVPLEMQDNARVALERMLQACA
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA