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The map label for this gene is ctaD [H]

Identifier: 78356866

GI number: 78356866

Start: 1872443

End: 1874074

Strand: Direct

Name: ctaD [H]

Synonym: Dde_1823

Alternate gene names: 78356866

Gene position: 1872443-1874074 (Clockwise)

Preceding gene: 78356865

Following gene: 78356867

Centisome position: 50.2

GC content: 52.7

Gene sequence:

>1632_bases
ATGGCTACGGCTGACGCGGTTCAGACTTCCCGGGGCTTCTGGGGACCGTTGCAGGGCACAAAAAACAGCATCGGTTCATG
GATTTTTTCAACAGACCACAAACGTATCGGCATACTGTATTTCTATGGTATAATAGGATTTTTCCTCGTGGGGCTGCTTC
TTGGCTTTCTTGTACGCCTTGAGCTTATCGCCCCCGGAAAAACCATCATGGACGCGCAGACATACAATGCCATATTCACG
CTGCATGGCGTGGTCATGATTTTTCTGGTGGTCATCCCCAGCATTCCGGCCGCATTCGGCAATATCTTTCTTCCCATTCA
GATAGGGGCCGAGGATGTCTCCTTTCCCCGCCTGAACAATTTTTCATGGTGGCTTTATGTCACCGGTGCAGTGCTCGCGC
TCAGCTCTCTCTTTACGGGTGACGGTCCGCCGGACACGGGCTGGACGTTTTACGTCCCCTTCAGCAACGTGACCACCACA
AACGTCAACGTGGCTCTTGCAGCCGTATTTGTTCTGGGTTTTTCTTCCATACTCACCGGCCTCAATTTCATCACCACCAT
CCACCGATTGCGGGCCGAGGGCATGACATGGACCCGGCTGCCTCTTTTTGTCTGGTCGCTGTATGCCACCGGCTGGATTC
AGGTACTCGCCACTCCGGTGCTTGGTATCACCGTGCTGCTGGTTGTGGTTGAAAGGGTAATGGGGGTGGGGCTGTTTGAC
GCCACCAAAGGCGGCGACCCGCTGCTGTATCAGCACCTTTTCTGGATATATTCACACCCGGCCGTGTACATAATGATTCT
GCCCGCCATGGGTGTAATTTCCGAAATAATTCCGGTATTTTCCCGCAAGAAAATCTTCGGCTACAAGATGATCGCTTTTT
CCAGCCTTGCCATAGCCTTTGCGGGTTCACTGGTATGGGCGCATCATATGTTCACCAGCGGCATGAGCGATACCGCAGTG
CTGGTTTTTTCGTTTCTCACATTTGTCGTCGCCATTCCTTCTGCCATCAAGGTGTTCAACTGGGTTTCCACCATGTTCAA
GGGGTCCATCTATCTTGAACCGCCCATGTACTACGCCATGGCGTTCATCTTTCTCTTTTCCATAGGTGGGCTTACCGGAC
TGGTGCTGGGCGGGGCCGGAACTGATATCCATGTGCATGATACATATTTTGTTGTCGCGCACTTCCATTATGTCATTTTC
GGCGGGCTCGGGTTCGGTCTGTTCGGAGCCATGCATTACTGGTTCCCCAAAATATACGGAAAGATGTATAACAAAAGAGT
GGCCAACATCTCCTGTCTGGTTACTTTCATCGGTTTCAACGTTCTGTACTTTCCGCTTTTCGTCATCGGCCTGCAGGGCA
TGCCGCGCAGATATTACGACTATCTGCCGCAGTACACCACGGGGCATTTCATTTCCACAGTAGGATCCTGGATTCTGGCC
GCAGGGCTTCTGCTCATGCTGTGGAATCTGTTCAAGGGAGCACGCAGCGGCCCCCGGGCCGGTGACAATCCTTGGAACGC
CGTGACATTGGAATGGCAGGTTCCTTCTCCTCCCCCGCATCACAACTTTGTTGAAGAACCTGTGGTCACACACGGGCCGT
ACGACTTCAGGGAGGTGACTTCCGATGAGTAA

Upstream 100 bases:

>100_bases
GGCATAGCTTTGTTCCTCTTTCTTCTTTTGCGCGGCGGGAAAAAAAGAAACTGACTTAGCGGCACAACAATAAGCTTAAC
GTCCCAAGTGAGAGGTGGTT

Downstream 100 bases:

>100_bases
CGTCCATAACGACTATCTGGGCGCCAAAATAGGCATGTGGCTGTTCCTGTTTACAGAAGTCCTTCTCTTCGGCGGATTGT
TCCTGCTGTATGCCATCTAC

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MATADAVQTSRGFWGPLQGTKNSIGSWIFSTDHKRIGILYFYGIIGFFLVGLLLGFLVRLELIAPGKTIMDAQTYNAIFT
LHGVVMIFLVVIPSIPAAFGNIFLPIQIGAEDVSFPRLNNFSWWLYVTGAVLALSSLFTGDGPPDTGWTFYVPFSNVTTT
NVNVALAAVFVLGFSSILTGLNFITTIHRLRAEGMTWTRLPLFVWSLYATGWIQVLATPVLGITVLLVVVERVMGVGLFD
ATKGGDPLLYQHLFWIYSHPAVYIMILPAMGVISEIIPVFSRKKIFGYKMIAFSSLAIAFAGSLVWAHHMFTSGMSDTAV
LVFSFLTFVVAIPSAIKVFNWVSTMFKGSIYLEPPMYYAMAFIFLFSIGGLTGLVLGGAGTDIHVHDTYFVVAHFHYVIF
GGLGFGLFGAMHYWFPKIYGKMYNKRVANISCLVTFIGFNVLYFPLFVIGLQGMPRRYYDYLPQYTTGHFISTVGSWILA
AGLLLMLWNLFKGARSGPRAGDNPWNAVTLEWQVPSPPPHHNFVEEPVVTHGPYDFREVTSDE

Sequences:

>Translated_543_residues
MATADAVQTSRGFWGPLQGTKNSIGSWIFSTDHKRIGILYFYGIIGFFLVGLLLGFLVRLELIAPGKTIMDAQTYNAIFT
LHGVVMIFLVVIPSIPAAFGNIFLPIQIGAEDVSFPRLNNFSWWLYVTGAVLALSSLFTGDGPPDTGWTFYVPFSNVTTT
NVNVALAAVFVLGFSSILTGLNFITTIHRLRAEGMTWTRLPLFVWSLYATGWIQVLATPVLGITVLLVVVERVMGVGLFD
ATKGGDPLLYQHLFWIYSHPAVYIMILPAMGVISEIIPVFSRKKIFGYKMIAFSSLAIAFAGSLVWAHHMFTSGMSDTAV
LVFSFLTFVVAIPSAIKVFNWVSTMFKGSIYLEPPMYYAMAFIFLFSIGGLTGLVLGGAGTDIHVHDTYFVVAHFHYVIF
GGLGFGLFGAMHYWFPKIYGKMYNKRVANISCLVTFIGFNVLYFPLFVIGLQGMPRRYYDYLPQYTTGHFISTVGSWILA
AGLLLMLWNLFKGARSGPRAGDNPWNAVTLEWQVPSPPPHHNFVEEPVVTHGPYDFREVTSDE
>Mature_542_residues
ATADAVQTSRGFWGPLQGTKNSIGSWIFSTDHKRIGILYFYGIIGFFLVGLLLGFLVRLELIAPGKTIMDAQTYNAIFTL
HGVVMIFLVVIPSIPAAFGNIFLPIQIGAEDVSFPRLNNFSWWLYVTGAVLALSSLFTGDGPPDTGWTFYVPFSNVTTTN
VNVALAAVFVLGFSSILTGLNFITTIHRLRAEGMTWTRLPLFVWSLYATGWIQVLATPVLGITVLLVVVERVMGVGLFDA
TKGGDPLLYQHLFWIYSHPAVYIMILPAMGVISEIIPVFSRKKIFGYKMIAFSSLAIAFAGSLVWAHHMFTSGMSDTAVL
VFSFLTFVVAIPSAIKVFNWVSTMFKGSIYLEPPMYYAMAFIFLFSIGGLTGLVLGGAGTDIHVHDTYFVVAHFHYVIFG
GLGFGLFGAMHYWFPKIYGKMYNKRVANISCLVTFIGFNVLYFPLFVIGLQGMPRRYYDYLPQYTTGHFISTVGSWILAA
GLLLMLWNLFKGARSGPRAGDNPWNAVTLEWQVPSPPPHHNFVEEPVVTHGPYDFREVTSDE

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=506, Percent_Identity=41.304347826087, Blast_Score=363, Evalue=1e-100,
Organism=Escherichia coli, GI1786634, Length=527, Percent_Identity=37.0018975332068, Blast_Score=343, Evalue=2e-95,
Organism=Saccharomyces cerevisiae, GI6226519, Length=527, Percent_Identity=37.7609108159393, Blast_Score=371, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6226524, Length=328, Percent_Identity=37.5, Blast_Score=238, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6226523, Length=248, Percent_Identity=35.8870967741936, Blast_Score=153, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 60250; Mature: 60119

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATADAVQTSRGFWGPLQGTKNSIGSWIFSTDHKRIGILYFYGIIGFFLVGLLLGFLVRL
CCCCHHHHHCCCCCCCCCCCHHHHCCCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
ELIAPGKTIMDAQTYNAIFTLHGVVMIFLVVIPSIPAAFGNIFLPIQIGAEDVSFPRLNN
HHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEEECCCCCCCCCCCC
FSWWLYVTGAVLALSSLFTGDGPPDTGWTFYVPFSNVTTTNVNVALAAVFVLGFSSILTG
CEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEECCHHHHHHHHHHHHHHHHHHH
LNFITTIHRLRAEGMTWTRLPLFVWSLYATGWIQVLATPVLGITVLLVVVERVMGVGLFD
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
ATKGGDPLLYQHLFWIYSHPAVYIMILPAMGVISEIIPVFSRKKIFGYKMIAFSSLAIAF
CCCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AGSLVWAHHMFTSGMSDTAVLVFSFLTFVVAIPSAIKVFNWVSTMFKGSIYLEPPMYYAM
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHH
AFIFLFSIGGLTGLVLGGAGTDIHVHDTYFVVAHFHYVIFGGLGFGLFGAMHYWFPKIYG
HHHHHHHHCCHHHEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMYNKRVANISCLVTFIGFNVLYFPLFVIGLQGMPRRYYDYLPQYTTGHFISTVGSWILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHH
AGLLLMLWNLFKGARSGPRAGDNPWNAVTLEWQVPSPPPHHNFVEEPVVTHGPYDFREVT
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHCC
SDE
CCC
>Mature Secondary Structure 
ATADAVQTSRGFWGPLQGTKNSIGSWIFSTDHKRIGILYFYGIIGFFLVGLLLGFLVRL
CCCHHHHHCCCCCCCCCCCHHHHCCCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
ELIAPGKTIMDAQTYNAIFTLHGVVMIFLVVIPSIPAAFGNIFLPIQIGAEDVSFPRLNN
HHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEEECCCCCCCCCCCC
FSWWLYVTGAVLALSSLFTGDGPPDTGWTFYVPFSNVTTTNVNVALAAVFVLGFSSILTG
CEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEECCHHHHHHHHHHHHHHHHHHH
LNFITTIHRLRAEGMTWTRLPLFVWSLYATGWIQVLATPVLGITVLLVVVERVMGVGLFD
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
ATKGGDPLLYQHLFWIYSHPAVYIMILPAMGVISEIIPVFSRKKIFGYKMIAFSSLAIAF
CCCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AGSLVWAHHMFTSGMSDTAVLVFSFLTFVVAIPSAIKVFNWVSTMFKGSIYLEPPMYYAM
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHH
AFIFLFSIGGLTGLVLGGAGTDIHVHDTYFVVAHFHYVIFGGLGFGLFGAMHYWFPKIYG
HHHHHHHHCCHHHEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMYNKRVANISCLVTFIGFNVLYFPLFVIGLQGMPRRYYDYLPQYTTGHFISTVGSWILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHH
AGLLLMLWNLFKGARSGPRAGDNPWNAVTLEWQVPSPPPHHNFVEEPVVTHGPYDFREVT
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHCC
SDE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8387368; 8905231 [H]