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The map label for this gene is tadA [H]

Identifier: 78356822

GI number: 78356822

Start: 1831590

End: 1832108

Strand: Reverse

Name: tadA [H]

Synonym: Dde_1779

Alternate gene names: 78356822

Gene position: 1832108-1831590 (Counterclockwise)

Preceding gene: 78356823

Following gene: 78356807

Centisome position: 49.12

GC content: 59.34

Gene sequence:

>519_bases
ATGTCATTATCTGACAACGGCATGAAGCAGAAGATGCAGATCATTCCTCCTGTGCCTTCCGGCTGGAAAAGCTGGGAGGC
ACTGATGGAGCTGGCTCTGGAACAGGCTGTGCTGGCGCAGCTGCACGGGGAAGTGCCCGTGGGTGCCGTGGTGGTCGCAC
CGGACGGAGCAGTGCTCGGCTCCGGACGCAACAGGCCCATTGCCACCTGTGACCCCACGGCGCACGCGGAAATCCTTGCC
ATACGTCAGGCGTGCATCCATACGGGCAACTACCGGCTGGACGATGCCGTACTGGTCGTGACGCTTGAGCCTTGCCACAT
GTGCACAGGCGCCATCATTCACGCCCGACTTGCAGGAGTGGTTTACGGGGCATCGGACAAGCGTGCCGGAGCGGTGGATT
CCTGCCTGGACGGGTTGGAGCTGCCTTTTCACAACCACAGGCCGTGGTATATGAGCGGTGTGTGCGAAGCTGAATGCTCG
CGGCTTCTTGCAGAGTTTTTTAAAGAAAAAAGACAGTGA

Upstream 100 bases:

>100_bases
CGGGACAAAATGGTGTCTGAAGGATTTATAAGAGAAGAAGAGCTTGATCTTATTACGGTCAAGGATACGCCGGAAGAGGT
GCTCGCCTACATCAAGCGAC

Downstream 100 bases:

>100_bases
CAGGCCGTCTGCCGGTTTTATGCCGCCGGTTTGCTGTTCTGCACAGCGGGTGCAGCGCAGGCGCTTTTGCCGGTGATGTC
TGCCTGTGCGCGGCACGGGC

Product: tRNA-adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MSLSDNGMKQKMQIIPPVPSGWKSWEALMELALEQAVLAQLHGEVPVGAVVVAPDGAVLGSGRNRPIATCDPTAHAEILA
IRQACIHTGNYRLDDAVLVVTLEPCHMCTGAIIHARLAGVVYGASDKRAGAVDSCLDGLELPFHNHRPWYMSGVCEAECS
RLLAEFFKEKRQ

Sequences:

>Translated_172_residues
MSLSDNGMKQKMQIIPPVPSGWKSWEALMELALEQAVLAQLHGEVPVGAVVVAPDGAVLGSGRNRPIATCDPTAHAEILA
IRQACIHTGNYRLDDAVLVVTLEPCHMCTGAIIHARLAGVVYGASDKRAGAVDSCLDGLELPFHNHRPWYMSGVCEAECS
RLLAEFFKEKRQ
>Mature_171_residues
SLSDNGMKQKMQIIPPVPSGWKSWEALMELALEQAVLAQLHGEVPVGAVVVAPDGAVLGSGRNRPIATCDPTAHAEILAI
RQACIHTGNYRLDDAVLVVTLEPCHMCTGAIIHARLAGVVYGASDKRAGAVDSCLDGLELPFHNHRPWYMSGVCEAECSR
LLAEFFKEKRQ

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=154, Percent_Identity=35.0649350649351, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI145693172, Length=149, Percent_Identity=51.006711409396, Blast_Score=137, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17554608, Length=106, Percent_Identity=41.5094339622642, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17541138, Length=111, Percent_Identity=41.4414414414414, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555996, Length=87, Percent_Identity=40.2298850574713, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6325319, Length=152, Percent_Identity=29.6052631578947, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 18586; Mature: 18454

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSDNGMKQKMQIIPPVPSGWKSWEALMELALEQAVLAQLHGEVPVGAVVVAPDGAVLG
CCCCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEC
SGRNRPIATCDPTAHAEILAIRQACIHTGNYRLDDAVLVVTLEPCHMCTGAIIHARLAGV
CCCCCCCEECCCCCHHHHHHHHHHHHHCCCCEECCEEEEEEECCHHHHHHHHHHHHHHHH
VYGASDKRAGAVDSCLDGLELPFHNHRPWYMSGVCEAECSRLLAEFFKEKRQ
EECCCCCCCCCHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLSDNGMKQKMQIIPPVPSGWKSWEALMELALEQAVLAQLHGEVPVGAVVVAPDGAVLG
CCCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEC
SGRNRPIATCDPTAHAEILAIRQACIHTGNYRLDDAVLVVTLEPCHMCTGAIIHARLAGV
CCCCCCCEECCCCCHHHHHHHHHHHHHCCCCEECCEEEEEEECCHHHHHHHHHHHHHHHH
VYGASDKRAGAVDSCLDGLELPFHNHRPWYMSGVCEAECSRLLAEFFKEKRQ
EECCCCCCCCCHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]