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The map label for this gene is purQ [H]

Identifier: 78356807

GI number: 78356807

Start: 1818948

End: 1819757

Strand: Reverse

Name: purQ [H]

Synonym: Dde_1764

Alternate gene names: 78356807

Gene position: 1819757-1818948 (Counterclockwise)

Preceding gene: 78356822

Following gene: 78356806

Centisome position: 48.78

GC content: 55.68

Gene sequence:

>810_bases
ATGACCAAGGTGAATACGCTGGTTATAACCGGCTACGGGACTAACTGCGAAGTTGAATGCGCGCACGCTGCGCGTATTGC
AGGAGCCGATGCCGTCGAAATAGCCCATTTTTCCGATCTTGAAACCGGCAGAATCCGCCTTGAGGATTTTAATTTTCTTA
TTTTCCCCGGCGGCTTTCTTGATGGTGACGATCTGGGAGCGGCTCAGGCAGCAGCGCAGCGCTGGAGACACGCCCAGACC
AAGGACGGCACCCCACTGCTGGACCAGCTGAAAAACTTCTTTGACCGCGGCGGGCTGATCATGGGCATCTGCAACGGCTT
CCAGTTGCTTGTCAAACTGGGACTGCTGCCCGCTCTCGATTCGATGTATTTCGAACGGCAGGTTTCGCTCAGTCACAACG
ATTCAGCGCGGTACGAAGACCGCTGGTGCCACCTGAAAGTGAATACGCACAGTCCCTGTGTATTCACGCACGGCCTTACT
TCGCTGTATATTCCCGTGCGCCACGGCGAAGGCAAGTTGATTCCCGAAAATGAAGAAACGTTGAAACGACTGGTGGCGGA
AAACCTTGTTGTCTTTCAGTACGCCCACCCCGAGACCATGGAAGTAACTCAGGAATACCCATGGAACCCCAACGGTTCCC
CTCTCGGCATCGCGGGACTGACCGACCCCACCGGGCGTGTGCTGGGCCTGATGCCGCATCCGGAAGCATTCAACCATGTG
ACCAACCATCCCGGCTGGACCCGTGGCGAGAGTGACCCGCTGGGTACGGTTTTGTTCGAAAATGCCGTTGCCTACCTGAA
AAAACAATAG

Upstream 100 bases:

>100_bases
CGGTTCCGAGCAGCAACTGCCCGGATATCTCCACACGCACAAACGTGTGTTGCTACGGAATGGACATTCCTCTGTCAAGC
AAACATTTTCAGGAGCCATG

Downstream 100 bases:

>100_bases
CACTCAGAGCGGAGCATGAATCCATGCTCCGCTTTTCAGTAATTTTTACGGCCTGCCGCAGAGGTGATGATGGTACCTTG
CCTTATTTGCGGAAAAGACG

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTKVNTLVITGYGTNCEVECAHAARIAGADAVEIAHFSDLETGRIRLEDFNFLIFPGGFLDGDDLGAAQAAAQRWRHAQT
KDGTPLLDQLKNFFDRGGLIMGICNGFQLLVKLGLLPALDSMYFERQVSLSHNDSARYEDRWCHLKVNTHSPCVFTHGLT
SLYIPVRHGEGKLIPENEETLKRLVAENLVVFQYAHPETMEVTQEYPWNPNGSPLGIAGLTDPTGRVLGLMPHPEAFNHV
TNHPGWTRGESDPLGTVLFENAVAYLKKQ

Sequences:

>Translated_269_residues
MTKVNTLVITGYGTNCEVECAHAARIAGADAVEIAHFSDLETGRIRLEDFNFLIFPGGFLDGDDLGAAQAAAQRWRHAQT
KDGTPLLDQLKNFFDRGGLIMGICNGFQLLVKLGLLPALDSMYFERQVSLSHNDSARYEDRWCHLKVNTHSPCVFTHGLT
SLYIPVRHGEGKLIPENEETLKRLVAENLVVFQYAHPETMEVTQEYPWNPNGSPLGIAGLTDPTGRVLGLMPHPEAFNHV
TNHPGWTRGESDPLGTVLFENAVAYLKKQ
>Mature_268_residues
TKVNTLVITGYGTNCEVECAHAARIAGADAVEIAHFSDLETGRIRLEDFNFLIFPGGFLDGDDLGAAQAAAQRWRHAQTK
DGTPLLDQLKNFFDRGGLIMGICNGFQLLVKLGLLPALDSMYFERQVSLSHNDSARYEDRWCHLKVNTHSPCVFTHGLTS
LYIPVRHGEGKLIPENEETLKRLVAENLVVFQYAHPETMEVTQEYPWNPNGSPLGIAGLTDPTGRVLGLMPHPEAFNHVT
NHPGWTRGESDPLGTVLFENAVAYLKKQ

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=244, Percent_Identity=33.1967213114754, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI48994899, Length=267, Percent_Identity=38.5767790262172, Blast_Score=127, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17553022, Length=238, Percent_Identity=27.7310924369748, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321498, Length=260, Percent_Identity=32.3076923076923, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24582111, Length=245, Percent_Identity=34.6938775510204, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24582109, Length=245, Percent_Identity=34.6938775510204, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17137292, Length=245, Percent_Identity=34.6938775510204, Blast_Score=119, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 29810; Mature: 29679

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVNTLVITGYGTNCEVECAHAARIAGADAVEIAHFSDLETGRIRLEDFNFLIFPGGFL
CCCEEEEEEEECCCCCEEEEHHHHHHCCCCEEEEEECCCCCCCEEEEEECCEEEEECCCC
DGDDLGAAQAAAQRWRHAQTKDGTPLLDQLKNFFDRGGLIMGICNGFQLLVKLGLLPALD
CCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHH
SMYFERQVSLSHNDSARYEDRWCHLKVNTHSPCVFTHGLTSLYIPVRHGEGKLIPENEET
HHHHHHEECCCCCCCCCCCCCEEEEEECCCCCEEEECCCEEEEEEEECCCCCCCCCCHHH
LKRLVAENLVVFQYAHPETMEVTQEYPWNPNGSPLGIAGLTDPTGRVLGLMPHPEAFNHV
HHHHHHCCEEEEEECCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCEEEECCCCHHHHHC
TNHPGWTRGESDPLGTVLFENAVAYLKKQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKVNTLVITGYGTNCEVECAHAARIAGADAVEIAHFSDLETGRIRLEDFNFLIFPGGFL
CCEEEEEEEECCCCCEEEEHHHHHHCCCCEEEEEECCCCCCCEEEEEECCEEEEECCCC
DGDDLGAAQAAAQRWRHAQTKDGTPLLDQLKNFFDRGGLIMGICNGFQLLVKLGLLPALD
CCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHH
SMYFERQVSLSHNDSARYEDRWCHLKVNTHSPCVFTHGLTSLYIPVRHGEGKLIPENEET
HHHHHHEECCCCCCCCCCCCCEEEEEECCCCCEEEECCCEEEEEEEECCCCCCCCCCHHH
LKRLVAENLVVFQYAHPETMEVTQEYPWNPNGSPLGIAGLTDPTGRVLGLMPHPEAFNHV
HHHHHHCCEEEEEECCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCEEEECCCCHHHHHC
TNHPGWTRGESDPLGTVLFENAVAYLKKQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA