Click here to switch to the map view.

The map label for this gene is engD [H]

Identifier: 78356741

GI number: 78356741

Start: 1752704

End: 1753804

Strand: Reverse

Name: engD [H]

Synonym: Dde_1698

Alternate gene names: 78356741

Gene position: 1753804-1752704 (Counterclockwise)

Preceding gene: 78356742

Following gene: 78356740

Centisome position: 47.02

GC content: 55.77

Gene sequence:

>1101_bases
ATGGCACTTAGCATCGGCATCGTGGGCCTGCCCAACGTAGGCAAATCCACCCTTTTCAACGCGCTGACCAAAGCACAGAA
TGCGGAGTCGGCAAACTACCCCTTCTGCACCATTGAACCCAACAAGGCCACAGTGCCCGTGCCCGATGCCCGCATCGACA
AGCTGACCGCCATGGCCAGACCGCAGAAAACCATCAATGCCACCGTCGACTTTATCGACATAGCCGGACTTGTGCGCGGT
GCAAGCAAAGGTGAAGGGCTGGGCAACCAGTTTCTTGCAAACATCCGCGAATCGGCAGCCATTCTGCAGGTTGTGCGCTG
CTTTGACGACGAGAATATAACCCATGTAGACGGCACGGTTGACCCGCTGCGCGACATTGAAACCATTGAAACCGAGCTGC
TGCTCGCAGATGTGCAATCCGCTGAACGCAAGCTGGACAGAACCCGTCGCCAGTCCAAAGGTGACAAGAGCATGACGGCT
ACCGTCAGCGCCATGGAACGTCTTGTGGACCATCTCAACGCCGGCAACCCCGCATCCACCTTCGCCGAAAAAGACAGCGA
TGCCATCAGCGCACTGTACAAGGAACTCGGCCTGCTGACCGCCAAAAAAATCATCTACTGTGCCAATGTGGATGAAGAAG
GTCTGGCAGAAGACAACCGACACGTTGTCACCGTCAGAGAGTTTGCAGCCTCGCGCTCATGCGACGTGGTCAAAATATGC
GCCAAGGTGGAAGAAGAGCTGCAGGGGCTTGATGAAGCTGAGCAGCTTGATTTTCTGGCCTCCTTCGGCATTCCGGAAAG
CGGGCTGACCAAAGTGATACACACCGGCTATCATACGCTGGGACTCATCAGTTATTTCACCGTGGGCGAAAAAGAAGTGC
GCGCATGGACCATCAAGGAAGGATGGAAAGCCCCTGCCGCAGCCGGCGTCATCCACAGCGACTTCGAGCGCGGCTTCATA
CGGGCTGAAGTCATAGGATACGACGACTATGTAAAGCACGGTTCCGAAGCGGCCTGCCGCACAGCCGGAGTCCTTCGCGT
GGAAGGCAAGGAGTACGTTGTCAGCGACGGGGATATTATTCACTTCCTTTTCAATGTGTAA

Upstream 100 bases:

>100_bases
AAACCGGCCCGTTTTTTTCTTTGTCAATCATCACAAAAACGGCTAAGAAGCCGCCCGAAGGCTTCCGCGCCTTTCCATAT
TTTTTTCCGGAGAATAAACC

Downstream 100 bases:

>100_bases
TACATTCCCCGGAGGTGCTTTGCGGCACCTCCGGGGCTGTCAGGAATTCCGCAGGAATCCGGCCTGATCCGTGTTTCCAG
ATATATTCACGCCCCGACCG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MALSIGIVGLPNVGKSTLFNALTKAQNAESANYPFCTIEPNKATVPVPDARIDKLTAMARPQKTINATVDFIDIAGLVRG
ASKGEGLGNQFLANIRESAAILQVVRCFDDENITHVDGTVDPLRDIETIETELLLADVQSAERKLDRTRRQSKGDKSMTA
TVSAMERLVDHLNAGNPASTFAEKDSDAISALYKELGLLTAKKIIYCANVDEEGLAEDNRHVVTVREFAASRSCDVVKIC
AKVEEELQGLDEAEQLDFLASFGIPESGLTKVIHTGYHTLGLISYFTVGEKEVRAWTIKEGWKAPAAAGVIHSDFERGFI
RAEVIGYDDYVKHGSEAACRTAGVLRVEGKEYVVSDGDIIHFLFNV

Sequences:

>Translated_366_residues
MALSIGIVGLPNVGKSTLFNALTKAQNAESANYPFCTIEPNKATVPVPDARIDKLTAMARPQKTINATVDFIDIAGLVRG
ASKGEGLGNQFLANIRESAAILQVVRCFDDENITHVDGTVDPLRDIETIETELLLADVQSAERKLDRTRRQSKGDKSMTA
TVSAMERLVDHLNAGNPASTFAEKDSDAISALYKELGLLTAKKIIYCANVDEEGLAEDNRHVVTVREFAASRSCDVVKIC
AKVEEELQGLDEAEQLDFLASFGIPESGLTKVIHTGYHTLGLISYFTVGEKEVRAWTIKEGWKAPAAAGVIHSDFERGFI
RAEVIGYDDYVKHGSEAACRTAGVLRVEGKEYVVSDGDIIHFLFNV
>Mature_365_residues
ALSIGIVGLPNVGKSTLFNALTKAQNAESANYPFCTIEPNKATVPVPDARIDKLTAMARPQKTINATVDFIDIAGLVRGA
SKGEGLGNQFLANIRESAAILQVVRCFDDENITHVDGTVDPLRDIETIETELLLADVQSAERKLDRTRRQSKGDKSMTAT
VSAMERLVDHLNAGNPASTFAEKDSDAISALYKELGLLTAKKIIYCANVDEEGLAEDNRHVVTVREFAASRSCDVVKICA
KVEEELQGLDEAEQLDFLASFGIPESGLTKVIHTGYHTLGLISYFTVGEKEVRAWTIKEGWKAPAAAGVIHSDFERGFIR
AEVIGYDDYVKHGSEAACRTAGVLRVEGKEYVVSDGDIIHFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=370, Percent_Identity=42.1621621621622, Blast_Score=291, Evalue=7e-79,
Organism=Homo sapiens, GI58761502, Length=216, Percent_Identity=36.5740740740741, Blast_Score=141, Evalue=8e-34,
Organism=Escherichia coli, GI1787454, Length=369, Percent_Identity=51.7615176151762, Blast_Score=377, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17509631, Length=370, Percent_Identity=42.1621621621622, Blast_Score=278, Evalue=4e-75,
Organism=Saccharomyces cerevisiae, GI6319499, Length=375, Percent_Identity=40.8, Blast_Score=258, Evalue=9e-70,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=35.6200527704486, Blast_Score=211, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6321649, Length=167, Percent_Identity=36.5269461077844, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640873, Length=368, Percent_Identity=41.8478260869565, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24640877, Length=368, Percent_Identity=41.8478260869565, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24640875, Length=368, Percent_Identity=41.8478260869565, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24640879, Length=326, Percent_Identity=39.2638036809816, Blast_Score=227, Evalue=8e-60,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39819; Mature: 39688

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSIGIVGLPNVGKSTLFNALTKAQNAESANYPFCTIEPNKATVPVPDARIDKLTAMAR
CEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHC
PQKTINATVDFIDIAGLVRGASKGEGLGNQFLANIRESAAILQVVRCFDDENITHVDGTV
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
DPLRDIETIETELLLADVQSAERKLDRTRRQSKGDKSMTATVSAMERLVDHLNAGNPAST
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
FAEKDSDAISALYKELGLLTAKKIIYCANVDEEGLAEDNRHVVTVREFAASRSCDVVKIC
HHHCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEEHHHHHCCCCCHHHHHH
AKVEEELQGLDEAEQLDFLASFGIPESGLTKVIHTGYHTLGLISYFTVGEKEVRAWTIKE
HHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHCCCHHHEEEEECC
GWKAPAAAGVIHSDFERGFIRAEVIGYDDYVKHGSEAACRTAGVLRVEGKEYVVSDGDII
CCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHCCCCHHHHHCCEEEECCCEEEECCCCEE
HFLFNV
EEEECC
>Mature Secondary Structure 
ALSIGIVGLPNVGKSTLFNALTKAQNAESANYPFCTIEPNKATVPVPDARIDKLTAMAR
EEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHC
PQKTINATVDFIDIAGLVRGASKGEGLGNQFLANIRESAAILQVVRCFDDENITHVDGTV
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
DPLRDIETIETELLLADVQSAERKLDRTRRQSKGDKSMTATVSAMERLVDHLNAGNPAST
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
FAEKDSDAISALYKELGLLTAKKIIYCANVDEEGLAEDNRHVVTVREFAASRSCDVVKIC
HHHCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEEHHHHHCCCCCHHHHHH
AKVEEELQGLDEAEQLDFLASFGIPESGLTKVIHTGYHTLGLISYFTVGEKEVRAWTIKE
HHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHCCCHHHEEEEECC
GWKAPAAAGVIHSDFERGFIRAEVIGYDDYVKHGSEAACRTAGVLRVEGKEYVVSDGDII
CCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHCCCCHHHHHCCEEEECCCEEEECCCCEE
HFLFNV
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]