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The map label for this gene is pqqL [C]

Identifier: 78356742

GI number: 78356742

Start: 1753926

End: 1756544

Strand: Reverse

Name: pqqL [C]

Synonym: Dde_1699

Alternate gene names: 78356742

Gene position: 1756544-1753926 (Counterclockwise)

Preceding gene: 78356744

Following gene: 78356741

Centisome position: 47.09

GC content: 56.47

Gene sequence:

>2619_bases
ATGAAAAAACAGCGAATTCTAGCCTTTTTTATCGGAGCAGCCTTAATGTTTTTTTCTTTTCAAGCCGCTCATGCCGCCAG
TGTAACCAGACTGGCCAACGGTCTGACTGTACTGATTCAGCAGGATGACCGTTTTCCGCTTGCCTCGCTCAGGCTGTATG
TCCATGCGGGTTCAGCCTATGAAACACCGCAGCAGGCAGGCATAAGCCACCTGCTTGAGCACATGGTGTTCAAAGGGACG
GAAAAACGCCCCGAAGGCGGGGTTGCCGGAGCCATCGAGCAGATAGGCGGCAACATCAATGCCGCAACAAGCTTTGACTA
TACGGTATATCTTACAGATGTACCCTCCGAACACTGGCGTCTGGGCATGGACGTACTCAAGGATATGACTTTCGGTGCAA
AAATCAGCCCTGAAGCGCTGGCTCCGGAAAAAGAGGTTGTTCTTGCCGAACTGGAACGCGGAGAAGACACCCCCGGCAGT
CTTCTCTTCAAACGTCTGACGGCAAAAGTGCTGGCCCGGACCCCGTATGAACGCCCCATCATCGGGTACCGCGAAACAGT
GAGCGCGATAACCAGCAAAGACATTCACGACTATATCGACCGCCTGTACCAGCCGCAGTCCATGCTGCTGGTGGTATGCG
GAGCCGTGAACGAACAGGAGGTGCTGGCAGAAGCTGAAAAGCTTTTCGGAAATCTTGCAAACACCCGGACTTGCGTGCCC
CCGCAGCCGGTCACACCACCCGTTTCGCCCGCCGCCCCCGCACTGACTGCGGAGCCGGGCAAGTGGAACAAGGTCTACGC
GGGATTCGCCCTGCCTATTCCCAACTTTCATGATGCCCGGATACCTGCCGTCGAAGTACTTGCCCAGATGCTGGGCGGAG
ATAAAACCTCTCTGCTTTACAGAGAGTTCAAGTACGACAAGCAGCTTGTGGACGATATCTCAGTCTCTGCCTATTCCTTT
GAGCGCACAGGACTTCTGCTGATTACGGCCATACTTGATCCGCAGAAAACAGAGAAATTCACCCGCGAGCTTTCGGCGGC
ACTGGCGCGGCTGAGTGCGGACAGTTTCACAGACAACGCTCTGGCGCGGGCAAAGCTCAATCTGGAAGACGAACTGTTCC
GGTCCAAGGAAACGCTGTCCGGTCTGGCTTCCAAGCTGGGACATTTTTATTTTTTTGAAAACGGCGAACAAAGTGAACTG
AACTATCTGCAAAGCCTCCGTCAGGTGGAAAAAACATCAGTTCAGGACATTCTGGACACTTTTTTCACTCCCGAAAGGCT
GAACGGAGTGCTGCTTACTCCGCAGAATGCCGGACTGAACAGCGATGACCTGACAGAGCTGTTCCGCGACGGCTGGCCCG
CAAAGGGCAGCGGGCATGCCGCCCCCGCGGAAAAAGGTGACAACGGGCAGCAGCAGGAAGTGATTGAACTGGGCGACGGG
CGCACTGTGGTGCTCATTCCCGACGAGACACTTCCTTATACGGCGGTCGATCTGGTGTTCCGCGGCGGTGATGCCCTGCT
GGATGAAGACAGGCAGGGTCTTGCAGCCCTTGCAGCCAGAGTGCTGACCAAAGGCACCCAGCAGATGGACAATGCCGCTC
TGGAGGCTTTCAAGGCAGACAGAGCAGCCAGTCTGGCCGCTTCTGCAGGCAGATCGTCTTTCACCATCAGCGCGCGCTAC
CCGGAAAGATTCAGTGCCGACATCACCGGTCTGTTCCGCAACGTTGTCACCGCTCCGGCACTGGCTGCAGAAGAAACCGC
GCGTGAAAAAGACAACCAGATTGCATCCATAAAGGCCCGTGAAGATCAGCCGCTCGGGCTTGCGTTCCGCAGATTGTTTC
CGTTTCTTTTCCACAACAGTGCTTACGGATACCTGCATCTGGGTGAAGAGCAGCGTCTTGCCGCCTACACCGCGGAAGAT
GTGGCCGGATTCTGGAAAGTGCAGCGGACACAACCATGGGTGCTTGCGGTATGCGGACAGTTCGACCGCGAAGAGATTCT
CGGGCTGGCACGCAGCCTGCCCGCCCCCTCCGGGCCTGTCGCCGTGCCTGCGGTGCCGCTGTGGTCTGCTGAAACACAGC
TGGATATCTCGCTGGAGGACAGAAATCAGGCGCATATGCTGATGATATTCAAAACCGTACCCATAACGCATGAAGACACC
CCGGCGCTGGAGCTGCTGCAGACAGTTCTTGCCGGACAATCCGGCCTGCTTTTTACAGATCTGCGCGACAAACAGGGGCT
TGGCTACACTGTGACGGCGTTCCCGTGGCAGTCGGAACATGCCGGTCTGCTGGCTTTTTATATTGGCACCGACCCTGAAA
AACTTGCACAGGCCGACGCCGGTTTTAAAAAAGTAATCCGCGATCTGCAGGAGGCCCCCCTGCCTGAAGAAGCCATCCGC
CGCGGTAAAAACATGCTGCGGGGCGACTACTACCGGGGCAGGCAGAGTCTTGGCAGCCGCAGCAACGAAGCCGCCCGCCT
TGCCGGCTCGGGGCTGCCTCTTGATTTTGAAAAAGGACTTATCGAAAAAGCGGAAAAAGTGGATGCCACCGCCCTGCAGG
AGGTGGCCCGCAGATATCTCATTCCGCAGGATGCGTATATCATCAGGGTACTGCCCTGA

Upstream 100 bases:

>100_bases
CGACTTTCTTGCCTTGTCCCGCAGAAGGATTACCTGTAAAACTCTGCACCGTACGATGAGGAAACACCTTGCAGCGCCTT
TGCGGACCAAGGAGACACAT

Downstream 100 bases:

>100_bases
CATTCCGGGCCGGTTTGGCGCAAACCGGCCCGTTTTTTTCTTTGTCAATCATCACAAAAACGGCTAAGAAGCCGCCCGAA
GGCTTCCGCGCCTTTCCATA

Product: M16 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 872; Mature: 872

Protein sequence:

>872_residues
MKKQRILAFFIGAALMFFSFQAAHAASVTRLANGLTVLIQQDDRFPLASLRLYVHAGSAYETPQQAGISHLLEHMVFKGT
EKRPEGGVAGAIEQIGGNINAATSFDYTVYLTDVPSEHWRLGMDVLKDMTFGAKISPEALAPEKEVVLAELERGEDTPGS
LLFKRLTAKVLARTPYERPIIGYRETVSAITSKDIHDYIDRLYQPQSMLLVVCGAVNEQEVLAEAEKLFGNLANTRTCVP
PQPVTPPVSPAAPALTAEPGKWNKVYAGFALPIPNFHDARIPAVEVLAQMLGGDKTSLLYREFKYDKQLVDDISVSAYSF
ERTGLLLITAILDPQKTEKFTRELSAALARLSADSFTDNALARAKLNLEDELFRSKETLSGLASKLGHFYFFENGEQSEL
NYLQSLRQVEKTSVQDILDTFFTPERLNGVLLTPQNAGLNSDDLTELFRDGWPAKGSGHAAPAEKGDNGQQQEVIELGDG
RTVVLIPDETLPYTAVDLVFRGGDALLDEDRQGLAALAARVLTKGTQQMDNAALEAFKADRAASLAASAGRSSFTISARY
PERFSADITGLFRNVVTAPALAAEETAREKDNQIASIKAREDQPLGLAFRRLFPFLFHNSAYGYLHLGEEQRLAAYTAED
VAGFWKVQRTQPWVLAVCGQFDREEILGLARSLPAPSGPVAVPAVPLWSAETQLDISLEDRNQAHMLMIFKTVPITHEDT
PALELLQTVLAGQSGLLFTDLRDKQGLGYTVTAFPWQSEHAGLLAFYIGTDPEKLAQADAGFKKVIRDLQEAPLPEEAIR
RGKNMLRGDYYRGRQSLGSRSNEAARLAGSGLPLDFEKGLIEKAEKVDATALQEVARRYLIPQDAYIIRVLP

Sequences:

>Translated_872_residues
MKKQRILAFFIGAALMFFSFQAAHAASVTRLANGLTVLIQQDDRFPLASLRLYVHAGSAYETPQQAGISHLLEHMVFKGT
EKRPEGGVAGAIEQIGGNINAATSFDYTVYLTDVPSEHWRLGMDVLKDMTFGAKISPEALAPEKEVVLAELERGEDTPGS
LLFKRLTAKVLARTPYERPIIGYRETVSAITSKDIHDYIDRLYQPQSMLLVVCGAVNEQEVLAEAEKLFGNLANTRTCVP
PQPVTPPVSPAAPALTAEPGKWNKVYAGFALPIPNFHDARIPAVEVLAQMLGGDKTSLLYREFKYDKQLVDDISVSAYSF
ERTGLLLITAILDPQKTEKFTRELSAALARLSADSFTDNALARAKLNLEDELFRSKETLSGLASKLGHFYFFENGEQSEL
NYLQSLRQVEKTSVQDILDTFFTPERLNGVLLTPQNAGLNSDDLTELFRDGWPAKGSGHAAPAEKGDNGQQQEVIELGDG
RTVVLIPDETLPYTAVDLVFRGGDALLDEDRQGLAALAARVLTKGTQQMDNAALEAFKADRAASLAASAGRSSFTISARY
PERFSADITGLFRNVVTAPALAAEETAREKDNQIASIKAREDQPLGLAFRRLFPFLFHNSAYGYLHLGEEQRLAAYTAED
VAGFWKVQRTQPWVLAVCGQFDREEILGLARSLPAPSGPVAVPAVPLWSAETQLDISLEDRNQAHMLMIFKTVPITHEDT
PALELLQTVLAGQSGLLFTDLRDKQGLGYTVTAFPWQSEHAGLLAFYIGTDPEKLAQADAGFKKVIRDLQEAPLPEEAIR
RGKNMLRGDYYRGRQSLGSRSNEAARLAGSGLPLDFEKGLIEKAEKVDATALQEVARRYLIPQDAYIIRVLP
>Mature_872_residues
MKKQRILAFFIGAALMFFSFQAAHAASVTRLANGLTVLIQQDDRFPLASLRLYVHAGSAYETPQQAGISHLLEHMVFKGT
EKRPEGGVAGAIEQIGGNINAATSFDYTVYLTDVPSEHWRLGMDVLKDMTFGAKISPEALAPEKEVVLAELERGEDTPGS
LLFKRLTAKVLARTPYERPIIGYRETVSAITSKDIHDYIDRLYQPQSMLLVVCGAVNEQEVLAEAEKLFGNLANTRTCVP
PQPVTPPVSPAAPALTAEPGKWNKVYAGFALPIPNFHDARIPAVEVLAQMLGGDKTSLLYREFKYDKQLVDDISVSAYSF
ERTGLLLITAILDPQKTEKFTRELSAALARLSADSFTDNALARAKLNLEDELFRSKETLSGLASKLGHFYFFENGEQSEL
NYLQSLRQVEKTSVQDILDTFFTPERLNGVLLTPQNAGLNSDDLTELFRDGWPAKGSGHAAPAEKGDNGQQQEVIELGDG
RTVVLIPDETLPYTAVDLVFRGGDALLDEDRQGLAALAARVLTKGTQQMDNAALEAFKADRAASLAASAGRSSFTISARY
PERFSADITGLFRNVVTAPALAAEETAREKDNQIASIKAREDQPLGLAFRRLFPFLFHNSAYGYLHLGEEQRLAAYTAED
VAGFWKVQRTQPWVLAVCGQFDREEILGLARSLPAPSGPVAVPAVPLWSAETQLDISLEDRNQAHMLMIFKTVPITHEDT
PALELLQTVLAGQSGLLFTDLRDKQGLGYTVTAFPWQSEHAGLLAFYIGTDPEKLAQADAGFKKVIRDLQEAPLPEEAIR
RGKNMLRGDYYRGRQSLGSRSNEAARLAGSGLPLDFEKGLIEKAEKVDATALQEVARRYLIPQDAYIIRVLP

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=217, Percent_Identity=31.7972350230415, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI46593007, Length=404, Percent_Identity=22.029702970297, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI155969707, Length=224, Percent_Identity=27.6785714285714, Blast_Score=70, Evalue=7e-12,
Organism=Escherichia coli, GI1787770, Length=215, Percent_Identity=28.3720930232558, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71999683, Length=218, Percent_Identity=30.7339449541284, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17553678, Length=371, Percent_Identity=25.0673854447439, Blast_Score=98, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323192, Length=212, Percent_Identity=31.1320754716981, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6321813, Length=231, Percent_Identity=24.6753246753247, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21357875, Length=222, Percent_Identity=31.0810810810811, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24646943, Length=222, Percent_Identity=31.0810810810811, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221513245, Length=227, Percent_Identity=27.7533039647577, Blast_Score=68, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 95831; Mature: 95831

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQRILAFFIGAALMFFSFQAAHAASVTRLANGLTVLIQQDDRFPLASLRLYVHAGSAY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHEEEEEECCCCC
ETPQQAGISHLLEHMVFKGTEKRPEGGVAGAIEQIGGNINAATSFDYTVYLTDVPSEHWR
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEECCEEEEEEECCCCHHHH
LGMDVLKDMTFGAKISPEALAPEKEVVLAELERGEDTPGSLLFKRLTAKVLARTPYERPI
HHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC
IGYRETVSAITSKDIHDYIDRLYQPQSMLLVVCGAVNEQEVLAEAEKLFGNLANTRTCVP
CCHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCC
PQPVTPPVSPAAPALTAEPGKWNKVYAGFALPIPNFHDARIPAVEVLAQMLGGDKTSLLY
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHH
REFKYDKQLVDDISVSAYSFERTGLLLITAILDPQKTEKFTRELSAALARLSADSFTDNA
HHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCH
LARAKLNLEDELFRSKETLSGLASKLGHFYFFENGEQSELNYLQSLRQVEKTSVQDILDT
HHHEECCCHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
FFTPERLNGVLLTPQNAGLNSDDLTELFRDGWPAKGSGHAAPAEKGDNGQQQEVIELGDG
HCCHHHCCEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHEECCC
RTVVLIPDETLPYTAVDLVFRGGDALLDEDRQGLAALAARVLTKGTQQMDNAALEAFKAD
CEEEEECCCCCCCCEEHEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAASLAASAGRSSFTISARYPERFSADITGLFRNVVTAPALAAEETAREKDNQIASIKAR
HHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECC
EDQPLGLAFRRLFPFLFHNSAYGYLHLGEEQRLAAYTAEDVAGFWKVQRTQPWVLAVCGQ
CCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHEECCCCCEEEEECCC
FDREEILGLARSLPAPSGPVAVPAVPLWSAETQLDISLEDRNQAHMLMIFKTVPITHEDT
CCHHHHHHHHHHCCCCCCCEECCCEECCCCCCEEEEEECCCCCCEEEEEEEECCCCCCCC
PALELLQTVLAGQSGLLFTDLRDKQGLGYTVTAFPWQSEHAGLLAFYIGTDPEKLAQADA
HHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHCC
GFKKVIRDLQEAPLPEEAIRRGKNMLRGDYYRGRQSLGSRSNEAARLAGSGLPLDFEKGL
CHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHH
IEKAEKVDATALQEVARRYLIPQDAYIIRVLP
HHHHHHCCHHHHHHHHHHHCCCCCCEEEEECC
>Mature Secondary Structure
MKKQRILAFFIGAALMFFSFQAAHAASVTRLANGLTVLIQQDDRFPLASLRLYVHAGSAY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHEEEEEECCCCC
ETPQQAGISHLLEHMVFKGTEKRPEGGVAGAIEQIGGNINAATSFDYTVYLTDVPSEHWR
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEECCEEEEEEECCCCHHHH
LGMDVLKDMTFGAKISPEALAPEKEVVLAELERGEDTPGSLLFKRLTAKVLARTPYERPI
HHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC
IGYRETVSAITSKDIHDYIDRLYQPQSMLLVVCGAVNEQEVLAEAEKLFGNLANTRTCVP
CCHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCC
PQPVTPPVSPAAPALTAEPGKWNKVYAGFALPIPNFHDARIPAVEVLAQMLGGDKTSLLY
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHH
REFKYDKQLVDDISVSAYSFERTGLLLITAILDPQKTEKFTRELSAALARLSADSFTDNA
HHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCH
LARAKLNLEDELFRSKETLSGLASKLGHFYFFENGEQSELNYLQSLRQVEKTSVQDILDT
HHHEECCCHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
FFTPERLNGVLLTPQNAGLNSDDLTELFRDGWPAKGSGHAAPAEKGDNGQQQEVIELGDG
HCCHHHCCEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHEECCC
RTVVLIPDETLPYTAVDLVFRGGDALLDEDRQGLAALAARVLTKGTQQMDNAALEAFKAD
CEEEEECCCCCCCCEEHEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAASLAASAGRSSFTISARYPERFSADITGLFRNVVTAPALAAEETAREKDNQIASIKAR
HHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECC
EDQPLGLAFRRLFPFLFHNSAYGYLHLGEEQRLAAYTAEDVAGFWKVQRTQPWVLAVCGQ
CCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHEECCCCCEEEEECCC
FDREEILGLARSLPAPSGPVAVPAVPLWSAETQLDISLEDRNQAHMLMIFKTVPITHEDT
CCHHHHHHHHHHCCCCCCCEECCCEECCCCCCEEEEEECCCCCCEEEEEEEECCCCCCCC
PALELLQTVLAGQSGLLFTDLRDKQGLGYTVTAFPWQSEHAGLLAFYIGTDPEKLAQADA
HHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHCC
GFKKVIRDLQEAPLPEEAIRRGKNMLRGDYYRGRQSLGSRSNEAARLAGSGLPLDFEKGL
CHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHH
IEKAEKVDATALQEVARRYLIPQDAYIIRVLP
HHHHHHCCHHHHHHHHHHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]