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The map label for this gene is clpB [H]

Identifier: 78356704

GI number: 78356704

Start: 1712857

End: 1715448

Strand: Direct

Name: clpB [H]

Synonym: Dde_1661

Alternate gene names: 78356704

Gene position: 1712857-1715448 (Clockwise)

Preceding gene: 78356703

Following gene: 78356705

Centisome position: 45.92

GC content: 56.94

Gene sequence:

>2592_bases
ATGGATATAAGCAAGTTTACTGAAAAATCGCAGCAGGCTCTGGGCGAAGCGCAGAATGTGGCTGTGCGGGCAGGCCATCA
GGAGGTTGATGTCGAGCATCTTGCGCTCGCGCTGGTGGTGCAGGAGCATGGGATTGTTCCCCGTCTGCTGGACAAGGCGG
GAGTGCGCCCCCAAGCTTTTGCCGCGGCTGTCGAGGCGGAACTGGGCAGAAAGCCTGCTGTAAGCGGTCCGGGTTCGGCG
CAGGGGCAGATTTTTGTCACGCAGCGGCTTAACAGGCTGCTTGTAAAAGCGCAGGATTCCGCCCGTCGCCTGCAGGACGA
GTACGTCAGTGTGGAACATATTTTCTGCGCCATGGCTGAAGAACCAGCCTCAAGCCCGGTGGGCAGAGTGTTTGCTCAGT
TCGGGCTGACACAGGAAAAGCTGCTGGGCGTACTGACTCAGGTCCGCGGTGCACAGCGCGTAACGTCATCCAACCCTGAA
GATACCTATGAAGCCCTCAGCCGTTACGGTCGAGATCTTGTGGAGGAGGCGCGCAAGGGCAAGCTTGATCCGGTGATTGG
CCGTGATGCCGAGATAAGGCGCACGGTACGCATTCTTTCGCGGCGCACAAAAAACAACCCTGTGCTCATCGGCGAGGCCG
GAGTGGGTAAAACCGCCATTGTTGAGGGGCTGGCACACCGCATACTCAACGGTGACGTACCCGAAAGTCTGCGCGACAAG
AGCCTTTTTGCACTGGATATGGGGGCGCTTATTGCAGGCGCCAAATATCGCGGAGAGTTTGAGGAACGCCTGAAAGCGGT
GCTGAAAGAGGTTGAGCAGGCCGAGGGCCGCATAATCATGTTCATAGACGAACTGCATACCATTGTGGGGGCCGGCAAGA
CGGACGGCGCCATGGATGCGGGCAACCTGCTCAAACCCATGCTTGCACGCGGCGAACTGCATTGCATCGGGGCCACAACG
CTGGATGAATACCGCAAGTATATAGAAAAGGATCCGGCACTGGAACGCCGTTTTCAGCCTCTGGTGGTGGATGAGCCTAC
GGTGGAAGATACCATTTCGATTCTCCGCGGTCTCAAGGAGCGGTTCGAGGTGCACCACGGGGTACGCATCAGTGACTCCG
CACTGGTGGAGGCTGTCACGCTTTCCAACAGGTATATTGCCGACAGGCAGCTTCCGGACAAAGCCATTGACCTTATCGAC
GAGGCCGCTGCGCTTATCAGGACCGAAATTGATTCGCTGCCCGCTGAACTGGACGAAGCCAACCGTAAGATCATGCAGCT
GGAAATTGAACGTGAAGCTTTGCGGCGTGAGACGGATGCGGCGTCTCGTGAACGGCTGCAAAAGCTGGAGAATGAGCTGG
CTGAACTGCGCGAGGTACAGGCGGGACTGAATACCCAGTGGGAACGCGAAAAGGGTTCTATAGACAGCGTGCGCGCGCTT
AAGGAAGACATTGAGCGCACGCGGCGTCAGATAGAGGAGGCGGAACGCAATTACGATCTTAACCGTGCTGCGGAGCTGAA
GTATTCAGTGCTGCACGATCTGGAAAAACGTCTTGCGGCAACCGAGGGCGGCGGCGAAAACGGCCCGCGGCTGCTGAAGG
AGGAAGTAGGTCCGGATGATGTGGCAGAGATAGTAGCCCGCTGGACAGGAATTCCCGTGACGCGTCTGCTTGAATCGGAA
AGGGAAAAGCTGCTCCGTCTGCCCGATGTGCTGCATCAGCGGGTTGTGGGGCAGGATGTGGCGGTAGATGCCGTGGCAGA
AGCGGTGCTGCGCTCGCGCGCCGGGCTGTCCGACCCTGCGAGACCCATCGGTTCTTTCATTTTCCTCGGACCCACCGGAG
TGGGAAAAACCGAGCTGTGCAAGACCCTTGCGCAGGCGCTTTTTGATACTGAAGATAATATTGTCCGGCTGGACATGAGT
GAATACATGGAAAAACATACCGTGGCACGCCTTATCGGAGCGCCTCCCGGGTATGTGGGTTATGACGATGGCGGGCAGCT
GACCGAAGCGGTGCGTCGCAAACCGTATAGTGTTGTGCTTTTTGATGAAATTGAAAAAGCGCATCCTGATGTGTTTAATG
TGCTGCTGCAACTGCTGGACGACGGCAGACTGACGGACAGTCACGGCCGGACAGTGGATTTCAAAAACACTATCATCATC
ATGACCTCCAACATAGGTGCCCCGCTCATGCTGGACGGCATTTCGCCGCAGGGCGAATTTACCGAAGGAGTGGAAGACAG
GGTGCTTGAAGAACTCCGGCGGCATTTCAGACCGGAATTTCTCAACAGGGTTGATGAGATAGTGCTCTTCAAGCCTCTTA
TGCTTGAACAGATCATGCATATTGTCGATCTGCTCATGCAGCGCCTGCTGGGGCGCCTTGCCGAACGCAAAATCCGCGTG
AGCCTGACGGACAAGGCGAAACGGTTCGTTGCCGAGTCCGCATACGATCCCGTATACGGAGCGCGTCCGCTGAAGAGGTA
CCTGCAGCAGCGCCTTGAAACTCCGCTGGCCCGCAGGATAATTGCCGGAGAACTGCGTGACGGACAGCAGGTGACCGTGG
ATACCGACGGTCATACGCTGTTTTTTGAATAA

Upstream 100 bases:

>100_bases
GTCGATTTGCTGGAACGTATCGATCAGCTGGAGCGTAAAGTAAGTTCATTGGAAAAACTGCTTTAGTTCTGCATTTTCTG
ACGATACGGAGGAGAAAAAA

Downstream 100 bases:

>100_bases
CAGTATATGCGACAAAAAGGACGGCCGCCGTACAGGGCGGCCGTTCTGCGTTGCGTGCGGCTGTGTTGTCTGCTACATGC
TGACCCATTCCATATAAAGT

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 863; Mature: 863

Protein sequence:

>863_residues
MDISKFTEKSQQALGEAQNVAVRAGHQEVDVEHLALALVVQEHGIVPRLLDKAGVRPQAFAAAVEAELGRKPAVSGPGSA
QGQIFVTQRLNRLLVKAQDSARRLQDEYVSVEHIFCAMAEEPASSPVGRVFAQFGLTQEKLLGVLTQVRGAQRVTSSNPE
DTYEALSRYGRDLVEEARKGKLDPVIGRDAEIRRTVRILSRRTKNNPVLIGEAGVGKTAIVEGLAHRILNGDVPESLRDK
SLFALDMGALIAGAKYRGEFEERLKAVLKEVEQAEGRIIMFIDELHTIVGAGKTDGAMDAGNLLKPMLARGELHCIGATT
LDEYRKYIEKDPALERRFQPLVVDEPTVEDTISILRGLKERFEVHHGVRISDSALVEAVTLSNRYIADRQLPDKAIDLID
EAAALIRTEIDSLPAELDEANRKIMQLEIEREALRRETDAASRERLQKLENELAELREVQAGLNTQWEREKGSIDSVRAL
KEDIERTRRQIEEAERNYDLNRAAELKYSVLHDLEKRLAATEGGGENGPRLLKEEVGPDDVAEIVARWTGIPVTRLLESE
REKLLRLPDVLHQRVVGQDVAVDAVAEAVLRSRAGLSDPARPIGSFIFLGPTGVGKTELCKTLAQALFDTEDNIVRLDMS
EYMEKHTVARLIGAPPGYVGYDDGGQLTEAVRRKPYSVVLFDEIEKAHPDVFNVLLQLLDDGRLTDSHGRTVDFKNTIII
MTSNIGAPLMLDGISPQGEFTEGVEDRVLEELRRHFRPEFLNRVDEIVLFKPLMLEQIMHIVDLLMQRLLGRLAERKIRV
SLTDKAKRFVAESAYDPVYGARPLKRYLQQRLETPLARRIIAGELRDGQQVTVDTDGHTLFFE

Sequences:

>Translated_863_residues
MDISKFTEKSQQALGEAQNVAVRAGHQEVDVEHLALALVVQEHGIVPRLLDKAGVRPQAFAAAVEAELGRKPAVSGPGSA
QGQIFVTQRLNRLLVKAQDSARRLQDEYVSVEHIFCAMAEEPASSPVGRVFAQFGLTQEKLLGVLTQVRGAQRVTSSNPE
DTYEALSRYGRDLVEEARKGKLDPVIGRDAEIRRTVRILSRRTKNNPVLIGEAGVGKTAIVEGLAHRILNGDVPESLRDK
SLFALDMGALIAGAKYRGEFEERLKAVLKEVEQAEGRIIMFIDELHTIVGAGKTDGAMDAGNLLKPMLARGELHCIGATT
LDEYRKYIEKDPALERRFQPLVVDEPTVEDTISILRGLKERFEVHHGVRISDSALVEAVTLSNRYIADRQLPDKAIDLID
EAAALIRTEIDSLPAELDEANRKIMQLEIEREALRRETDAASRERLQKLENELAELREVQAGLNTQWEREKGSIDSVRAL
KEDIERTRRQIEEAERNYDLNRAAELKYSVLHDLEKRLAATEGGGENGPRLLKEEVGPDDVAEIVARWTGIPVTRLLESE
REKLLRLPDVLHQRVVGQDVAVDAVAEAVLRSRAGLSDPARPIGSFIFLGPTGVGKTELCKTLAQALFDTEDNIVRLDMS
EYMEKHTVARLIGAPPGYVGYDDGGQLTEAVRRKPYSVVLFDEIEKAHPDVFNVLLQLLDDGRLTDSHGRTVDFKNTIII
MTSNIGAPLMLDGISPQGEFTEGVEDRVLEELRRHFRPEFLNRVDEIVLFKPLMLEQIMHIVDLLMQRLLGRLAERKIRV
SLTDKAKRFVAESAYDPVYGARPLKRYLQQRLETPLARRIIAGELRDGQQVTVDTDGHTLFFE
>Mature_863_residues
MDISKFTEKSQQALGEAQNVAVRAGHQEVDVEHLALALVVQEHGIVPRLLDKAGVRPQAFAAAVEAELGRKPAVSGPGSA
QGQIFVTQRLNRLLVKAQDSARRLQDEYVSVEHIFCAMAEEPASSPVGRVFAQFGLTQEKLLGVLTQVRGAQRVTSSNPE
DTYEALSRYGRDLVEEARKGKLDPVIGRDAEIRRTVRILSRRTKNNPVLIGEAGVGKTAIVEGLAHRILNGDVPESLRDK
SLFALDMGALIAGAKYRGEFEERLKAVLKEVEQAEGRIIMFIDELHTIVGAGKTDGAMDAGNLLKPMLARGELHCIGATT
LDEYRKYIEKDPALERRFQPLVVDEPTVEDTISILRGLKERFEVHHGVRISDSALVEAVTLSNRYIADRQLPDKAIDLID
EAAALIRTEIDSLPAELDEANRKIMQLEIEREALRRETDAASRERLQKLENELAELREVQAGLNTQWEREKGSIDSVRAL
KEDIERTRRQIEEAERNYDLNRAAELKYSVLHDLEKRLAATEGGGENGPRLLKEEVGPDDVAEIVARWTGIPVTRLLESE
REKLLRLPDVLHQRVVGQDVAVDAVAEAVLRSRAGLSDPARPIGSFIFLGPTGVGKTELCKTLAQALFDTEDNIVRLDMS
EYMEKHTVARLIGAPPGYVGYDDGGQLTEAVRRKPYSVVLFDEIEKAHPDVFNVLLQLLDDGRLTDSHGRTVDFKNTIII
MTSNIGAPLMLDGISPQGEFTEGVEDRVLEELRRHFRPEFLNRVDEIVLFKPLMLEQIMHIVDLLMQRLLGRLAERKIRV
SLTDKAKRFVAESAYDPVYGARPLKRYLQQRLETPLARRIIAGELRDGQQVTVDTDGHTLFFE

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=297, Percent_Identity=37.7104377104377, Blast_Score=200, Evalue=6e-51,
Organism=Escherichia coli, GI1788943, Length=858, Percent_Identity=54.7785547785548, Blast_Score=927, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=327, Percent_Identity=45.2599388379205, Blast_Score=288, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6320464, Length=692, Percent_Identity=54.1907514450867, Blast_Score=769, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=871, Percent_Identity=42.1354764638347, Blast_Score=648, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96408; Mature: 96408

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISKFTEKSQQALGEAQNVAVRAGHQEVDVEHLALALVVQEHGIVPRLLDKAGVRPQAF
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHH
AAAVEAELGRKPAVSGPGSAQGQIFVTQRLNRLLVKAQDSARRLQDEYVSVEHIFCAMAE
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EPASSPVGRVFAQFGLTQEKLLGVLTQVRGAQRVTSSNPEDTYEALSRYGRDLVEEARKG
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
KLDPVIGRDAEIRRTVRILSRRTKNNPVLIGEAGVGKTAIVEGLAHRILNGDVPESLRDK
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCC
SLFALDMGALIAGAKYRGEFEERLKAVLKEVEQAEGRIIMFIDELHTIVGAGKTDGAMDA
CHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCCH
GNLLKPMLARGELHCIGATTLDEYRKYIEKDPALERRFQPLVVDEPTVEDTISILRGLKE
HHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHH
RFEVHHGVRISDSALVEAVTLSNRYIADRQLPDKAIDLIDEAAALIRTEIDSLPAELDEA
HHHHHCCCCCCCHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRKIMQLEIEREALRRETDAASRERLQKLENELAELREVQAGLNTQWEREKGSIDSVRAL
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHH
KEDIERTRRQIEEAERNYDLNRAAELKYSVLHDLEKRLAATEGGGENGPRLLKEEVGPDD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHH
VAEIVARWTGIPVTRLLESEREKLLRLPDVLHQRVVGQDVAVDAVAEAVLRSRAGLSDPA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
RPIGSFIFLGPTGVGKTELCKTLAQALFDTEDNIVRLDMSEYMEKHTVARLIGAPPGYVG
HHHCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCC
YDDGGQLTEAVRRKPYSVVLFDEIEKAHPDVFNVLLQLLDDGRLTDSHGRTVDFKNTIII
CCCCHHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEE
MTSNIGAPLMLDGISPQGEFTEGVEDRVLEELRRHFRPEFLNRVDEIVLFKPLMLEQIMH
EECCCCCCEEECCCCCCCCHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IVDLLMQRLLGRLAERKIRVSLTDKAKRFVAESAYDPVYGARPLKRYLQQRLETPLARRI
HHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHH
IAGELRDGQQVTVDTDGHTLFFE
HHHHCCCCCEEEEECCCCEEEEC
>Mature Secondary Structure
MDISKFTEKSQQALGEAQNVAVRAGHQEVDVEHLALALVVQEHGIVPRLLDKAGVRPQAF
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHH
AAAVEAELGRKPAVSGPGSAQGQIFVTQRLNRLLVKAQDSARRLQDEYVSVEHIFCAMAE
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EPASSPVGRVFAQFGLTQEKLLGVLTQVRGAQRVTSSNPEDTYEALSRYGRDLVEEARKG
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
KLDPVIGRDAEIRRTVRILSRRTKNNPVLIGEAGVGKTAIVEGLAHRILNGDVPESLRDK
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCC
SLFALDMGALIAGAKYRGEFEERLKAVLKEVEQAEGRIIMFIDELHTIVGAGKTDGAMDA
CHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCCH
GNLLKPMLARGELHCIGATTLDEYRKYIEKDPALERRFQPLVVDEPTVEDTISILRGLKE
HHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHH
RFEVHHGVRISDSALVEAVTLSNRYIADRQLPDKAIDLIDEAAALIRTEIDSLPAELDEA
HHHHHCCCCCCCHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRKIMQLEIEREALRRETDAASRERLQKLENELAELREVQAGLNTQWEREKGSIDSVRAL
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHH
KEDIERTRRQIEEAERNYDLNRAAELKYSVLHDLEKRLAATEGGGENGPRLLKEEVGPDD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHH
VAEIVARWTGIPVTRLLESEREKLLRLPDVLHQRVVGQDVAVDAVAEAVLRSRAGLSDPA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
RPIGSFIFLGPTGVGKTELCKTLAQALFDTEDNIVRLDMSEYMEKHTVARLIGAPPGYVG
HHHCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCC
YDDGGQLTEAVRRKPYSVVLFDEIEKAHPDVFNVLLQLLDDGRLTDSHGRTVDFKNTIII
CCCCHHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEE
MTSNIGAPLMLDGISPQGEFTEGVEDRVLEELRRHFRPEFLNRVDEIVLFKPLMLEQIMH
EECCCCCCEEECCCCCCCCHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IVDLLMQRLLGRLAERKIRVSLTDKAKRFVAESAYDPVYGARPLKRYLQQRLETPLARRI
HHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHH
IAGELRDGQQVTVDTDGHTLFFE
HHHHCCCCCEEEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA