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The map label for this gene is stc [H]

Identifier: 78356595

GI number: 78356595

Start: 1570769

End: 1572346

Strand: Direct

Name: stc [H]

Synonym: Dde_1552

Alternate gene names: 78356595

Gene position: 1570769-1572346 (Clockwise)

Preceding gene: 78356594

Following gene: 78356596

Centisome position: 42.11

GC content: 57.03

Gene sequence:

>1578_bases
ATGAAGCTCAAGCTTGAACTTATTTTCAAAGACCGCGTGGGTGTTGTTTCCGACCTTTCTTCATTGCTGGCCGGCCATGC
ATTTTCCATTTCTTCCATGGAGGTGGAACGTAAGACTGACAAAGCCTTTGTATATATCGAGGCGGAAAAGTGGGACGAGG
CCGTGGAGCGGGCGGCGCTTTTTAAAGTGCTCAGCAGAATTCCCGACCTGCTGGAATTCCGCATTGTGGAAACATTGCCC
GGTGAAGAACGTGAAAAGCGTTTCAAGGTCGTGCTGGACAATATCAGTGACGGAGTGCTGTCCATCGATGCTCGGGGCAG
GGTGACAGCCATCAATGCCGTTCTGCGTCAGGTTTACGGCTGCGGCCCAGATGCGGCGGGCAAGCCGCTTGCTTCTCTGG
GACTGCCGGATAACGGGCTTCTGGAGTGCCTTGAGGGTAAGGAGCTGCTTAATGCCAAGCGTGAGATAGCCACCTCTGAC
GGGCGGGTACAGTACTTTGTGACCCGCCGTCCCATACGCGACTCCAATGACCGCATTGTCGGGGCTGTGGAACTGGCCCG
CGATATGCGTGAAATCCGGCAGCTGGCCCGTTCCATAACCGATCCGGAACAGATCGGATTTGGCGATATTGTCGGCAGGG
ATGCTGCCATCGCTTTTGCCATCAGCTTTGCAGAGCAGGTTGCGGCAACAGACTCCATCATTTCCATCCGCGGAGAAAGC
GGAACAGGCAAAGAGCTTTTTGCCCGTGCCATTCATACAGCCAGCAGGCGCAGCGGACCTTTTGTTCCTGTAAACTGTGC
TGCACTGCCCGAGCAGCTGCTGGAAAGCGAGCTTTTCGGCTATGAGCGCGGGGCGTTCACAGGCGGCAGGCGCGAGGGCA
AACAGGGGCTGTTTGAAGTGGCCCGGGGCGGAACTCTTTTTCTGGACGAGATAGGCGATATGCCGCTTGCATCGCAGGTG
AAAATCCTGCGCGTCATACAGGAAAGCAGAATGCGCCGGCTGGGAGGTTCGCAGGAAGTGGCGGTGGACACGCGCATTAT
AACCGCCACCAACAGAACTCTTGAGCGGCTGGTGGAAGAAGGACGCTTCCGGCAGGATTTGTATTACCGCATCAATGTGC
TGCCTATCCACATACCCCCGCTAAAAGAGCGGCTGGACGATATCCCGCTGCTGGTGGAGCATTTTTTGCTGAATCTCGCG
GCGCGGCTGGACAAGCCGGCGCGTTCGCTTACCCCCGATGCGCTGGACAAGCTGCGCGCGCATCATTGGCCGGGTAATGT
CCGGGAGTTGAAAAACGTTGTGGAGCGTGCGGCCATATTGTGTCAGGGGCAGATAGTGCGCCAGTCACATATACTTTTCA
GCCATGAAATTGAAGCCGGCATGTCGCGGCAGGCGTTACGGCAGGGGGCGCGTGTTGCCAGTACAGGACTGCGCGATGCT
GTGGCCGACTTTGAACGCGGTGTCATACGCGATGCTCTGACAAGAACGCCGAGTATCCGCAAGGCGGCGCAGGCTCTCGG
GGTTTCTCACTCCTCACTGCTGGCAAAAATGCGCAAACTGGGTGTCGGTTCGGTTTGA

Upstream 100 bases:

>100_bases
TTGTCCGGTAAAACGGTGTTTTACTGGCTTTGCTCTGCAGCGGGCACTTCCTGAGCCGCCTGGTGGCGGCTGATAATTCT
GTATCCGTAAACGGCATGGT

Downstream 100 bases:

>100_bases
TTTATGTCCAAATGGTTTGATTTTTGACCATCATGCACATGGTTATTTAAAACATACAGATAGTGCGTATGCTTTGTTTC
GCTGGTTTGTTTTTTTACCA

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MKLKLELIFKDRVGVVSDLSSLLAGHAFSISSMEVERKTDKAFVYIEAEKWDEAVERAALFKVLSRIPDLLEFRIVETLP
GEEREKRFKVVLDNISDGVLSIDARGRVTAINAVLRQVYGCGPDAAGKPLASLGLPDNGLLECLEGKELLNAKREIATSD
GRVQYFVTRRPIRDSNDRIVGAVELARDMREIRQLARSITDPEQIGFGDIVGRDAAIAFAISFAEQVAATDSIISIRGES
GTGKELFARAIHTASRRSGPFVPVNCAALPEQLLESELFGYERGAFTGGRREGKQGLFEVARGGTLFLDEIGDMPLASQV
KILRVIQESRMRRLGGSQEVAVDTRIITATNRTLERLVEEGRFRQDLYYRINVLPIHIPPLKERLDDIPLLVEHFLLNLA
ARLDKPARSLTPDALDKLRAHHWPGNVRELKNVVERAAILCQGQIVRQSHILFSHEIEAGMSRQALRQGARVASTGLRDA
VADFERGVIRDALTRTPSIRKAAQALGVSHSSLLAKMRKLGVGSV

Sequences:

>Translated_525_residues
MKLKLELIFKDRVGVVSDLSSLLAGHAFSISSMEVERKTDKAFVYIEAEKWDEAVERAALFKVLSRIPDLLEFRIVETLP
GEEREKRFKVVLDNISDGVLSIDARGRVTAINAVLRQVYGCGPDAAGKPLASLGLPDNGLLECLEGKELLNAKREIATSD
GRVQYFVTRRPIRDSNDRIVGAVELARDMREIRQLARSITDPEQIGFGDIVGRDAAIAFAISFAEQVAATDSIISIRGES
GTGKELFARAIHTASRRSGPFVPVNCAALPEQLLESELFGYERGAFTGGRREGKQGLFEVARGGTLFLDEIGDMPLASQV
KILRVIQESRMRRLGGSQEVAVDTRIITATNRTLERLVEEGRFRQDLYYRINVLPIHIPPLKERLDDIPLLVEHFLLNLA
ARLDKPARSLTPDALDKLRAHHWPGNVRELKNVVERAAILCQGQIVRQSHILFSHEIEAGMSRQALRQGARVASTGLRDA
VADFERGVIRDALTRTPSIRKAAQALGVSHSSLLAKMRKLGVGSV
>Mature_525_residues
MKLKLELIFKDRVGVVSDLSSLLAGHAFSISSMEVERKTDKAFVYIEAEKWDEAVERAALFKVLSRIPDLLEFRIVETLP
GEEREKRFKVVLDNISDGVLSIDARGRVTAINAVLRQVYGCGPDAAGKPLASLGLPDNGLLECLEGKELLNAKREIATSD
GRVQYFVTRRPIRDSNDRIVGAVELARDMREIRQLARSITDPEQIGFGDIVGRDAAIAFAISFAEQVAATDSIISIRGES
GTGKELFARAIHTASRRSGPFVPVNCAALPEQLLESELFGYERGAFTGGRREGKQGLFEVARGGTLFLDEIGDMPLASQV
KILRVIQESRMRRLGGSQEVAVDTRIITATNRTLERLVEEGRFRQDLYYRINVLPIHIPPLKERLDDIPLLVEHFLLNLA
ARLDKPARSLTPDALDKLRAHHWPGNVRELKNVVERAAILCQGQIVRQSHILFSHEIEAGMSRQALRQGARVASTGLRDA
VADFERGVIRDALTRTPSIRKAAQALGVSHSSLLAKMRKLGVGSV

Specific function: Unknown

COG id: COG3283

COG function: function code KE; Transcriptional regulator of aromatic amino acids metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=468, Percent_Identity=36.5384615384615, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1788550, Length=385, Percent_Identity=40.2597402597403, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI87082117, Length=367, Percent_Identity=42.7792915531335, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI1789087, Length=401, Percent_Identity=39.9002493765586, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1790437, Length=320, Percent_Identity=45.9375, Blast_Score=252, Evalue=4e-68,
Organism=Escherichia coli, GI1787583, Length=527, Percent_Identity=32.0683111954459, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1788905, Length=288, Percent_Identity=46.1805555555556, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI1790299, Length=334, Percent_Identity=40.7185628742515, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI1786524, Length=247, Percent_Identity=46.5587044534413, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI87082152, Length=279, Percent_Identity=43.3691756272401, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI87081872, Length=233, Percent_Identity=45.9227467811159, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI87081858, Length=446, Percent_Identity=28.9237668161435, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1789828, Length=223, Percent_Identity=37.6681614349776, Blast_Score=129, Evalue=4e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 58044; Mature: 58044

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4 ; PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKLELIFKDRVGVVSDLSSLLAGHAFSISSMEVERKTDKAFVYIEAEKWDEAVERAAL
CEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEEEEHHHHHHHHHHHHH
FKVLSRIPDLLEFRIVETLPGEEREKRFKVVLDNISDGVLSIDARGRVTAINAVLRQVYG
HHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHC
CGPDAAGKPLASLGLPDNGLLECLEGKELLNAKREIATSDGRVQYFVTRRPIRDSNDRIV
CCCCCCCCCHHHCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEE
GAVELARDMREIRQLARSITDPEQIGFGDIVGRDAAIAFAISFAEQVAATDSIISIRGES
HHHHHHHHHHHHHHHHHHCCCHHHCCCCHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCC
GTGKELFARAIHTASRRSGPFVPVNCAALPEQLLESELFGYERGAFTGGRREGKQGLFEV
CCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
ARGGTLFLDEIGDMPLASQVKILRVIQESRMRRLGGSQEVAVDTRIITATNRTLERLVEE
HCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHHC
GRFRQDLYYRINVLPIHIPPLKERLDDIPLLVEHFLLNLAARLDKPARSLTPDALDKLRA
CCCHHEEEEEEEEEEEECCHHHHHHCCHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHH
HHWPGNVRELKNVVERAAILCQGQIVRQSHILFSHEIEAGMSRQALRQGARVASTGLRDA
HCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHH
VADFERGVIRDALTRTPSIRKAAQALGVSHSSLLAKMRKLGVGSV
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKLKLELIFKDRVGVVSDLSSLLAGHAFSISSMEVERKTDKAFVYIEAEKWDEAVERAAL
CEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEEEEHHHHHHHHHHHHH
FKVLSRIPDLLEFRIVETLPGEEREKRFKVVLDNISDGVLSIDARGRVTAINAVLRQVYG
HHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHC
CGPDAAGKPLASLGLPDNGLLECLEGKELLNAKREIATSDGRVQYFVTRRPIRDSNDRIV
CCCCCCCCCHHHCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEE
GAVELARDMREIRQLARSITDPEQIGFGDIVGRDAAIAFAISFAEQVAATDSIISIRGES
HHHHHHHHHHHHHHHHHHCCCHHHCCCCHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCC
GTGKELFARAIHTASRRSGPFVPVNCAALPEQLLESELFGYERGAFTGGRREGKQGLFEV
CCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
ARGGTLFLDEIGDMPLASQVKILRVIQESRMRRLGGSQEVAVDTRIITATNRTLERLVEE
HCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHHC
GRFRQDLYYRINVLPIHIPPLKERLDDIPLLVEHFLLNLAARLDKPARSLTPDALDKLRA
CCCHHEEEEEEEEEEEECCHHHHHHCCHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHH
HHWPGNVRELKNVVERAAILCQGQIVRQSHILFSHEIEAGMSRQALRQGARVASTGLRDA
HCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHH
VADFERGVIRDALTRTPSIRKAAQALGVSHSSLLAKMRKLGVGSV
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA