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The map label for this gene is accD [H]

Identifier: 78356585

GI number: 78356585

Start: 1560718

End: 1562982

Strand: Direct

Name: accD [H]

Synonym: Dde_1542

Alternate gene names: 78356585

Gene position: 1560718-1562982 (Clockwise)

Preceding gene: 78356584

Following gene: 78356586

Centisome position: 41.84

GC content: 56.07

Gene sequence:

>2265_bases
ATGGATTTTGATAAGAAACTGCATCAGCTTAACGACCGTCTCAACTACATCCGGGACGTGTTTACCGGCAAGCAGGAAGA
AAATATCCGCCTGCTTGAGAGCAAGCTGAATGAATTGATGCTGAGGGAAAAGCACCTTTCCGCTTCGGAACAGCAGGCTG
CCGCAGCCACGGTTGACGATCTGTTCGACTTTGTGGAGCGCAAGCTTGAAGAAGATCTTACCCCCATGGACAGGGTGCGT
ATCGTACGTCATTCGCAGCGGGTCTGCCTGCGCGACGTGCTTGAAAATGTGTACGACAACTACACCGAGATAGGCGGCAA
GGACGAGAACAGTATCGATCCGAGCATGCTTATTGCGCGTGCCTACATCACAAGGCGCAGCGGTAAAAAGGTGTACCACC
AGCCGGTGATGGTCATAGGGCAGGAAAAAGGCCATGGAGAGGAATTCCGCAACGGCGGTTCTGTAAAGCCCTGGGGCAAT
GCCAAGGCCCTGCACTATATGAAAGTTGCCGAAACAGAAAATATTCCCATCCATACATATGTGTTCACACCCGGATCATA
TCCGGTGGAGGATGCTCCCGGAGCTGCCCAGCAGATAGCCCGCAACCTGTACGAAATGGCAGGGCTGCGTGTGCCTGTTG
TGGCCGTGTTTTCCGAAGGTGGCTCCGGCGGTGCCGAAGCCATCGGGCTGGCCGATACCCGGCTCATGCTCTCCCACGGG
TACTATTCTGTTATTTCTCCCGAAGGGGCGGCCGCCATCGAAGGCAGGCTCAAAGAAGGCCAGCGTGCCACGCCGGAACT
GATTGAAAAATGCGCGCGCCAGCTGCGTATCACCGCTGCGGATAACCGCCGCATGGGGTACATTGATCACGTTATAGACG
AGCCGCCGCTGGGAGCCAGACCGTACCATTACGATTTTTTCCGTTCTTTGCGGCAGGAAGTTATCCGCGCGACGGATGAG
GTTGTGCTGGGGGTCAAGGGGTTTGCTCCTTTCCGCGCCATGGCTTTACGCAGGCGGCACGGCAAAAAGGGTGTGACGCC
TGACTTTGACAATATCTATGTCCGCTGGAATCTTTCTTCCAACGCCCGTGACAGACTGGTGATGAAACGCCACCGCAAGT
TCCGCCGCCTGTCACGTCAGGCGTGTCTGGACAGACGCGCCGTGCACCGCAGAATATGGGAATGGGGATATGATCTCGGC
TGGGATGTTTATTCTTATTTCAAGTACGACCTGTGGCGTAAGCATCAGCAGCGCATTGTTTATGCGGTGGAAGAGGTGGA
CGCTGAAGCGCGTGTGCTGATGAACCGCCTGCTGAGCCCGTGGCGTAAGCTGAGCGGGTCACTGCCCGGTTCCGGCAAGC
CTGCCGAGGACAAAGAAAAAGAGCTGACCATGCTTTCGCAGTGGGATCAGGAAGACCAGCGCAACGGCGAATGGCGCTAT
GTAAGCCCGCGTGCCAAGGAAGACCGCACCATTACCTGCCCCAATGCGGATTCTCATGGCTGCCTTGACCTGTGGGCCCC
TGATCTTTTTGGCGAATTTGCCGGTGTGTGCAACTATTGCGGGCATCATTTTCCGATGGAAAGCAAGTGGTTCGTGCATA
ATATCTTTGATAACGGCTCTGTTTTCGAGTTCAACTCCGAGCTGGAAGCCGCCAACCCGCTGGGTTTTGAAGGGCTGGAC
GTGAAGCTGGATCAGGCCAAGCAGAAAACCGGCCAGAAGTCCGGCTGCGTCACGTTCGAAGCGCGGCTCGATAATATCAA
GATAGTGGTTGCCATGCTTACCGCACCGTTCCGCGGTGGGTCGGTGGGTGCCGCCGAAGGCGAAAAGTTTATCCGCGCCG
CTGAGCGGGCCAAGAAAAAGCGTTTTCCGTTTCTTGCCTATGTGCACGGCACTGCCGGTATCCGCATTCAGGAAGGCACC
AACGGAGTCATCCAGATGCCCCGCTGCACCATGGCCGTGCGCCGGTACATCGAAGAAGGCGGGCTGTACCTTGTGGTTTA
TGACACCAATTCCTACGCCGGCCCTCTGGCAAGCTTTCTCGGCTGTTCGCCGTATCAGTTTGCCATCCGTTCTGCCAACA
TAGGCTTTGCGGGCAGAGGGGTTATCAAGGAAACGACCGGTATGGATATTCCTCCTGACTACCACAATGCCTTCAAGGCA
CTGAGCAGAGGACATATTCAGGGCATATGGGACCGCAGAGAAGCGCGGCAGAATCTGCGCCAGGCACTGCTGACCATGGG
CGGACGCAATCTTTATTACCGCTAG

Upstream 100 bases:

>100_bases
CGCCGCGCGGTTGCCCGCGCTGTGCGGACTCTGCACGGCATGCCGTATGCGGCTGCCGTAGCCCAACAAGGCAATATCCC
CGCAAGCGGGGAGGAGCGAT

Downstream 100 bases:

>100_bases
CCGTCAACCGGCCGCGGGGCCGAACGAAGCAAGGAAACGGGTGAAAAACCGTGCTTGATATATCACAACTGCTTGAAGAG
ATTAAGGCGTCTCCTTATCA

Product: Acetyl-CoA carboxylase

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 754; Mature: 754

Protein sequence:

>754_residues
MDFDKKLHQLNDRLNYIRDVFTGKQEENIRLLESKLNELMLREKHLSASEQQAAAATVDDLFDFVERKLEEDLTPMDRVR
IVRHSQRVCLRDVLENVYDNYTEIGGKDENSIDPSMLIARAYITRRSGKKVYHQPVMVIGQEKGHGEEFRNGGSVKPWGN
AKALHYMKVAETENIPIHTYVFTPGSYPVEDAPGAAQQIARNLYEMAGLRVPVVAVFSEGGSGGAEAIGLADTRLMLSHG
YYSVISPEGAAAIEGRLKEGQRATPELIEKCARQLRITAADNRRMGYIDHVIDEPPLGARPYHYDFFRSLRQEVIRATDE
VVLGVKGFAPFRAMALRRRHGKKGVTPDFDNIYVRWNLSSNARDRLVMKRHRKFRRLSRQACLDRRAVHRRIWEWGYDLG
WDVYSYFKYDLWRKHQQRIVYAVEEVDAEARVLMNRLLSPWRKLSGSLPGSGKPAEDKEKELTMLSQWDQEDQRNGEWRY
VSPRAKEDRTITCPNADSHGCLDLWAPDLFGEFAGVCNYCGHHFPMESKWFVHNIFDNGSVFEFNSELEAANPLGFEGLD
VKLDQAKQKTGQKSGCVTFEARLDNIKIVVAMLTAPFRGGSVGAAEGEKFIRAAERAKKKRFPFLAYVHGTAGIRIQEGT
NGVIQMPRCTMAVRRYIEEGGLYLVVYDTNSYAGPLASFLGCSPYQFAIRSANIGFAGRGVIKETTGMDIPPDYHNAFKA
LSRGHIQGIWDRREARQNLRQALLTMGGRNLYYR

Sequences:

>Translated_754_residues
MDFDKKLHQLNDRLNYIRDVFTGKQEENIRLLESKLNELMLREKHLSASEQQAAAATVDDLFDFVERKLEEDLTPMDRVR
IVRHSQRVCLRDVLENVYDNYTEIGGKDENSIDPSMLIARAYITRRSGKKVYHQPVMVIGQEKGHGEEFRNGGSVKPWGN
AKALHYMKVAETENIPIHTYVFTPGSYPVEDAPGAAQQIARNLYEMAGLRVPVVAVFSEGGSGGAEAIGLADTRLMLSHG
YYSVISPEGAAAIEGRLKEGQRATPELIEKCARQLRITAADNRRMGYIDHVIDEPPLGARPYHYDFFRSLRQEVIRATDE
VVLGVKGFAPFRAMALRRRHGKKGVTPDFDNIYVRWNLSSNARDRLVMKRHRKFRRLSRQACLDRRAVHRRIWEWGYDLG
WDVYSYFKYDLWRKHQQRIVYAVEEVDAEARVLMNRLLSPWRKLSGSLPGSGKPAEDKEKELTMLSQWDQEDQRNGEWRY
VSPRAKEDRTITCPNADSHGCLDLWAPDLFGEFAGVCNYCGHHFPMESKWFVHNIFDNGSVFEFNSELEAANPLGFEGLD
VKLDQAKQKTGQKSGCVTFEARLDNIKIVVAMLTAPFRGGSVGAAEGEKFIRAAERAKKKRFPFLAYVHGTAGIRIQEGT
NGVIQMPRCTMAVRRYIEEGGLYLVVYDTNSYAGPLASFLGCSPYQFAIRSANIGFAGRGVIKETTGMDIPPDYHNAFKA
LSRGHIQGIWDRREARQNLRQALLTMGGRNLYYR
>Mature_754_residues
MDFDKKLHQLNDRLNYIRDVFTGKQEENIRLLESKLNELMLREKHLSASEQQAAAATVDDLFDFVERKLEEDLTPMDRVR
IVRHSQRVCLRDVLENVYDNYTEIGGKDENSIDPSMLIARAYITRRSGKKVYHQPVMVIGQEKGHGEEFRNGGSVKPWGN
AKALHYMKVAETENIPIHTYVFTPGSYPVEDAPGAAQQIARNLYEMAGLRVPVVAVFSEGGSGGAEAIGLADTRLMLSHG
YYSVISPEGAAAIEGRLKEGQRATPELIEKCARQLRITAADNRRMGYIDHVIDEPPLGARPYHYDFFRSLRQEVIRATDE
VVLGVKGFAPFRAMALRRRHGKKGVTPDFDNIYVRWNLSSNARDRLVMKRHRKFRRLSRQACLDRRAVHRRIWEWGYDLG
WDVYSYFKYDLWRKHQQRIVYAVEEVDAEARVLMNRLLSPWRKLSGSLPGSGKPAEDKEKELTMLSQWDQEDQRNGEWRY
VSPRAKEDRTITCPNADSHGCLDLWAPDLFGEFAGVCNYCGHHFPMESKWFVHNIFDNGSVFEFNSELEAANPLGFEGLD
VKLDQAKQKTGQKSGCVTFEARLDNIKIVVAMLTAPFRGGSVGAAEGEKFIRAAERAKKKRFPFLAYVHGTAGIRIQEGT
NGVIQMPRCTMAVRRYIEEGGLYLVVYDTNSYAGPLASFLGCSPYQFAIRSANIGFAGRGVIKETTGMDIPPDYHNAFKA
LSRGHIQGIWDRREARQNLRQALLTMGGRNLYYR

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=323, Percent_Identity=32.8173374613003, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1788655, Length=231, Percent_Identity=31.6017316017316, Blast_Score=119, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 85837; Mature: 85837

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFDKKLHQLNDRLNYIRDVFTGKQEENIRLLESKLNELMLREKHLSASEQQAAAATVDD
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LFDFVERKLEEDLTPMDRVRIVRHSQRVCLRDVLENVYDNYTEIGGKDENSIDPSMLIAR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
AYITRRSGKKVYHQPVMVIGQEKGHGEEFRNGGSVKPWGNAKALHYMKVAETENIPIHTY
HHHHHCCCCHHHHCCEEEEECCCCCCHHHCCCCCCCCCCCCCCEEEEEECCCCCCCEEEE
VFTPGSYPVEDAPGAAQQIARNLYEMAGLRVPVVAVFSEGGSGGAEAIGLADTRLMLSHG
EECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEHHHHHHHHHCC
YYSVISPEGAAAIEGRLKEGQRATPELIEKCARQLRITAADNRRMGYIDHVIDEPPLGAR
CEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHEEEEECCCCCCCHHHHHCCCCCCCCC
PYHYDFFRSLRQEVIRATDEVVLGVKGFAPFRAMALRRRHGKKGVTPDFDNIYVRWNLSS
CCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCC
NARDRLVMKRHRKFRRLSRQACLDRRAVHRRIWEWGYDLGWDVYSYFKYDLWRKHQQRIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
YAVEEVDAEARVLMNRLLSPWRKLSGSLPGSGKPAEDKEKELTMLSQWDQEDQRNGEWRY
HHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCEEE
VSPRAKEDRTITCPNADSHGCLDLWAPDLFGEFAGVCNYCGHHFPMESKWFVHNIFDNGS
ECCCCCCCCEEECCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
VFEFNSELEAANPLGFEGLDVKLDQAKQKTGQKSGCVTFEARLDNIKIVVAMLTAPFRGG
EEEECCCCCCCCCCCCCCCCEEHHHHHHHCCCCCCCEEEEEECCCCEEEEEEHHCCCCCC
SVGAAEGEKFIRAAERAKKKRFPFLAYVHGTAGIRIQEGTNGVIQMPRCTMAVRRYIEEG
CCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCEEECCHHHHHHHHHHHHC
GLYLVVYDTNSYAGPLASFLGCSPYQFAIRSANIGFAGRGVIKETTGMDIPPDYHNAFKA
CEEEEEECCCCCCHHHHHHHCCCCHHHEEEECCCCCCCCCCEECCCCCCCCCCHHHHHHH
LSRGHIQGIWDRREARQNLRQALLTMGGRNLYYR
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDFDKKLHQLNDRLNYIRDVFTGKQEENIRLLESKLNELMLREKHLSASEQQAAAATVDD
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LFDFVERKLEEDLTPMDRVRIVRHSQRVCLRDVLENVYDNYTEIGGKDENSIDPSMLIAR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
AYITRRSGKKVYHQPVMVIGQEKGHGEEFRNGGSVKPWGNAKALHYMKVAETENIPIHTY
HHHHHCCCCHHHHCCEEEEECCCCCCHHHCCCCCCCCCCCCCCEEEEEECCCCCCCEEEE
VFTPGSYPVEDAPGAAQQIARNLYEMAGLRVPVVAVFSEGGSGGAEAIGLADTRLMLSHG
EECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEHHHHHHHHHCC
YYSVISPEGAAAIEGRLKEGQRATPELIEKCARQLRITAADNRRMGYIDHVIDEPPLGAR
CEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHEEEEECCCCCCCHHHHHCCCCCCCCC
PYHYDFFRSLRQEVIRATDEVVLGVKGFAPFRAMALRRRHGKKGVTPDFDNIYVRWNLSS
CCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCC
NARDRLVMKRHRKFRRLSRQACLDRRAVHRRIWEWGYDLGWDVYSYFKYDLWRKHQQRIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
YAVEEVDAEARVLMNRLLSPWRKLSGSLPGSGKPAEDKEKELTMLSQWDQEDQRNGEWRY
HHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCEEE
VSPRAKEDRTITCPNADSHGCLDLWAPDLFGEFAGVCNYCGHHFPMESKWFVHNIFDNGS
ECCCCCCCCEEECCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
VFEFNSELEAANPLGFEGLDVKLDQAKQKTGQKSGCVTFEARLDNIKIVVAMLTAPFRGG
EEEECCCCCCCCCCCCCCCCEEHHHHHHHCCCCCCCEEEEEECCCCEEEEEEHHCCCCCC
SVGAAEGEKFIRAAERAKKKRFPFLAYVHGTAGIRIQEGTNGVIQMPRCTMAVRRYIEEG
CCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCEEECCHHHHHHHHHHHHC
GLYLVVYDTNSYAGPLASFLGCSPYQFAIRSANIGFAGRGVIKETTGMDIPPDYHNAFKA
CEEEEEECCCCCCHHHHHHHCCCCHHHEEEECCCCCCCCCCEECCCCCCCCCCHHHHHHH
LSRGHIQGIWDRREARQNLRQALLTMGGRNLYYR
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA