Click here to switch to the map view.

The map label for this gene is hmp [H]

Identifier: 78356426

GI number: 78356426

Start: 1399065

End: 1399988

Strand: Reverse

Name: hmp [H]

Synonym: Dde_1381

Alternate gene names: 78356426

Gene position: 1399988-1399065 (Counterclockwise)

Preceding gene: 78356441

Following gene: 78356409

Centisome position: 37.53

GC content: 54.55

Gene sequence:

>924_bases
TTGCGTAGCCGCTCACTATACAATCGGGTGCAGAATACCGCATCATGGTGCAAGAGCAATACTTTTTTCCCTGATTTTTC
CTTTCCGGCGTCGTGCGGGGGCTGGACACCCCCGCCCCGTTGGTTCACTATAAAAAAAACAAATCCCCATCATGACAGCC
ACGGAGAACGCATGAGCGATACCGGCAAAAATAAACTTGGTGTCATTGTCGACACCGTACGCGAAAACGACGACACCACG
AGCATATTCTTCCGGCCCGAAGATGACGAACGCTTCAAGGCATTCAGACCCGGACAATTCGCATCCATACGGGTGATGAC
CGAAGAAGGATGGAGTGAACCGCATCCGTTTACCATATCAGGAGCTCCGGGCGATACGCTGCGCATGACCATCAAACGCA
ACGGCCGTTTTACCGGCGAAATCATTCCCGCGCTCAAGGCAGGCGTGCCCATCCAGTGTGCCGGACCGTTCGGGGCTTTC
TGCCGCGATATCGAAGGGGAAGAACAGATCGTATTTGTGGCGGGCGGCGTGGGCATAACACCGTTTCTCAGCGTGTTACG
CCATTTTCGCAATACTGACGCCGCCAACAGCATAGTGCTTTTCTGGTGCAACAAAACCTACGCGGACGCGTTTGCCGCGC
AGGAGCTGGAAGAGATTGCGGATACAATTGATCTGACGGTGGTGCATGTGCTCAGCCGTGAGCACAAACCCGATCTGTAC
GAAGAAGAGGACAAGCCCCGCATCCGTTTTGAAAAAGGGCACTTTTCGCGCCATATGCTGGAACGGCACATCCGTTCCAC
CACGGCGTCGTTTTATCTGTGCGGTCCGGGCCCCATGCAGGAGCATGTTCTGGACGAGATGGCCGCCTACGGCATAGACC
CTGCAGGAGTGAACAAGGAACAGTTCGTCTTTACGGGAAAATAG

Upstream 100 bases:

>100_bases
AACCAGGGGACAACGCTTTGCGCAACGCTGTCCAGTCCGCTTTTGACCGACTCCAGAACACGGTCTGTCTCTGATGCGTG
CCTAGCCATGCAGTTCCTCC

Downstream 100 bases:

>100_bases
CAGGCATGCCCTGCGGCGGCCTTTTTCTCCGCCGCCGCGCACGGGATGCGCGCCTGCACGCAACGCACCCCGCGCCGTTA
CAACATGGCATGCACAACAT

Product: ferric reductase-like

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MRSRSLYNRVQNTASWCKSNTFFPDFSFPASCGGWTPPPRWFTIKKTNPHHDSHGERMSDTGKNKLGVIVDTVRENDDTT
SIFFRPEDDERFKAFRPGQFASIRVMTEEGWSEPHPFTISGAPGDTLRMTIKRNGRFTGEIIPALKAGVPIQCAGPFGAF
CRDIEGEEQIVFVAGGVGITPFLSVLRHFRNTDAANSIVLFWCNKTYADAFAAQELEEIADTIDLTVVHVLSREHKPDLY
EEEDKPRIRFEKGHFSRHMLERHIRSTTASFYLCGPGPMQEHVLDEMAAYGIDPAGVNKEQFVFTGK

Sequences:

>Translated_307_residues
MRSRSLYNRVQNTASWCKSNTFFPDFSFPASCGGWTPPPRWFTIKKTNPHHDSHGERMSDTGKNKLGVIVDTVRENDDTT
SIFFRPEDDERFKAFRPGQFASIRVMTEEGWSEPHPFTISGAPGDTLRMTIKRNGRFTGEIIPALKAGVPIQCAGPFGAF
CRDIEGEEQIVFVAGGVGITPFLSVLRHFRNTDAANSIVLFWCNKTYADAFAAQELEEIADTIDLTVVHVLSREHKPDLY
EEEDKPRIRFEKGHFSRHMLERHIRSTTASFYLCGPGPMQEHVLDEMAAYGIDPAGVNKEQFVFTGK
>Mature_307_residues
MRSRSLYNRVQNTASWCKSNTFFPDFSFPASCGGWTPPPRWFTIKKTNPHHDSHGERMSDTGKNKLGVIVDTVRENDDTT
SIFFRPEDDERFKAFRPGQFASIRVMTEEGWSEPHPFTISGAPGDTLRMTIKRNGRFTGEIIPALKAGVPIQCAGPFGAF
CRDIEGEEQIVFVAGGVGITPFLSVLRHFRNTDAANSIVLFWCNKTYADAFAAQELEEIADTIDLTVVHVLSREHKPDLY
EEEDKPRIRFEKGHFSRHMLERHIRSTTASFYLCGPGPMQEHVLDEMAAYGIDPAGVNKEQFVFTGK

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 34669; Mature: 34669

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSRSLYNRVQNTASWCKSNTFFPDFSFPASCGGWTPPPRWFTIKKTNPHHDSHGERMSD
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHH
TGKNKLGVIVDTVRENDDTTSIFFRPEDDERFKAFRPGQFASIRVMTEEGWSEPHPFTIS
CCCCCEEEEEEEECCCCCCEEEEEECCCCCHHHCCCCCCCEEEEEEECCCCCCCCCEEEE
GAPGDTLRMTIKRNGRFTGEIIPALKAGVPIQCAGPFGAFCRDIEGEEQIVFVAGGVGIT
CCCCCEEEEEEECCCCCCCEEHHHHHCCCCEEECCCHHHHHHCCCCCCEEEEEECCCCHH
PFLSVLRHFRNTDAANSIVLFWCNKTYADAFAAQELEEIADTIDLTVVHVLSREHKPDLY
HHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EEEDKPRIRFEKGHFSRHMLERHIRSTTASFYLCGPGPMQEHVLDEMAAYGIDPAGVNKE
CCCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCC
QFVFTGK
CEEEECC
>Mature Secondary Structure
MRSRSLYNRVQNTASWCKSNTFFPDFSFPASCGGWTPPPRWFTIKKTNPHHDSHGERMSD
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHH
TGKNKLGVIVDTVRENDDTTSIFFRPEDDERFKAFRPGQFASIRVMTEEGWSEPHPFTIS
CCCCCEEEEEEEECCCCCCEEEEEECCCCCHHHCCCCCCCEEEEEEECCCCCCCCCEEEE
GAPGDTLRMTIKRNGRFTGEIIPALKAGVPIQCAGPFGAFCRDIEGEEQIVFVAGGVGIT
CCCCCEEEEEEECCCCCCCEEHHHHHCCCCEEECCCHHHHHHCCCCCCEEEEEECCCCHH
PFLSVLRHFRNTDAANSIVLFWCNKTYADAFAAQELEEIADTIDLTVVHVLSREHKPDLY
HHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EEEDKPRIRFEKGHFSRHMLERHIRSTTASFYLCGPGPMQEHVLDEMAAYGIDPAGVNKE
CCCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCC
QFVFTGK
CEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]