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The map label for this gene is fabZ

Identifier: 78356420

GI number: 78356420

Start: 1393365

End: 1393829

Strand: Direct

Name: fabZ

Synonym: Dde_1373

Alternate gene names: 78356420

Gene position: 1393365-1393829 (Clockwise)

Preceding gene: 78356419

Following gene: 78356421

Centisome position: 37.35

GC content: 53.76

Gene sequence:

>465_bases
ATGAACGACAAGGCGAAAAGCATTTTGGATATTCGACAGATTCTGGGACTGCTGCCGCACCGGTATCCTTTTCTGCTGGT
GGACAGAGTGCTCGACTACACCCCCGGCGAGTGCATTACCGCTGTAAAAAACGTCACCATGAACGAGCCTTTTTTTCAGG
GGCATTTTCCTGATGTGCCGGTAATGCCCGGCGTGCTCATTATGGAAGCGCTTGCGCAGGCCGGTGGCATTCTGGTGGTC
AAAAGCACCGACACCAGCGTGGAAGGTAAGCTTTTTCTGTTTACAGGCATGGAAAGAGTGCGCTTCAGAAAGCCGGTATA
CCCCGGCGACAGGCTGGAGCTGCATTGCCGCCTTTTGCGCCACAAGCTAAAGCTGTGGAAGATGGAAGGCAAAGCCTATG
TGGACGGACAGCTTGCTGCCGAAGCCGAAATGACCGCCGCTGTCATGAACAGAGAGGATATGTAG

Upstream 100 bases:

>100_bases
CACTGACGGTGATGCCTAAACTGCCTGACATGTACAAGCGGCTGAGAAAATTAGAAAAAGAGCTTGAGGCGCTGAAAGGC
GAATCAGGCAGGGATAGCTG

Downstream 100 bases:

>100_bases
CGTGGCTGCGCAGATTCATCCTTCCGCCTTTGTGGACAGCAAGGCCGTTATCGGAGAAGACGTTGTCATCGGGCCGTGCG
CCGTTGTCGAGGCAAACACC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MNDKAKSILDIRQILGLLPHRYPFLLVDRVLDYTPGECITAVKNVTMNEPFFQGHFPDVPVMPGVLIMEALAQAGGILVV
KSTDTSVEGKLFLFTGMERVRFRKPVYPGDRLELHCRLLRHKLKLWKMEGKAYVDGQLAAEAEMTAAVMNREDM

Sequences:

>Translated_154_residues
MNDKAKSILDIRQILGLLPHRYPFLLVDRVLDYTPGECITAVKNVTMNEPFFQGHFPDVPVMPGVLIMEALAQAGGILVV
KSTDTSVEGKLFLFTGMERVRFRKPVYPGDRLELHCRLLRHKLKLWKMEGKAYVDGQLAAEAEMTAAVMNREDM
>Mature_154_residues
MNDKAKSILDIRQILGLLPHRYPFLLVDRVLDYTPGECITAVKNVTMNEPFFQGHFPDVPVMPGVLIMEALAQAGGILVV
KSTDTSVEGKLFLFTGMERVRFRKPVYPGDRLELHCRLLRHKLKLWKMEGKAYVDGQLAAEAEMTAAVMNREDM

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=51.7985611510791, Blast_Score=150, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_DESDG (Q312H2)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_387869.1
- ProteinModelPortal:   Q312H2
- SMR:   Q312H2
- STRING:   Q312H2
- GeneID:   3756160
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1373
- NMPDR:   fig|207559.3.peg.1747
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   DDES207559:DDE_1373-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 17432; Mature: 17432

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: ACT_SITE 55-55

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDKAKSILDIRQILGLLPHRYPFLLVDRVLDYTPGECITAVKNVTMNEPFFQGHFPDVP
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
VMPGVLIMEALAQAGGILVVKSTDTSVEGKLFLFTGMERVRFRKPVYPGDRLELHCRLLR
CCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECHHHHHHCCCCCCCCHHHHHHHHHH
HKLKLWKMEGKAYVDGQLAAEAEMTAAVMNREDM
HHHHHHHCCCCEEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNDKAKSILDIRQILGLLPHRYPFLLVDRVLDYTPGECITAVKNVTMNEPFFQGHFPDVP
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
VMPGVLIMEALAQAGGILVVKSTDTSVEGKLFLFTGMERVRFRKPVYPGDRLELHCRLLR
CCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECHHHHHHCCCCCCCCHHHHHHHHHH
HKLKLWKMEGKAYVDGQLAAEAEMTAAVMNREDM
HHHHHHHCCCCEEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA