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The map label for this gene is lpxA [H]

Identifier: 78356421

GI number: 78356421

Start: 1393831

End: 1394616

Strand: Direct

Name: lpxA [H]

Synonym: Dde_1374

Alternate gene names: 78356421

Gene position: 1393831-1394616 (Clockwise)

Preceding gene: 78356420

Following gene: 78356422

Centisome position: 37.37

GC content: 59.29

Gene sequence:

>786_bases
GTGGCTGCGCAGATTCATCCTTCCGCCTTTGTGGACAGCAAGGCCGTTATCGGAGAAGACGTTGTCATCGGGCCGTGCGC
CGTTGTCGAGGCAAACACCGTCATCGGCGACCGTTGCCGCATTGATGCCTTTGCTTCGGTCAAGCAGTATACCCGCATGG
GAACGGACAACCATATCTATTCCTATGCCGCCGTGGGCGGCGAACCGCAGGATCTCAAGTTTCACGGTGAGGAATCGTGG
CTTGAGATAGGCGACCGCAACCGTATACGCGAGTTTGCCACTCTGCACCGCGGAACCGAAGGCGGAGGCGCAAAGACCGT
GGTGGGCAGTGATAACCTGCTTATGGCCTATACTCATGTGGCGCATGACTGCCACGTGAAAGACGGCATCATCATGTCCA
ACGGCGCCACTCTGGCGGGGCACGTGACCGTGGAAGACCATGCCATTCTGGCCGGTCTTTCAGCTGTGCATCAGTTTGTG
CGCATCGGCCGCAACGCCTTTGTGGGCGGTATGAGCGGCATCGCGCAGGACCTGCCGCCCTTTATGCTGGCCGTGGGCAA
CCGCGCCGGCGTGCACGGGCCCAATCTTGTCGGGCTGCGCCGGGCAAAGGCTTCCCGCGATCTCATAGCGGCGCTGAAAA
GCGCTTACCGGCTGATCTGGCATTCCGAAACTCCCCGTAAGGAGGCCTTGGAACAGCTGGAATACGAGTATGGAAACTTC
CCTGAAGTGCTCAATTTTGTGGAGTTTATCCGCAGCAGCGAGCGGGGGATTCTGTCCGTGGAATAG

Upstream 100 bases:

>100_bases
CTAAAGCTGTGGAAGATGGAAGGCAAAGCCTATGTGGACGGACAGCTTGCTGCCGAAGCCGAAATGACCGCCGCTGTCAT
GAACAGAGAGGATATGTAGC

Downstream 100 bases:

>100_bases
TACACGGCCGGTCAACTGAAATACCAAGCAGGGGAAAGCGGGCACGGCCTTCTTTCCCCTGTTTTGTCTGCACACGGTCG
CATCGCCGCCGTGTGCGGCG

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MAAQIHPSAFVDSKAVIGEDVVIGPCAVVEANTVIGDRCRIDAFASVKQYTRMGTDNHIYSYAAVGGEPQDLKFHGEESW
LEIGDRNRIREFATLHRGTEGGGAKTVVGSDNLLMAYTHVAHDCHVKDGIIMSNGATLAGHVTVEDHAILAGLSAVHQFV
RIGRNAFVGGMSGIAQDLPPFMLAVGNRAGVHGPNLVGLRRAKASRDLIAALKSAYRLIWHSETPRKEALEQLEYEYGNF
PEVLNFVEFIRSSERGILSVE

Sequences:

>Translated_261_residues
MAAQIHPSAFVDSKAVIGEDVVIGPCAVVEANTVIGDRCRIDAFASVKQYTRMGTDNHIYSYAAVGGEPQDLKFHGEESW
LEIGDRNRIREFATLHRGTEGGGAKTVVGSDNLLMAYTHVAHDCHVKDGIIMSNGATLAGHVTVEDHAILAGLSAVHQFV
RIGRNAFVGGMSGIAQDLPPFMLAVGNRAGVHGPNLVGLRRAKASRDLIAALKSAYRLIWHSETPRKEALEQLEYEYGNF
PEVLNFVEFIRSSERGILSVE
>Mature_260_residues
AAQIHPSAFVDSKAVIGEDVVIGPCAVVEANTVIGDRCRIDAFASVKQYTRMGTDNHIYSYAAVGGEPQDLKFHGEESWL
EIGDRNRIREFATLHRGTEGGGAKTVVGSDNLLMAYTHVAHDCHVKDGIIMSNGATLAGHVTVEDHAILAGLSAVHQFVR
IGRNAFVGGMSGIAQDLPPFMLAVGNRAGVHGPNLVGLRRAKASRDLIAALKSAYRLIWHSETPRKEALEQLEYEYGNFP
EVLNFVEFIRSSERGILSVE

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=257, Percent_Identity=46.3035019455253, Blast_Score=233, Evalue=7e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28306; Mature: 28175

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAQIHPSAFVDSKAVIGEDVVIGPCAVVEANTVIGDRCRIDAFASVKQYTRMGTDNHIY
CCCCCCCHHHCCCCHHCCCCEEECCEEEEECCCEECCCCCHHHHHHHHHHHHCCCCCCEE
SYAAVGGEPQDLKFHGEESWLEIGDRNRIREFATLHRGTEGGGAKTVVGSDNLLMAYTHV
EEEECCCCCCCEEECCCCHHEECCCHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEEHH
AHDCHVKDGIIMSNGATLAGHVTVEDHAILAGLSAVHQFVRIGRNAFVGGMSGIAQDLPP
HHHCCCCCCEEEECCCEEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHCCH
FMLAVGNRAGVHGPNLVGLRRAKASRDLIAALKSAYRLIWHSETPRKEALEQLEYEYGNF
HHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
PEVLNFVEFIRSSERGILSVE
HHHHHHHHHHHCCCCCEEEEC
>Mature Secondary Structure 
AAQIHPSAFVDSKAVIGEDVVIGPCAVVEANTVIGDRCRIDAFASVKQYTRMGTDNHIY
CCCCCCHHHCCCCHHCCCCEEECCEEEEECCCEECCCCCHHHHHHHHHHHHCCCCCCEE
SYAAVGGEPQDLKFHGEESWLEIGDRNRIREFATLHRGTEGGGAKTVVGSDNLLMAYTHV
EEEECCCCCCCEEECCCCHHEECCCHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEEHH
AHDCHVKDGIIMSNGATLAGHVTVEDHAILAGLSAVHQFVRIGRNAFVGGMSGIAQDLPP
HHHCCCCCCEEEECCCEEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHCCH
FMLAVGNRAGVHGPNLVGLRRAKASRDLIAALKSAYRLIWHSETPRKEALEQLEYEYGNF
HHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
PEVLNFVEFIRSSERGILSVE
HHHHHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA