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The map label for this gene is macB [H]

Identifier: 78356383

GI number: 78356383

Start: 1354150

End: 1355514

Strand: Reverse

Name: macB [H]

Synonym: Dde_1336

Alternate gene names: 78356383

Gene position: 1355514-1354150 (Counterclockwise)

Preceding gene: 78356384

Following gene: 78356382

Centisome position: 36.34

GC content: 60.0

Gene sequence:

>1365_bases
GTGAAGTCACACCCGCACACCATATCCGGTTCGTCTGATTCTGTTCCCTCGGCGGGCACGGGGGCGCTGTCCGGTCCGCC
GGATTCTCCGGCGCAGACACCGGCGCAGACACGGGCGCTGCACCGGCGCGTCATCCACGCGGCACGGGTTTTGTGGCGCA
TACAGCATATCGCCTTTACGGCTGTATGGGCGCATCGCCTGCGCAGTGCGTTTGTGGTCACGGCCATTGCACTGGGCATA
GCCTCGCTGACGGTCATCATAGCGGCAGTGGACGGTGCACAAAAAAAAGCGCTCGAAATCACCAAAGAATTCGGCCCGGA
TGCCGCCCTGATTTTCGGGGGCGACATTTTCAACCGTGCAGTGGGACAGCGGCTTACCACCCTGACCCCTCATGACGCCC
GCAGTATCCGGCAGATGCTGCCCGGTGTATATCTGGTGGTGCCCATGCGCTCCAAGCGCGGCATCACGGCCAAAGCAAAC
GGCAACAACGCCGAAGTTGAACGCATTGTCGGGGCAACGGCAAACTATGCGGAAGCATGGAACTGGCCGCTTTCACAAGG
CCGCGACTTCACTCAGGCCGATGTGGACAGAGGCGCACGGGTATGTCTGCTGGGTGTCGATCCCCGCGACAAACTGTTTG
CCGGTGTTCCGCCGCTGGGCCGCACCGTGTTTCTCAACAACATCCCCTTCACCGTGGTGGGCGTACTGAGCAAACGCGGC
ACAAGTTCCCCCAATGCTCGGCTTGATGACCGCATTATTGTACCGCTGACAACACTGACCCAGCGCTTTAATATGGACAG
GCGCCACTTTCCCGCCCTGCGGGTGAAATTCACCAATGCCGAAGCCATGGACGAGCACAAAGAGGGGCTTAAAAGCCTGC
TGCGCCACCTGCACAACCTGCGTCCCGGCGACCCCGACGACTTTTCCATCATCACCGCGGATGAAGTGATGAAATTCATC
GCCATGCTGCAGGGCGGACTGGTGGTGTTTCTGGGCATCACCGCTGCTTCCGCCATGGTTGTGGGAGGTTTTGTGCTGGC
CAACCTGCTGTATCTGTCCATTGCCGAGCGCCAGATGGAAATAGGGCTGCGCAAAGCCATGGGAGCCCGCAACAGCGCCA
TTGTTCTCCAGTTTCTCATCGAATCCGTGACACTGACCGTCATCGGCAGCCTGCTGGGGCTGTGCATAGGCATCGTGCTG
GGCCGTATTCTTTCCGGATTCGACCTCATCGAGCTGGAACTTTCATGGAAGGTCTTTATCATCGGCGTGGCCTCGGCCGT
AGCGGTAGGGCTTGTTTTCGGCCTGCGGCCCGCACGCAACGCGGCCGCACTGGACCCCATACACGCGCTGAAAGGAAACC
AGTAA

Upstream 100 bases:

>100_bases
GGCGTGCCGCGTTTTTCCGCGGCCGCCGGACAGCCGTTTCAGGACTTTTTTTACGCGGCGCTTACGGGTATGATAACGCA
TTGCAAGGAGCACCGTCACA

Downstream 100 bases:

>100_bases
CATGAGCAGAACCACAGGCATGCTCAGCGGTCTGCGCATCGCGCGCCAGTCGCTCTCCACCCACCGTATGCGTACAGTTC
TGGCCATGCTGGGAGTTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MKSHPHTISGSSDSVPSAGTGALSGPPDSPAQTPAQTRALHRRVIHAARVLWRIQHIAFTAVWAHRLRSAFVVTAIALGI
ASLTVIIAAVDGAQKKALEITKEFGPDAALIFGGDIFNRAVGQRLTTLTPHDARSIRQMLPGVYLVVPMRSKRGITAKAN
GNNAEVERIVGATANYAEAWNWPLSQGRDFTQADVDRGARVCLLGVDPRDKLFAGVPPLGRTVFLNNIPFTVVGVLSKRG
TSSPNARLDDRIIVPLTTLTQRFNMDRRHFPALRVKFTNAEAMDEHKEGLKSLLRHLHNLRPGDPDDFSIITADEVMKFI
AMLQGGLVVFLGITAASAMVVGGFVLANLLYLSIAERQMEIGLRKAMGARNSAIVLQFLIESVTLTVIGSLLGLCIGIVL
GRILSGFDLIELELSWKVFIIGVASAVAVGLVFGLRPARNAAALDPIHALKGNQ

Sequences:

>Translated_454_residues
MKSHPHTISGSSDSVPSAGTGALSGPPDSPAQTPAQTRALHRRVIHAARVLWRIQHIAFTAVWAHRLRSAFVVTAIALGI
ASLTVIIAAVDGAQKKALEITKEFGPDAALIFGGDIFNRAVGQRLTTLTPHDARSIRQMLPGVYLVVPMRSKRGITAKAN
GNNAEVERIVGATANYAEAWNWPLSQGRDFTQADVDRGARVCLLGVDPRDKLFAGVPPLGRTVFLNNIPFTVVGVLSKRG
TSSPNARLDDRIIVPLTTLTQRFNMDRRHFPALRVKFTNAEAMDEHKEGLKSLLRHLHNLRPGDPDDFSIITADEVMKFI
AMLQGGLVVFLGITAASAMVVGGFVLANLLYLSIAERQMEIGLRKAMGARNSAIVLQFLIESVTLTVIGSLLGLCIGIVL
GRILSGFDLIELELSWKVFIIGVASAVAVGLVFGLRPARNAAALDPIHALKGNQ
>Mature_454_residues
MKSHPHTISGSSDSVPSAGTGALSGPPDSPAQTPAQTRALHRRVIHAARVLWRIQHIAFTAVWAHRLRSAFVVTAIALGI
ASLTVIIAAVDGAQKKALEITKEFGPDAALIFGGDIFNRAVGQRLTTLTPHDARSIRQMLPGVYLVVPMRSKRGITAKAN
GNNAEVERIVGATANYAEAWNWPLSQGRDFTQADVDRGARVCLLGVDPRDKLFAGVPPLGRTVFLNNIPFTVVGVLSKRG
TSSPNARLDDRIIVPLTTLTQRFNMDRRHFPALRVKFTNAEAMDEHKEGLKSLLRHLHNLRPGDPDDFSIITADEVMKFI
AMLQGGLVVFLGITAASAMVVGGFVLANLLYLSIAERQMEIGLRKAMGARNSAIVLQFLIESVTLTVIGSLLGLCIGIVL
GRILSGFDLIELELSWKVFIIGVASAVAVGLVFGLRPARNAAALDPIHALKGNQ

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=397, Percent_Identity=27.9596977329975, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 48859; Mature: 48859

Theoretical pI: Translated: 10.83; Mature: 10.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSHPHTISGSSDSVPSAGTGALSGPPDSPAQTPAQTRALHRRVIHAARVLWRIQHIAFT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AVWAHRLRSAFVVTAIALGIASLTVIIAAVDGAQKKALEITKEFGPDAALIFGGDIFNRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECHHHHHHH
VGQRLTTLTPHDARSIRQMLPGVYLVVPMRSKRGITAKANGNNAEVERIVGATANYAEAW
HHHHHCCCCCCHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCHHHHHHHCCCCCHHHHC
NWPLSQGRDFTQADVDRGARVCLLGVDPRDKLFAGVPPLGRTVFLNNIPFTVVGVLSKRG
CCCHHCCCCCCHHHHCCCCEEEEEECCCHHHHHCCCCCCCCEEEECCCCHHHHHHHHHCC
TSSPNARLDDRIIVPLTTLTQRFNMDRRHFPALRVKFTNAEAMDEHKEGLKSLLRHLHNL
CCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCC
RPGDPDDFSIITADEVMKFIAMLQGGLVVFLGITAASAMVVGGFVLANLLYLSIAERQME
CCCCCCCEEEEEHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGLRKAMGARNSAIVLQFLIESVTLTVIGSLLGLCIGIVLGRILSGFDLIELELSWKVFI
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEEEEE
IGVASAVAVGLVFGLRPARNAAALDPIHALKGNQ
EEHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCC
>Mature Secondary Structure
MKSHPHTISGSSDSVPSAGTGALSGPPDSPAQTPAQTRALHRRVIHAARVLWRIQHIAFT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AVWAHRLRSAFVVTAIALGIASLTVIIAAVDGAQKKALEITKEFGPDAALIFGGDIFNRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECHHHHHHH
VGQRLTTLTPHDARSIRQMLPGVYLVVPMRSKRGITAKANGNNAEVERIVGATANYAEAW
HHHHHCCCCCCHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCHHHHHHHCCCCCHHHHC
NWPLSQGRDFTQADVDRGARVCLLGVDPRDKLFAGVPPLGRTVFLNNIPFTVVGVLSKRG
CCCHHCCCCCCHHHHCCCCEEEEEECCCHHHHHCCCCCCCCEEEECCCCHHHHHHHHHCC
TSSPNARLDDRIIVPLTTLTQRFNMDRRHFPALRVKFTNAEAMDEHKEGLKSLLRHLHNL
CCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCC
RPGDPDDFSIITADEVMKFIAMLQGGLVVFLGITAASAMVVGGFVLANLLYLSIAERQME
CCCCCCCEEEEEHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGLRKAMGARNSAIVLQFLIESVTLTVIGSLLGLCIGIVLGRILSGFDLIELELSWKVFI
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEEEEE
IGVASAVAVGLVFGLRPARNAAALDPIHALKGNQ
EEHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA