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The map label for this gene is macB [H]

Identifier: 78356382

GI number: 78356382

Start: 1352913

End: 1354148

Strand: Reverse

Name: macB [H]

Synonym: Dde_1335

Alternate gene names: 78356382

Gene position: 1354148-1352913 (Counterclockwise)

Preceding gene: 78356383

Following gene: 78356381

Centisome position: 36.3

GC content: 58.17

Gene sequence:

>1236_bases
ATGAGCAGAACCACAGGCATGCTCAGCGGTCTGCGCATCGCGCGCCAGTCGCTCTCCACCCACCGTATGCGTACAGTTCT
GGCCATGCTGGGAGTTTTTCTGGGTGCCATGGTGCTTACCGGCGTGCTTCATATTTCCAAATCGCTGGTGCGCAAGGCTG
AAATAGAAACAGAAAAACTGGGGCCCAACCTGTTTCAGGCAGCATCCGGCACCATCAGCTTCCGCAGAAGCGGTTCTGCA
CGCTTCAGAGGAGAAACCACCACGTTTTCCCTGCGCGACGCCGAAGCACTGTTACGTTCTGTACCGCAGATAGAAAAAGG
CGTGCCCTATGTCACCCGCACCATGCCCATCCGCAAAGGACGTATGGCCACGCAGTGTCAGCTGGTGGCCACCCTGCCGC
TGTACACCGACGTGCGCAATATCGAAATTGATGCGGGCCGGTTCTTCACCTCTCGCGAGGTGGAAGAAATGGCTAAAGTC
ATCGTGCTGGGCCGTACCATTGCGGAACGGCTGTTCGGTTCCCCTGCACAGGCTCTGGGCCAGACGGTTTTCTTTTACCG
CGCCAACCTTACCGTAGTCGGCATAATGGCCGAAAAAGGCAGTGATCTTTCCGGTACCGATCAGGACGAACAGGTATTTG
TGCCGCTGACAACCTACATGCGGCGCATGTCAAACCAGACATGGGTTTCGGGCGTGTTCATGAACCTGAAACGCGGCGCT
TCGGAAGACGCCGCACGCAGAGCCGCCACGGAGATACTGCGGCAGCGCCACGGCACTTCCGGAAATGATGACGACTTTTC
CATCCTTACCGCACGCGAAGCCACGCAATTGCAGAAAAAGGCTCTGGATCTCGTATGGACGCTGGGACTGCTTTCCTCCG
GCATTTCTTTTTCCGTCGGCAGTCTGGGCATTCTGTCCATAATGATTCTGCTGGTCCGCGCCCGCCGGCTGGAGATAGGC
ATACGCCGCTCTGTGGGAGCCACGCGGGGCAACATCATGGGACAGTTTCTTATGGAATCAGCCATCATGGCCGGTGCTGG
CGGCGCCGCAGGCGTGATCACGTCAGCCGGACTGATTACAATTGTCTACTATTTTGCCGGCCTGCCGTTTGTATACGACC
CGCTGCTCATCGGCGGCATATGCGCAGGCTCCGTTCTGCTGGGACTGGCCGCAGGGGCCTATCCGGCCTGGCAGGCATCG
CGCCTTGAAATTCTGGCCGTACTGCGCAGCGCATGA

Upstream 100 bases:

>100_bases
GTGGCCTCGGCCGTAGCGGTAGGGCTTGTTTTCGGCCTGCGGCCCGCACGCAACGCGGCCGCACTGGACCCCATACACGC
GCTGAAAGGAAACCAGTAAC

Downstream 100 bases:

>100_bases
CGGTGGCCGCACATTGCGCGCCATCGCAAACCACGATATGCCGGATAAAAACAATCCACCGGCGCCCGCACCCGTTTCAG
GCAGATGCGGTGCATACAGA

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSRTTGMLSGLRIARQSLSTHRMRTVLAMLGVFLGAMVLTGVLHISKSLVRKAEIETEKLGPNLFQAASGTISFRRSGSA
RFRGETTTFSLRDAEALLRSVPQIEKGVPYVTRTMPIRKGRMATQCQLVATLPLYTDVRNIEIDAGRFFTSREVEEMAKV
IVLGRTIAERLFGSPAQALGQTVFFYRANLTVVGIMAEKGSDLSGTDQDEQVFVPLTTYMRRMSNQTWVSGVFMNLKRGA
SEDAARRAATEILRQRHGTSGNDDDFSILTAREATQLQKKALDLVWTLGLLSSGISFSVGSLGILSIMILLVRARRLEIG
IRRSVGATRGNIMGQFLMESAIMAGAGGAAGVITSAGLITIVYYFAGLPFVYDPLLIGGICAGSVLLGLAAGAYPAWQAS
RLEILAVLRSA

Sequences:

>Translated_411_residues
MSRTTGMLSGLRIARQSLSTHRMRTVLAMLGVFLGAMVLTGVLHISKSLVRKAEIETEKLGPNLFQAASGTISFRRSGSA
RFRGETTTFSLRDAEALLRSVPQIEKGVPYVTRTMPIRKGRMATQCQLVATLPLYTDVRNIEIDAGRFFTSREVEEMAKV
IVLGRTIAERLFGSPAQALGQTVFFYRANLTVVGIMAEKGSDLSGTDQDEQVFVPLTTYMRRMSNQTWVSGVFMNLKRGA
SEDAARRAATEILRQRHGTSGNDDDFSILTAREATQLQKKALDLVWTLGLLSSGISFSVGSLGILSIMILLVRARRLEIG
IRRSVGATRGNIMGQFLMESAIMAGAGGAAGVITSAGLITIVYYFAGLPFVYDPLLIGGICAGSVLLGLAAGAYPAWQAS
RLEILAVLRSA
>Mature_410_residues
SRTTGMLSGLRIARQSLSTHRMRTVLAMLGVFLGAMVLTGVLHISKSLVRKAEIETEKLGPNLFQAASGTISFRRSGSAR
FRGETTTFSLRDAEALLRSVPQIEKGVPYVTRTMPIRKGRMATQCQLVATLPLYTDVRNIEIDAGRFFTSREVEEMAKVI
VLGRTIAERLFGSPAQALGQTVFFYRANLTVVGIMAEKGSDLSGTDQDEQVFVPLTTYMRRMSNQTWVSGVFMNLKRGAS
EDAARRAATEILRQRHGTSGNDDDFSILTAREATQLQKKALDLVWTLGLLSSGISFSVGSLGILSIMILLVRARRLEIGI
RRSVGATRGNIMGQFLMESAIMAGAGGAAGVITSAGLITIVYYFAGLPFVYDPLLIGGICAGSVLLGLAAGAYPAWQASR
LEILAVLRSA

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=410, Percent_Identity=24.1463414634146, Blast_Score=115, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44454; Mature: 44322

Theoretical pI: Translated: 10.86; Mature: 10.86

Prosite motif: PS01072 SLH_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTTGMLSGLRIARQSLSTHRMRTVLAMLGVFLGAMVLTGVLHISKSLVRKAEIETEKL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
GPNLFQAASGTISFRRSGSARFRGETTTFSLRDAEALLRSVPQIEKGVPYVTRTMPIRKG
CCHHHHHCCCCEEEECCCCCEECCCCEEEEHHHHHHHHHHCCHHHHCCCCEEECCCCCCC
RMATQCQLVATLPLYTDVRNIEIDAGRFFTSREVEEMAKVIVLGRTIAERLFGSPAQALG
CCHHHEEEEEECCHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
QTVFFYRANLTVVGIMAEKGSDLSGTDQDEQVFVPLTTYMRRMSNQTWVSGVFMNLKRGA
CEEEEEECCEEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHCCC
SEDAARRAATEILRQRHGTSGNDDDFSILTAREATQLQKKALDLVWTLGLLSSGISFSVG
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SLGILSIMILLVRARRLEIGIRRSVGATRGNIMGQFLMESAIMAGAGGAAGVITSAGLIT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
IVYYFAGLPFVYDPLLIGGICAGSVLLGLAAGAYPAWQASRLEILAVLRSA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SRTTGMLSGLRIARQSLSTHRMRTVLAMLGVFLGAMVLTGVLHISKSLVRKAEIETEKL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
GPNLFQAASGTISFRRSGSARFRGETTTFSLRDAEALLRSVPQIEKGVPYVTRTMPIRKG
CCHHHHHCCCCEEEECCCCCEECCCCEEEEHHHHHHHHHHCCHHHHCCCCEEECCCCCCC
RMATQCQLVATLPLYTDVRNIEIDAGRFFTSREVEEMAKVIVLGRTIAERLFGSPAQALG
CCHHHEEEEEECCHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
QTVFFYRANLTVVGIMAEKGSDLSGTDQDEQVFVPLTTYMRRMSNQTWVSGVFMNLKRGA
CEEEEEECCEEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHCCC
SEDAARRAATEILRQRHGTSGNDDDFSILTAREATQLQKKALDLVWTLGLLSSGISFSVG
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SLGILSIMILLVRARRLEIGIRRSVGATRGNIMGQFLMESAIMAGAGGAAGVITSAGLIT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
IVYYFAGLPFVYDPLLIGGICAGSVLLGLAAGAYPAWQASRLEILAVLRSA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA