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The map label for this gene is pepQ [H]

Identifier: 78356352

GI number: 78356352

Start: 1323969

End: 1325213

Strand: Direct

Name: pepQ [H]

Synonym: Dde_1305

Alternate gene names: 78356352

Gene position: 1323969-1325213 (Clockwise)

Preceding gene: 78356347

Following gene: 78356356

Centisome position: 35.49

GC content: 60.48

Gene sequence:

>1245_bases
ATGCCTTCAGTTTCAGCGGGGCGTTTTGCCGCAGCGGAAAGAATGCCGGAAGATGAGCTGCAGCAGCGGCATGAACGCCT
GCGCGGCATCATGCACCGGCGTGTGCCTGCGGCTTCGGGCATGCTGGTTTTTTCACGCGTCAATATTTATTACCTGACCG
GAACGCTGGGCAACGGCGTATTGTGGCTGCCCGTGCAGGGTGACCCCGTGCTTATGCTGCGCAGGGGGCTGCAGCGGGCC
CGTGCAGAAAGTCCTTTGCGGCATATCGTGCCCTTCCGTTCGTTTTCAGACGTGATGCCGCGCTGTTCCGATGCCGGTGT
GCCTGTGGGCGATGTGGCCGCCGTGGAACAGGGCGGGCTGACGTGGCAGCTGGGGGCCATGCTGCAGGAACGCATGGGCG
GGGTGTCTTTTGCACCCGCAGACAGTTGTCTGAGCGCCTGCCGCAGCGTGAAGACAGAGTGGGAACTGAAGAAAATGCGG
CTGGCAGGGGCGCGGCATCATCAGGCTTTGCGGCATCTGCTGCCCGACAGCCTGCATGCGGGCATGACGGAGCGTCAGGT
GGCCCATGCAGGCTGGCAGGTTTTTTACAGTCTGGGGCACTGCGGCATGATGCGCATGAACGCCGCCGGAGAAGAGATTT
TTCTGGGGCATGTCTGCGCGGGCGACAGCGGCAATTATCCCAGCCATTTTAACGGGCCGCTGGGGCTTGTGGGCGAACAT
CCGGCTGTGCCGGCCATGGGTTATGCCGGAAAGGTGTGGCAGAAAGGGCAGGTGCTTTCGTGTGATATCGGTTTTTGTCT
GGAAGGGTACCACACGGACAAGACGCAGATATACTTTGCCGGTGCAGCTGCTGCCGTGCCCGATGTCGTGCGCCGGGCGC
ATGATGTATGCGTGATGATACAGCAGAAGACCGCTGAGGCATTGAAACCCGGTGCCGTCCCTTCCGAACTGTACGCACAG
GCACTGCAGACTGCGCGGCGCGAGGGATTTGAGGCCGGATTCATGGGCGTGGACGACAGAAAGGTGGCTTTTCTGGGGCA
CGGCATCGGTCTGGCCATTGATGATCAGCCCGTTATTGCCGCCCGTTTTGACGCACCTGTGGAAAAAGGTATGGTCTTTG
CGCTGGAGCCGAAGATAGGCATTGAGGGAACCGGCATGGTGGGCGTTGAAAACACGTATGAAGTGACGGAAGACGGCTGC
CGGTGCCTTACGGGTGACGATTTCGGTATTGTGTGCGTGGAGTAG

Upstream 100 bases:

>100_bases
CTGTGCAGCGTTGCGCCGGTGCGGACGTTGTTCTACAAGCAGATGAGATATCCGGGCGCGCATACGAGCTGCCTTGTCCT
TTTACTTTACAGGAGTTGAT

Downstream 100 bases:

>100_bases
CCTGCGGCGCGGTCAGGCTCCGGAGTGCGTGTAACCGGTGCTGCGGACGTAGCGGGTTGCTTTTGTTTATTAGCGGAAGG
GGCGGAAAAAAGACAGCCCC

Product: M24 family peptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MPSVSAGRFAAAERMPEDELQQRHERLRGIMHRRVPAASGMLVFSRVNIYYLTGTLGNGVLWLPVQGDPVLMLRRGLQRA
RAESPLRHIVPFRSFSDVMPRCSDAGVPVGDVAAVEQGGLTWQLGAMLQERMGGVSFAPADSCLSACRSVKTEWELKKMR
LAGARHHQALRHLLPDSLHAGMTERQVAHAGWQVFYSLGHCGMMRMNAAGEEIFLGHVCAGDSGNYPSHFNGPLGLVGEH
PAVPAMGYAGKVWQKGQVLSCDIGFCLEGYHTDKTQIYFAGAAAAVPDVVRRAHDVCVMIQQKTAEALKPGAVPSELYAQ
ALQTARREGFEAGFMGVDDRKVAFLGHGIGLAIDDQPVIAARFDAPVEKGMVFALEPKIGIEGTGMVGVENTYEVTEDGC
RCLTGDDFGIVCVE

Sequences:

>Translated_414_residues
MPSVSAGRFAAAERMPEDELQQRHERLRGIMHRRVPAASGMLVFSRVNIYYLTGTLGNGVLWLPVQGDPVLMLRRGLQRA
RAESPLRHIVPFRSFSDVMPRCSDAGVPVGDVAAVEQGGLTWQLGAMLQERMGGVSFAPADSCLSACRSVKTEWELKKMR
LAGARHHQALRHLLPDSLHAGMTERQVAHAGWQVFYSLGHCGMMRMNAAGEEIFLGHVCAGDSGNYPSHFNGPLGLVGEH
PAVPAMGYAGKVWQKGQVLSCDIGFCLEGYHTDKTQIYFAGAAAAVPDVVRRAHDVCVMIQQKTAEALKPGAVPSELYAQ
ALQTARREGFEAGFMGVDDRKVAFLGHGIGLAIDDQPVIAARFDAPVEKGMVFALEPKIGIEGTGMVGVENTYEVTEDGC
RCLTGDDFGIVCVE
>Mature_413_residues
PSVSAGRFAAAERMPEDELQQRHERLRGIMHRRVPAASGMLVFSRVNIYYLTGTLGNGVLWLPVQGDPVLMLRRGLQRAR
AESPLRHIVPFRSFSDVMPRCSDAGVPVGDVAAVEQGGLTWQLGAMLQERMGGVSFAPADSCLSACRSVKTEWELKKMRL
AGARHHQALRHLLPDSLHAGMTERQVAHAGWQVFYSLGHCGMMRMNAAGEEIFLGHVCAGDSGNYPSHFNGPLGLVGEHP
AVPAMGYAGKVWQKGQVLSCDIGFCLEGYHTDKTQIYFAGAAAAVPDVVRRAHDVCVMIQQKTAEALKPGAVPSELYAQA
LQTARREGFEAGFMGVDDRKVAFLGHGIGLAIDDQPVIAARFDAPVEKGMVFALEPKIGIEGTGMVGVENTYEVTEDGCR
CLTGDDFGIVCVE

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=289, Percent_Identity=24.2214532871972, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 44801; Mature: 44670

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSVSAGRFAAAERMPEDELQQRHERLRGIMHRRVPAASGMLVFSRVNIYYLTGTLGNGV
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEEECCCCE
LWLPVQGDPVLMLRRGLQRARAESPLRHIVPFRSFSDVMPRCSDAGVPVGDVAAVEQGGL
EEEEECCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHCCCCCCCCCCCCCHHHHHCCCC
TWQLGAMLQERMGGVSFAPADSCLSACRSVKTEWELKKMRLAGARHHQALRHLLPDSLHA
EEHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHC
GMTERQVAHAGWQVFYSLGHCGMMRMNAAGEEIFLGHVCAGDSGNYPSHFNGPLGLVGEH
CCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCC
PAVPAMGYAGKVWQKGQVLSCDIGFCLEGYHTDKTQIYFAGAAAAVPDVVRRAHDVCVMI
CCCCCCCCCCCCCCCCCEEEECCCCEECCEECCCEEEEEECCHHHHHHHHHHHHHHEEEE
QQKTAEALKPGAVPSELYAQALQTARREGFEAGFMGVDDRKVAFLGHGIGLAIDDQPVIA
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEECCCCEEE
ARFDAPVEKGMVFALEPKIGIEGTGMVGVENTYEVTEDGCRCLTGDDFGIVCVE
EECCCCHHHCEEEEECCCCCCCCCCEECCCCCHHHCCCCCEEECCCCEEEEEEC
>Mature Secondary Structure 
PSVSAGRFAAAERMPEDELQQRHERLRGIMHRRVPAASGMLVFSRVNIYYLTGTLGNGV
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEEECCCCE
LWLPVQGDPVLMLRRGLQRARAESPLRHIVPFRSFSDVMPRCSDAGVPVGDVAAVEQGGL
EEEEECCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHCCCCCCCCCCCCCHHHHHCCCC
TWQLGAMLQERMGGVSFAPADSCLSACRSVKTEWELKKMRLAGARHHQALRHLLPDSLHA
EEHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHC
GMTERQVAHAGWQVFYSLGHCGMMRMNAAGEEIFLGHVCAGDSGNYPSHFNGPLGLVGEH
CCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCC
PAVPAMGYAGKVWQKGQVLSCDIGFCLEGYHTDKTQIYFAGAAAAVPDVVRRAHDVCVMI
CCCCCCCCCCCCCCCCCEEEECCCCEECCEECCCEEEEEECCHHHHHHHHHHHHHHEEEE
QQKTAEALKPGAVPSELYAQALQTARREGFEAGFMGVDDRKVAFLGHGIGLAIDDQPVIA
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEECCCCEEE
ARFDAPVEKGMVFALEPKIGIEGTGMVGVENTYEVTEDGCRCLTGDDFGIVCVE
EECCCCHHHCEEEEECCCCCCCCCCEECCCCCHHHCCCCCEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]