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The map label for this gene is glcB [H]

Identifier: 78356221

GI number: 78356221

Start: 1200789

End: 1202975

Strand: Direct

Name: glcB [H]

Synonym: Dde_1174

Alternate gene names: 78356221

Gene position: 1200789-1202975 (Clockwise)

Preceding gene: 78356220

Following gene: 78356224

Centisome position: 32.19

GC content: 59.49

Gene sequence:

>2187_bases
ATGACAACAAGAACACAGACCGGCGGTCTGCAGGTGGCATCGTGCCTTTCCTGCCTTGTCGCCAATGAGATAGCGCCGGA
TACGGGTGTCGACCCTGTGGATTTCTGGGCGGGCGCCGAAGCATTGTTCAGGGATTTTGCGCCGCGTAACAAAGAGCTGC
TGGAACTGCGCGAAAGCATGCAGCAGTCCGTTGACGCGTGGCACCGCGAACGTGCCGGCAAGCCCCACGATGCGGCGGAA
TACAAGGCGTTTCTGGAAAAAACAGGCTATCTGCTGCCTGAAGGGGAGGATTTTACCATTTCTCCTGAGAATGTGGACCC
GGAAATAGCCGAGGTTGCCGGACCGCAGCTGGTAGTGCCCATTACCAACGCCCGTTATGCCGTCAATGCGGCCAATGCCC
GTTGGGGCAGCCTGTATGACGCTCTGTACGGCACCGACGTGATCGCTGAAACGGACGGCATGGAAAAAGGGCCGGACTAC
AATCCGGTGCGGGGCCGCGAGGTAATGCGTCTTGCAACGGCGTTTCTGGACAAAGCAGTGCCGCTGGACGGAATGTCGCA
TGGTGATGTGACTGCGTATATCCTGCTTCGGGACGGCCGGCGCCGTGTGCTGGCGGCCCGCGACGCATCGGGGAAAGAGA
CGGGACTCGCCGCGCCGGAGCAGTTTGTCGGTTTTTCCGGCGGTGATGCGCCTGCCGTGGTTGTTCTGCGCAATAACGGC
CTGCATATTGAGCTGCATGTGGACAGAACGCATCCCGTGGGGGCGGCGCATCCTGCCGGTGTGAAAGATGTGGTCCTTGA
AGCGGCAGTGACTACCATTCAGGACTGCGAAGATTCTGTAAGCGCCGTGGATGCCCACGACAAGACCAGAACGTACCAGT
CATGGCTGGGGCTGATCAAAGGCGATCTGGAAGCCAGCTTTGTGAAGGACGGAACACTGCGCGTGCGCACGCTCAATCCG
GACAGGGAATATACGGCGCCTGACGGCAGCGCTCTTGTGCTGCCCGGCCGCAGCCTGATGCTTATCCGCAACGTGGGGCA
TCTTATGACCACGGATGCCGTGCTGACGGAGGACGGCAGCCCCGTACCGGAGGGGATTCTGGACGCTCTGATGACAGGCT
ATGTGGCGCTGCACGAACTGAAGGGCAACGTACGCTACCGCAACAGCCGCACAGGCAGTGTGTATATCGTCAAGCCCAAG
ATGCACGGTCCGGAGGAAGTCCGCTTCACCTGCGATCTTTTCAGCAGGGTGGAGGATATTCTGGGACTGCCCCGTCATAT
GCTCAAGGTGGGGATTATGGATGAAGAGCGCCGCACGTCGCTGAATCTTAAAGAGTGCATCCGCGCGGCCCGCGAACGGG
TTATTTTTATCAATACCGGCTTTCTGGATCGTACCGGCGACGAGATTCATACCTGCATGGAGGCGGGGCCGGTTGTCAGA
AAGAATGATATGAAGGCGGAGCGCTGGATAGCTGCATACGAGGACTGGAACGTGGATGTGGGGCTGGCCTGCGGTTTTTC
GGGCAGGGCGCAGATAGGCAAGGGCATGTGGCCCAAGCCCGACAGCATGCGCGAAATGCTGGAAACCAAAGGGGCGCATC
CCCGCGCGGGTGCAGGTTGCGCATGGGTGCCCTCGCCTGCTGCAGCCACGCTGCATGCCATGCATTATCATGATGTGAAC
GTGCGCGATGTCCAGACAGCGCTGGCCGCCCGACGGCGCGCCTGCCGTGATGACATGCTGGTGCTGCCGCTGCTGCGTTC
GGCACCTGATGCAGGTGCTGTGCGTGAAGAACTGGAAAATAACATCCAGAGCATACTCGGATACGTGGTGCGCTGGATCG
AGCAGGGAATCGGTTGTTCCAAGGTGCCTGATATTCACAATGTGGGGCTGATGGAAGACCGTGCCACACTGCGTATTTCC
AGTCAGCATATCGCCAACTGGCTGCATCACGGCGTATGCACGCGGGAAGAAGTTATGGCCGTGTTTAAAAAAATGGCCGC
AGTGGTGGATTCGCAGAATGCCGGACATCAGGCGTACACGCCCATGGCGCCTGATTTTGAACGCAGCATCGCCTTTCAGG
CGGCGTGTGATCTGGTTTTCAAGGGGCGCGAGCAGCCCAGCGGCTATACCGAGCCGGTGCTGCACCAGCGCAGGCGCGAA
GCAAAAACGCGTTTCGGGCAGGTGTAA

Upstream 100 bases:

>100_bases
TTTTCCAGCTTTTTTGCCGGCAGTATGTCTTTGCGCCTCCGGGCCGCATAACTGCCGTGTTCCGCTGCAACCCTAACCTA
CGCCATTCGGGGGTTACATA

Downstream 100 bases:

>100_bases
ACGGCCGGAGCATTCGGGCAGCTGCGCTGTCCGGCCGCATTGCCGGATACGGCAGGGCATGCCGGTCCGGCCCGAGCAGG
CAGGTTTGTTAATCAGGGCG

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 728; Mature: 727

Protein sequence:

>728_residues
MTTRTQTGGLQVASCLSCLVANEIAPDTGVDPVDFWAGAEALFRDFAPRNKELLELRESMQQSVDAWHRERAGKPHDAAE
YKAFLEKTGYLLPEGEDFTISPENVDPEIAEVAGPQLVVPITNARYAVNAANARWGSLYDALYGTDVIAETDGMEKGPDY
NPVRGREVMRLATAFLDKAVPLDGMSHGDVTAYILLRDGRRRVLAARDASGKETGLAAPEQFVGFSGGDAPAVVVLRNNG
LHIELHVDRTHPVGAAHPAGVKDVVLEAAVTTIQDCEDSVSAVDAHDKTRTYQSWLGLIKGDLEASFVKDGTLRVRTLNP
DREYTAPDGSALVLPGRSLMLIRNVGHLMTTDAVLTEDGSPVPEGILDALMTGYVALHELKGNVRYRNSRTGSVYIVKPK
MHGPEEVRFTCDLFSRVEDILGLPRHMLKVGIMDEERRTSLNLKECIRAARERVIFINTGFLDRTGDEIHTCMEAGPVVR
KNDMKAERWIAAYEDWNVDVGLACGFSGRAQIGKGMWPKPDSMREMLETKGAHPRAGAGCAWVPSPAAATLHAMHYHDVN
VRDVQTALAARRRACRDDMLVLPLLRSAPDAGAVREELENNIQSILGYVVRWIEQGIGCSKVPDIHNVGLMEDRATLRIS
SQHIANWLHHGVCTREEVMAVFKKMAAVVDSQNAGHQAYTPMAPDFERSIAFQAACDLVFKGREQPSGYTEPVLHQRRRE
AKTRFGQV

Sequences:

>Translated_728_residues
MTTRTQTGGLQVASCLSCLVANEIAPDTGVDPVDFWAGAEALFRDFAPRNKELLELRESMQQSVDAWHRERAGKPHDAAE
YKAFLEKTGYLLPEGEDFTISPENVDPEIAEVAGPQLVVPITNARYAVNAANARWGSLYDALYGTDVIAETDGMEKGPDY
NPVRGREVMRLATAFLDKAVPLDGMSHGDVTAYILLRDGRRRVLAARDASGKETGLAAPEQFVGFSGGDAPAVVVLRNNG
LHIELHVDRTHPVGAAHPAGVKDVVLEAAVTTIQDCEDSVSAVDAHDKTRTYQSWLGLIKGDLEASFVKDGTLRVRTLNP
DREYTAPDGSALVLPGRSLMLIRNVGHLMTTDAVLTEDGSPVPEGILDALMTGYVALHELKGNVRYRNSRTGSVYIVKPK
MHGPEEVRFTCDLFSRVEDILGLPRHMLKVGIMDEERRTSLNLKECIRAARERVIFINTGFLDRTGDEIHTCMEAGPVVR
KNDMKAERWIAAYEDWNVDVGLACGFSGRAQIGKGMWPKPDSMREMLETKGAHPRAGAGCAWVPSPAAATLHAMHYHDVN
VRDVQTALAARRRACRDDMLVLPLLRSAPDAGAVREELENNIQSILGYVVRWIEQGIGCSKVPDIHNVGLMEDRATLRIS
SQHIANWLHHGVCTREEVMAVFKKMAAVVDSQNAGHQAYTPMAPDFERSIAFQAACDLVFKGREQPSGYTEPVLHQRRRE
AKTRFGQV
>Mature_727_residues
TTRTQTGGLQVASCLSCLVANEIAPDTGVDPVDFWAGAEALFRDFAPRNKELLELRESMQQSVDAWHRERAGKPHDAAEY
KAFLEKTGYLLPEGEDFTISPENVDPEIAEVAGPQLVVPITNARYAVNAANARWGSLYDALYGTDVIAETDGMEKGPDYN
PVRGREVMRLATAFLDKAVPLDGMSHGDVTAYILLRDGRRRVLAARDASGKETGLAAPEQFVGFSGGDAPAVVVLRNNGL
HIELHVDRTHPVGAAHPAGVKDVVLEAAVTTIQDCEDSVSAVDAHDKTRTYQSWLGLIKGDLEASFVKDGTLRVRTLNPD
REYTAPDGSALVLPGRSLMLIRNVGHLMTTDAVLTEDGSPVPEGILDALMTGYVALHELKGNVRYRNSRTGSVYIVKPKM
HGPEEVRFTCDLFSRVEDILGLPRHMLKVGIMDEERRTSLNLKECIRAARERVIFINTGFLDRTGDEIHTCMEAGPVVRK
NDMKAERWIAAYEDWNVDVGLACGFSGRAQIGKGMWPKPDSMREMLETKGAHPRAGAGCAWVPSPAAATLHAMHYHDVNV
RDVQTALAARRRACRDDMLVLPLLRSAPDAGAVREELENNIQSILGYVVRWIEQGIGCSKVPDIHNVGLMEDRATLRISS
QHIANWLHHGVCTREEVMAVFKKMAAVVDSQNAGHQAYTPMAPDFERSIAFQAACDLVFKGREQPSGYTEPVLHQRRREA
KTRFGQV

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=729, Percent_Identity=54.320987654321, Blast_Score=791, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561814, Length=266, Percent_Identity=26.3157894736842, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 80094; Mature: 79963

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRTQTGGLQVASCLSCLVANEIAPDTGVDPVDFWAGAEALFRDFAPRNKELLELRESM
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHCCCCCHHHHHHHHHH
QQSVDAWHRERAGKPHDAAEYKAFLEKTGYLLPEGEDFTISPENVDPEIAEVAGPQLVVP
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHCCCEEEEE
ITNARYAVNAANARWGSLYDALYGTDVIAETDGMEKGPDYNPVRGREVMRLATAFLDKAV
ECCCEEEEECCCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
PLDGMSHGDVTAYILLRDGRRRVLAARDASGKETGLAAPEQFVGFSGGDAPAVVVLRNNG
CCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCC
LHIELHVDRTHPVGAAHPAGVKDVVLEAAVTTIQDCEDSVSAVDAHDKTRTYQSWLGLIK
EEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GDLEASFVKDGTLRVRTLNPDREYTAPDGSALVLPGRSLMLIRNVGHLMTTDAVLTEDGS
CCCHHHEECCCEEEEEEECCCCCCCCCCCCEEEECCCCEEEEHHCCHHHCCCEEEECCCC
PVPEGILDALMTGYVALHELKGNVRYRNSRTGSVYIVKPKMHGPEEVRFTCDLFSRVEDI
CCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCCHHHEEHHHHHHHHHHH
LGLPRHMLKVGIMDEERRTSLNLKECIRAARERVIFINTGFLDRTGDEIHTCMEAGPVVR
HCCCHHHHHCCCCCCHHHHCCCHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHCCCCEE
KNDMKAERWIAAYEDWNVDVGLACGFSGRAQIGKGMWPKPDSMREMLETKGAHPRAGAGC
CCCCCHHHHEEECCCCCCEEEEEECCCCCHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCC
AWVPSPAAATLHAMHYHDVNVRDVQTALAARRRACRDDMLVLPLLRSAPDAGAVREELEN
CCCCCCHHHHEEHHHCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHHCCCCCHHHHHHHHH
NIQSILGYVVRWIEQGIGCSKVPDIHNVGLMEDRATLRISSQHIANWLHHGVCTREEVMA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHH
VFKKMAAVVDSQNAGHQAYTPMAPDFERSIAFQAACDLVFKGREQPSGYTEPVLHQRRRE
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AKTRFGQV
HHHHCCCC
>Mature Secondary Structure 
TTRTQTGGLQVASCLSCLVANEIAPDTGVDPVDFWAGAEALFRDFAPRNKELLELRESM
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHCCCCCHHHHHHHHHH
QQSVDAWHRERAGKPHDAAEYKAFLEKTGYLLPEGEDFTISPENVDPEIAEVAGPQLVVP
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHCCCEEEEE
ITNARYAVNAANARWGSLYDALYGTDVIAETDGMEKGPDYNPVRGREVMRLATAFLDKAV
ECCCEEEEECCCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
PLDGMSHGDVTAYILLRDGRRRVLAARDASGKETGLAAPEQFVGFSGGDAPAVVVLRNNG
CCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCC
LHIELHVDRTHPVGAAHPAGVKDVVLEAAVTTIQDCEDSVSAVDAHDKTRTYQSWLGLIK
EEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GDLEASFVKDGTLRVRTLNPDREYTAPDGSALVLPGRSLMLIRNVGHLMTTDAVLTEDGS
CCCHHHEECCCEEEEEEECCCCCCCCCCCCEEEECCCCEEEEHHCCHHHCCCEEEECCCC
PVPEGILDALMTGYVALHELKGNVRYRNSRTGSVYIVKPKMHGPEEVRFTCDLFSRVEDI
CCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCCHHHEEHHHHHHHHHHH
LGLPRHMLKVGIMDEERRTSLNLKECIRAARERVIFINTGFLDRTGDEIHTCMEAGPVVR
HCCCHHHHHCCCCCCHHHHCCCHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHCCCCEE
KNDMKAERWIAAYEDWNVDVGLACGFSGRAQIGKGMWPKPDSMREMLETKGAHPRAGAGC
CCCCCHHHHEEECCCCCCEEEEEECCCCCHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCC
AWVPSPAAATLHAMHYHDVNVRDVQTALAARRRACRDDMLVLPLLRSAPDAGAVREELEN
CCCCCCHHHHEEHHHCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHHCCCCCHHHHHHHHH
NIQSILGYVVRWIEQGIGCSKVPDIHNVGLMEDRATLRISSQHIANWLHHGVCTREEVMA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHH
VFKKMAAVVDSQNAGHQAYTPMAPDFERSIAFQAACDLVFKGREQPSGYTEPVLHQRRRE
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AKTRFGQV
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA