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The map label for this gene is ycgM [C]

Identifier: 78356185

GI number: 78356185

Start: 1167772

End: 1168566

Strand: Direct

Name: ycgM [C]

Synonym: Dde_1138

Alternate gene names: 78356185

Gene position: 1167772-1168566 (Clockwise)

Preceding gene: 78356184

Following gene: 78356186

Centisome position: 31.31

GC content: 60.5

Gene sequence:

>795_bases
ATGCGCGTGCTGAGGGTACGATATAACGGCCATTCCTTTTACGGCAGGCTGGACGGCAATCATGTGCATTGTCTCAATCC
GCAGCTGGGGCTTAACGACCCCATAGCTCTTGAGGATATTGCAGTGCTGCCTGTGGTCACTCCCTCAAAGATCGTCTGTG
TGGGGATGAATTTTCGCGACCATGCGGAAGAAATAGGCTTTCCCGTGCCGGAAGAACCGGTCTTTTTTCTCAAGCCCTCC
AGTGCCGTGATCGGCAGCGGACAGCCTGTGGTGCTGCCTGCCGAATCGGGGCGGGTGGAGCATGAAGCGGAACTGGGGGT
GGTTATCGGGCGTGCCGCACGCAATATAACTCCCGAGGATGTTCCGGCGCATGTTTTCGGCTATACCTGCGCCAACGATG
TGACGGCGCGCGACCTGCAGTCCCGTGACGGTCTTTTCGGCCGGTGCAAGGGGTTTGACACATTTGCTCCCGTGGGGCCG
TGGATAGAGACCGAAGTGCCCGACCTTTCTTCGCTGGGCATCAGAGCCATGGTGAATGGTGAACTGAGACAGCAGGGCAG
CACCGCGGATATGCTTTTTTCGCCGCACGAGATAGTGGCGGCCGTTTCCCGCGTGATGACGCTGCTGCCCGGTGATCTGA
TACTGACGGGAACCCCCGCCGGTGTGGGACCGCTGGAAGACGGCGACGAGGTGCGCGTGGAGATTGACGGCGTAGGACTG
CTCATCAACCCCGTGCTGCGGGAACCTTCCGGCAGCGGGCAGGAAGGGCCGGAGTCGGAGCCGCCTGTCCAGTGA

Upstream 100 bases:

>100_bases
TCACGGTGGTCTGACCGGCAGCAGACGCGGCGGAATGCATGGGTCCGCCGCCGTGTCATGTGTTTTTCGCAATGCAGCGA
CCTGTGAAGGAGAAAACCTG

Downstream 100 bases:

>100_bases
CAGCAATGAAGGCCTTTTTGCTCCGGCGGAAGGGCTTTTTTGATTTGCAGCCGGCCCGCCCTGTACCTGAAGCAGGCTGG
GCATACGCGCACTGCTTTGT

Product: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MRVLRVRYNGHSFYGRLDGNHVHCLNPQLGLNDPIALEDIAVLPVVTPSKIVCVGMNFRDHAEEIGFPVPEEPVFFLKPS
SAVIGSGQPVVLPAESGRVEHEAELGVVIGRAARNITPEDVPAHVFGYTCANDVTARDLQSRDGLFGRCKGFDTFAPVGP
WIETEVPDLSSLGIRAMVNGELRQQGSTADMLFSPHEIVAAVSRVMTLLPGDLILTGTPAGVGPLEDGDEVRVEIDGVGL
LINPVLREPSGSGQEGPESEPPVQ

Sequences:

>Translated_264_residues
MRVLRVRYNGHSFYGRLDGNHVHCLNPQLGLNDPIALEDIAVLPVVTPSKIVCVGMNFRDHAEEIGFPVPEEPVFFLKPS
SAVIGSGQPVVLPAESGRVEHEAELGVVIGRAARNITPEDVPAHVFGYTCANDVTARDLQSRDGLFGRCKGFDTFAPVGP
WIETEVPDLSSLGIRAMVNGELRQQGSTADMLFSPHEIVAAVSRVMTLLPGDLILTGTPAGVGPLEDGDEVRVEIDGVGL
LINPVLREPSGSGQEGPESEPPVQ
>Mature_264_residues
MRVLRVRYNGHSFYGRLDGNHVHCLNPQLGLNDPIALEDIAVLPVVTPSKIVCVGMNFRDHAEEIGFPVPEEPVFFLKPS
SAVIGSGQPVVLPAESGRVEHEAELGVVIGRAARNITPEDVPAHVFGYTCANDVTARDLQSRDGLFGRCKGFDTFAPVGP
WIETEVPDLSSLGIRAMVNGELRQQGSTADMLFSPHEIVAAVSRVMTLLPGDLILTGTPAGVGPLEDGDEVRVEIDGVGL
LINPVLREPSGSGQEGPESEPPVQ

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=216, Percent_Identity=46.7592592592593, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI40786394, Length=216, Percent_Identity=45.8333333333333, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI66348062, Length=203, Percent_Identity=43.3497536945813, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI215422413, Length=193, Percent_Identity=43.5233160621762, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI13654274, Length=193, Percent_Identity=43.5233160621762, Blast_Score=154, Evalue=8e-38,
Organism=Escherichia coli, GI1787428, Length=200, Percent_Identity=44, Blast_Score=157, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI17557057, Length=188, Percent_Identity=36.1702127659575, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324161, Length=225, Percent_Identity=35.5555555555556, Blast_Score=126, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28572127, Length=232, Percent_Identity=39.6551724137931, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24663695, Length=216, Percent_Identity=35.6481481481481, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28571789, Length=189, Percent_Identity=41.7989417989418, Blast_Score=140, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 28210; Mature: 28210

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLRVRYNGHSFYGRLDGNHVHCLNPQLGLNDPIALEDIAVLPVVTPSKIVCVGMNFRD
CEEEEEEECCCEEEEEECCCEEEEECCCCCCCCCCEECCEEEEEEECCCCEEEEECCCHH
HAEEIGFPVPEEPVFFLKPSSAVIGSGQPVVLPAESGRVEHEAELGVVIGRAARNITPED
HHHHCCCCCCCCCEEEECCCCEEECCCCEEEEECCCCCCCCCCCEEEEEECHHCCCCCCC
VPAHVFGYTCANDVTARDLQSRDGLFGRCKGFDTFAPVGPWIETEVPDLSSLGIRAMVNG
CCCEEEEEECCCCCHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCHHHCCEEEEECC
ELRQQGSTADMLFSPHEIVAAVSRVMTLLPGDLILTGTPAGVGPLEDGDEVRVEIDGVGL
HHHHCCCCHHEEECHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCEE
LINPVLREPSGSGQEGPESEPPVQ
EEEHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVLRVRYNGHSFYGRLDGNHVHCLNPQLGLNDPIALEDIAVLPVVTPSKIVCVGMNFRD
CEEEEEEECCCEEEEEECCCEEEEECCCCCCCCCCEECCEEEEEEECCCCEEEEECCCHH
HAEEIGFPVPEEPVFFLKPSSAVIGSGQPVVLPAESGRVEHEAELGVVIGRAARNITPED
HHHHCCCCCCCCCEEEECCCCEEECCCCEEEEECCCCCCCCCCCEEEEEECHHCCCCCCC
VPAHVFGYTCANDVTARDLQSRDGLFGRCKGFDTFAPVGPWIETEVPDLSSLGIRAMVNG
CCCEEEEEECCCCCHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCHHHCCEEEEECC
ELRQQGSTADMLFSPHEIVAAVSRVMTLLPGDLILTGTPAGVGPLEDGDEVRVEIDGVGL
HHHHCCCCHHEEECHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCEE
LINPVLREPSGSGQEGPESEPPVQ
EEEHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]